-
1
-
-
2642709177
-
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
-
Palella Jr FJ, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, Satten GA, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med. 1998;338:853-60.
-
(1998)
N Engl J Med.
, vol.338
, pp. 853-860
-
-
Palella, F.J.1
Delaney, K.M.2
Moorman, A.C.3
Loveless, M.O.4
Fuhrer, J.5
Satten, G.A.6
-
2
-
-
0038579210
-
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
-
Siliciano JD, Kajdas J, Finzi D, Quinn TC, Chadwick K, Margolick JB, et al. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells. Nat Med. 2003;9:727-8.
-
(2003)
Nat Med.
, vol.9
, pp. 727-728
-
-
Siliciano, J.D.1
Kajdas, J.2
Finzi, D.3
Quinn, T.C.4
Chadwick, K.5
Margolick, J.B.6
-
3
-
-
19244380883
-
CCR3 and CCR5 are coreceptors for HIV-1 infection of microglia
-
He J, Chen Y, Farzan M, Choe H, Ohagen A, Gartner S, et al. CCR3 and CCR5 are coreceptors for HIV-1 infection of microglia. Nature. 1997;385:645-9.
-
(1997)
Nature.
, vol.385
, pp. 645-649
-
-
He, J.1
Chen, Y.2
Farzan, M.3
Choe, H.4
Ohagen, A.5
Gartner, S.6
-
4
-
-
0031466811
-
Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: Implications for HIV primary infection
-
Zaitseva M, Blauvelt A, Lee S, Lapham CK, Klaus-Kovtun V, Mostowski H, et al. Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: implications for HIV primary infection. Nat Med. 1997;3:1369-75.
-
(1997)
Nat Med.
, vol.3
, pp. 1369-1375
-
-
Zaitseva, M.1
Blauvelt, A.2
Lee, S.3
Lapham, C.K.4
Klaus-Kovtun, V.5
Mostowski, H.6
-
5
-
-
0032522668
-
Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry
-
Rubbert A, Combadiere C, Ostrowski M, Arthos J, Dybul M, Machado E, et al. Dendritic cells express multiple chemokine receptors used as coreceptors for HIV entry. J Immunol. 1998;160:3933-41.
-
(1998)
J Immunol.
, vol.160
, pp. 3933-3941
-
-
Rubbert, A.1
Combadiere, C.2
Ostrowski, M.3
Arthos, J.4
Dybul, M.5
McHado, E.6
-
6
-
-
0032532353
-
Peripheral bloodderived CD34+ progenitor cells: CXC chemokine receptor 4 and CC chemokine receptor 5 expression and infection by HIV
-
Ruiz ME, Cicala C, Arthos J, Kinter A, Catanzaro AT, Adelsberger J, et al. Peripheral bloodderived CD34+ progenitor cells: CXC chemokine receptor 4 and CC chemokine receptor 5 expression and infection by HIV. J Immunol. 1998;161:4169-76.
-
(1998)
J Immunol.
, vol.161
, pp. 4169-4176
-
-
Ruiz, M.E.1
Cicala, C.2
Arthos, J.3
Kinter, A.4
Catanzaro, A.T.5
Adelsberger, J.6
-
7
-
-
0034312298
-
The plasma membrane as a combat zone in the HIV battlefield
-
Doms RW, Trono D. The plasma membrane as a combat zone in the HIV battlefield. Genes Dev. 2000;14:2677-88.
-
(2000)
Genes Dev.
, vol.14
, pp. 2677-2688
-
-
Doms, R.W.1
Trono, D.2
-
8
-
-
0033988632
-
Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: Soluble CD4 activates Env for coreceptor- dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120
-
Salzwedel K, Smith ED, Dey B, Berger EA. Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor- dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120. J Virol. 2000;74:326-33.
-
(2000)
J Virol.
, vol.74
, pp. 326-333
-
-
Salzwedel, K.1
Smith, E.D.2
Dey, B.3
Berger, E.A.4
-
9
-
-
63449129628
-
Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: Roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia
-
Agrawal L, Maxwell CR, Peters PJ, Clapham PR, Liu SM, Mackay CR, et al. Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia. J Gen Virol. 2009;90:710-22.
-
(2009)
J Gen Virol.
, vol.90
, pp. 710-722
-
-
Agrawal, L.1
Maxwell, C.R.2
Peters, P.J.3
Clapham, P.R.4
Liu, S.M.5
McKay, C.R.6
-
10
-
-
56649109712
-
Live cell imaging of the HIV-1 life cycle
-
Campbell EM, Hope TJ. Live cell imaging of the HIV-1 life cycle. Trends Microbiol. 2008;16:580-7.
-
(2008)
Trends Microbiol.
, vol.16
, pp. 580-587
-
-
Campbell, E.M.1
Hope, T.J.2
-
11
-
-
0041663465
-
Intracellular trafficking of HIV-1 cores: Journey to the center of the cell
-
Dvorin JD, Malim MH. Intracellular trafficking of HIV-1 cores: journey to the center of the cell. Curr Top Microbiol Immunol. 2003;281:179-208.
-
(2003)
Curr Top Microbiol Immunol.
, vol.281
, pp. 179-208
-
-
Dvorin, J.D.1
Malim, M.H.2
-
12
-
-
0036150082
-
Mechanistic aspects of HIV-1 reverse transcription initiation
-
Harrich D, Hooker B. Mechanistic aspects of HIV-1 reverse transcription initiation. Rev Med Virol. 2002;12:31-45.
-
(2002)
Rev Med Virol.
, vol.12
, pp. 31-45
-
-
Harrich, D.1
Hooker, B.2
-
13
-
-
0027376309
-
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
-
Bukrinsky MI, Haggerty S, Dempsey MP, Sharova N, Adzhubel A, Spitz L, et al. A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells. Nature. 1993;365:666-9.
-
(1993)
Nature.
, vol.365
, pp. 666-669
-
-
Bukrinsky, M.I.1
Haggerty, S.2
Dempsey, M.P.3
Sharova, N.4
Adzhubel, A.5
Spitz, L.6
-
14
-
-
0028239060
-
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells
-
Heinzinger NK, Bukinsky MI, Haggerty SA, Ragland AM, Kewalramani V, Lee MA, et al. The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells. Proc Natl Acad Sci U S A. 1994;91:7311-5.
-
(1994)
Proc Natl Acad Sci U S A.
