Conditional Control of Alternative Splicing through Light-Triggered Splice-Switching Oligonucleotides

Journal of the American Chemical Society

Volumn 137, Issue 10, 2015, Pages 3656-3662

  Hemphill, James ^a,b   Liu, Qingyang ^b   Uprety, Rajendra ^b   Samanta, Subhas ^a   Tsang, Michael ^c   Juliano, Rudolph L ^d   Deiters, Alexander ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; GENES; MACHINERY; MAMMALS; NUCLEIC ACIDS; OLIGONUCLEOTIDES; PROTEINS; RNA;

ALTERNATIVE SPLICING; CURRENT LIMITATION; GENETIC CONTROL; PRECISE CONTROL; PROTEIN CODING SEQUENCES; REGULATORY ELEMENTS; SPATIAL AND TEMPORAL RESOLUTIONS; TEMPORAL CONTROLS;

SWITCHING;

OLIGONUCLEOTIDE; SPLICE SWITCHING OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENE FUNCTION; GENE SEQUENCE; GENETIC REGULATION; LIGHT; NONHUMAN; REPORTER GENE; SIGNAL TRANSDUCTION; SPATIOTEMPORAL ANALYSIS; ULTRAVIOLET IRRADIATION; ULTRAVIOLET RADIATION; ZEBRA FISH; ANIMAL; CHEMISTRY; GENETICS; HELA CELL LINE; HUMAN; RADIATION RESPONSE;

ALTERNATIVE SPLICING; ANIMALS; HELA CELLS; HUMANS; LIGHT; OLIGONUCLEOTIDES; ZEBRAFISH;

EID: 84925251338     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b00580     Document Type: Article

References (44)

