메뉴 건너뛰기




Volumn 125, Issue 11, 2015, Pages 1782-1792

Acetylation of C/EBPε is a prerequisite for terminal neutrophil differentiation

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; CCAAT ENHANCER BINDING PROTEIN EPSILON; CD34 ANTIGEN; COLLAGENASE; DNA; E1A ASSOCIATED P300 PROTEIN; LACTOFERRIN; SIRTUIN 1; CCAAT ENHANCER BINDING PROTEIN; CEBPE PROTEIN, HUMAN; HISTONE ACETYLTRANSFERASE PCAF; HYBRID PROTEIN; LTF PROTEIN, HUMAN; LYSINE; P300-CBP-ASSOCIATED FACTOR; SIRT1 PROTEIN, HUMAN;

EID: 84925014722     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-12-543850     Document Type: Article
Times cited : (34)

References (45)
  • 1
    • 0034624828 scopus 로고    scopus 로고
    • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
    • Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature. 2000;404(6774):193-197.
    • (2000) Nature , vol.404 , Issue.6774 , pp. 193-197
    • Akashi, K.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4
  • 2
    • 0028534860 scopus 로고
    • The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
    • Morrison SJ, Weissman IL. The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity. 1994;1(8):661-673.
    • (1994) Immunity , vol.1 , Issue.8 , pp. 661-673
    • Morrison, S.J.1    Weissman, I.L.2
  • 3
    • 47049090395 scopus 로고    scopus 로고
    • Lessons from congenital neutropenia: 50 Years of progress in understanding myelopoiesis
    • Berliner N. Lessons from congenital neutropenia: 50 years of progress in understanding myelopoiesis. Blood. 2008;111(12):5427-5432.
    • (2008) Blood , vol.111 , Issue.12 , pp. 5427-5432
    • Berliner, N.1
  • 4
    • 0035480007 scopus 로고    scopus 로고
    • Hematopoietic development: A balancing act
    • Cantor AB, Orkin SH. Hematopoietic development: a balancing act. Curr Opin Genet Dev. 2001;11(5):513-519.
    • (2001) Curr Opin Genet Dev , vol.11 , Issue.5 , pp. 513-519
    • Cantor, A.B.1    Orkin, S.H.2
  • 5
    • 0032527272 scopus 로고    scopus 로고
    • Do stem cells play dice?
    • discussion 352
    • Enver T, Heyworth CM, Dexter TM. Do stem cells play dice? Blood. 1998;92(2):348-351, discussion 352.
    • (1998) Blood , vol.92 , Issue.2 , pp. 348-351
    • Enver, T.1    Heyworth, C.M.2    Dexter, T.M.3
  • 6
    • 0032528354 scopus 로고    scopus 로고
    • Lineage commitment and maturation in hematopoietic cells: The case for extrinsic regulation
    • discussion 352
    • Metcalf D. Lineage commitment and maturation in hematopoietic cells: the case for extrinsic regulation. Blood. 1998;92(2):345-347, discussion 352.
    • (1998) Blood , vol.92 , Issue.2 , pp. 345-347
    • Metcalf, D.1
  • 7
    • 38349157811 scopus 로고    scopus 로고
    • Hematopoietic cytokines
    • Metcalf D. Hematopoietic cytokines. Blood. 2008;111(2):485-491.
    • (2008) Blood , vol.111 , Issue.2 , pp. 485-491
    • Metcalf, D.1
  • 8
    • 0031029557 scopus 로고    scopus 로고
    • Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice
    • Zhang DE, Zhang P, Wang ND, Hetherington CJ, Darlington GJ, Tenen DG. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Natl Acad Sci USA. 1997;94(2):569-574.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.2 , pp. 569-574
    • Zhang, D.E.1    Zhang, P.2    Wang, N.D.3    Hetherington, C.J.4    Darlington, G.J.5    Tenen, D.G.6
  • 9
    • 35348875999 scopus 로고    scopus 로고
    • Transcriptional control of granulocyte and monocyte development
    • Friedman AD. Transcriptional control of granulocyte and monocyte development. Oncogene. 2007;26(47):6816-6828.
