Bcl2 deficiency activates FoxO through Akt inactivation and accelerates osteoblast differentiation

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Moriishi, Takeshi ^a   Kawai, Yosuke ^a   Komori, Hisato ^a   Rokutanda, Satoshi ^a   Eguchi, Yutaka ^b   Tsujimoto, Yoshihide ^b   Asahina, Izumi ^a   Komori, Toshihisa ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; BROXURIDINE; FAS LIGAND; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45 ALPHA; MESSENGER RNA; OSTEOCALCIN; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; RINFABATE; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR FOXO4; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; FOXO3 PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIM GENE; CALVARIA; CELL DENSITY; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; FASL GENE; FOXO1 GENE; FOXO3A GENE; FOXO4 GENE; GADD45A GENE; GENE EXPRESSION; IGFBP3 GENE; IN VITRO STUDY; LONGEVITY; MOUSE; NICK END LABELING; NONHUMAN; OSTEOBLAST; P53 GENE; PROTEIN PHOSPHORYLATION; PTEN GENE; UPREGULATION; ANIMAL; BONE DEVELOPMENT; C57BL MOUSE; CYTOLOGY; GENE DELETION; GENETICS; METABOLISM;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; FORKHEAD TRANSCRIPTION FACTORS; GENE DELETION; MICE; MICE, INBRED C57BL; OSTEOBLASTS; OSTEOGENESIS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; UP-REGULATION;

EID: 84925224023     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086629     Document Type: Article

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