1. Scherrer, K.; Imaizumi-Scherrer, M. T.; Reynaud, C. A.; Therwath, A. Mol. Biol. Rep. 1979, 5, 5
2. Lamond, A. I. BioEssays 1993, 15, 595
3. Leff, S. E.; Rosenfeld, M. G.; Evans, R. M. Annu. Rev. Biochem. 1986, 55, 1091
4. Ozsolak, F.; Milos, P. M. Nat. Rev. Genet. 2011, 12, 87
5. Pan, Q.; Shai, O.; Lee, L. J.; Frey, B. J.; Blencowe, B. J. Nat. Genet. 2008, 40, 1413
6. Wang, E. T.; Sandberg, R.; Luo, S.; Khrebtukova, I.; Zhang, L.; Mayr, C.; Kingsmore, S. F.; Schroth, G. P.; Burge, C. B. Nature 2008, 456, 470
7. Cartegni, L.; Chew, S. L.; Krainer, A. R. Nat. Rev. Genet. 2002, 3, 285
8. Tazi, J.; Durand, S.; Jeanteur, P. Trends Biochem. Sci. 2005, 30, 469
9. Kole, R.; Krainer, A. R.; Altman, S. Nat. Rev. Drug Discovery 2012, 11, 125
10. Sazani, P.; Kole, R. Prog. Mol. Subcell. Biol. 2003, 31, 217
11. Sazani, P.; Kole, R. J. Clin. Invest. 2003, 112, 481
12. Sazani, P.; Kang, S. H.; Maier, M. A.; Wei, C.; Dillman, J.; Summerton, J.; Manoharan, M.; Kole, R. Nucleic Acids Res. 2001, 29, 3965
13. van Deutekom, J. C.; Janson, A. A.; Ginjaar, I. B.; Frankhuizen, W. S.; Aartsma-Rus, A.; Bremmer-Bout, M.; den Dunnen, J. T.; Koop, K.; van der Kooi, A. J.; Goemans, N. M.; de Kimpe, S. J.; Ekhart, P. F.; Venneker, E. H.; Platenburg, G. J.; Verschuuren, J. J.; van Ommen, G. J. N. Engl. J. Med. 2007, 357, 2677
14. Kinali, M.; Arechavala-Gomeza, V.; Feng, L.; Cirak, S.; Hunt, D.; Adkin, C.; Guglieri, M.; Ashton, E.; Abbs, S.; Nihoyannopoulos, P.; Garralda, M. E.; Rutherford, M.; McCulley, C.; Popplewell, L.; Graham, I. R.; Dickson, G.; Wood, M. J.; Wells, D. J.; Wilton, S. D.; Kole, R.; Straub, V.; Bushby, K.; Sewry, C.; Morgan, J. E.; Muntoni, F. Lancet Neurol. 2009, 8, 918
15. Goemans, N. M.; Tulinius, M.; van den Akker, J. T.; Burm, B. E.; Ekhart, P. F.; Heuvelmans, N.; Holling, T.; Janson, A. A.; Platenburg, G. J.; Sipkens, J. A.; Sitsen, J. M.; Aartsma-Rus, A.; van Ommen, G. J.; Buyse, G.; Darin, N.; Verschuuren, J. J.; Campion, G. V.; de Kimpe, S. J.; van Deutekom, J. C. N. Engl. J. Med. 2011, 364, 1513
16. Cirak, S.; Arechavala-Gomeza, V.; Guglieri, M.; Feng, L.; Torelli, S.; Anthony, K.; Abbs, S.; Garralda, M. E.; Bourke, J.; Wells, D. J.; Dickson, G.; Wood, M. J.; Wilton, S. D.; Straub, V.; Kole, R.; Shrewsbury, S. B.; Sewry, C.; Morgan, J. E.; Bushby, K.; Muntoni, F. Lancet 2011, 378, 595
17. Mendell, J. R.; Rodino-Klapac, L. R.; Sahenk, Z.; Roush, K.; Bird, L.; Lowes, L. P.; Alfano, L.; Gomez, A. M.; Lewis, S.; Kota, J.; Malik, V.; Shontz, K.; Walker, C. M.; Flanigan, K. M.; Corridore, M.; Kean, J. R.; Allen, H. D.; Shilling, C.; Melia, K. R.; Sazani, P.; Saoud, J. B.; Kaye, E. M.; Group, E. S. Ann. Neurol. 2013, 74, 637
18. Grabowski, P. Curr. Opin. Genet. Dev. 2011, 21, 388
19. Grabowski, P. J.; Black, D. L. Prog. Neurobiol. 2001, 65, 289
20. Goodwin, S. F.; Taylor, B. J.; Villella, A.; Foss, M.; Ryner, L. C.; Baker, B. S.; Hall, J. C. Genetics 2000, 154, 725
21. Strehler, E. E.; Zacharias, D. A. Physiol. Rev. 2001, 81, 21
22. Ott, E. B.; Te Velthuis, A. J.; Bagowski, C. P. Gene Expression Patterns 2007, 7, 620
23. Rissone, A.; Sangiorgio, L.; Monopoli, M.; Beltrame, M.; Zucchi, I.; Bussolino, F.; Arese, M.; Cotelli, F. Dev. Dyn. 2010, 239, 688
24. Mullen, G. P.; Rogalski, T. M.; Bush, J. A.; Gorji, P. R.; Moerman, D. G. Mol. Biol. Cell 1999, 10, 3205
25. Nilsen, T. W.; Graveley, B. R. Nature 2010, 463, 457
26. Liu, Q.; Deiters, A. Acc. Chem. Res. 2014, 47, 45
27. Brieke, C.; Rohrbach, F.; Gottschalk, A.; Mayer, G.; Heckel, A. Angew. Chem., Int. Ed. 2012, 51, 8446
28. Dominski, Z.; Kole, R. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 8673
29. Kotula, J. W.; Pratico, E. D.; Ming, X.; Nakagawa, O.; Juliano, R. L.; Sullenger, B. A. Nucleic Acid Ther. 2012, 22, 187
30. Ming, X.; Alam, M. R.; Fisher, M.; Yan, Y.; Chen, X.; Juliano, R. L. Nucleic Acids Res. 2010, 38, 6567
31. Nakagawa, O.; Ming, X.; Huang, L.; Juliano, R. L. J. Am. Chem. Soc. 2010, 132, 8848
32. Ming, X.; Carver, K.; Fisher, M.; Noel, R.; Cintrat, J. C.; Gillet, D.; Barbier, J.; Cao, C.; Bauman, J.; Juliano, R. L. Nucleic Acids Res. 2013, 41, 3673
33. Resina, S.; Kole, R.; Travo, A.; Lebleu, B.; Thierry, A. R. J. Gene Med. 2007, 9, 498
34. Connelly, C. M.; Uprety, R.; Hemphill, J.; Deiters, A. Mol. BioSyst. 2012, 8, 2987
35. Ordoukhanian, P.; Taylor, J. S. Bioconjugate Chem. 2000, 11, 94
36. Dong, Q.; Svoboda, K.; Tiersch, T.; Monroe, W. J. Photochem. Photobiol. B 2007, 88, 137
37. Holder, N.; Xu, Q. Methods Mol. Biol. 1999, 97, 487
38. Xu, Q. Methods Mol. Biol. 1999, 127, 125
39. Hu, S.; Wu, Z.; Yan, Y.; Li, Y. Acta Biochim. Biophys. Sin. 2011, 43, 387
40. Okuda, Y.; Ogura, E.; Kondoh, H.; Kamachi, Y. PLoS Genet. 2010, 6, e1000936
41. Okuda, Y.; Yoda, H.; Uchikawa, M.; Furutani-Seiki, M.; Takeda, H.; Kondoh, H.; Kamachi, Y. Dev. Dyn. 2006, 235, 811
42. Girard, F.; Crémazy, F.; Berta, P.; Renucci, A. Mech. Dev. 2001, 100, 71
43. Hu, S. N.; Yu, H.; Zhang, Y. B.; Wu, Z. L.; Yan, Y. C.; Li, Y. X.; Li, Y. Y.; Li, Y. P. FEBS Lett. 2012, 586, 222
44. Schneider, P. N.; Olthoff, J. T.; Matthews, A. J.; Houston, D. W. Genesis 2011, 49, 117