-
1
-
-
84877837684
-
Tumor derived mutations of protein tyrosine phosphatase receptor type k affect its function and alter sensitivity to chemotherapeutics in glioma
-
Agarwal S, Al-Keilani MS, Alqudah MA, Sibenaller ZA, Ryken TC, Assem M (2013). Tumor derived mutations of protein tyrosine phosphatase receptor type k affect its function and alter sensitivity to chemotherapeutics in glioma. PLoS One 8, e62852.
-
(2013)
PLoS One
, vol.8
, pp. e62852
-
-
Agarwal, S.1
Al-Keilani, M.S.2
Alqudah, M.A.3
Sibenaller, Z.A.4
Ryken, T.C.5
Assem, M.6
-
2
-
-
0023996419
-
The molecular biology of the Notch locus and the fine tuning of differentiation in Drosophila
-
Artavanis-Tsakonas S (1988). The molecular biology of the Notch locus and the fine tuning of differentiation in Drosophila. Trends Genet 4, 95-100.
-
(1988)
Trends Genet
, vol.4
, pp. 95-100
-
-
Artavanis-Tsakonas, S.1
-
3
-
-
33751078603
-
Canonical notch signaling functions as a commitment switch in the epidermal lineage
-
Blanpain C, Lowry WE, Pasolli HA, Fuchs E (2006). Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev 20, 3022-3035.
-
(2006)
Genes Dev
, vol.20
, pp. 3022-3035
-
-
Blanpain, C.1
Lowry, W.E.2
Pasolli, H.A.3
Fuchs, E.4
-
4
-
-
0345166971
-
Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3
-
Blokzijl A, Dahlqvist C, Reissmann E, Falk A, Moliner A, Lendahl U, Ibanez CF (2003). Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3. J Cell Biol 163, 723-728.
-
(2003)
J Cell Biol
, vol.163
, pp. 723-728
-
-
Blokzijl, A.1
Dahlqvist, C.2
Reissmann, E.3
Falk, A.4
Moliner, A.5
Lendahl, U.6
Ibanez, C.F.7
-
5
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray SJ (2006). Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol 7, 678-689.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
6
-
-
50849104230
-
Notch tumor suppressor function
-
Dotto GP (2008). Notch tumor suppressor function. Oncogene 27, 5115-5123.
-
(2008)
Oncogene
, vol.27
, pp. 5115-5123
-
-
Dotto, G.P.1
-
7
-
-
38049105629
-
Downregulation of the TGF-beta target gene, PTPRK, by the Epstein-Barr virus encoded EBNA1 contributes to the growth and survival of Hodgkin lymphoma cells
-
Flavell JR, Baumforth KR, Wood VH, Davies GL, Wei W, Reynolds GM, Morgan S, Boyce A, Kelly GL, Young LS, Murray PG (2008). Downregulation of the TGF-beta target gene, PTPRK, by the Epstein-Barr virus encoded EBNA1 contributes to the growth and survival of Hodgkin lymphoma cells. Blood 111, 292-301.
-
(2008)
Blood
, vol.111
, pp. 292-301
-
-
Flavell, J.R.1
Baumforth, K.R.2
Wood, V.H.3
Davies, G.L.4
Wei, W.5
Reynolds, G.M.6
Morgan, S.7
Boyce, A.8
Kelly, G.L.9
Young, L.S.10
Murray, P.G.11
-
8
-
-
58149216052
-
Signaling cross-talk between TGF-beta/BMP and other pathways
-
Guo X, Wang XF (2009). Signaling cross-talk between TGF-beta/BMP and other pathways. Cell Res 19, 71-88.
-
(2009)
Cell Res
, vol.19
, pp. 71-88
-
-
Guo, X.1
Wang, X.F.2
-
9
-
-
33748188459
-
Epidermal growth factor receptor biology in head and neck cancer
-
Kalyankrishna S, Grandis JR (2006). Epidermal growth factor receptor biology in head and neck cancer. J Clin Oncol 24, 2666-2672.
-
(2006)
J Clin Oncol
, vol.24
, pp. 2666-2672
-
-
Kalyankrishna, S.1
Grandis, J.R.2
-
10
-
-
48649093670
-
EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer
-
Kolev V, Mandinova A, Guinea-Viniegra J, Hu B, Lefort K, Lambertini C, Neel V, Dummer R, Wagner EF, Dotto GP (2008). EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer. Nat Cell Biol 10, 902-911.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 902-911
-
-
Kolev, V.1
Mandinova, A.2
Guinea-Viniegra, J.3
Hu, B.4
Lefort, K.5
Lambertini, C.6
Neel, V.7
Dummer, R.8
Wagner, E.F.9
Dotto, G.P.10
-
11
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan R, Ilagan MX (2009). The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137, 216-233.