, vol.91
, pp. 7311-7315
-
-
Heinzinger, N.K.1
Bukinsky, M.I.2
Haggerty, S.A.3
Ragland, A.M.4
Kewalramani, V.5
Lee, M.A.6
-
15
-
-
0030987672
-
HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway
-
Gallay P, Hope T, Chin D, Trono D. HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway. Proc Natl Acad Sci U S A. 1997; 94:9825-30.
-
(1997)
Proc Natl Acad Sci U S A.
, vol.94
, pp. 9825-9830
-
-
Gallay, P.1
Hope, T.2
Chin, D.3
Trono, D.4
-
16
-
-
0037162715
-
HIV-1 integration in the human genome favors active genes and local hotspots
-
Schroder AR, Shinn P, Chen H, Berry C, Ecker JR, Bushman F. HIV-1 integration in the human genome favors active genes and local hotspots. Cell. 2002;110:521-9.
-
(2002)
Cell.
, vol.110
, pp. 521-529
-
-
Schroder, A.R.1
Shinn, P.2
Chen, H.3
Berry, C.4
Ecker, J.R.5
Bushman, F.6
-
17
-
-
0023513563
-
Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product
-
Kao SY, Calman AF, Luciw PA, Peterlin BM. Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product. Nature. 1987;330:489-93.
-
(1987)
Nature.
, vol.330
, pp. 489-493
-
-
Kao, S.Y.1
Calman, A.F.2
Luciw, P.A.3
Peterlin, B.M.4
-
18
-
-
0028290825
-
Control of RNA initiation and elongation at the HIV-1 promoter
-
Jones KA, Peterlin BM. Control of RNA initiation and elongation at the HIV-1 promoter. Annu Rev Biochem. 1994;63:717-43.
-
(1994)
Annu Rev Biochem.
, vol.63
, pp. 717-743
-
-
Jones, K.A.1
Peterlin, B.M.2
-
19
-
-
0033604520
-
Tat transactivation: A model for the regulation of eukaryotic transcriptional elongation
-
Taube R, Fujinaga K, Wimmer J, Barboric M, Peterlin BM. Tat transactivation: a model for the regulation of eukaryotic transcriptional elongation. Virology. 1999;264:245-53.
-
(1999)
Virology.
, vol.264
, pp. 245-253
-
-
Taube, R.1
Fujinaga, K.2
Wimmer, J.3
Barboric, M.4
Peterlin, B.M.5
-
22
-
-
0027615759
-
The acute retroviral syndrome and the pathogenesis of HIV-1 infection
-
Clark SJ, Shaw GM. The acute retroviral syndrome and the pathogenesis of HIV-1 infection. Semin Immunol. 1993;5:149-55.
-
(1993)
Semin Immunol.
, vol.5
, pp. 149-155
-
-
Clark, S.J.1
Shaw, G.M.2
-
23
-
-
77249123298
-
Mechanisms of HIV latency: An emerging picture of complexity
-
Margolis DM. Mechanisms of HIV latency: an emerging picture of complexity. Curr HIV/ AIDS Rep. 2010;7:37-43.
-
(2010)
Curr HIV/ AIDS Rep.
, vol.7
, pp. 37-43
-
-
Margolis, D.M.1
-
25
-
-
0028792184
-
In vivo fate of HIV- 1- infected T cells: Quantitative analysis of the transition to stable latency
-
Chun TW, Finzi D, Margolick J, Chadwick K, Schwartz D, Siliciano RF. In vivo fate of HIV- 1- infected T cells: quantitative analysis of the transition to stable latency. Nat Med. 1995;1:1284-90.
-
(1995)
Nat Med.
, vol.1
, pp. 1284-1290
-
-
Chun, T.W.1
Finzi, D.2
Margolick, J.3
Chadwick, K.4
Schwartz, D.5
Siliciano, R.F.6
-
26
-
-
0032555117
-
Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection
-
Chun TW, Engel D, Berrey MM, Shea T, Corey L, Fauci AS. Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection. Proc Natl Acad Sci U S A. 1998;95:8869-73.
-
(1998)
Proc Natl Acad Sci U S A.
, vol.95
, pp. 8869-8873
-
-
Chun, T.W.1
Engel, D.2
Berrey, M.M.3
Shea, T.4
Corey, L.5
Fauci, A.S.6
-
27
-
-
22744441386
-
Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity
-
Weinberger LS, Burnett JC, Toettcher JE, Arkin AP, Schaffer DV. Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity. Cell. 2005;122:169-82.
-
(2005)
Cell.
, vol.122
, pp. 169-182
-
-
Weinberger, L.S.1
Burnett, J.C.2
Toettcher, J.E.3
Arkin, A.P.4
Schaffer, D.V.5
-
28
-
-
59249086373
-
Control of stochastic gene expression by host factors at the HIV promoter
-
Burnett JC, Miller-Jensen K, Shah PS, Arkin AP, Schaffer DV. Control of stochastic gene expression by host factors at the HIV promoter. PLoS Pathog. 2009;5:e1000260.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Burnett, J.C.1
Miller-Jensen, K.2
Shah, P.S.3
Arkin, A.P.4
Schaffer, D.V.5
-
29
-
-
84886769508
-
Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure
-
Ho Y-C, Shan L, Hosmane Nina N, Wang J, Laskey Sarah B, Rosenbloom Daniel IS, et al. Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure. Cell. 2013;155:540-51.
-
(2013)
Cell.
, vol.155
, pp. 540-551
-
-
Ho, Y.-C.1
Shan, L.2
Hosmane Nina, N.3
Wang, J.4
Laskey Sarah, B.5
Rosenbloom Daniel, I.S.6
-
31
-
-
14744284227
-
HIV-1 nef suppression by virally encoded microRNA
-
Omoto S, Ito M, Tsutsumi Y, Ichikawa Y, Okuyama H, Brisibe EA, et al. HIV-1 nef suppression by virally encoded microRNA. Retrovirology. 2004;1:44.
-
(2004)
Retrovirology.
, vol.1
, pp. 44
-
-
Omoto, S.1
Ito, M.2
Tsutsumi, Y.3
Ichikawa, Y.4
Okuyama, H.5
Brisibe, E.A.6
-
32
-
-
19344370167
-
Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing
-
Bennasser Y, Le SY, Benkirane M, Jeang KT. Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing. Immunity. 2005;22:607-19.
