Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk

European Journal of Cancer

Volumn 50, Issue 18, 2014, Pages 3168-3177

  Llorca Cardeñosa, Marta J ^a   Peña Chilet, Maria ^a   Mayor, Matias ^b   Gomez Fernandez, Cristina ^b   Casado, Beatriz ^b   Martin Gonzalez, Manuel ^c   Carretero, Gregorio ^d   Lluch, Ana ^a   Martinez Cadenas, Conrado ^e   Ibarrola Villava, Maider ^a   Ribas, Gloria ^a  

^a Instituto Universitario IVI INCLIVA   (Spain)

^b HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^c HOSPITAL RAMÓN Y CAJAL   (Spain)

^d Departments of Immunology and Microbiology   (Spain)

^e UNIVERSITAT JAUME I   (Spain)

Author keywords

Case control study; Cutaneous melanoma; Susceptibility; Telomere length; TERT CLPTM1 locus

Indexed keywords

DNA; GENOMIC DNA; TELOMERASE REVERSE TRANSCRIPTASE; TELOMERIC REPEAT BINDING FACTOR 1; CLPTM1 PROTEIN, HUMAN; MEMBRANE PROTEIN; TELOMERASE;

ADULT; ARTICLE; CANCER RISK; CHILDHOOD INJURY; CLPTM1L GENE; CONTROLLED STUDY; CUTANEOUS MELANOMA; DNA EXTRACTION; FEMALE; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC RISK; GENOTYPE; HAPLOTYPE; HUMAN; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SUNBURN; TELOMERE; TELOMERE HOMEOSTASIS; CASE CONTROL STUDY; GENETIC PREDISPOSITION; GENETICS; MELANOMA; META ANALYSIS; MIDDLE AGED; RISK FACTOR; SKIN TUMOR;

ADULT; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MELANOMA; MEMBRANE PROTEINS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SKIN NEOPLASMS; TELOMERASE; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 1;

EID: 84925223931     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.09.017     Document Type: Article

References (41)