-
(2009)
Cell
, vol.137
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
12
-
-
0034212710
-
Notch signaling is essential for vascular morphogenesis in mice
-
Krebs LT, Xue Y, Norton CR, Shutter JR, Maguire M, Sundberg J P, Gallahan D, Closson V, Kitajewski J, Callahan R, et al. (2000). Notch signaling is essential for vascular morphogenesis in mice. Genes Dev 14, 1343-1352.
-
(2000)
Genes Dev
, vol.14
, pp. 1343-1352
-
-
Krebs, L.T.1
Xue, Y.2
Norton, C.R.3
Shutter, J.R.4
Maguire, M.5
Sundberg, J.P.6
Gallahan, D.7
Closson, V.8
Kitajewski, J.9
Callahan, R.10
-
13
-
-
0345689442
-
Characterization of Notch3-deficient mice: Normal embryonic development and absence of genetic interactions with a Notch1 mutation
-
Krebs LT, Xue Y, Norton CR, Sundberg JP, Beatus P, Lendahl U, Joutel A, Gridley T (2003). Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation. Genesis 37, 139-143.
-
(2003)
Genesis
, vol.37
, pp. 139-143
-
-
Krebs, L.T.1
Xue, Y.2
Norton, C.R.3
Sundberg, J.P.4
Beatus, P.5
Lendahl, U.6
Joutel, A.7
Gridley, T.8
-
14
-
-
3342891403
-
Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression
-
Lefort K, Dotto GP (2004). Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression. Semin Cancer Biol 14, 374-386.
-
(2004)
Semin Cancer Biol
, vol.14
, pp. 374-386
-
-
Lefort, K.1
Dotto, G.P.2
-
15
-
-
33947166199
-
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases
-
Lefort K, Mandinova A, Ostano P, Kolev V, Calpini V, Kolfschoten I, Devgan V, Lieb J, Raffoul W, Hohl D, et al. (2007). Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases. Genes Dev 21, 562-577.
-
(2007)
Genes Dev
, vol.21
, pp. 562-577
-
-
Lefort, K.1
Mandinova, A.2
Ostano, P.3
Kolev, V.4
Calpini, V.5
Kolfschoten, I.6
Devgan, V.7
Lieb, J.8
Raffoul, W.9
Hohl, D.10
-
16
-
-
33644782668
-
Recent insights into the role of Notch signaling in tumorigenesis
-
Leong KG, Karsan A (2006). Recent insights into the role of Notch signaling in tumorigenesis. Blood 107, 2223-2233.
-
(2006)
Blood
, vol.107
, pp. 2223-2233
-
-
Leong, K.G.1
Karsan, A.2
-
17
-
-
0034192461
-
Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters
-
Lowell S, Jones P, Le Roux I, Dunne J, Watt FM (2000). Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. Curr Biol 10, 491-500.
-
(2000)
Curr Biol
, vol.10
, pp. 491-500
-
-
Lowell, S.1
Jones, P.2
Le Roux, I.3
Dunne, J.4
Watt, F.M.5
-
18
-
-
41649088627
-
Multiple roles of Notch signaling in the regulation of epidermal development
-
Moriyama M, Durham AD, Moriyama H, Hasegawa K, Nishikawa S, Radtke F, Osawa M (2008). Multiple roles of Notch signaling in the regulation of epidermal development. Dev Cell 14, 594-604.
-
(2008)
Dev Cell
, vol.14
, pp. 594-604
-
-
Moriyama, M.1
Durham, A.D.2
Moriyama, H.3
Hasegawa, K.4
Nishikawa, S.5
Radtke, F.6
Osawa, M.7
-
19
-
-
0025104027
-
TGF-beta stimulation and inhibition of cell proliferation: New mechanistic insights
-
Moses HL, Yang EY, Pietenpol JA (1990). TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights. Cell 63, 245-247.
-
(1990)
Cell
, vol.63
, pp. 245-247
-
-
Moses, H.L.1
Yang, E.Y.2
Pietenpol, J.A.3
-
20
-
-
0036024023
-
Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma
-
Nickoloff BJ, Qin JZ, Chaturvedi V, Denning MF, Bonish B, Miele L (2002). Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma. Cell Death Differ 9, 842-855.
-
(2002)
Cell Death Differ
, vol.9
, pp. 842-855
-
-
Nickoloff, B.J.1
Qin, J.Z.2
Chaturvedi, V.3
Denning, M.F.4
Bonish, B.5
Miele, L.6
-
21
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
Nicolas M, Wolfer A, Raj K, Kummer JA, Mill P, van Noort M, Hui CC, Clevers H, Dotto G P, Radtke F (2003). Notch1 functions as a tumor suppressor in mouse skin. Nat Genet 33, 416-421.