-
(2005)
Immunity.
, vol.22
, pp. 607-619
-
-
Bennasser, Y.1
Le, S.Y.2
Benkirane, M.3
Jeang, K.T.4
-
33
-
-
14744297918
-
Regulation of human immunodeficiency virus 1 transcription by nef microRNA
-
Omoto S, Fujii YR. Regulation of human immunodeficiency virus 1 transcription by nef microRNA. J Gen Virol. 2005;86:751-5.
-
(2005)
J Gen Virol.
, vol.86
, pp. 751-755
-
-
Omoto, S.1
Fujii, Y.R.2
-
34
-
-
33646365600
-
Are viral-encoded microRNAs mediating latent HIV-1 infection?
-
Weinberg MS, Morris KV. Are viral-encoded microRNAs mediating latent HIV-1 infection? DNA Cell Biol. 2006;25:223-31.
-
(2006)
DNA Cell Biol.
, vol.25
, pp. 223-231
-
-
Weinberg, M.S.1
Morris, K.V.2
-
35
-
-
33646745522
-
The interplay between virus infection and the cellular RNA interference machinery
-
Berkhout B, Haasnoot J. The interplay between virus infection and the cellular RNA interference machinery. FEBS Lett. 2006;580:2896-902.
-
(2006)
FEBS Lett.
, vol.580
, pp. 2896-2902
-
-
Berkhout, B.1
Haasnoot, J.2
-
36
-
-
34948817683
-
Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes
-
Huang J, Wang F, Argyris E, Chen K, Liang Z, Tian H, et al. Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes. Nat Med. 2007;13:1241-7.
-
(2007)
Nat Med.
, vol.13
, pp. 1241-1247
-
-
Huang, J.1
Wang, F.2
Argyris, E.3
Chen, K.4
Liang, Z.5
Tian, H.6
-
37
-
-
34249774568
-
Transcriptional silencing of the TMS1/ ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells
-
Zhang C, Li H, Zhou G, Zhang Q, Zhang T, Li J, et al. Transcriptional silencing of the TMS1/ ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells. J Pathol. 2007;212:134-42.
-
(2007)
J Pathol.
, vol.212
, pp. 134-142
-
-
Zhang, C.1
Li, H.2
Zhou, G.3
Zhang, Q.4
Zhang, T.5
Li, J.6
-
38
-
-
0029919356
-
Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation
-
Van Lint C, Emiliani S, Ott M, Verdin E. Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. EMBO J. 1996;15:1112-20.
-
(1996)
EMBO J.
, vol.15
, pp. 1112-1120
-
-
Van Lint, C.1
Emiliani, S.2
Ott, M.3
Verdin, E.4
-
39
-
-
0346993663
-
Recruitment of SWI/SNF to the human immunodeficiency virus type 1 promoter
-
Henderson A, Holloway A, Reeves R, Tremethick DJ. Recruitment of SWI/SNF to the human immunodeficiency virus type 1 promoter. Mol Cell Biol. 2004;24:389-97.
-
(2004)
Mol Cell Biol.
, vol.24
, pp. 389-397
-
-
Henderson, A.1
Holloway, A.2
Reeves, R.3
Tremethick, D.J.4
-
40
-
-
0033929108
-
The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1
-
Coull JJ, Romerio F, Sun JM, Volker JL, Galvin KM, Davie JR, et al. The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone deacetylase 1. J Virol. 2000;74:6790-9.
-
(2000)
J Virol.
, vol.74
, pp. 6790-6799
-
-
Coull, J.J.1
Romerio, F.2
Sun, J.M.3
Volker, J.L.4
Galvin, K.M.5
Davie, J.R.6
-
41
-
-
30444431914
-
NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
-
Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J. 2006;25:139-49.
-
(2006)
EMBO J.
, vol.25
, pp. 139-149
-
-
Williams, S.A.1
Chen, L.F.2
Kwon, H.3
Ruiz-Jarabo, C.M.4
Verdin, E.5
Greene, W.C.6
-
42
-
-
35148858784
-
c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter
-
Jiang G, Espeseth A, Hazuda DJ, Margolis DM. c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter. J Virol. 2007;81:10914-23.
-
(2007)
J Virol.
, vol.81
, pp. 10914-10923
-
-
Jiang, G.1
Espeseth, A.2
Hazuda, D.J.3
Margolis, D.M.4
-
43
-
-
33846536395
-
Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing
-
Marban C, Suzanne S, Dequiedt F, de Walque S, Redel L, Van Lint C, et al. Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing. EMBO J. 2007;26:412-23.
-
(2007)
EMBO J.
, vol.26
, pp. 412-423
-
-
Marban, C.1
Suzanne, S.2
Dequiedt, F.3
de Walque, S.4
Redel, L.5
Van Lint, C.6
-
44
-
-
57349090221
-
Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency
-
Pearson R, Kim YK, Hokello J, Lassen K, Friedman J, Tyagi M, et al. Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency. J Virol. 2008;82:12291-303.
-
(2008)
J Virol.
, vol.82
, pp. 12291-12303
-
-
Pearson, R.1
Kim, Y.K.2
Hokello, J.3
Lassen, K.4
Friedman, J.5
Tyagi, M.6
-
45
-
-
77953313393
-
Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction
-
Tyagi M, Pearson RJ, Karn J. Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction. J Virol. 2010;84:6425-37.
-
(2010)
J Virol.
, vol.84
, pp. 6425-6437
-
-
Tyagi, M.1
Pearson, R.J.2
Karn, J.3
-
46
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Consortium EP, Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, et al. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489:57-74.
-
(2012)
Nature.
, vol.489
, pp. 57-74
-
-
Consortium, E.P.1
Bernstein, B.E.2
Birney, E.3
Dunham, I.4
Green, E.D.5
Gunter, C.6
-
47
-
-
79960911703
-
The reality of pervasive transcription
-
discussion e1102
-
Clark MB, Amaral PP, Schlesinger FJ, Dinger ME, Taft RJ, Rinn JL, et al. The reality of pervasive transcription. PLoS Biol. 2011;9:e1000625. discussion e1102.
-
(2011)
PLoS Biol.