1. M.A. Blasco Mammalian telomeres and telomerase: why they matter for cancer and aging Eur J Cell Biol 82 9 2003 441 446
2. J.W. Szostak Telomerase: the beginning of the ends Nature 337 6205 1989 303 304
3. A. Smogorzewska, B. van Steensel, A. Bianchi, S. Oelmann, M.R. Schaefer, and G. Schnapp Control of human telomere length by TRF1 and TRF2 Mol Cell Biol 20 5 2000 1659 1668
4. B. van Steensel, and T. de Lange Control of telomere length by the human telomeric protein TRF1 Nature 385 6618 1997 740 743
5. T. Rafnar, P. Sulem, S.N. Stacey, F. Geller, J. Gudmundsson, and A. Sigurdsson Sequence variants at the TERT-CLPTM1L locus associate with many cancer types Nat Genet 41 2 2009 221 227
6. S.E. Bojesen, K.A. Pooley, S.E. Johnatty, J. Beesley, K. Michailidou, and J.P. Tyrer Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer Nat Genet 45 4 2013 371-84, 384e1-2
7. S. Horn, A. Figl, P.S. Rachakonda, C. Fischer, A. Sucker, and A. Gast TERT promoter mutations in familial and sporadic melanoma Science 339 6122 2013 959 961
8. F.W. Huang, E. Hodis, M.J. Xu, G.V. Kryukov, L. Chin, and L.A. Garraway Highly recurrent TERT promoter mutations in human melanoma Science 339 6122 2013 957 959
9. M.H. Law, G.W. Montgomery, K.M. Brown, N.G. Martin, G.J. Mann, and N.K. Hayward Meta-analysis combining new and existing data sets confirms that the TERT-CLPTM1L locus influences melanoma risk J Invest Dermatol 132 2 2012 485 487
10. C. Li, Z. Yin, W. Wu, X. Li, and B. Zhou Genetic variants in TERT-CLPTM1L genetic region associated with several types of cancer: a meta-analysis Gene 526 2 2013 390 399
11. J. Yin, Y. Li, M. Yin, J. Sun, L. Liu, and Q. Qin TERT-CLPTM1L polymorphism rs401681 contributes to cancers risk: evidence from a meta-analysis based on 29 publications PLoS One 7 11 2012 e50650
12. C. Bodelon, R.M. Pfeiffer, V. Bollati, J. Debbache, D. Calista, and P. Ghiorzo On the interplay of telomeres, nevi and the risk of melanoma PLoS One 7 12 2012 e52466
13. L.S. Burke, P.L. Hyland, R.M. Pfeiffer, J. Prescott, W. Wheeler, and L. Mirabello Telomere length and the risk of cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations PLoS One 8 8 2013 e71121
14. J. Han, A.A. Qureshi, J. Prescott, Q. Guo, L. Ye, and D.J. Hunter A prospective study of telomere length and the risk of skin cancer J Invest Dermatol 129 2 2009 415 421
15. H. Ma, Z. Zhou, S. Wei, Z. Liu, K.A. Pooley, and A.M. Dunning Shortened telomere length is associated with increased risk of cancer: a meta-analysis PLoS One 6 6 2011 e20466
16. H. Nan, M. Du, I. De Vivo, J.E. Manson, S. Liu, and A. McTiernan Shorter telomeres associate with a reduced risk of melanoma development Cancer Res 71 21 2011 6758 6763
17. H. Nan, A.A. Qureshi, J. Prescott, I. De Vivo, and J. Han Genetic variants in telomere-maintaining genes and skin cancer risk Hum Genet 129 3 2011 247 253
18. I.M. Wentzensen, L. Mirabello, R.M. Pfeiffer, and S.A. Savage The association of telomere length and cancer: a meta-analysis Cancer Epidemiol Biomarkers Prev 20 6 2011 1238 1250
19. P. Willeit, J. Willeit, A. Kloss-Brandstatter, F. Kronenberg, and S. Kiechl Fifteen-year follow-up of association between telomere length and incident cancer and cancer mortality JAMA 306 1 2011 42 44
20. P. Willeit, J. Willeit, A. Mayr, S. Weger, F. Oberhollenzer, and A. Brandstatter Telomere length and risk of incident cancer and cancer mortality JAMA 304 1 2010 69 75
21. M. Berwick, and C. Wiggins The current epidemiology of cutaneous malignant melanoma Front Biosci 11 2006 1244 1254
22. A.F. Jerant, J.T. Johnson, C.D. Sheridan, and T.J. Caffrey Early detection and treatment of skin cancer Am Fam Physician 62 2 2000 357-68, 375-6, 381-2
23. J.L. Rees Melanoma: what are the gaps in our knowledge PLoS Med 5 6 2008 e122
24. M.A. Tucker, and A.M. Goldstein Melanoma etiology: where are we? Oncogene 22 20 2003 3042 3052
25. C. Michaloglou, L.C. Vredeveld, M.S. Soengas, C. Denoyelle, T. Kuilman, and C.M. van der Horst BRAFE600-associated senescence-like cell cycle arrest of human naevi Nature 436 7051 2005 720 724
26. M.T. Bastiaens, J.A. ter Huurne, C. Kielich, N.A. Gruis, R.G. Westendorp, and B.J. Vermeer Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair Am J Hum Genet 68 4 2001 884 894
27. V. Bataille, J.A. Bishop, P. Sasieni, A.J. Swerdlow, E. Pinney, and K. Griffiths Risk of cutaneous melanoma in relation to the numbers, types and sites of naevi: a case-control study Br J Cancer 73 12 1996 1605 1611
28. H. Laayouni, F. Calafell, and J. Bertranpetit A genome-wide survey does not show the genetic distinctiveness of Basques Hum Genet 127 4 2010 455 458
29. S.N. Stacey, P. Sulem, G. Masson, S.A. Gudjonsson, G. Thorleifsson, and M. Jakobsdottir New common variants affecting susceptibility to basal cell carcinoma Nat Genet 41 8 2009 909 914
30. M. Pena-Chilet, M. Blanquer-Maceiras, M. Ibarrola-Villava, C. Martinez-Cadenas, M. Martin-Gonzalez, and C. Gomez-Fernandez Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population BMC Cancer 13 2013 160
31. R.M. Cawthon Telomere measurement by quantitative PCR Nucleic Acids Res 30 10 2002 e47
32. B. Martinez-Delgado, K. Yanowsky, L. Inglada-Perez, S. Domingo, M. Urioste, and A. Osorio Genetic anticipation is associated with telomere shortening in hereditary breast cancer PLoS Genet 7 7 2011 e1002182
33. V. Bataille, B.S. Kato, M. Falchi, J. Gardner, M. Kimura, and M. Lens Nevus size and number are associated with telomere length and represent potential markers of a decreased senescence in vivo Cancer Epidemiol Biomarkers Prev 16 7 2007 1499 1502
34. D.M. Feldser, and C.W. Greider Short telomeres limit tumor progression in vivo by inducing senescence Cancer Cell 11 5 2007 461 469
35. D.C. Whiteman, C.A. Whiteman, and A.C. Green Childhood sun exposure as a risk factor for melanoma: a systematic review of epidemiologic studies Cancer Causes Control 12 1 2001 69 82
36. W.J. Mooi, and D.S. Peeper Oncogene-induced cell senescence-halting on the road to cancer N Engl J Med 355 10 2006 1037 1046
37. V. Codd, C.P. Nelson, E. Albrecht, M. Mangino, J. Deelen, and J.L. Buxton Identification of seven loci affecting mean telomere length and their association with disease Nat Genet 45 4 2013 422-7, 427e1-2
38. L. Mirabello, K. Yu, P. Kraft, I. De Vivo, D.J. Hunter, and J. Prescott The association of telomere length and genetic variation in telomere biology genes Hum Mutat 31 9 2010 1050 1058
39. K.A. Pooley, J. Tyrer, M. Shah, K.E. Driver, J. Leyland, and J. Brown No association between TERT-CLPTM1L single nucleotide polymorphism rs401681 and mean telomere length or cancer risk Cancer Epidemiol Biomarkers Prev 19 7 2010 1862 1865
40. P. Grabowski, M. Hultdin, K. Karlsson, G. Tobin, A. Aleskog, and U. Thunberg Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status Blood 105 12 2005 4807 4812
41. U. Friedrich, E. Griese, M. Schwab, P. Fritz, K. Thon, and U. Klotz Telomere length in different tissues of elderly patients Mech Ageing Dev 119 3 2000 89 99