    • (2007) Oncogene , vol.26 , Issue.47 , pp. 6816-6828
    • Friedman, A.D.1
  • 10
    • 0242720667 scopus 로고    scopus 로고
    • Regulation of granulocyte and monocyte differentiation by CCAAT/enhancer binding protein alpha
    • Friedman AD, Keefer JR, Kummalue T, Liu H, Wang QF, Cleaves R. Regulation of granulocyte and monocyte differentiation by CCAAT/enhancer binding protein alpha. Blood Cells Mol Dis. 2003;31(3):338-341.
    • (2003) Blood Cells Mol Dis , vol.31 , Issue.3 , pp. 338-341
    • Friedman, A.D.1    Keefer, J.R.2    Kummalue, T.3    Liu, H.4    Wang, Q.F.5    Cleaves, R.6
  • 11
    • 0035102650 scopus 로고    scopus 로고
    • The role of C/EBP(epsilon) in the terminal stages of granulocyte differentiation
    • Lekstrom-Himes JA. The role of C/EBP(epsilon) in the terminal stages of granulocyte differentiation. Stem Cells. 2001;19(2):125-133.
    • (2001) Stem Cells , vol.19 , Issue.2 , pp. 125-133
    • Lekstrom-Himes, J.A.1
  • 12
    • 0030659176 scopus 로고    scopus 로고
    • Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice
    • Yamanaka R, Barlow C, Lekstrom-Himes J, et al. Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice. Proc Natl Acad Sci USA. 1997;94(24):13187-13192.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.24 , pp. 13187-13192
    • Yamanaka, R.1    Barlow, C.2    Lekstrom-Himes, J.3
  • 13
  • 14
    • 0030865680 scopus 로고    scopus 로고
    • A novel, myeloid transcription factor, C/EBP epsilon, is upregulated during granulocytic, but not monocytic, differentiation
    • Morosetti R, Park DJ, Chumakov AM, et al. A novel, myeloid transcription factor, C/EBP epsilon, is upregulated during granulocytic, but not monocytic, differentiation. Blood. 1997;90(7):2591-2600.
    • (1997) Blood , vol.90 , Issue.7 , pp. 2591-2600
    • Morosetti, R.1    Park, D.J.2    Chumakov, A.M.3
  • 15
    • 0037944062 scopus 로고    scopus 로고
    • Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBP epsilon and PU.1
    • Gombart AF, Kwok SH, Anderson KL, Yamaguchi Y, Torbett BE, Koeffler HP. Regulation of neutrophil and eosinophil secondary granule gene expression by transcription factors C/EBP epsilon and PU.1. Blood. 2003;101(8):3265-3273.
    • (2003) Blood , vol.101 , Issue.8 , pp. 3265-3273
    • Gombart, A.F.1    Kwok, S.H.2    Anderson, K.L.3    Yamaguchi, Y.4    Torbett, B.E.5    Koeffler, H.P.6
  • 16
    • 33744940565 scopus 로고    scopus 로고
    • N-terminal region of CCAAT/enhancer-binding protein epsilon is critical for cell cycle arrest, apoptosis, and functional maturation during myeloid differentiation
    • Nakajima H, Watanabe N, Shibata F, Kitamura T, Ikeda Y, Handa M. N-terminal region of CCAAT/enhancer-binding protein epsilon is critical for cell cycle arrest, apoptosis, and functional maturation during myeloid differentiation. J Biol Chem. 2006;281(20):14494-14502.