, vol.9
-
-
Clark, M.B.1
Amaral, P.P.2
Schlesinger, F.J.3
Dinger, M.E.4
Taft, R.J.5
Rinn, J.L.6
-
48
-
-
84891923027
-
Perspectives on the mechanism of transcriptional regulation by long non-coding RNAs
-
Roberts TC, Morris KV, Weinberg MS. Perspectives on the mechanism of transcriptional regulation by long non-coding RNAs. Epigenetics. 2013;9:13-20.
-
(2013)
Epigenetics.
, vol.9
, pp. 13-20
-
-
Roberts, T.C.1
Morris, K.V.2
Weinberg, M.S.3
-
49
-
-
41849131453
-
RNA and transcriptional modulation of gene expression
-
Hawkins PG, Morris KV. RNA and transcriptional modulation of gene expression. Cell Cycle. 2008;7:602-7.
-
(2008)
Cell Cycle.
, vol.7
, pp. 602-607
-
-
Hawkins, P.G.1
Morris, K.V.2
-
50
-
-
10344250458
-
Components of the DNA methylation system of chromatin control are RNA-binding proteins
-
Jeffery L, Nakielny S. Components of the DNA methylation system of chromatin control are RNA-binding proteins. J Biol Chem. 2004;279:49479-87.
-
(2004)
J Biol Chem.
, vol.279
, pp. 49479-49487
-
-
Jeffery, L.1
Nakielny, S.2
-
51
-
-
31044433795
-
The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells
-
Weinberg MS, Villeneuve LM, Ehsani A, Amarzguioui M, Aagaard L, Chen ZX, et al. The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells. RNA. 2006;12:256-62.
-
(2006)
RNA.
, vol.12
, pp. 256-262
-
-
Weinberg, M.S.1
Villeneuve, L.M.2
Ehsani, A.3
Amarzguioui, M.4
Aagaard, L.5
Chen, Z.X.6
-
52
-
-
34547626629
-
Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells
-
Han J, Kim D, Morris KV. Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells. Proc Natl Acad Sci U S A. 2007;104:12422-7.
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, pp. 12422-12427
-
-
Han, J.1
Kim, D.2
Morris, K.V.3
-
53
-
-
49749133953
-
Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs
-
Gonzalez S, Pisano DG, Serrano M. Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs. Cell Cycle. 2008;7:2601-8.
-
(2008)
Cell Cycle.
, vol.7
, pp. 2601-2608
-
-
Gonzalez, S.1
Pisano, D.G.2
Serrano, M.3
-
54
-
-
53149132028
-
Closed chromatin architecture is induced by an RNA duplex targeting the HIV-1 promoter region
-
Suzuki K, Juelich T, Lim H, Ishida T, Watanebe T, Cooper DA, et al. Closed chromatin architecture is induced by an RNA duplex targeting the HIV-1 promoter region. J Biol Chem. 2008;283:23353-63.
-
(2008)
J Biol Chem.
, vol.283
, pp. 23353-23363
-
-
Suzuki, K.1
Juelich, T.2
Lim, H.3
Ishida, T.4
Watanebe, T.5
Cooper, D.A.6
-
55
-
-
38049155825
-
Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA
-
Yu W, Gius D, Onyango P, Muldoon-Jacobs K, Karp J, Feinberg AP, et al. Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA. Nature. 2008;451:202-6.
-
(2008)
Nature.
, vol.451
, pp. 202-206
-
-
Yu, W.1
Gius, D.2
Onyango, P.3
Muldoon-Jacobs, K.4
Karp, J.5
Feinberg, A.P.6
-
56
-
-
66249108936
-
Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells
-
Hawkins PG, Santoso S, Adams C, Anest V, Morris KV. Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells. Nucleic Acids Res. 2009;37: 2984-95.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 2984-2995
-
-
Hawkins, P.G.1
Santoso, S.2
Adams, C.3
Anest, V.4
Morris, K.V.5
-
57
-
-
33751324105
-
Human Immunodeficiency Virus-Type 1 LTR DNA contains an intrinsic gene producing antisense RNA and protein products
-
Ludwig LB, Ambrus Jr JL, Krawczyk KA, Sharma S, Brooks S, Hsiao CB, et al. Human Immunodeficiency Virus-Type 1 LTR DNA contains an intrinsic gene producing antisense RNA and protein products. Retrovirology. 2006;3:80.
-
(2006)
Retrovirology.
, vol.3
, pp. 80
-
-
Ludwig, L.B.1
Ambrus, J.L.2
Krawczyk, K.A.3
Sharma, S.4
Brooks, S.5
Hsiao, C.B.6
-
58
-
-
36849011656
-
Detection, characterization and regulation of antisense transcripts in HIV-1
-
Landry S, Halin M, Lefort S, Audet B, Vaquero C, Mesnard JM, et al. Detection, characterization and regulation of antisense transcripts in HIV-1. Retrovirology. 2007;4:71.
-
(2007)
Retrovirology.
, vol.4
, pp. 71
-
-
Landry, S.1
Halin, M.2
Lefort, S.3
Audet, B.4
Vaquero, C.5
Mesnard, J.M.6
-
59
-
-
84860615730
-
HIV- 1- encoded antisense RNA suppresses viral replication for a prolonged period
-
Kobayashi-Ishihara M, Yamagishi M, Hara T, Matsuda Y, Takahashi R, Miyake A, et al. HIV- 1- encoded antisense RNA suppresses viral replication for a prolonged period. Retrovirology. 2012;9:38.
-
(2012)
Retrovirology.
, vol.9
, pp. 38
-
-
Kobayashi-Ishihara, M.1
Yamagishi, M.2
Hara, T.3
Matsuda, Y.4
Takahashi, R.5
Miyake, A.6
-
60
-
-
33751001588
-
Silencing of HIV-1 with RNA interference: A multiple shRNA approach
-
ter Brake O, Konstantinova P, Ceylan M, Berkhout B. Silencing of HIV-1 with RNA interference: a multiple shRNA approach. Mol Ther. 2006;14:883-92.
-
(2006)
Mol Ther.
, vol.14
, pp. 883-892
-
-
ter Brake, O.1
Konstantinova, P.2
Ceylan, M.3
Berkhout, B.4
-
61
-
-
56349155978
-
Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs
-
Aagaard LA, Zhang J, von Eije KJ, Li H, Saetrom P, Amarzguioui M, et al. Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Ther. 2008;15:1536-49.
-
(2008)
Gene Ther.