-
(2003)
Nat Genet
, vol.33
, pp. 416-421
-
-
Nicolas, M.1
Wolfer, A.2
Raj, K.3
Kummer, J.A.4
Mill, P.5
Van Noort, M.6
Hui, C.C.7
Clevers, H.8
Dotto, G.P.9
Radtke, F.10
-
22
-
-
11144356373
-
High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism
-
Okuyama R, Nguyen BC, Talora C, Ogawa E, Tommasi di Vignano A, Lioumi M, Chiorino G, Tagami H, Woo M, Dotto GP (2004). High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism. Dev Cell 6, 551-562.
-
(2004)
Dev Cell
, vol.6
, pp. 551-562
-
-
Okuyama, R.1
Nguyen, B.C.2
Talora, C.3
Ogawa, E.4
Tommasi Di Vignano, A.5
Lioumi, M.6
Chiorino, G.7
Tagami, H.8
Woo, M.9
Dotto, G.P.10
-
23
-
-
38749101987
-
Notch signaling: Its role in epidermal homeostasis and in the pathogenesis of skin diseases
-
Okuyama R, Tagami H, Aiba S (2008). Notch signaling: its role in epidermal homeostasis and in the pathogenesis of skin diseases. J Dermatol Sci 49, 187-194.
-
(2008)
J Dermatol Sci
, vol.49
, pp. 187-194
-
-
Okuyama, R.1
Tagami, H.2
Aiba, S.3
-
24
-
-
7744240345
-
Gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis
-
Pan Y, Lin MH, Tian X, Cheng HT, Gridley T, Shen J, Kopan R (2004). gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev Cell 7, 731-743.
-
(2004)
Dev Cell
, vol.7
, pp. 731-743
-
-
Pan, Y.1
Lin, M.H.2
Tian, X.3
Cheng, H.T.4
Gridley, T.5
Shen, J.6
Kopan, R.7
-
25
-
-
43749094998
-
The epidermal growth factor receptor system in skin repair and inflammation
-
Pastore S, Mascia F, Mariani V, Girolomoni G (2008). The epidermal growth factor receptor system in skin repair and inflammation. J Invest Dermatol 128, 1365-1374.
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1365-1374
-
-
Pastore, S.1
Mascia, F.2
Mariani, V.3
Girolomoni, G.4
-
26
-
-
33747891694
-
Impaired notch signaling promotes de novo squamous cell carcinoma formation
-
Proweller A, Tu L, Lepore JJ, Cheng L, Lu MM, Seykora J, Millar SE, Pear WS, Parmacek MS (2006). Impaired notch signaling promotes de novo squamous cell carcinoma formation. Cancer Res 66, 7438-7444.
-
(2006)
Cancer Res
, vol.66
, pp. 7438-7444
-
-
Proweller, A.1
Tu, L.2
Lepore, J.J.3
Cheng, L.4
Lu, M.M.5
Seykora, J.6
Millar, S.E.7
Pear, W.S.8
Parmacek, M.S.9
-
27
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
-
Radtke F, Raj K (2003). The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer 3, 756-767.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
28
-
-
17844384528
-
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
-
Rangarajan A, Talora C, Okuyama R, Nicolas M, Mammucari C, Oh H, Aster JC, Krishna S, Metzger D, Chambon P, et al. (2001). Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J 20, 3427-3436.
-
(2001)
EMBO J
, vol.20
, pp. 3427-3436
-
-
Rangarajan, A.1
Talora, C.2
Okuyama, R.3
Nicolas, M.4
Mammucari, C.5
Oh, H.6
Aster, J.C.7
Krishna, S.8
Metzger, D.9
Chambon, P.10
-
29
-
-
52649179291
-
Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells
-
Samon JB, Champhekar A, Minter LM, Telfer JC, Miele L, Fauq A, Das P, Golde TE, Osborne BA (2008). Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood 112, 1813-1821.
-
(2008)
Blood
, vol.112
, pp. 1813-1821
-
-
Samon, J.B.1
Champhekar, A.2
Minter, L.M.3
Telfer, J.C.4
Miele, L.5
Fauq, A.6
Das, P.7
Golde, T.E.8
Osborne, B.A.9
-
30
-
-
77955058550
-
Regulation of epidermal keratinocytes by growth factors
-
Shirakata Y (2010). Regulation of epidermal keratinocytes by growth factors. J Dermatol Sci 59, 73-80.
