Akt-mediated phosphorylation of Oct4 is associated with the proliferation of stem-like cancer cells

Oncology Reports

Volumn 33, Issue 4, 2015, Pages 1621-1629

  Zhao, Qing Wei ^a,b   Zhou, Yan Wen ^a   Li, Wen Xin ^a   Kang, Bo ^a,c   Zhang, Xiao Qian ^a   Yang, Ying ^a   Cheng, Jie ^a,d   Yin, Sheng Yong ^e   Tong, Ying ^b   He, Jian Qin ^a,c   Yao, Hang Ping ^a,c   Zheng, Min ^a,c   Wang, Ying Jie ^a,c  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c Research Center for Diagnosis Treatment of Hepatobiliary Diseases   (China)

^d ZHEJIANG UNIVERSITY   (China)

^e NONE   (China)

Author keywords

Akt; Glioblastoma; Oct4; Phosphorylation; Proliferation; Stem like cancer cells

Indexed keywords

OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN KINASE B; 2-(1'H-INDOLO-3'-CARBONYL)THIAZOLE-4-CARBOXYLIC ACID METHYL ESTER; AKT-I-1,2 COMPOUND; AKT1 PROTEIN, HUMAN; AROMATIC HYDROCARBON RECEPTOR; BENZYLAMINE DERIVATIVE; CULTURE MEDIUM; INDOLE DERIVATIVE; POU5F1 PROTEIN, HUMAN; QUINOXALINE DERIVATIVE; SMALL INTERFERING RNA; THIAZOLE DERIVATIVE; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CELL PROLIFERATION; CELL RENEWAL; CELL SURVIVAL; CONTROLLED STUDY; DNA MICROARRAY; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; MORPHOLOGY; MOUSE; NEURAL STEM CELL; NONHUMAN; OCT4A GENE; ONCOGENE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RNA TRANSLATION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SUMOYLATION; UBIQUITINATION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN TUMOR; CANCER STEM CELL; CELL DIVISION; CELL NUCLEUS; CHEMISTRY; CULTURE MEDIUM; CYTOLOGY; LIVER TUMOR; METABOLISM; MULTICELLULAR SPHEROID; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; RNA INTERFERENCE; TUMOR CELL LINE; XENOGRAFT;

ANIMALS; BENZYLAMINES; BRAIN NEOPLASMS; CARCINOMA, HEPATOCELLULAR; CELL DIVISION; CELL LINE, TUMOR; CELL NUCLEUS; CULTURE MEDIA; GLIOBLASTOMA; HETEROGRAFTS; HUMANS; INDOLES; LIVER NEOPLASMS; MICE; MICE, NUDE; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; QUINOXALINES; RECEPTORS, ARYL HYDROCARBON; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; THIAZOLES;

EID: 84924912271     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.3752     Document Type: Article

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