메뉴 건너뛰기




Volumn 5, Issue 5, 2010, Pages

A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; CELL PROTEIN; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 1C; INHIBITOR OF DIFFERENTIATION 2; MITOGEN ACTIVATED PROTEIN KINASE 4; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN EOMES; PROTEIN HAND1; PROTEIN ISL1; PROTEIN PHC1; PROTEIN PHF17; PROTEIN USP44; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 5; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

EID: 77956269672     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010709     Document Type: Article
Times cited : (84)

References (78)
  • 1
    • 24144497712 scopus 로고    scopus 로고
    • Genetic engineering of human embryonic stem cells with lentiviral vectors
    • Xiong C, Tang DQ, Xie CQ, Zhang L, Xu KF, et al. (2005) Genetic engineering of human embryonic stem cells with lentiviral vectors. Stem Cells Dev 14: 367-377.
    • (2005) Stem Cells Dev , vol.14 , pp. 367-377
    • Xiong, C.1    Tang, D.Q.2    Xie, C.Q.3    Zhang, L.4    Xu, K.F.5
  • 2
    • 34748925353 scopus 로고    scopus 로고
    • The stem cell identity of testicular cancer
    • Clark AT (2007) The stem cell identity of testicular cancer. Stem Cell Rev 3: 49-59.
    • (2007) Stem Cell Rev , vol.3 , pp. 49-59
    • Clark, A.T.1
  • 3
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122: 947-956.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3    Johnstone, S.E.4    Levine, S.S.5
  • 4
    • 28844450086 scopus 로고    scopus 로고
    • Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: Opposite sides of the same coin
    • Andrews PW, Matin MM, Bahrami AR, Damjanov I, Gokhale P, et al. (2005) Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin. Biochem Soc Trans 33: 1526-1530.
    • (2005) Biochem Soc Trans , vol.33 , pp. 1526-1530
    • Andrews, P.W.1    Matin, M.M.2    Bahrami, A.R.3    Damjanov, I.4    Gokhale, P.5
  • 5
    • 0027453115 scopus 로고
    • Retinoic acid-induced differentiation of the developmentally pluripotent human germ cell tumor-derived cell line, NCCIT
    • Damjanov I, Horvat B, Gibas Z (1993) Retinoic acid-induced differentiation of the developmentally pluripotent human germ cell tumor-derived cell line, NCCIT. Lab Invest 68: 220-232.
    • (1993) Lab Invest , vol.68 , pp. 220-232
    • Damjanov, I.1    Horvat, B.2    Gibas, Z.3
  • 6
    • 34249800943 scopus 로고    scopus 로고
    • Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for selfrenewal
    • Greber B, Lehrach H, Adjaye J (2007) Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for selfrenewal. BMC Dev Biol 7: 46.
    • (2007) BMC Dev Biol , vol.7 , pp. 46
    • Greber, B.1    Lehrach, H.2    Adjaye, J.3
  • 7
    • 33846933757 scopus 로고    scopus 로고
    • Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research
    • Josephson R, Ording CJ, Liu Y, Shin S, Lakshmipathy U, et al. (2007) Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research. Stem Cells 25: 437-446.
    • (2007) Stem Cells , vol.25 , pp. 437-446
    • Josephson, R.1    Ording, C.J.2    Liu, Y.3    Shin, S.4    Lakshmipathy, U.5
  • 8
    • 65249106671 scopus 로고    scopus 로고
    • Cdk2ap1 is required for epigenetic silencing of Oct4 during murine embryonic stem cell differentiation
    • Deshpande AM, Dai YS, Kim Y, Kim J, Kimlin L, et al. (2009) Cdk2ap1 is required for epigenetic silencing of Oct4 during murine embryonic stem cell differentiation. J Biol Chem 284: 6043-6047.
    • (2009) J Biol Chem , vol.284 , pp. 6043-6047
    • Deshpande, A.M.1    Dai, Y.S.2    Kim, Y.3    Kim, J.4    Kimlin, L.5
  • 9
    • 33846917472 scopus 로고    scopus 로고
    • Analysis of oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells
    • Babaie Y, Herwig R, Greber B, Brink TC, Wruck W, et al. (2007) Analysis of oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells 25: 500-510.