, vol.15
, pp. 1536-1549
-
-
Aagaard, L.A.1
Zhang, J.2
von Eije, K.J.3
Li, H.4
Saetrom, P.5
Amarzguioui, M.6
-
62
-
-
44349164025
-
Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron
-
Liu YP, Haasnoot J, ter Brake O, Berkhout B, Konstantinova P. Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron. Nucleic Acids Res. 2008;36: 2811-24.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 2811-2824
-
-
Liu, Y.P.1
Haasnoot, J.2
ter Brake, O.3
Berkhout, B.4
Konstantinova, P.5
-
63
-
-
49749095063
-
The efficacy of generating three independent anti-HIV-1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA
-
Saayman S, Barichievy S, Capovilla A, Morris KV, Arbuthnot P, Weinberg MS. The efficacy of generating three independent anti-HIV-1 siRNAs from a single U6 RNA Pol III-expressed long hairpin RNA. PLoS One. 2008;3:e2602.
-
(2008)
PLoS One.
, vol.3
-
-
Saayman, S.1
Barichievy, S.2
Capovilla, A.3
Morris, K.V.4
Arbuthnot, P.5
Weinberg, M.S.6
-
64
-
-
44849109205
-
Multiple shRNA expressing vector enhances efficiency of gene silencing
-
Song J, Giang A, Lu Y, Pang S, Chiu R. Multiple shRNA expressing vector enhances efficiency of gene silencing. BMB Rep. 2008;41:358-62.
-
(2008)
BMB Rep.
, vol.41
, pp. 358-362
-
-
Song, J.1
Giang, A.2
Lu, Y.3
Pang, S.4
Chiu, R.5
-
65
-
-
77957807722
-
Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors
-
Saayman S, Arbuthnot P, Weinberg MS. Deriving four functional anti-HIV siRNAs from a single Pol III-generated transcript comprising two adjacent long hairpin RNA precursors. Nucleic Acids Res. 2010;38:6652-63.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 6652-6663
-
-
Saayman, S.1
Arbuthnot, P.2
Weinberg, M.S.3
-
66
-
-
84858980105
-
Tailored enrichment strategy detects low abundant small noncoding RNAs in HIV-1 infected cells
-
Althaus CF, Vongrad V, Niederost B, Joos B, Di Giallonardo F, Rieder P, et al. Tailored enrichment strategy detects low abundant small noncoding RNAs in HIV-1 infected cells. Retrovirology. 2012;9:27.
-
(2012)
Retrovirology.
, vol.9
, pp. 27
-
-
Althaus, C.F.1
Vongrad, V.2
Niederost, B.3
Joos, B.4
Di Giallonardo, F.5
Rieder, P.6
-
67
-
-
84855295489
-
Deep sequencing of virus-infected cells reveals HIV-encoded small RNAs
-
Schopman NC, Willemsen M, Liu YP, Bradley T, van Kampen A, Baas F, et al. Deep sequencing of virus-infected cells reveals HIV-encoded small RNAs. Nucleic Acids Res. 2012; 40:414-27.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 414-427
-
-
Schopman, N.C.1
Willemsen, M.2
Liu, Y.P.3
Bradley, T.4
van Kampen, A.5
Baas, F.6
-
68
-
-
34548304523
-
HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR
-
Klase Z, Kale P, Winograd R, Gupta MV, Heydarian M, Berro R, et al. HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR. BMC Mol Biol. 2007;8:63.
-
(2007)
BMC Mol Biol.
, vol.8
, pp. 63
-
-
Klase, Z.1
Kale, P.2
Winograd, R.3
Gupta, M.V.4
Heydarian, M.5
Berro, R.6
-
69
-
-
42449121863
-
Identification of functional microRNAs released through asymmetrical processing of HIV-1 TAR element
-
Ouellet DL, Plante I, Landry P, Barat C, Janelle ME, Flamand L, et al. Identification of functional microRNAs released through asymmetrical processing of HIV-1 TAR element. Nucleic Acids Res. 2008;36:2353-65.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 2353-2365
-
-
Ouellet, D.L.1
Plante, I.2
Landry, P.3
Barat, C.4
Janelle, M.E.5
Flamand, L.6
-
70
-
-
62749139614
-
HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression
-
Klase Z, Winograd R, Davis J, Carpio L, Hildreth R, Heydarian M, et al. HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression. Retrovirology. 2009;6:18.
-
(2009)
Retrovirology.
, vol.6
, pp. 18
-
-
Klase, Z.1
Winograd, R.2
Davis, J.3
Carpio, L.4
Hildreth, R.5
Heydarian, M.6
-
71
-
-
84881285298
-
Regulation of host gene expression by HIV-1 TAR microRNAs
-
Ouellet DL, Vigneault-Edwards J, Letourneau K, Gobeil LA, Plante I, Burnett JC, et al. Regulation of host gene expression by HIV-1 TAR microRNAs. Retrovirology. 2013;10:86.
-
(2013)
Retrovirology.
, vol.10
, pp. 86
-
-
Ouellet, D.L.1
Vigneault-Edwards, J.2
Letourneau, K.3
Gobeil, L.A.4
Plante, I.5
Burnett, J.C.6
-
72
-
-
57149110631
-
Bidirectional transcription directs both transcriptional gene activation and suppression in human cells
-
Morris KV, Santoso S, Turner AM, Pastori C, Hawkins PG. Bidirectional transcription directs both transcriptional gene activation and suppression in human cells. PLoS Genet. 2008;4: e1000258.
-
(2008)
PLoS Genet.
, vol.4
-
-
Morris, K.V.1
Santoso, S.2
Turner, A.M.3
Pastori, C.4
Hawkins, P.G.5
-
73
-
-
79952255050
-
Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5
-
Hawkins PG, Morris KV. Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5. Transcription. 2010;1:165-75.
-
(2010)
Transcription.
, vol.1
, pp. 165-175
-
-
Hawkins, P.G.1
Morris, K.V.2
-
74
-
-
84876177255
-
A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells
-
Johnsson P, Ackley A, Vidarsdottir L, Lui WO, Corcoran M, Grander D, et al. A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells. Nat Struct Mol Biol. 2013;20:440-6.
-
(2013)
Nat Struct Mol Biol.