    • (2006) J Biol Chem , vol.281 , Issue.20 , pp. 14494-14502
    • Nakajima, H.1    Watanabe, N.2    Shibata, F.3    Kitamura, T.4    Ikeda, Y.5    Handa, M.6
  • 17
    • 0035353169 scopus 로고    scopus 로고
    • Neutrophil-specific granule deficiency: Homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein - Epsilon
    • Gombart AF, Shiohara M, Kwok SH, Agematsu K, Komiyama A, Koeffler HP. Neutrophil-specific granule deficiency: homozygous recessive inheritance of a frameshift mutation in the gene encoding transcription factor CCAAT/enhancer binding protein - epsilon. Blood. 2001;97(9):2561-2567.
    • (2001) Blood , vol.97 , Issue.9 , pp. 2561-2567
    • Gombart, A.F.1    Shiohara, M.2    Kwok, S.H.3    Agematsu, K.4    Komiyama, A.5    Koeffler, H.P.6
  • 18
    • 27644496428 scopus 로고    scopus 로고
    • Aberrant expression of neutrophil and macrophage-related genes in a murine model for human neutrophil-specific granule deficiency
    • Gombart AF, Krug U, O'Kelly J, An E, Vegesna V, Koeffler HP. Aberrant expression of neutrophil and macrophage-related genes in a murine model for human neutrophil-specific granule deficiency. J Leukoc Biol. 2005;78(5):1153-1165.
    • (2005) J Leukoc Biol , vol.78 , Issue.5 , pp. 1153-1165
    • Gombart, A.F.1    Krug, U.2    O'Kelly, J.3    An, E.4    Vegesna, V.5    Koeffler, H.P.6
  • 19
    • 0033532546 scopus 로고    scopus 로고
    • Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilon
    • Lekstrom-Himes JA, Dorman SE, Kopar P, Holland SM, Gallin JI. Neutrophil-specific granule deficiency results from a novel mutation with loss of function of the transcription factor CCAAT/enhancer binding protein epsilon. J Exp Med. 1999;189(11):1847-1852.
    • (1999) J Exp Med , vol.189 , Issue.11 , pp. 1847-1852
    • Lekstrom-Himes, J.A.1    Dorman, S.E.2    Kopar, P.3    Holland, S.M.4    Gallin, J.I.5
  • 20
    • 58849093683 scopus 로고    scopus 로고
    • Human C/EBP-epsilon activator and repressor isoforms differentially reprogram myeloid lineage commitment and differentiation
    • Bedi R, Du J, Sharma AK, Gomes I, Ackerman SJ. Human C/EBP-epsilon activator and repressor isoforms differentially reprogram myeloid lineage commitment and differentiation. Blood. 2009;113(2):317-327.
    • (2009) Blood , vol.113 , Issue.2 , pp. 317-327
    • Bedi, R.1    Du, J.2    Sharma, A.K.3    Gomes, I.4    Ackerman, S.J.5
  • 21
    • 0032511054 scopus 로고    scopus 로고
    • Identification of transcriptional activation and repression domains in human CCAAT/enhancer-binding protein epsilon
    • Williamson EA, Xu HN, Gombart AF, et al. Identification of transcriptional activation and repression domains in human CCAAT/enhancer-binding protein epsilon. J Biol Chem. 1998;273(24):14796-14804.
    • (1998) J Biol Chem , vol.273 , Issue.24 , pp. 14796-14804
    • Williamson, E.A.1    Xu, H.N.2    Gombart, A.F.3
  • 22
    • 0031008479 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing
    • Yamanaka R, Kim GD, Radomska HS, et al. CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing. Proc Natl Acad Sci USA. 1997;94(12):6462-6467.
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.12 , pp. 6462-6467
    • Yamanaka, R.1    Kim, G.D.2    Radomska, H.S.3
  • 23
    • 0035947662 scopus 로고    scopus 로고
    • Structural and functional studies of CCAAT/enhancer-binding protein epsilon
    • Tang JG, Koeffler HP. Structural and functional studies of CCAAT/enhancer-binding protein epsilon. J Biol Chem. 2001;276(21):17739-17746.