    • (2007) Stem Cells , vol.25 , pp. 500-510
    • Babaie, Y.1    Herwig, R.2    Greber, B.3    Brink, T.C.4    Wruck, W.5
  • 10
    • 0024462072 scopus 로고
    • Octamer binding proteins confer transcriptional activity in early mouse embryogenesis
    • Scholer HR, Balling R, Hatzopoulos AK, Suzuki N, Gruss P (1989) Octamer binding proteins confer transcriptional activity in early mouse embryogenesis. Embo J 8: 2551-2557.
    • (1989) Embo J , vol.8 , pp. 2551-2557
    • Scholer, H.R.1    Balling, R.2    Hatzopoulos, A.K.3    Suzuki, N.4    Gruss, P.5
  • 11
    • 0032882919 scopus 로고    scopus 로고
    • Developmental expression of specific genes detected in high-quality cDNA libraries from single human preimplantation embryos
    • Adjaye J, Bolton V, Monk M (1999) Developmental expression of specific genes detected in high-quality cDNA libraries from single human preimplantation embryos. Gene 237: 373-383.
    • (1999) Gene , vol.237 , pp. 373-383
    • Adjaye, J.1    Bolton, V.2    Monk, M.3
  • 12
    • 28444495872 scopus 로고    scopus 로고
    • Primary differentiation in the human blastocyst: Comparative molecular portraits of inner cell mass and trophectoderm cells
    • Adjaye J, Huntriss J, Herwig R, BenKahla A, Brink TC, et al. (2005) Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells. Stem Cells 23: 1514-1525.
    • (2005) Stem Cells , vol.23 , pp. 1514-1525
    • Adjaye, J.1    Huntriss, J.2    Herwig, R.3    Benkahla, A.4    Brink, T.C.5
  • 13
    • 0032866451 scopus 로고    scopus 로고
    • Identification of genes expressed in human primordial germ cells at the time of entry of the female germ line into meiosis
    • Goto T, Adjaye J, Rodeck CH, Monk M (1999) Identification of genes expressed in human primordial germ cells at the time of entry of the female germ line into meiosis. Mol Hum Reprod 5: 851-860.
    • (1999) Mol Hum Reprod , vol.5 , pp. 851-860
    • Goto, T.1    Adjaye, J.2    Rodeck, C.H.3    Monk, M.4
  • 14
    • 34250369235 scopus 로고    scopus 로고
    • Identification of an OCT4 and SRY regulatory module using integrated computational and experimental genomics approaches
    • Jin VX, O'Geen H, Iyengar S, Green R, Farnham PJ (2007) Identification of an OCT4 and SRY regulatory module using integrated computational and experimental genomics approaches. Genome Res 17: 807-817.
    • (2007) Genome Res , vol.17 , pp. 807-817
    • Jin, V.X.1    O'Geen, H.2    Iyengar, S.3    Green, R.4    Farnham, P.J.5
  • 15
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, et al. (2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38: 431-440.
    • (2006) Nat Genet , vol.38 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3    Vega, V.B.4    Zhang, W.5
  • 16
    • 55149099432 scopus 로고    scopus 로고
    • Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling
    • Matoba R, Niwa H, Masui S, Ohtsuka S, Carter MG, et al. (2006) Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling. PLoS ONE 1: e26.
    • (2006) PLoS ONE , vol.1
    • Matoba, R.1    Niwa, H.2    Masui, S.3    Ohtsuka, S.4    Carter, M.G.5
  • 17
    • 45249117247 scopus 로고    scopus 로고
    • Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data
    • Sharov AA, Masui S, Sharova LV, Piao Y, Aiba K, et al. (2008) Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data. BMC Genomics 9: 269.