, vol.20
, pp. 440-446
-
-
Johnsson, P.1
Ackley, A.2
Vidarsdottir, L.3
Lui, W.O.4
Corcoran, M.5
Grander, D.6
-
75
-
-
84902183146
-
An HIVencoded antisense long noncoding RNA epigenetically regulates viral transcription
-
Saayman S, Ackley A, Turner AM, Famiglietti M, Bosque A, Clemson M, et al. An HIVencoded antisense long noncoding RNA epigenetically regulates viral transcription. Mol Ther. 2014;22:1164-75.
-
(2014)
Mol Ther.
, vol.22
, pp. 1164-1175
-
-
Saayman, S.1
Ackley, A.2
Turner, A.M.3
Famiglietti, M.4
Bosque, A.5
Clemson, M.6
-
76
-
-
33947385291
-
Suppression of microRNA-silencing pathway by HIV-1 during virus replication
-
Triboulet R, Mari B, Lin YL, Chable-Bessia C, Bennasser Y, Lebrigand K, et al. Suppression of microRNA-silencing pathway by HIV-1 during virus replication. Science. 2007;315: 1579-82.
-
(2007)
Science.
, vol.315
, pp. 1579-1582
-
-
Triboulet, R.1
Mari, B.2
Lin, Y.L.3
Chable-Bessia, C.4
Bennasser, Y.5
Lebrigand, K.6
-
77
-
-
67449126871
-
Cellular microRNA and P bodies modulate host-HIV-1 interactions
-
Nathans R, Chu CY, Serquina AK, Lu CC, Cao H, Rana TM. Cellular microRNA and P bodies modulate host-HIV-1 interactions. Mol Cell. 2009;34:696-709.
-
(2009)
Mol Cell.
, vol.34
, pp. 696-709
-
-
Nathans, R.1
Chu, C.Y.2
Serquina, A.K.3
Lu, C.C.4
Cao, H.5
Rana, T.M.6
-
78
-
-
61449173947
-
Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication
-
Ahluwalia JK, Khan SZ, Soni K, Rawat P, Gupta A, Hariharan M, et al. Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication. Retrovirology. 2008;5:117.
-
(2008)
Retrovirology.
, vol.5
, pp. 117
-
-
Ahluwalia, J.K.1
Khan, S.Z.2
Soni, K.3
Rawat, P.4
Gupta, A.5
Hariharan, M.6
-
79
-
-
84863346515
-
Interplay between HIV-1 infection and host microRNAs
-
Sun G, Li H, Wu X, Covarrubias M, Scherer L, Meinking K, et al. Interplay between HIV-1 infection and host microRNAs. Nucleic Acids Res. 2012;40:2181-96.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 2181-2196
-
-
Sun, G.1
Li, H.2
Wu, X.3
Covarrubias, M.4
Scherer, L.5
Meinking, K.6
-
80
-
-
84870342928
-
The extent of sequence complementarity correlates with the potency of cellular miRNA-mediated restriction of HIV-1
-
Houzet L, Klase Z, Yeung ML, Wu A, Le SY, Quinones M, et al. The extent of sequence complementarity correlates with the potency of cellular miRNA-mediated restriction of HIV-1. Nucleic Acids Res. 2012;40:11684-96.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 11684-11696
-
-
Houzet, L.1
Klase, Z.2
Yeung, M.L.3
Wu, A.4
Le, S.Y.5
Quinones, M.6
-
81
-
-
59249084325
-
miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1
-
Sung TL, Rice AP. miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1. PLoS Pathog. 2009;5:e1000263.
-
(2009)
PLoS Pathog.
, vol.5
-
-
Sung, T.L.1
Rice, A.P.2
-
82
-
-
84875248780
-
miR-132 enhances HIV-1 replication
-
Chiang K, Liu H, Rice AP. miR-132 enhances HIV-1 replication. Virology. 2013;438:1-4.
-
(2013)
Virology.
, vol.438
, pp. 1-4
-
-
Chiang, K.1
Liu, H.2
Rice, A.P.3
-
83
-
-
84874614275
-
NEAT1 long noncoding RNA and paraspeckle bodies modulate HIV-1 posttranscriptional expression
-
Zhang Q, Chen CY, Yedavalli VS, Jeang KT. NEAT1 long noncoding RNA and paraspeckle bodies modulate HIV-1 posttranscriptional expression. MBio. 2013;4:e00596-12.
-
(2013)
MBio.
, vol.4
, pp. e00596-e00612
-
-
Zhang, Q.1
Chen, C.Y.2
Yedavalli, V.S.3
Jeang, K.T.4
-
84
-
-
84879166632
-
Therapeutic targeting of non-coding RNAs
-
Roberts TC, Wood MJ. Therapeutic targeting of non-coding RNAs. Essays Biochem. 2013;54:127-45.
-
(2013)
Essays Biochem.
, vol.54
, pp. 127-145
-
-
Roberts, T.C.1
Wood, M.J.2
-
85
-
-
24644483623
-
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
-
Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P. Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science. 2005;309:1577-81.
-
(2005)
Science.
, vol.309
, pp. 1577-1581
-
-
Jopling, C.L.1
Yi, M.2
Lancaster, A.M.3
Lemon, S.M.4
Sarnow, P.5
-
86
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
-
Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, Munk ME, et al. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science. 2010;327:198-201.
-
(2010)
Science.
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
Hildebrandt-Eriksen, E.S.2
Petri, A.3
Persson, R.4
Lindow, M.5
Munk, M.E.6
-
87
-
-
4344705410
-
Small interfering RNA-induced transcriptional gene silencing in human cells
-
Morris KV, Chan SW, Jacobsen SE, Looney DJ. Small interfering RNA-induced transcriptional gene silencing in human cells. Science. 2004;305:1289-92.
-
(2004)
Science.
, vol.305
, pp. 1289-1292
-
-
Morris, K.V.1
Chan, S.W.2
Jacobsen, S.E.3
Looney, D.J.4
-
88
-
-
34249930701
-
Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells
-
Kim JW, Zhang YH, Zern MA, Rossi JJ, Wu J. Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells. Biochem Biophys Res Commun. 2007;359:292-7.
-
(2007)
Biochem Biophys Res Commun.
, vol.359
, pp. 292-297
-
-
Kim, J.W.1
Zhang, Y.H.2
Zern, M.A.3
Rossi, J.J.4
Wu, J.5
-
89
-
-
34547095270
-
Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis
-
Pulukuri SM, Rao JS. Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis. Cancer Res. 2007;67: 6637-46.
-
(2007)
Cancer Res.