-
(2010)
J Dermatol Sci
, vol.59
, pp. 73-80
-
-
Shirakata, Y.1
-
31
-
-
84898441850
-
DNA methylation of membrane-bound tyrosine phosphatase genes in acute lymphoblastic leukaemia
-
Stevenson WS, Best OG, Przybylla A, Chen Q, Singh N, Koleth M, Pierce S, Kennedy T, Tong W, Kuang SQ, Garcia-Manero G (2013). DNA methylation of membrane-bound tyrosine phosphatase genes in acute lymphoblastic leukaemia. Leukemia 28, 787-793.
-
(2013)
Leukemia
, vol.28
, pp. 787-793
-
-
Stevenson, W.S.1
Best, O.G.2
Przybylla, A.3
Chen, Q.4
Singh, N.5
Koleth, M.6
Pierce, S.7
Kennedy, T.8
Tong, W.9
Kuang, S.Q.10
Garcia-Manero, G.11
-
32
-
-
84879204519
-
Protein tyrosine phosphatase kappa (PTPRK) is a negative regulator of adhesion and invasion of breast cancer cells, and associates with poor prognosis of breast cancer
-
Sun PH, Ye L, Mason MD, Jiang WG (2013). Protein tyrosine phosphatase kappa (PTPRK) is a negative regulator of adhesion and invasion of breast cancer cells, and associates with poor prognosis of breast cancer. J Cancer Res Clin Oncol 139, 1129-1139.
-
(2013)
J Cancer Res Clin Oncol
, vol.139
, pp. 1129-1139
-
-
Sun, P.H.1
Ye, L.2
Mason, M.D.3
Jiang, W.G.4
-
34
-
-
21644440048
-
Activation of Notch1 in the hair follicle leads to cell-fate switch and Mohawk alopecia
-
Uyttendaele H, Panteleyev AA, de Berker D, Tobin DT, Christiano AM (2004). Activation of Notch1 in the hair follicle leads to cell-fate switch and Mohawk alopecia. Differentiation 72, 396-409.
-
(2004)
Differentiation
, vol.72
, pp. 396-409
-
-
Uyttendaele, H.1
Panteleyev, A.A.2
De Berker, D.3
Tobin, D.T.4
Christiano, A.M.5
-
35
-
-
0036683057
-
Role of integrins in regulating epidermal adhesion, growth and differentiation
-
Watt FM (2002). Role of integrins in regulating epidermal adhesion, growth and differentiation. EMBO J 21, 3919-3926.
-
(2002)
EMBO J
, vol.21
, pp. 3919-3926
-
-
Watt, F.M.1
-
36
-
-
41549166020
-
Epidermal Notch signalling: Differentiation, cancer and adhesion
-
Watt FM, Estrach S, Ambler CA (2008). Epidermal Notch signalling: differentiation, cancer and adhesion. Curr Opin Cell Biol 20, 171-179.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 171-179
-
-
Watt, F.M.1
Estrach, S.2
Ambler, C.A.3
-
37
-
-
63649138195
-
Gamma-Secretase in biology and medicine
-
Wolfe MS (2009). gamma-Secretase in biology and medicine. Semin Cell Dev Biol 20, 219-224.
-
(2009)
Semin Cell Dev Biol
, vol.20
, pp. 219-224
-
-
Wolfe, M.S.1
-
38
-
-
75649109715
-
Receptor type protein tyrosine phosphatase-kappa mediates cross-talk between transforming growth factor-beta and epidermal growth factor receptor signaling pathways in human keratinocytes
-
Xu Y, Baker D, Quan T, Baldassare JJ, Voorhees JJ, Fisher GJ (2010). Receptor type protein tyrosine phosphatase-kappa mediates cross-talk between transforming growth factor-beta and epidermal growth factor receptor signaling pathways in human keratinocytes. Mol Biol Cell 21, 29-35.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 29-35
-
-
Xu, Y.1
Baker, D.2
Quan, T.3
Baldassare, J.J.4
Voorhees, J.J.5
Fisher, G.J.6
-
39
-
-
33748743056
-
Oxidative inhibition of receptortype protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes
-
Xu Y, Shao Y, Voorhees JJ, Fisher GJ (2006). Oxidative inhibition of receptortype protein-tyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes. J Biol Chem 281, 27389-27397.
-
(2006)
J Biol Chem
, vol.281
, pp. 27389-27397
-
-
Xu, Y.1
Shao, Y.2
Voorhees, J.J.3
Fisher, G.J.4
-
40
-
-
30044436233
-
Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function
-
Xu Y, Tan LJ, Grachtchouk V, Voorhees JJ, Fisher GJ (2005). Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function. J Biol Chem 280, 42694-42700.
-
(2005)
J Biol Chem
, vol.280
, pp. 42694-42700
-
-
Xu, Y.1
Tan, L.J.2
Grachtchouk, V.3
Voorhees, J.J.4
Fisher, G.J.5
|