    • (2008) BMC Genomics , vol.9 , pp. 269
    • Sharov, A.A.1    Masui, S.2    Sharova, L.V.3    Piao, Y.4    Aiba, K.5
  • 18
    • 34249914507 scopus 로고    scopus 로고
    • Prediction and testing of novel transcriptional networks regulating embryonic stem cell selfrenewal and commitment
    • Walker E, Ohishi M, Davey RE, Zhang W, Cassar PA, et al. (2007) Prediction and testing of novel transcriptional networks regulating embryonic stem cell selfrenewal and commitment. Cell Stem Cell 1: 71-86.
    • (2007) Cell Stem Cell , vol.1 , pp. 71-86
    • Walker, E.1    Ohishi, M.2    Davey, R.E.3    Zhang, W.4    Cassar, P.A.5
  • 19
    • 67949100470 scopus 로고    scopus 로고
    • In Silico Identification of A Core Regulatory Network of OCT4 In Human Embryonic Stem Cells Using An Integrated Approach
    • Chavez L, Bais AS, Vingron M, Lehrach H, Adjaye J, et al. (2009) In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach.BMC Genomics 10: 314.
    • (2009) BMC Genomics , vol.10 , pp. 314
    • Chavez, L.1    Bais, A.S.2    Vingron, M.3    Lehrach, H.4    Adjaye, J.5
  • 21
    • 33745140886 scopus 로고    scopus 로고
    • Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome
    • Bieda M, Xu X, Singer MA, Green R, Farnham PJ (2006) Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome. Genome Res 16: 595-605.
    • (2006) Genome Res , vol.16 , pp. 595-605
    • Bieda, M.1    Xu, X.2    Singer, M.A.3    Green, R.4    Farnham, P.J.5
  • 22
    • 40449126726 scopus 로고    scopus 로고
    • Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets
    • Johnson DS, Li W, Gordon DB, Bhattacharjee A, Curry B, et al. (2008) Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Res 18: 393-403.
    • (2008) Genome Res , vol.18 , pp. 393-403
    • Johnson, D.S.1    Li, W.2    Gordon, D.B.3    Bhattacharjee, A.4    Curry, B.5
  • 24
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for Annotation, Visualization, and Integrated Discovery
    • Dennis G, Jr., Sherman BT, Hosack DA, Yang J, Gao W, et al. (2003) DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol 4: P3.
    • (2003) Genome Biol , vol.4 , pp. 3
    • Dennis Jr., G.1    Sherman, B.T.2    Hosack, D.A.3    Yang, J.4    Gao, W.5
  • 25
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • da Huang, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 26
    • 34547571030 scopus 로고    scopus 로고
    • G:Profiler-a web-based toolset for functional profiling of gene lists from large-scale experiments
    • Reimand J, Kull M, Peterson H, Hansen J, Vilo J (2007) g:Profiler-a web-based toolset for functional profiling of gene lists from large-scale experiments. Nucleic Acids Res 35: W193-200.
    • (2007) Nucleic Acids Res , vol.35
    • Reimand, J.1    Kull, M.2    Peterson, H.3    Hansen, J.4    Vilo, J.5
  • 27
    • 58149193234 scopus 로고    scopus 로고
    • STRING 8-a global view on proteins and their functional interactions in 630 organisms
    • Jensen LJ, Kuhn M, Stark M, Chaffron S, Creevey C, et al. (2009) STRING 8-a global view on proteins and their functional interactions in 630 organisms. Nucleic Acids Res 37: D412-416.
    • (2009) Nucleic Acids Res , vol.37
    • Jensen, L.J.1    Kuhn, M.2    Stark, M.3    Chaffron, S.4    Creevey, C.5
  • 28
    • 38549096565 scopus 로고    scopus 로고
    • JASPAR, the open access database of transcription factor-binding profiles: New content and tools in the 2008 update
    • Bryne JC, Valen E, Tang MH, Marstrand T, Winther O, et al. (2008) JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update. Nucleic Acids Res 36: D102-106.