, vol.67
, pp. 6637-6646
-
-
Pulukuri, S.M.1
Rao, J.S.2
-
90
-
-
63649088662
-
Mobilization-competent lentiviral vector-mediated sustained transcriptional modulation of HIV-1 expression
-
Turner AM, De La Cruz J, Morris KV. Mobilization-competent lentiviral vector-mediated sustained transcriptional modulation of HIV-1 expression. Mol Ther. 2009;17:360-8.
-
(2009)
Mol Ther.
, vol.17
, pp. 360-368
-
-
Turner, A.M.1
De La Cruz, J.2
Morris, K.V.3
-
91
-
-
33748368912
-
Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells
-
Kim DH, Villeneuve LM, Morris KV, Rossi JJ. Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat Struct Mol Biol. 2006;13:793-7.
-
(2006)
Nat Struct Mol Biol.
, vol.13
, pp. 793-797
-
-
Kim, D.H.1
Villeneuve, L.M.2
Morris, K.V.3
Rossi, J.J.4
-
93
-
-
65549158866
-
Transcriptional inhibition of Hoxd4 expression by miRNA-10a in human breast cancer cells
-
Tan Y, Zhang B, Wu T, Skogerbo G, Zhu X, Guo X, et al. Transcriptional inhibition of Hoxd4 expression by miRNA-10a in human breast cancer cells. BMC Mol Biol. 2009;10:12.
-
(2009)
BMC Mol Biol.
, vol.10
, pp. 12
-
-
Tan, Y.1
Zhang, B.2
Wu, T.3
Skogerbo, G.4
Zhu, X.5
Guo, X.6
-
94
-
-
84857784512
-
Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells
-
Benhamed M, Herbig U, Ye T, Dejean A, Bischof O. Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells. Nat Cell Biol. 2012;14: 266-75.
-
(2012)
Nat Cell Biol.
, vol.14
, pp. 266-275
-
-
Benhamed, M.1
Herbig, U.2
Ye, T.3
Dejean, A.4
Bischof, O.5
-
95
-
-
84860319206
-
Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression
-
Zardo G, Ciolfi A, Vian L, Starnes LM, Billi M, Racanicchi S, et al. Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression. Blood. 2012;119:4034-46.
-
(2012)
Blood.
, vol.119
, pp. 4034-4046
-
-
Zardo, G.1
Ciolfi, A.2
Vian, L.3
Starnes, L.M.4
Billi, M.5
Racanicchi, S.6
-
96
-
-
84888580397
-
A comprehensive characterization of the nuclear microRNA repertoire of post-mitotic neurons
-
Khudayberdiev SA, Zampa F, Rajman M, Schratt G. A comprehensive characterization of the nuclear microRNA repertoire of post-mitotic neurons. Front Mol Neurosci. 2013;6:43.
-
(2013)
Front Mol Neurosci.
, vol.6
, pp. 43
-
-
Khudayberdiev, S.A.1
Zampa, F.2
Rajman, M.3
Schratt, G.4
-
97
-
-
56649122127
-
Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells
-
Ohrt T, Mutze J, Staroske W, Weinmann L, Hock J, Crell K, et al. Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells. Nucleic Acids Res. 2008;36:6439-49.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 6439-6449
-
-
Ohrt, T.1
Mutze, J.2
Staroske, W.3
Weinmann, L.4
Hock, J.5
Crell, K.6
-
98
-
-
84892544892
-
RNAi factors are present and active in human cell nuclei
-
Gagnon KT, Li L, Chu Y, Janowski BA, Corey DR. RNAi factors are present and active in human cell nuclei. Cell Rep. 2014;6:211-21.
-
(2014)
Cell Rep.
, vol.6
, pp. 211-221
-
-
Gagnon, K.T.1
Li, L.2
Chu, Y.3
Janowski, B.A.4
Corey, D.R.5
-
99
-
-
64549113392
-
Retroviral delivery of promoter-targeted shRNA induces long-term silencing of HIV-1 transcription
-
Yamagishi M, Ishida T, Miyake A, Cooper DA, Kelleher AD, Suzuki K, et al. Retroviral delivery of promoter-targeted shRNA induces long-term silencing of HIV-1 transcription. Microbes Infect. 2009;11:500-8.
-
(2009)
Microbes Infect.
, vol.11
, pp. 500-508
-
-
Yamagishi, M.1
Ishida, T.2
Miyake, A.3
Cooper, D.A.4
Kelleher, A.D.5
Suzuki, K.6
-
100
-
-
84856010588
-
Transcriptional gene silencing of HPV16 E6/E7 induces growth inhibition via apoptosis in vitro and in vivo
-
Zhou J, Peng C, Li B, Wang F, Zhou C, Hong D, et al. Transcriptional gene silencing of HPV16 E6/E7 induces growth inhibition via apoptosis in vitro and in vivo. Gynecol Oncol. 2012;124:296-302.
-
(2012)
Gynecol Oncol.
, vol.124
, pp. 296-302
-
-
Zhou, J.1
Peng, C.2
Li, B.3
Wang, F.4
Zhou, C.5
Hong, D.6
-
101
-
-
31044436469
-
Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region
-
Suzuki K, Shijuuku T, Fukamachi T, Zaunders J, Guillemin G, Cooper D, et al. Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region. J RNAi Gene Silencing. 2005;1:66-78.
-
(2005)
J RNAi Gene Silencing.
, vol.1
, pp. 66-78
-
-
Suzuki, K.1
Shijuuku, T.2
Fukamachi, T.3
Zaunders, J.4
Guillemin, G.5
Cooper, D.6
-
102
-
-
39849098733
-
Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro
-
Lim HG, Suzuki K, Cooper DA, Kelleher AD. Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro. Mol Ther. 2008;16:565-70.
-
(2008)
Mol Ther.
, vol.16
, pp. 565-570
-
-
Lim, H.G.1
Suzuki, K.2
Cooper, D.A.3
Kelleher, A.D.4
-
103
-
-
81255176941
-
Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific
-
Suzuki K, Ishida T, Yamagishi M, Ahlenstiel C, Swaminathan S, Marks K, et al. Transcriptional gene silencing of HIV-1 through promoter targeted RNA is highly specific. RNA Biol. 2011;8:1035-46.
-
(2011)
RNA Biol.