    • (2001) J Biol Chem , vol.276 , Issue.21 , pp. 17739-17746
    • Tang, J.G.1    Koeffler, H.P.2
  • 24
    • 41549153181 scopus 로고    scopus 로고
    • C/EBPs: Recipients of extracellular signals through proteome modulation
    • Nerlov C. C/EBPs: recipients of extracellular signals through proteome modulation. Curr Opin Cell Biol. 2008;20(2):180-185.
    • (2008) Curr Opin Cell Biol , vol.20 , Issue.2 , pp. 180-185
    • Nerlov, C.1
  • 25
    • 33847724385 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein (C/EBP) beta is acetylated at multiple lysines: Acetylation of C/EBPbeta at lysine 39 modulates its ability to activate transcription
    • Ceseña TI, Cardinaux JR, Kwok R, Schwartz J. CCAAT/enhancer-binding protein (C/EBP) beta is acetylated at multiple lysines: acetylation of C/EBPbeta at lysine 39 modulates its ability to activate transcription. J Biol Chem. 2007;282(2):956-967.
    • (2007) J Biol Chem , vol.282 , Issue.2 , pp. 956-967
    • Ceseña, T.I.1    Cardinaux, J.R.2    Kwok, R.3    Schwartz, J.4
  • 26
    • 45049086596 scopus 로고    scopus 로고
    • Acetylation and deacetylation regulate CCAAT/enhancer binding protein beta at K39 in mediating gene transcription
    • Ceseña TI, Cui TX, Subramanian L, et al. Acetylation and deacetylation regulate CCAAT/enhancer binding protein beta at K39 in mediating gene transcription. Mol Cell Endocrinol. 2008;289(1-2):94-101.
    • (2008) Mol Cell Endocrinol , vol.289 , Issue.1-2 , pp. 94-101
    • Ceseña, T.I.1    Cui, T.X.2    Subramanian, L.3
  • 27
    • 33847284069 scopus 로고    scopus 로고
    • Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5
    • Wiper-Bergeron N, Salem HA, Tomlinson JJ, Wu D, Haché RJ. Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5. Proc Natl Acad Sci USA. 2007;104(8):2703-2708.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.8 , pp. 2703-2708
    • Wiper-Bergeron, N.1    Salem, H.A.2    Tomlinson, J.J.3    Wu, D.4    Haché, R.J.5
  • 28
    • 18544381583 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein epsilon: Changes in function upon phosphorylation by p38 MAP kinase
    • Williamson EA, Williamson IK, Chumakov AM, Friedman AD, Koeffler HP. CCAAT/enhancer binding protein epsilon: changes in function upon phosphorylation by p38 MAP kinase. Blood. 2005;105(10):3841-3847.
    • (2005) Blood , vol.105 , Issue.10 , pp. 3841-3847
    • Williamson, E.A.1    Williamson, I.K.2    Chumakov, A.M.3    Friedman, A.D.4    Koeffler, H.P.5
  • 29
    • 34248367421 scopus 로고    scopus 로고
    • Modulation of DNA binding properties of CCAAT/enhancer binding protein epsilon by heterodimer formation and interactions with NFkappaB pathway
    • Chumakov AM, Silla A, Williamson EA, Koeffler HP. Modulation of DNA binding properties of CCAAT/enhancer binding protein epsilon by heterodimer formation and interactions with NFkappaB pathway. Blood. 2007;109(10):4209-4219.
    • (2007) Blood , vol.109 , Issue.10 , pp. 4209-4219
    • Chumakov, A.M.1    Silla, A.2    Williamson, E.A.3    Koeffler, H.P.4
  • 30
    • 0033548255 scopus 로고    scopus 로고
    • A short conserved motif is required for repressor domain function in the myeloid-specific transcription factor CCAAT/enhancer-binding protein epsilon
    • Angerer ND, Du Y, Nalbant D, Williams SC. A short conserved motif is required for repressor domain function in the myeloid-specific transcription factor CCAAT/enhancer-binding protein epsilon. J Biol Chem. 1999;274(7):4147-4154.