    • (2008) Nucleic Acids Res , vol.36
    • Bryne, J.C.1    Valen, E.2    Tang, M.H.3    Marstrand, T.4    Winther, O.5
  • 29
    • 25144442704 scopus 로고    scopus 로고
    • TAMO: A flexible, object-oriented framework for analyzing transcriptional regulation using DNAsequence motifs
    • Gordon DB, Nekludova L, McCallum S, Fraenkel E (2005) TAMO: a flexible, object-oriented framework for analyzing transcriptional regulation using DNAsequence motifs. Bioinformatics 21: 3164-3165.
    • (2005) Bioinformatics , vol.21 , pp. 3164-3165
    • Gordon, D.B.1    Nekludova, L.2    McCallum, S.3    Fraenkel, E.4
  • 30
    • 34547569191 scopus 로고    scopus 로고
    • STAMP: A web tool for exploring DNA-binding motif similarities
    • Mahony S, Benos PV (2007) STAMP: a web tool for exploring DNA-binding motif similarities. Nucleic Acids Res 35: W253-258.
    • (2007) Nucleic Acids Res , vol.35
    • Mahony, S.1    Benos, P.V.2
  • 31
    • 0032536783 scopus 로고    scopus 로고
    • Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice
    • Chan JY, Kwong M, Lu R, Chang J, Wang B, et al. (1998) Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice. Embo J 17: 1779-1787.
    • (1998) Embo J , vol.17 , pp. 1779-1787
    • Chan, J.Y.1    Kwong, M.2    Lu, R.3    Chang, J.4    Wang, B.5
  • 32
    • 0039726828 scopus 로고    scopus 로고
    • The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts
    • Kwong M, Kan YW, Chan JY (1999) The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts. J Biol Chem 274: 37491-37498.
    • (1999) J Biol Chem , vol.274 , pp. 37491-37498
    • Kwong, M.1    Kan, Y.W.2    Chan, J.Y.3
  • 33
    • 70349368602 scopus 로고    scopus 로고
    • The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines
    • Regenbrecht CR, Jung M, Lehrach H, Adjaye J (2008) The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines. BMC Med Genomics 1: 49.
    • (2008) BMC Med Genomics , vol.1 , pp. 49
    • Regenbrecht, C.R.1    Jung, M.2    Lehrach, H.3    Adjaye, J.4
  • 35
    • 50149108009 scopus 로고    scopus 로고
    • Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium
    • Chen YH, Ishii M, Sucov HM, Maxson RE, Jr. (2008) Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium. BMC Dev Biol 8: 75.
    • (2008) BMC Dev Biol , vol.8 , pp. 75
    • Chen, Y.H.1    Ishii, M.2    Sucov, H.M.3    Maxson Jr., R.E.4
  • 37
    • 1442336166 scopus 로고    scopus 로고
    • Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma
    • Clark AT, Rodriguez RT, Bodnar MS, Abeyta MJ, Cedars MI, et al. (2004) Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma. Stem Cells 22: 169-179.
    • (2004) Stem Cells , vol.22 , pp. 169-179
    • Clark, A.T.1    Rodriguez, R.T.2    Bodnar, M.S.3    Abeyta, M.J.4    Cedars, M.I.5
  • 38
    • 36349037021 scopus 로고    scopus 로고
    • Developmental pluripotency-associated 4 (DPPA4) localized in active chromatin inhibits mouse embryonic stem cell differentiation into a primitive ectoderm lineage
    • Masaki H, Nishida T, Kitajima S, Asahina K, Teraoka H (2007) Developmental pluripotency-associated 4 (DPPA4) localized in active chromatin inhibits mouse embryonic stem cell differentiation into a primitive ectoderm lineage. J Biol Chem 282: 33034-33042.
    • (2007) J Biol Chem , vol.282 , pp. 33034-33042
    • Masaki, H.1    Nishida, T.2    Kitajima, S.3    Asahina, K.4    Teraoka, H.5
  • 39
    • 0032128171 scopus 로고    scopus 로고
    • New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2
    • Botquin V, Hess H, Fuhrmann G, Anastassiadis C, Gross MK, et al. (1998) New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2. Genes Dev 12: 2073-2090.
