A genome-wide survey does not show the genetic distinctiveness of Basques

Human Genetics

Volumn 127, Issue 4, 2010, Pages 455-458

  Laayouni, Hafid ^a,b   Calafell, Francesc ^a,b   Bertranpetit, Jaume ^a,b  

^a INSTITUTE OF EVOLUTIONARY BIOLOGY CSIC UNIVERSITAT POMPEU FABRA   (Spain)

^b CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN; MITOCHONDRIAL DNA; RHESUS ANTIGEN;

ARTICLE; BLOOD GROUP ABO SYSTEM; ETHNIC GROUP; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC DIFFERENCE; GENETIC POLYMORPHISM; GENETIC SIMILARITY; GENOTYPE; GEOGRAPHIC DISTRIBUTION; HLA SYSTEM; HUMAN; IBERIAN; POPULATION RESEARCH; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SPANISH;

ALLELES; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; GENETICS, POPULATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PRINCIPAL COMPONENT ANALYSIS; SPAIN;

EID: 77952097493     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-010-0798-3     Document Type: Article

References (21)

1. A Achilli C Rengo C Magri V Battaglia A Olivieri R Scozzari F Cruciani M Zeviani E Briem V Carelli P Moral JM Dugoujon U Roostalu EL Loogvali T Kivisild HJ Bandelt M Richards R Villems AS Santachiara-Benerecetti O Semino A Torroni 2004 The molecular dissection of mtDNA haplogroup H confirms that the Franco-Cantabrian glacial refuge was a major source for the European gene pool Am J Hum Genet 75 910 918 10.1086/425590 1:CAS:528:DC%2BD2cXptVSnsLY%3D 15382008 (Pubitemid 39390500)
2. SM Adams E Bosch PL Balaresque SJ Ballereau AC Lee E Arroyo AM López-Parra M Aler MS Grifo M Brion A Carracedo J Lavinha B Martínez-Jarreta L Quintana-Murci A Picornell M Ramon K Skorecki DM Behar F Calafell MA Jobling 2008 The genetic legacy of religious diversity and intolerance: paternal lineages of Christians, Jews and Muslims in the Iberian Peninsula Am J Hum Genet 83 725 736 10.1016/j.ajhg.2008.11.007 1:CAS:528:DC%2BD1MXit1Gq 19061982
3. F Bauduer J Feingold D Lacombe 2005 The Basques: review of population genetics and Mendelian disorders Hum Biol 77 5 619 637 10.1353/hub.2006.0001 16596943 (Pubitemid 43375843)
4. Bertranpetit J, Cavalli-Sforza LL (1991) A genetic reconstruction of the history of the population of the Iberian Peninsula. Ann Hum Genet 55:51-67
5. J Bertranpetit J Sala F Calafell PA Underhill P Moral D Comas 1995 Human mitochondrial DNA variation and the origin of Basques Ann Hum Genet 59 63 81 10.1111/j.1469-1809.1995.tb01606.x 1:STN:280:DyaK2M3otlagug%3D%3D 7762985
6. E Bosch F Calafell A Pérez-Lezaun D Comas E Mateu J Bertranpetit 1997 Population history of north Africa: evidence from classical genetic markers Hum Biol 69 295 311 1:STN:280:DyaK2szgs1OqsA%3D%3D 9164042 (Pubitemid 27195660)
7. E Bosch F Calafell D Comas PJ Oefner PA Underhill J Bertranpetit 2001 High-resolution analysis of human Y-chromosome variation shows a sharp discontinuity and limited gene flow between northwestern Africa and the Iberian Peninsula Am J Hum Genet 68 1019 1029 10.1086/319521 1:CAS:528: DC%2BD3MXkvFarsL4%3D 11254456 (Pubitemid 32289745)
8. F Calafell J Bertranpetit 1994 Mountains and genes: population history of the Pyrenees Hum Biol 66 823 842 1:STN:280:DyaK2M%2FpsFWqsQ%3D%3D 8001912 (Pubitemid 2159908)
9. F Calafell J Bertranpetit 1994 Principal component analysis of gene frequencies and the origin of Basques Am J Phys Anthropol 93 201 215 10.1002/ajpa.1330930205 1:STN:280:DyaK2c7pslansg%3D%3D 8147436 (Pubitemid 24055997)
