-
1
-
-
6044269157
-
Self-renewal of teratocarcinoma and embryonic stem cells
-
Chambers I, Smith A (2004) Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene 23: 7150-7160.
-
(2004)
Oncogene
, vol.23
, pp. 7150-7160
-
-
Chambers, I.1
Smith, A.2
-
2
-
-
39149130361
-
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
-
Jaenisch R, Young R (2008) Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132: 567-582.
-
(2008)
Cell
, vol.132
, pp. 567-582
-
-
Jaenisch, R.1
Young, R.2
-
3
-
-
0034837080
-
Molecular mechanism to maintain stem cell renewal of ES cells
-
Niwa H (2001) Molecular mechanism to maintain stem cell renewal of ES cells. Cell Struct Funct 26: 137-148.
-
(2001)
Cell Struct Funct
, vol.26
, pp. 137-148
-
-
Niwa, H.1
-
4
-
-
33745892388
-
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells
-
Suzuki A, Raya A, Kawakami Y, Morita M, Matsui T, et al. (2006) Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells. Proc Natl Acad Sci U S A 103: 10294-10299.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10294-10299
-
-
Suzuki, A.1
Raya, A.2
Kawakami, Y.3
Morita, M.4
Matsui, T.5
-
5
-
-
0344845415
-
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
-
Ying QL, Nichols J, Chambers I, Smith A (2003) BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115: 281-292.
-
(2003)
Cell
, vol.115
, pp. 281-292
-
-
Ying, Q.L.1
Nichols, J.2
Chambers, I.3
Smith, A.4
-
6
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122: 947-956.
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
-
8
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
Chen X, Xu H, Yuan P, Fang F, Huss M, et al. (2008) Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133: 1106-1117.
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
-
9
-
-
0030006923
-
Silencing of the gene for the beta subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-3/ 4
-
Liu L, Roberts RM (1996) Silencing of the gene for the beta subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-3/ 4. J Biol Chem 271: 16683-16689.
-
(1996)
J Biol Chem
, vol.271
, pp. 16683-16689
-
-
Liu, L.1
Roberts, R.M.2
-
10
-
-
0032128171
-
New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2
-
Botquin V, Hess H, Fuhrmann G, Anastassiadis C, Gross MK, et al. (1998) New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2. Genes Dev 12: 2073-2090.
-
(1998)
Genes Dev
, vol.12
, pp. 2073-2090
-
-
Botquin, V.1
Hess, H.2
Fuhrmann, G.3
Anastassiadis, C.4
Gross, M.K.5
-
11
-
-
0025291459
-
Oct-4: A germline-specific transcription factor mapping to the mouse t-complex
-
Scholer HR, Dressler GR, Balling R, Rohdewohld H, Gruss P (1990) Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. Embo J 9: 2185-2195.
-
(1990)
Embo J
, vol.9
, pp. 2185-2195
-
-
Scholer, H.R.1
Dressler, G.R.2
Balling, R.3
Rohdewohld, H.4
Gruss, P.5
-
12
-
-
0032008045
-
Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation
-
Pesce M, Wang X, Wolgemuth DJ, Scholer H (1998) Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation. Mech Dev 71: 89-98.
-
(1998)
Mech Dev
, vol.71
, pp. 89-98
-
-
Pesce, M.1
Wang, X.2
Wolgemuth, D.J.3
Scholer, H.4
-
13
-
-
0032582513
-
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
-
Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, et al. (1998) Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95: 379-391.
-
(1998)
Cell
, vol.95
, pp. 379-391
-
-
Nichols, J.1
Zevnik, B.2
Anastassiadis, K.3
Niwa, H.4
Klewe-Nebenius, D.5
-
14
-
-
0034028901
-
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
-
Niwa H, Miyazaki J, Smith AG (2000) Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 24: 372-376.
-
(2000)
Nat Genet
, vol.24
, pp. 372-376
-
-
Niwa, H.1
Miyazaki, J.2
Smith, A.G.3
-
15
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, et al. (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113: 631-642.
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
-
16
-
-
33746773659
-
Dissecting self-renewal in stem cells with RNA interference
-
Ivanova N, Dobrin R, Lu R, Kotenko I, Levorse J, et al. (2006) Dissecting self-renewal in stem cells with RNA interference. Nature 442: 533-538.
-
(2006)
Nature
, vol.442
, pp. 533-538
-
-
Ivanova, N.1
Dobrin, R.2
Lu, R.3
Kotenko, I.4
Levorse, J.5
-
17
-
-
0042161878
-
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers
-
Remenyi A, Lins K, Nissen LJ, Reinbold R, Scholer HR, et al. (2003) Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes Dev 17: 2048-2059.
-
(2003)
Genes Dev
, vol.17
, pp. 2048-2059
-
-
Remenyi, A.1
Lins, K.2
Nissen, L.J.3
Reinbold, R.4
Scholer, H.R.5
-
18
-
-
0034791092
-
Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping
-
Remenyi A, Tomilin A, Pohl E, Lins K, Philippsen A, et al. (2001) Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping. Mol Cell 8: 569-580.