    • (1998) Genes Dev , vol.12 , pp. 2073-2090
    • Botquin, V.1    Hess, H.2    Fuhrmann, G.3    Anastassiadis, C.4    Gross, M.K.5
  • 40
    • 0033639075 scopus 로고    scopus 로고
    • Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimmer configuration
    • Tomilin A, Remenyi A, Lins K, Bak H, Leidel S, et al. (2000) Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimmer configuration. Cell 103: 853-864.
    • (2000) Cell , vol.103 , pp. 853-864
    • Tomilin, A.1    Remenyi, A.2    Lins, K.3    Bak, H.4    Leidel, S.5
  • 41
    • 50849115172 scopus 로고    scopus 로고
    • Analysis of The Mouse Embryonic Stem Cell Regulatory Networks Obtained By ChIP-chip and ChIP-PET
    • Mathur D, Danford TW, Boyer LA, Young RA, Gifford DK, et al. (2008) Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET. Genome Biol 9: R126.
    • (2008) Genome Biol , vol.9
    • Mathur, D.1    Danford, T.W.2    Boyer, L.A.3    Young, R.A.4    Gifford, D.K.5
  • 42
    • 44649117905 scopus 로고    scopus 로고
    • Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
    • Chen X,Xu H,Yuan P,Fang F,Huss M, et al. (2008) Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133: 1106-1117.
    • (2008) Cell , vol.133 , pp. 1106-1117
    • Chen, X.1    Xu, H.2    Yuan, P.3    Fang, F.4    Huss, M.5
  • 43
    • 70450217879 scopus 로고    scopus 로고
    • Human DNA methylomes at base resolution show widespread epigenomic differences
    • Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, et al. (2009) Human DNA methylomes at base resolution show widespread epigenomic differences. Nature.
    • (2009) Nature
    • Lister, R.1    Pelizzola, M.2    Dowen, R.H.3    Hawkins, R.D.4    Hon, G.5
  • 44
    • 33746773659 scopus 로고    scopus 로고
    • Dissecting selfrenewal in stem cells with RNA interference
    • Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, et al. (2006) Dissecting selfrenewal in stem cells with RNA interference. Nature 442: 533-538.
    • (2006) Nature , vol.442 , pp. 533-538
    • Ivanova, N.1    Dobrin, R.2    Lu, R.3    Kotenko, I.4    Levorse, J.5
  • 45
    • 34249876564 scopus 로고    scopus 로고
    • Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
    • Masui S, Nakatake Y, Toyooka Y, Shimosato D, Yagi R, et al. (2007) Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 9: 625-635.
    • (2007) Nat Cell Biol , vol.9 , pp. 625-635
    • Masui, S.1    Nakatake, Y.2    Toyooka, Y.3    Shimosato, D.4    Yagi, R.5
  • 46
    • 57449090247 scopus 로고    scopus 로고
    • Control of early fate decisions in human ES cells by distinct states of TGFss pathway activity
    • Greber B, Lehrach H, Adjaye J (2008) Control of early fate decisions in human ES cells by distinct states of TGFss pathway activity. Stem Cells Dev.
    • (2008) Stem Cells Dev
    • Greber, B.1    Lehrach, H.2    Adjaye, J.3
  • 47
    • 0018079655 scopus 로고
    • Basic principles of ROC analysis
    • Metz CE (1978) Basic principles of ROC analysis. Semin Nucl Med 8: 283-298.
    • (1978) Semin Nucl Med , vol.8 , pp. 283-298
    • Metz, C.E.1
  • 48
    • 14844359620 scopus 로고    scopus 로고
    • Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression
    • Kuroda T, Tada M, Kubota H, Kimura H, Hatano SY, et al. (2005) Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol Cell Biol 25: 2475-2485.
    • (2005) Mol Cell Biol , vol.25 , pp. 2475-2485
    • Kuroda, T.1    Tada, M.2    Kubota, H.3    Kimura, H.4    Hatano, S.Y.5
  • 49
    • 0032797827 scopus 로고    scopus 로고
    • The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2
    • Nishimoto M, Fukushima A, Okuda A, Muramatsu M (1999) The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2. Mol Cell Biol 19: 5453-5465.
