A forward phenotypically driven unbiased genetic analysis of host genes that moderate herpes simplex virus virulence and stromal keratitis in mice

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Thompson, Richard L ^a   Williams, Robert W ^b   Kotb, Malak ^a   Sawtell, Nancy M ^c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRALIZING ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; BXD MOUSE; C57BL 6 MOUSE; CHROMOSOME 16; CHROMOSOME MAP; CONTROLLED STUDY; DBA 2 MOUSE; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENE; GENE LOCUS; GENE SEQUENCE; GENETIC VARIABILITY; HERPES SIMPLEX; HERPES SIMPLEX ENCEPHALITIS; HERPES SIMPLEX VIRUS 1; HERPETIC LABIALIS; HOST GENE; INFECTION SENSITIVITY; MALE; MORTALITY; MOUSE; NONHUMAN; QUANTITATIVE TRAIT LOCUS; SPLEEN WEIGHT; STRAIN DIFFERENCE; STROMAL KERATITIS; TEAR FILM; VIRUS KERATITIS; VIRUS LOAD; VIRUS VIRULENCE; WEIGHT REDUCTION; X CHROMOSOME; ANIMAL; BASE PAIRING; CHROMOSOME; CORNEA STROMA; GENETICS; HERPES SIMPLEX KERATITIS; HOST PATHOGEN INTERACTION; HUMAN; PATHOGENICITY; PATHOLOGY; PHENOTYPE; SIMPLEXVIRUS; VIROLOGY; VIRULENCE;

ANIMALS; BASE PAIRING; CHROMOSOMES, MAMMALIAN; CORNEAL STROMA; FEMALE; GENES; HOST-PATHOGEN INTERACTIONS; HUMANS; KERATITIS, HERPETIC; MALE; MICE; PHENOTYPE; QUANTITATIVE TRAIT LOCI; SIMPLEXVIRUS; VIRULENCE;

EID: 84925283603     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092342     Document Type: Article

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