-
(2001)
Mol Cell
, vol.8
, pp. 569-580
-
-
Remenyi, A.1
Tomilin, A.2
Pohl, E.3
Lins, K.4
Philippsen, A.5
-
19
-
-
0028821102
-
A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor: Retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells
-
Ben-Shushan E, Sharir H, Pikarsky E, Bergman Y (1995) A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor: retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells. Mol Cell Biol 15: 1034-1048.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1034-1048
-
-
Ben-Shushan, E.1
Sharir, H.2
Pikarsky, E.3
Bergman, Y.4
-
20
-
-
0019947366
-
Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line
-
McBurney MW, Jones-Villeneuve EM, Edwards MK, Anderson PJ (1982) Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line. Nature 299: 165-167.
-
(1982)
Nature
, vol.299
, pp. 165-167
-
-
McBurney, M.W.1
Jones-Villeneuve, E.M.2
Edwards, M.K.3
Anderson, P.J.4
-
21
-
-
0037047155
-
Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes
-
Paquin J, Danalache BA, Jankowski M, McCann SM, Gutkowska J (2002) Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes. Proc Natl Acad Sci U S A 99: 9550-9555.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 9550-9555
-
-
Paquin, J.1
Danalache, B.A.2
Jankowski, M.3
McCann, S.M.4
Gutkowska, J.5
-
22
-
-
0028156027
-
Primitive streak mesoderm-like cell lines expressing Pax-3 and Hox gene autoinducing activities
-
Pruitt SC (1994) Primitive streak mesoderm-like cell lines expressing Pax-3 and Hox gene autoinducing activities. Development 120: 37-47.
-
(1994)
Development
, vol.120
, pp. 37-47
-
-
Pruitt, S.C.1
-
23
-
-
0027959928
-
Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation
-
Palmieri SL, Peter W, Hess H, Scholer HR (1994) Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. Dev Biol 166: 259-267.
-
(1994)
Dev Biol
, vol.166
, pp. 259-267
-
-
Palmieri, S.L.1
Peter, W.2
Hess, H.3
Scholer, H.R.4
-
24
-
-
2542469858
-
Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination
-
Xu HM, Liao B, Zhang QJ, Wang BB, Li H, et al. (2004) Wwp2, an E3 ubiquitin ligase that targets transcription factor Oct-4 for ubiquitination. J Biol Chem 279: 23495-23503.
-
(2004)
J Biol Chem
, vol.279
, pp. 23495-23503
-
-
Xu, H.M.1
Liao, B.2
Zhang, Q.J.3
Wang, B.B.4
Li, H.5
-
25
-
-
0042622251
-
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs
-
Obenauer JC, Cantley LC, Yaffe MB (2003) Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res 31: 3635-3641.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3635-3641
-
-
Obenauer, J.C.1
Cantley, L.C.2
Yaffe, M.B.3
-
26
-
-
0033639075
-
Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration
-
Tomilin A, Remenyi A, Lins K, Bak H, Leidel S, et al. (2000) Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration. Cell 103: 853-864.
-
(2000)
Cell
, vol.103
, pp. 853-864
-
-
Tomilin, A.1
Remenyi, A.2
Lins, K.3
Bak, H.4
Leidel, S.5
-
27
-
-
4344707501
-
Identification of a nuclear localization signal in OCT4 and generation of a dominant negative mutant by its ablation
-
Pan G, Qin B, Liu N, Scholer HR, Pei D (2004) Identification of a nuclear localization signal in OCT4 and generation of a dominant negative mutant by its ablation. J Biol Chem 279: 37013-37020.
-
(2004)
J Biol Chem
, vol.279
, pp. 37013-37020
-
-
Pan, G.1
Qin, B.2
Liu, N.3
Scholer, H.R.4
Pei, D.5
-
28
-
-
33645381936
-
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
-
Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, et al. (2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38: 431-440.
-
(2006)
Nat Genet
, vol.38
, pp. 431-440
-
-
Loh, Y.H.1
Wu, Q.2
Chew, J.L.3
Vega, V.B.4
Zhang, W.5
-
29
-
-
0032480888
-
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
-
de Rooij J, Zwartkruis FJ, Verheijen MH, Cool RH, Nijman SM, et al. (1998) Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature 396: 474-477.
-
(1998)
Nature
, vol.396
, pp. 474-477
-
-
de Rooij, J.1
Zwartkruis, F.J.2
Verheijen, M.H.3
Cool, R.H.4
Nijman, S.M.5
-
30
-
-
20744441357
-
Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes
-
Robidoux J, Cao W, Quan H, Daniel KW, Moukdar F, et al. (2005) Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes. Mol Cell Biol 25: 5466-5479.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 5466-5479
-
-
Robidoux, J.1
Cao, W.2
Quan, H.3
Daniel, K.W.4
Moukdar, F.5
-
31
-
-
0041315574
-
cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension
-
Christensen AE, Selheim F, de Rooij J, Dremier S, Schwede F, et al. (2003) cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension. J Biol Chem 278: 35394-35402.