    • (1999) Mol Cell Biol , vol.19 , pp. 5453-5465
    • Nishimoto, M.1    Fukushima, A.2    Okuda, A.3    Muramatsu, M.4
  • 50
    • 20344364163 scopus 로고    scopus 로고
    • Oct- 3/4 maintains the proliferative embryonic stem cell state via specific binding to a variant octamer sequence in the regulatory region of the UTF1 locus
    • Nishimoto M, Miyagi S, Yamagishi T, Sakaguchi T, Niwa H, et al. (2005) Oct- 3/4 maintains the proliferative embryonic stem cell state via specific binding to a variant octamer sequence in the regulatory region of the UTF1 locus. Mol Cell Biol 25: 5084-5094.
    • (2005) Mol Cell Biol , vol.25 , pp. 5084-5094
    • Nishimoto, M.1    Miyagi, S.2    Yamagishi, T.3    Sakaguchi, T.4    Niwa, H.5
  • 51
    • 0037383685 scopus 로고    scopus 로고
    • Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell selfrenewal and mouse development
    • Tokuzawa Y, Kaiho E, Maruyama M, Takahashi K, Mitsui K, et al. (2003) Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell selfrenewal and mouse development. Mol Cell Biol 23: 2699-2708.
    • (2003) Mol Cell Biol , vol.23 , pp. 2699-2708
    • Tokuzawa, Y.1    Kaiho, E.2    Maruyama, M.3    Takahashi, K.4    Mitsui, K.5
  • 52
    • 0030820931 scopus 로고    scopus 로고
    • Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on proteinprotein interactions facilitated by a specific spatial arrangement of factor binding sites
    • Ambrosetti DC, Basilico C, Dailey L (1997) Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on proteinprotein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol Cell Biol 17: 6321-6329.
    • (1997) Mol Cell Biol , vol.17 , pp. 6321-6329
    • Ambrosetti, D.C.1    Basilico, C.2    Dailey, L.3
  • 53
    • 58849156573 scopus 로고    scopus 로고
    • A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress
    • Kang J, Gemberling M, Nakamura M, Whitby FG, Handa H, et al. (2009) A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress. Genes Dev 23: 208-222.
    • (2009) Genes Dev , vol.23 , pp. 208-222
    • Kang, J.1    Gemberling, M.2    Nakamura, M.3    Whitby, F.G.4    Handa, H.5
  • 54
    • 0037941585 scopus 로고    scopus 로고
    • Module networks: Identifying regulatory modules and their condition-specific regulators from gene expression data
    • Segal E, Shapira M, Regev A, Pe'er D, Botstein D, et al. (2003) Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data. Nat Genet 34: 166-176.
    • (2003) Nat Genet , vol.34 , pp. 166-176
    • Segal, E.1    Shapira, M.2    Regev, A.3    Pe'er, D.4    Botstein, D.5
  • 55
    • 70350731108 scopus 로고    scopus 로고
    • Distinguishing direct versus indirect transcription factor-dna interactions
    • Gordan R, Hartemink AJ, Bulyk ML (2009) Distinguishing direct versus indirect transcription factor-DNA interactions. Genome Res.
    • (2009) Genome Res
    • Gordan, R.1    Hartemink, A.J.2    Bulyk, M.L.3
  • 56
    • 41149174852 scopus 로고    scopus 로고
    • Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
    • Cole MF, Johnstone SE, Newman JJ, Kagey MH, Young RA (2008) Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells. Genes Dev 22: 746-755.
    • (2008) Genes Dev , vol.22 , pp. 746-755
    • Cole, M.F.1    Johnstone, S.E.2    Newman, J.J.3    Kagey, M.H.4    Young, R.A.5
  • 57
    • 65549095495 scopus 로고    scopus 로고
    • REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells
    • Jorgensen HF, Terry A, Beretta C, Pereira CF, Leleu M, et al. (2009) REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells. Development 136: 715-721.
