Quantitative trait loci contributing to phencyclidine-induced and amphetamine-induced locomotor behavior in inbred mice

Neuropsychopharmacology

Volumn 15, Issue 5, 1996, Pages 484-490

  Alexander, Robert C ^b   Wright, Renee ^a   Freed, William ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Amphetamine; Inbred mice; Locomotor activity; Model psychosis; Phencyclidine

Indexed keywords

AMPHETAMINE; PHENCYCLIDINE;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CHROMOSOMAL PARAMETERS; FEMALE; GENETICS; LOCOMOTION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMPHETAMINE; ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GENETIC MARKERS; MICE; MICE, INBRED STRAINS; MOTOR ACTIVITY; PHENCYCLIDINE;

EID: 0030297902     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(96)00058-9     Document Type: Article

References (35)

1. Alexander RC, Giordano M, Freed W (1994): Genetics of PCP-induced behavior in inbred mice. Schizophr Res 11:143
2. Allen RM, Young S (1978): Phencyclidine-induced psychosis. Am J Psychiatry 135:1081-1084
3. Belknap J (1992): Empirical estimates of Bonferroni corrections for use in chromosome mapping studies with the BXD recombinant inbred strains. Behav Genet 22:677-684
4. Belknap J, Metten P, Helms M, O'Toole S, Angeli-Gade S, Crabbe J, Phillips T (1993): QTL applications to substances of abuse: Physical dependence studies with nitrous oxide and ethanol in BXD mice. Behav Genet 23:213-222
5. Belknap J, Mitchell S, O'Toole L, Helms M, Crabbe J (1996): Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombinant inbred strains. Behav Genet (in press)
6. Belknap J, Mogil J, Helms M, Richards S, O'Toole L, Bergeson S, Buck K (1995): Localization of chromosome 10 of a locus influencing morphine analgesia in crosses derived from C57BL/6 and DBA/2 strains. Life Sci 57:PL 117-124
7. Bell D (1965): Comparison of amphetamine psychosis and schizophrenia. Br J Psychiatry 3:701-707
8. Carney J, Seale TW, Bardo M, Dwoskin L (1992): Qualitative and quantitative difference in the behavioral effects of phencyclidine in inbred mice. In Kamemka J-M, Domino EF (eds), Multiple Sigma and PCP Receptor Ligands: Mechanisms for Neuromodulation and Neuroprotection? Ann Arbor, NPP Books, pp 607-618
9. Copeland NG, Jenkins NA, Gilbert DJ, Eppig JT, Maltais LJ, Miller JC, Dietrich WF, Weaver A, Lincoln SE, Steen RG, Stein LD, Nadeau JH, Lander ES (1993): A genetic linkage map of the mouse: Current applications and future prospects. Science 262(5130):57-66
10. Domino EF, Luby ED (1981): Abnormal mental states induced by phencyclidine as a model of schizophrenia. In Domino EF (ed), PCP (Phencyclidine): Historical and Current Perspectives, Ann Arbor, NPP Books, pp 401-418
11. Dwoskin L, Carney J (1992): Genetic isolation of in vivo and in vitro PCP responsiveness. In Kamemka J-M, Domino EF (eds), Multiple Sigma and PCP Receptor Ligands: Mechanisms for Neuromodulation and Neuroprotection? Ann Arbor, MI, NPP Books, pp 850-877
12. Ellison GD, Eison MS (1983): Continuous amphetamine intoxication: An animal model of the acute psychotic episode. Psychol Med 13:751-761
13. Falconer DS (1989) Introduction to Quantitative Genetics. New York, Longman Scientific and Technical
14. Freed W (1994): Glutamatergic mechanisms mediating stimulant and antipsychotic drug effects. Neurosci Biobehav Rev 18:111-120
15. Freed W, Weinberger D, Bing L, Wyatt RJ (1980): Neuropharmacologic studies of phencyclidine (PCP)-induced locomotor stimulation in mice. Neuropharmacology 23:175-181
16. Freed W, Crump S, Jeste D (1984): Genetic effects on PCP-induced stimulation in recombinant inbred strains of mice. Pharmacol Biochem Behav 21:159-162
17. Gora-Maslak G, McClearn G, Crabbe J, Phillips T, Belknap J, Plomin R (1991): Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology. Psychopharmacology 104:413-424
18. Grebb J, Shelton R, Freed W (1987): Ditiazem or verapamil prevent haloperidol-induced apomorphine sensitivity in mice. J Neural Transm 68:241-255
19. Javitt D, Zukin S (1991): Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry 148:1301-1308
20. Kornetsky C (1976): Hyporesponsivity of chronic schizophrenic patients to dextroamphetamine. Arch Gen Psychiatry 33:1425-1428
21. Lander ES, Kruglyak L (1995): Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nature Genet 11:241-247
22. Lander ES, Schork N (1994): Genetic dissection of complex traits. Science 265:2037-2048
23. Lipton MA (1970): The relevance of chemically induced psychoses to schizophrenia. In Efron DH (ed), Psychotomimetic Drugs, New York, Raven Press
24. Manly KF, Elliott RW (1991): RI manager, a microcomputer program for analysis of data from recombinant inbred strains. Mammalian Genome 1:123-126
25. Neumann P (1992): Inference in linkage of multifactorial traits using recombinant inbred strains of mice. Behav Genet 22:665-676
26. Oliverio A, Eleftheriou B, Bailey D (1973): Exploratory activity: Genetic analysis of its modification by scopolamine and amphetamine. Physiol Behav 10:893-899
27. Phillips T, Crabbe J, Metten P, Belknap J (1994): Localization of genes affecting alcohol drinking in mice. Alcoholism Clin Exp Res 18:931-941
28. Phillips TJ, Huson M, Gwiazdon C, Burkhart-Kasch S, Shen E (1995): Effects of acute and repeated ethanol exposures on the locomotor activity of BXD recombinant inbred mice. Alcohol Clin Exp Res 19:1-10
29. Plomin R, McClearn G (1993): Quantitative trait loci (QTL) analyses and alcohol related behaviors, Behav Genet 23:197-211
30. Plomin R, McClearn GE, Gora-Maslak G, Neiderhiser JM (1991): Use of recombinant inbred strains to detect quantitative trait loci associated with behavior. Behav Genet 21:99-116
31. Robinson T, Becker J (1986): Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychoses. Brain Res Rev 11:157-198
32. Sanberg PR, Hagenmayer SH, Henault M (1985): Automated measurement of multivariate locomotor behavior in rodents. Neurobehav Toxicol Teratol 7:87-94
33. Snyder S, Bannerjee S, Yamamura H, Greenberg D (1974): Drugs, neurotransmitters, and schizophrenia: Phenothiazines, amphetamine, and enzymes synthesizing psychotomimetic drugs and schizophrenia research. Science 184:1243-1253
34. Sokal R, Rohlf F (1981): Biometry, San Francisco, CA, Freeman, pp 779-782
35. Taylor B (1978): Recombinant inbred strains: Use in gene mapping. In Morse HC (ed), Origins of Inbred Mice. New York, Academic Press, pp 423-438