-
(2003)
J Biol Chem
, vol.278
, pp. 35394-35402
-
-
Christensen, A.E.1
Selheim, F.2
de Rooij, J.3
Dremier, S.4
Schwede, F.5
-
32
-
-
55149099432
-
-
PLoS
-
Matoba R, Niwa H, Masui S, Ohtsuka S, Carter MG, et al. (2006) Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling. PLoS ONE 1: e26.
-
(2006)
Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling
, vol.ONE 1
-
-
Matoba, R.1
Niwa, H.2
Masui, S.3
Ohtsuka, S.4
Carter, M.G.5
-
33
-
-
33751092246
-
A protein interaction network for pluripotency of embryonic stem cells
-
Wang J, Rao S, Chu J, Shen X, Levasseur DN, et al. (2006) A protein interaction network for pluripotency of embryonic stem cells. Nature 444: 364-368.
-
(2006)
Nature
, vol.444
, pp. 364-368
-
-
Wang, J.1
Rao, S.2
Chu, J.3
Shen, X.4
Levasseur, D.N.5
-
34
-
-
0025060177
-
A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells
-
Okamoto K, Okazawa H, Okuda A, Sakai M, Muramatsu M, et al. (1990) A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 60: 461-472.
-
(1990)
Cell
, vol.60
, pp. 461-472
-
-
Okamoto, K.1
Okazawa, H.2
Okuda, A.3
Sakai, M.4
Muramatsu, M.5
-
35
-
-
0034806106
-
A role of N-cadherin in neuronal differentiation of embryonic carcinoma P19 cells
-
Gao X, Bian W, Yang J, Tang K, Kitani H, et al. (2001) A role of N-cadherin in neuronal differentiation of embryonic carcinoma P19 cells. Biochem Biophys Res Commun 284: 1098-1103.
-
(2001)
Biochem Biophys Res Commun
, vol.284
, pp. 1098-1103
-
-
Gao, X.1
Bian, W.2
Yang, J.3
Tang, K.4
Kitani, H.5
-
36
-
-
33645132331
-
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis
-
Feldman N, Gerson A, Fang J, Li E, Zhang Y, et al. (2006) G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat Cell Biol 8: 188-194.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 188-194
-
-
Feldman, N.1
Gerson, A.2
Fang, J.3
Li, E.4
Zhang, Y.5
-
37
-
-
33845441511
-
Differential recruitment of methylated CpG binding domains by the orphan receptor GCNF initiates the repression and silencing of Oct4 expression
-
Gu P, Le Menuet D, Chung AC, Cooney AJ (2006) Differential recruitment of methylated CpG binding domains by the orphan receptor GCNF initiates the repression and silencing of Oct4 expression. Mol Cell Biol 26: 9471-9483.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9471-9483
-
-
Gu, P.1
Le Menuet, D.2
Chung, A.C.3
Cooney, A.J.4
-
38
-
-
0025742707
-
Differential phosphorylation of the transcription factor Oct1 during the cell cycle
-
Roberts SB, Segil N, Heintz N (1991) Differential phosphorylation of the transcription factor Oct1 during the cell cycle. Science 253: 1022-1026.
-
(1991)
Science
, vol.253
, pp. 1022-1026
-
-
Roberts, S.B.1
Segil, N.2
Heintz, N.3
-
39
-
-
0037520693
-
Stem cell pluripotency and transcription factor Oct4
-
Pan GJ, Chang ZY, Scholer HR, Pei D (2002) Stem cell pluripotency and transcription factor Oct4. Cell Res 12: 321-329.
-
(2002)
Cell Res
, vol.12
, pp. 321-329
-
-
Pan, G.J.1
Chang, Z.Y.2
Scholer, H.R.3
Pei, D.4
-
40
-
-
1642293248
-
p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene
-
Cao W, Daniel KW, Robidoux J, Puigserver P, Medvedev AV, et al. (2004) p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. Mol Cell Biol 24: 3057-3067.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 3057-3067
-
-
Cao, W.1
Daniel, K.W.2
Robidoux, J.3
Puigserver, P.4
Medvedev, A.V.5
-
41
-
-
0037499970
-
MatchMiner: A tool for batch navigation among gene and gene product identifiers
-
Bussey KJ, Kane D, Sunshine M, Narasimhan S, Nishizuka S, et al. (2003) MatchMiner: a tool for batch navigation among gene and gene product identifiers. Genome Biol 4: R27.
-
(2003)
Genome Biol
, vol.4
-
-
Bussey, K.J.1
Kane, D.2
Sunshine, M.3
Narasimhan, S.4
Nishizuka, S.5
-
42
-
-
23144464901
-
WebGestalt: An integrated system for exploring gene sets in various biological contexts
-
Zhang B, Kirov S, Snoddy J (2005) WebGestalt: an integrated system for exploring gene sets in various biological contexts. Nucleic Acids Res 33: W741-748.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Zhang, B.1
Kirov, S.2
Snoddy, J.3
-
43
-
-
4444221565
-
UCSF Chimera-a visualization system for exploratory research and analysis
-
Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, et al. (2004) UCSF Chimera-a visualization system for exploratory research and analysis. J Comput Chem 25: 1605-1612.
-
(2004)
J Comput Chem
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
|