    • (2009) Development , vol.136 , pp. 715-721
    • Jorgensen, H.F.1    Terry, A.2    Beretta, C.3    Pereira, C.F.4    Leleu, M.5
  • 58
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl HL (1999) Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18: 6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 59
    • 13944273471 scopus 로고    scopus 로고
    • P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
    • Lin T, Chao C, Saito S, Mazur SJ, Murphy ME, et al. (2005) p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 7: 165-171.
    • (2005) Nat Cell Biol , vol.7 , pp. 165-171
    • Lin, T.1    Chao, C.2    Saito, S.3    Mazur, S.J.4    Murphy, M.E.5
  • 60
    • 0026070598 scopus 로고
    • The transcription factor LF-A1 interacts with a bipartite recognition sequence in the promoter regions of several liver-specific genes
    • Ramji DP, Tadros MH, Hardon EM, Cortese R (1991) The transcription factor LF-A1 interacts with a bipartite recognition sequence in the promoter regions of several liver-specific genes. Nucleic Acids Res 19: 1139-1146.
    • (1991) Nucleic Acids Res , vol.19 , pp. 1139-1146
    • Ramji, D.P.1    Tadros, M.H.2    Hardon, E.M.3    Cortese, R.4
  • 61
    • 0347519182 scopus 로고    scopus 로고
    • Ebf gene function is required for coupling neuronal differentiation and cell cycle exit
    • Garcia-Dominguez M, Poquet C, Garel S, Charnay P (2003) Ebf gene function is required for coupling neuronal differentiation and cell cycle exit. Development 130: 6013-6025.
    • (2003) Development , vol.130 , pp. 6013-6025
    • Garcia-Dominguez, M.1    Poquet, C.2    Garel, S.3    Charnay, P.4
  • 62
    • 0038819130 scopus 로고    scopus 로고
    • Pax5 determines B- versus T-cell fate and does not block early myeloid-lineage development
    • Cotta CV, Zhang Z, Kim HG, Klug CA (2003) Pax5 determines B- versus T-cell fate and does not block early myeloid-lineage development. Blood 101: 4342-4346.
    • (2003) Blood , vol.101 , pp. 4342-4346
    • Cotta, C.V.1    Zhang, Z.2    Kim, H.G.3    Klug, C.A.4
  • 63
    • 0028821102 scopus 로고
    • A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor: Retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells
    • Ben-Shushan E, Sharir H, Pikarsky E, Bergman Y (1995) A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor: retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. Mol Cell Biol 15: 1034-1048.
    • (1995) Mol Cell Biol , vol.15 , pp. 1034-1048
    • Ben-Shushan, E.1    Sharir, H.2    Pikarsky, E.3    Bergman, Y.4
  • 64
    • 41649086194 scopus 로고    scopus 로고
    • High-throughput Biochemical Analysis of in-vivo Location Data Reveals Novel Classes of POU5F1(Oct4)/DNA complexes
    • Tantin D, Gemberling M, Callister C, Fairbrother W (2008) High-throughput Biochemical Analysis of in-vivo Location Data Reveals Novel Classes of POU5F1(Oct4)/DNA complexes. Genome Res.
    • (2008) Genome Res
    • Tantin, D.1    Gemberling, M.2    Callister, C.3    Fairbrother, W.4
  • 65
    • 34147113900 scopus 로고    scopus 로고
    • A metaanalysis of human embryonic stem cells transcriptome integrated into a webbased expression atlas
    • Assou S, Le Carrour T, Tondeur S, Strom S, Gabelle A, et al. (2007) A metaanalysis of human embryonic stem cells transcriptome integrated into a webbased expression atlas. Stem Cells 25: 961-973.
    • (2007) Stem Cells , vol.25 , pp. 961-973
    • Assou, S.1    le Carrour, T.2    Tondeur, S.3    Strom, S.4    Gabelle, A.5
  • 66
    • 34247376926 scopus 로고    scopus 로고
    • Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities
    • Stegmeier F, Rape M, Draviam VM, Nalepa G, Sowa ME, et al. (2007) Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities. Nature 446: 876-881.
