The Aspergillus nidulans proline permease as a model for understanding the factors determining substrate binding and specificity of fungal amino acid transporters

Journal of Biological Chemistry

Volumn 290, Issue 10, 2015, Pages 6141-6155

  Gournas, Christos ^a   Evangelidis, Thomas ^b   Athanasopoulos, Alexandros ^a   Mikros, Emmanuel ^b   Sophianopoulou, Vicky ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

SUBSTRATES; YEAST;

AMINO ACID SUBSTITUTION; AMINO ACID TRANSPORTER; AMINO ACID UPTAKE; ASPERGILLUS NIDULANS; CONFORMATIONAL CHANGE; SEQUENCE SIMILARITY; SPECIFICITY PROFILE; SUBSTRATE BINDING;

AMINO ACIDS;

ALANINE; AMINO ACID TRANSPORTER; ARGININE; AZETIDINE 2 CARBOXYLIC ACID; GLYCINE; PROLINE; PROTEIN PRNB; UNCLASSIFIED DRUG; FUNGAL PROTEIN; PROLINE TRANSPORTER;

AMINO ACID SUBSTITUTION; ARTICLE; ASPERGILLUS NIDULANS; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; FUNGUS GROWTH; GENE FREQUENCY; HYDROGEN BOND; MOLECULAR DOCKING; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; METABOLISM; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

EMERICELLA NIDULANS; FUNGI; SACCHAROMYCES CEREVISIAE;

AMINO ACID SUBSTITUTION; AMINO ACID TRANSPORT SYSTEMS; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ASPERGILLUS NIDULANS; CRYSTALLOGRAPHY, X-RAY; FUNGAL PROTEINS; PROLINE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84924873142     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.612069     Document Type: Article

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