    • (1999) J Biol Chem , vol.274 , Issue.7 , pp. 4147-4154
    • Angerer, N.D.1    Du, Y.2    Nalbant, D.3    Williams, S.C.4
  • 31
    • 16844383382 scopus 로고    scopus 로고
    • Repression and coactivation of CCAAT/enhancer-binding protein epsilon by sumoylation and protein inhibitor of activated STATx proteins
    • Kim J, Sharma S, Li Y, Cobos E, Palvimo JJ, Williams SC. Repression and coactivation of CCAAT/enhancer-binding protein epsilon by sumoylation and protein inhibitor of activated STATx proteins. J Biol Chem. 2005;280(13):12246-12254.
    • (2005) J Biol Chem , vol.280 , Issue.13 , pp. 12246-12254
    • Kim, J.1    Sharma, S.2    Li, Y.3    Cobos, E.4    Palvimo, J.J.5    Williams, S.C.6
  • 32
    • 84865963692 scopus 로고    scopus 로고
    • C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice
    • Kyme P, Thoennissen NH, Tseng CW, et al. C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice. J Clin Invest. 2012;122(9):3316-3329.
    • (2012) J Clin Invest , vol.122 , Issue.9 , pp. 3316-3329
    • Kyme, P.1    Thoennissen, N.H.2    Tseng, C.W.3
  • 34
    • 0033231036 scopus 로고    scopus 로고
    • Myeloid transcription factor C/EBPepsilon is involved in the positive regulation of lactoferrin gene expression in neutrophils
    • Verbeek W, Lekstrom-Himes J, Park DJ, et al. Myeloid transcription factor C/EBPepsilon is involved in the positive regulation of lactoferrin gene expression in neutrophils. Blood. 1999;94(9):3141-3150.
    • (1999) Blood , vol.94 , Issue.9 , pp. 3141-3150
    • Verbeek, W.1    Lekstrom-Himes, J.2    Park, D.J.3
  • 35
    • 77954465952 scopus 로고    scopus 로고
    • Histone deacetylase inhibition modulates cell fate decisions during myeloid differentiation
    • Bartels M, Geest CR, Bierings M, Buitenhuis M, Coffer PJ. Histone deacetylase inhibition modulates cell fate decisions during myeloid differentiation. Haematologica. 2010;95(7):1052-1060.
    • (2010) Haematologica , vol.95 , Issue.7 , pp. 1052-1060
    • Bartels, M.1    Geest, C.R.2    Bierings, M.3    Buitenhuis, M.4    Coffer, P.J.5
  • 36
    • 70350727161 scopus 로고    scopus 로고
    • Tight control of MEK-ERK activation is essential in regulating proliferation, survival, and cytokine production of CD34+-derived neutrophil progenitors
    • Geest CR, Buitenhuis M, Groot Koerkamp MJ, Holstege FC, Vellenga E, Coffer PJ. Tight control of MEK-ERK activation is essential in regulating proliferation, survival, and cytokine production of CD34+-derived neutrophil progenitors. Blood. 2009;114(16):3402-3412.
    • (2009) Blood , vol.114 , Issue.16 , pp. 3402-3412
    • Geest, C.R.1    Buitenhuis, M.2    Groot Koerkamp, M.J.3    Holstege, F.C.4    Vellenga, E.5    Coffer, P.J.6
  • 37
    • 84882592280 scopus 로고    scopus 로고
    • Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity
    • van Loosdregt J, Fleskens V, Fu J, et al. Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity. Immunity. 2013;39(2):259-271.
    • (2013) Immunity , vol.39 , Issue.2 , pp. 259-271
    • Van Loosdregt, J.1    Fleskens, V.2    Fu, J.3
  • 38
    • 84882692382 scopus 로고    scopus 로고
    • Canonical Wnt signaling negatively modulates regulatory T cell function
    • van Loosdregt J, Fleskens V, Tiemessen MM, et al. Canonical Wnt signaling negatively modulates regulatory T cell function. Immunity. 2013;39(2):298-310.