    • (2007) Nature , vol.446 , pp. 876-881
    • Stegmeier, F.1    Rape, M.2    Draviam, V.M.3    Nalepa, G.4    Sowa, M.E.5
  • 67
    • 0041845266 scopus 로고    scopus 로고
    • CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle
    • Chung HK, Yi YW, Jung NC, Kim D, Suh JM, et al. (2003) CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle. J Biol Chem 278: 28079-28088.
    • (2003) J Biol Chem , vol.278 , pp. 28079-28088
    • Chung, H.K.1    Yi, Y.W.2    Jung, N.C.3    Kim, D.4    Suh, J.M.5
  • 69
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11: 1475-1489.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 70
    • 21644434480 scopus 로고    scopus 로고
    • Transcriptional regulation of nanog by OCT4 and SOX2
    • Rodda DJ, Chew JL, Lim LH, Loh YH, Wang B, et al. (2005) Transcriptional regulation of nanog by OCT4 and SOX2. J Biol Chem 280: 24731-24737.
    • (2005) J Biol Chem , vol.280 , pp. 24731-24737
    • Rodda, D.J.1    Chew, J.L.2    Lim, L.H.3    Loh, Y.H.4    Wang, B.5
  • 71
    • 8744290969 scopus 로고    scopus 로고
    • A novel, highperformance random array platform for quantitative gene expression profiling
    • Kuhn K, Baker SC, Chudin E, Lieu MH, Oeser S, et al. (2004) A novel, highperformance random array platform for quantitative gene expression profiling. Genome Res 14: 2347-2356.
    • (2004) Genome Res , vol.14 , pp. 2347-2356
    • Kuhn, K.1    Baker, S.C.2    Chudin, E.3    Lieu, M.H.4    Oeser, S.5
  • 72
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al. (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80.
    • (2004) Genome Biol , vol.5
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3    Bolstad, B.4    Dettling, M.5
  • 73
    • 18744369640 scopus 로고    scopus 로고
    • Use of within-array replicate spots for assessing differential expression in microarray experiments
    • Smyth GK, Michaud J, Scott HS (2005) Use of within-array replicate spots for assessing differential expression in microarray experiments. Bioinformatics 21: 2067-2075.
    • (2005) Bioinformatics , vol.21 , pp. 2067-2075
    • Smyth, G.K.1    Michaud, J.2    Scott, H.S.3
  • 74
    • 0034628901 scopus 로고    scopus 로고
    • Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae
    • Hughes JD, Estep PW, Tavazoie S, Church GM (2000) Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae. J Mol Biol 296: 1205-1214.
    • (2000) J Mol Biol , vol.296 , pp. 1205-1214
    • Hughes, J.D.1    Estep, P.W.2    Tavazoie, S.3    Church, G.M.4
  • 75
    • 0036324753 scopus 로고    scopus 로고
    • An algorithm for finding protein-DNA binding sites with applications to chromatin-immunoprecipitation microarray experiments
    • Liu XS, Brutlag DL, Liu JS (2002) An algorithm for finding protein-DNA binding sites with applications to chromatin-immunoprecipitation microarray experiments. Nat Biotechnol 20: 835-839.
    • (2002) Nat Biotechnol , vol.20 , pp. 835-839
    • Liu, X.S.1    Brutlag, D.L.2    Liu, J.S.3
  • 76
    • 0028685490 scopus 로고
    • Fitting a mixture model by expectation maximization to discover motifs in biopolymers
    • Bailey TL, Elkan C (1994) Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol 2: 28-36.
    • (1994) Proc Int Conf Intell Syst Mol Biol , vol.2 , pp. 28-36
    • Bailey, T.L.1    Elkan, C.2
  • 78
    • 24044522270 scopus 로고    scopus 로고
    • BioMart and Bioconductor: A powerful link between biological databases and microarray data analysis
    • Durinck S, Moreau Y, Kasprzyk A, Davis S, De Moor B, et al. (2005) BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis. Bioinformatics 21: 3439-3440.
    • (2005) Bioinformatics , vol.21 , pp. 3439-3440
    • Durinck, S.1    Moreau, Y.2    Kasprzyk, A.3    Davis, S.4    de Moor, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.