, vol.8
, pp. 1035-1046
-
-
Suzuki, K.1
Ishida, T.2
Yamagishi, M.3
Ahlenstiel, C.4
Swaminathan, S.5
Marks, K.6
-
104
-
-
85015372182
-
Promoter targeting shRNA suppresses HIV-1 infection in vivo through transcriptional gene silencing
-
Suzuki K, Hattori S, Marks K, Ahlenstiel C, Maeda Y, Ishida T, et al. Promoter targeting shRNA suppresses HIV-1 infection in vivo through transcriptional gene silencing. Mol Ther Nucleic Acids. 2013;2:e137.
-
(2013)
Mol Ther Nucleic Acids.
, vol.2
-
-
Suzuki, K.1
Hattori, S.2
Marks, K.3
Ahlenstiel, C.4
Maeda, Y.5
Ishida, T.6
-
105
-
-
84861670544
-
Characterization of an HIV-targeted transcriptional gene-silencing RNA in primary cells
-
Turner AM, Ackley AM, Matrone MA, Morris KV. Characterization of an HIV-targeted transcriptional gene-silencing RNA in primary cells. Hum Gene Ther. 2012;23:473-83.
-
(2012)
Hum Gene Ther.
, vol.23
, pp. 473-483
-
-
Turner, A.M.1
Ackley, A.M.2
Matrone, M.A.3
Morris, K.V.4
-
106
-
-
0001633495
-
Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study
-
Dean M, Carrington M, Winkler C, Huttley GA, Smith MW, Allikmets R, et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science. 1996;273:1856-62.
-
(1996)
Science.
, vol.273
, pp. 1856-1862
-
-
Dean, M.1
Carrington, M.2
Winkler, C.3
Huttley, G.A.4
Smith, M.W.5
Allikmets, R.6
-
107
-
-
84878459431
-
Reactivation of latent HIV by histone deacetylase inhibitors
-
Shirakawa K, Chavez L, Hakre S, Calvanese V, Verdin E. Reactivation of latent HIV by histone deacetylase inhibitors. Trends Microbiol. 2013;21:277-85.
-
(2013)
Trends Microbiol.
, vol.21
, pp. 277-285
-
-
Shirakawa, K.1
Chavez, L.2
Hakre, S.3
Calvanese, V.4
Verdin, E.5
-
108
-
-
84864203255
-
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
-
Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, Crooks AM, et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature. 2012;487:482-5.
-
(2012)
Nature.
, vol.487
, pp. 482-485
-
-
Archin, N.M.1
Liberty, A.L.2
Kashuba, A.D.3
Choudhary, S.K.4
Kuruc, J.D.5
Crooks, A.M.6
-
109
-
-
84886768526
-
Stochastic fate selection in HIV-infected patients
-
Weinberger AD, Weinberger LS. Stochastic fate selection in HIV-infected patients. Cell. 2013;155:497-9.
-
(2013)
Cell.
, vol.155
, pp. 497-499
-
-
Weinberger, A.D.1
Weinberger, L.S.2
-
110
-
-
33847081733
-
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
-
Janowski BA, Younger ST, Hardy DB, Ram R, Huffman KE, Corey DR. Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. Nat Chem Biol. 2007;3:166-73.
-
(2007)
Nat Chem Biol.
, vol.3
, pp. 166-173
-
-
Janowski, B.A.1
Younger, S.T.2
Hardy, D.B.3
Ram, R.4
Huffman, K.E.5
Corey, D.R.6
-
111
-
-
49449117338
-
Antisense transcripts are targets for activating small RNAs
-
Schwartz JC, Younger ST, Nguyen NB, Hardy DB, Monia BP, Corey DR, et al. Antisense transcripts are targets for activating small RNAs. Nat Struct Mol Biol. 2008;15:842-8.
-
(2008)
Nat Struct Mol Biol.
, vol.15
, pp. 842-848
-
-
Schwartz, J.C.1
Younger, S.T.2
Nguyen, N.B.3
Hardy, D.B.4
Monia, B.P.5
Corey, D.R.6
-
112
-
-
84873626217
-
Long non-coding RNA targeting and transcriptional de- repression
-
Weinberg MS, Morris KV. Long non-coding RNA targeting and transcriptional de- repression. Nucleic Acid Ther. 2013;23:9-14.
-
(2013)
Nucleic Acid Ther.
, vol.23
, pp. 9-14
-
-
Weinberg, M.S.1
Morris, K.V.2
-
113
-
-
70349239135
-
Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: A novel example of epigenetherapy
-
Turunen MP, Lehtola T, Heinonen SE, Assefa GS, Korpisalo P, Girnary R, et al. Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy. Circ Res. 2009;105:604-9.
-
(2009)
Circ Res.
, vol.105
, pp. 604-609
-
-
Turunen, M.P.1
Lehtola, T.2
Heinonen, S.E.3
Assefa, G.S.4
Korpisalo, P.5
Girnary, R.6
-
114
-
-
79958859597
-
Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy
-
Perrone L, Devi TS, Hosoya KI, Terasaki T, Singh LP. Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy. Cell Death Dis. 2010;1:e65.
-
(2010)
Cell Death Dis.
, vol.1
-
-
Perrone, L.1
Devi, T.S.2
Hosoya, K.I.3
Terasaki, T.4
Singh, L.P.5
-
115
-
-
80052678741
-
Knockdown of BACE1-AS nonprotein-coding transcript modulates beta-amyloidrelated hippocampal neurogenesis
-
Modarresi F, Faghihi MA, Patel NS, Sahagan BG, Wahlestedt C, Lopez-Toledano MA. Knockdown of BACE1-AS nonprotein-coding transcript modulates beta-amyloidrelated hippocampal neurogenesis. Int J Alzheimers Dis. 2011;2011:929042.
-
(2011)
Int J Alzheimers Dis.
, vol.2011
-
-
Modarresi, F.1
Faghihi, M.A.2
Patel, N.S.3
Sahagan, B.G.4
Wahlestedt, C.5
Lopez-Toledano, M.A.6
-
116
-
-
84860353437
-
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation
-
Modarresi F, Faghihi MA, Lopez-Toledano MA, Fatemi RP, Magistri M, Brothers SP, et al. Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nat Biotechnol. 2012;30:453-9.
-
(2012)
Nat Biotechnol.
, vol.30
, pp. 453-459
-
-
Modarresi, F.1
Faghihi, M.A.2
Lopez-Toledano, M.A.3
Fatemi, R.P.4
Magistri, M.5
Brothers, S.P.6
|