    • (2013) Immunity , vol.39 , Issue.2 , pp. 298-310
    • Van Loosdregt, J.1    Fleskens, V.2    Tiemessen, M.M.3
  • 39
    • 0032694990 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment
    • Park DJ, Chumakov AM, Vuong PT, et al. CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment. J Clin Invest. 1999;103(10):1399-1408.
    • (1999) J Clin Invest , vol.103 , Issue.10 , pp. 1399-1408
    • Park, D.J.1    Chumakov, A.M.2    Vuong, P.T.3
  • 40
    • 0032577070 scopus 로고    scopus 로고
    • C/EBPepsilon is a myeloid-specific activator of cytokine, chemokine, and macrophage-colony-stimulating factor receptor genes
    • Williams SC, Du Y, Schwartz RC, et al. C/EBPepsilon is a myeloid-specific activator of cytokine, chemokine, and macrophage-colony-stimulating factor receptor genes. J Biol Chem. 1998;273(22):13493-13501.
    • (1998) J Biol Chem , vol.273 , Issue.22 , pp. 13493-13501
    • Williams, S.C.1    Du, Y.2    Schwartz, R.C.3
  • 41
    • 59649125761 scopus 로고    scopus 로고
    • NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway
    • Skokowa J, Lan D, Thakur BK, et al. NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway. Nat Med. 2009;15(2):151-158.
    • (2009) Nat Med , vol.15 , Issue.2 , pp. 151-158
    • Skokowa, J.1    Lan, D.2    Thakur, B.K.3
  • 42
    • 33846622099 scopus 로고    scopus 로고
    • Transcription factors in myeloid development: Balancing differentiation with transformation
    • Rosenbauer F, Tenen DG. Transcription factors in myeloid development: balancing differentiation with transformation. Nat Rev Immunol. 2007;7(2):105-117.
    • (2007) Nat Rev Immunol , vol.7 , Issue.2 , pp. 105-117
    • Rosenbauer, F.1    Tenen, D.G.2
  • 43
    • 0034130509 scopus 로고    scopus 로고
    • Regulation of granulopoiesis by transcription factors and cytokine signals
    • Ward AC, Loeb DM, Soede-Bobok AA, Touw IP, Friedman AD. Regulation of granulopoiesis by transcription factors and cytokine signals. Leukemia. 2000;14(6):973-990.
    • (2000) Leukemia , vol.14 , Issue.6 , pp. 973-990
    • Ward, A.C.1    Loeb, D.M.2    Soede-Bobok, A.A.3    Touw, I.P.4    Friedman, A.D.5
  • 44
    • 0034554849 scopus 로고    scopus 로고
    • Representational difference analysis using myeloid cells from C/EBP epsilon deletional mice
    • Kubota T, Kawano S, Chih DY, et al. Representational difference analysis using myeloid cells from C/EBP epsilon deletional mice. Blood. 2000;96(12):3953-3957.
    • (2000) Blood , vol.96 , Issue.12 , pp. 3953-3957
    • Kubota, T.1    Kawano, S.2    Chih, D.Y.3
  • 45
    • 70449466604 scopus 로고    scopus 로고
    • Neutrophil elastase is severely down-regulated in severe congenital neutropenia independent of ELA2 or HAX1 mutations but dependent on LEF-1
    • Skokowa J, Fobiwe JP, Dan L, Thakur BK, Welte K. Neutrophil elastase is severely down-regulated in severe congenital neutropenia independent of ELA2 or HAX1 mutations but dependent on LEF-1. Blood. 2009;114(14):3044-3051.
    • (2009) Blood , vol.114 , Issue.14 , pp. 3044-3051
    • Skokowa, J.1    Fobiwe, J.P.2    Dan, L.3    Thakur, B.K.4    Welte, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.