10. JN Chalmers EW Ikin AE Mourant 1949 The ABO, MN and Rh blood groups of the Basque people Am J Phys Anthropol 7 529 544 10.1002/ajpa.1330070405 1:STN:280:DyaG3c%2FhsVequg%3D%3D 15404766
11. P Garagnani H Laayouni A Gonzalez-Neira M Sikora D Luiselli J Bertranpetit F Calafell 2009 Isolated populations as treasure troves in genetic epidemiology: the case of the Basques Eur J Hum Genet 17 1490 1494 10.1038/ejhg.2009.69 19417765
12. Lao O, Lu TT, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Rüther A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Krawczak M, Kayser M (2008) Correlation between genetic and geographic structure in Europe. Curr Biol 18:1241-1248
13. JZ Li DM Absher H Tang AM Southwick AM Casto S Ramachandran HM Cann GS Barsh M Feldman LL Cavalli-Sforza RM Myers 2008 Worldwide human relationships inferred from genome-wide patterns of variation Science 319 1100 1104 10.1126/science.1153717 1:CAS:528:DC%2BD1cXit1yhsbc%3D 18292342 (Pubitemid 351300793)
14. J Novembre T Johnson K Bryc Z Kutalik AR Boyko A Auton A Indap KS King S Bergmann MR Nelson M Stephens CD Bustamante 2008 Genes mirror geography within Europe Nature 456 98 101 10.1038/nature07331 1:CAS:528:DC%2BD1cXhtlCjtrjM 18758442
15. N Patterson AL Price D Reich 2006 Population structure and eigen analysis PLoS Genet 2 e190 10.1371/journal.pgen.0020190 17194218 (Pubitemid 46045188)
16. JV Pearson MJ Huentelman RF Halperin WD Tembe S Melquist N Homer M Brun S Szelinger KD Coon VL Zismann JA Webster T Beach SB Sando JO Aasly R Heun F Jessen H Kolsch M Tsolaki M Daniilidou EM Reiman A Papassotiropoulos ML Hutton DA Stephan DW Craig 2007 Identification of the genetic basis for complex disorders by use of pooling-based genome wide single-nucleotide-polymorphism association studies Am J Hum Genet 80 126 139 10.1086/510686 1:CAS:528:DC%2BD2sXms1Cmtw%3D%3D 17160900 (Pubitemid 46047656)
17. ZH Rosser T Zerjal ME Hurles M Adojaan D Alavantic A Amorim W Amos M Armenteros E Arroyo G Barbujani G Beckman L Beckman J Bertranpetit E Bosch DG Bradley G Brede G Cooper HB Corte-Real P de Knijff R Decorte YE Dubrova O Evgrafov A Gilissen S Glisic M Golge EW Hill A Jeziorowska L Kalaydjieva M Kayser T Kivisild SA Kravchenko A Krumina V Kucinskas J Lavinha LA Livshits P Malaspina S Maria K McElreavey TA Meitinger AV Mikelsaar RJ Mitchell K Nafa J Nicholson S Norby A Pandya J Parik PC Patsalis L Pereira B Peterlin G Pielberg MJ Prata C Previdere L Roewer S Rootsi DC Rubinsztein J Saillard FR Santos G Stefanescu BC Sykes A Tolun R Villems C Tyler-Smith MA Jobling 2000 Y-chromosomal diversity in Europe is clinal and influenced primarily by geography, rather than by language Am J Hum Genet 67 1526 1543 10.1086/316890 1:STN:280:DC%2BD3M%2Fos1Whtw%3D%3D 11078479
18. A Salas D Comas MV Lareu J Bertranpetit A Carracedo 1998 mtDNA analysis of the Galician population: a genetic edge of European variation Eur J Hum Genet 6 365 375 10.1038/sj.ejhg.5200202 1:CAS:528:DyaK1MXhsFGku7s%3D 9781045 (Pubitemid 28395799)
19. W Stacklies H Redestig M Scholz D Walther J Selbig 2007 pcaMethods-a bioconductor package providing PCA methods for incomplete data Bioinformatics 23 1164 1167 10.1093/bioinformatics/btm069 1:CAS:528:DC%2BD2sXmtVKqu7g%3D 17344241 (Pubitemid 47050571)
20. BS Weir CC Cockerham 1984 Estimating F-statistics for the analysis of population structure Evolution 38 1358 1370 10.2307/2408641
21. M Zlojutro R Roy J Palikij MH Crawford 2006 Autosomal STR variation in a Basque population: Vizcaya Province Hum Biol 78 599 618 10.1353/hub.2007.0007 1:STN:280:DC%2BD2s3psFOisQ%3D%3D 17506289 (Pubitemid 46648440)