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Volumn 1, Issue 8, 2014, Pages 605-617

Molecular mechanism underlying the impact of vitamin D on disease activity of MS

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON BETA SERINE; SPHINGOSINE 1 PHOSPHATE; VITAMIN D;

EID: 84924811795     PISSN: None     EISSN: 23289503     Source Type: Journal    
DOI: 10.1002/acn3.91     Document Type: Article
Times cited : (44)

References (54)
  • 1
    • 84868535570 scopus 로고    scopus 로고
    • The initiation and prevention of multiple sclerosis
    • Ascherio A, Munger KL, Lunemann JD. The initiation and prevention of multiple sclerosis. Nat Rev Neurol 2012;8:602–612.
    • (2012) Nat Rev Neurol , vol.8 , pp. 602-612
    • Ascherio, A.1    Munger, K.L.2    Lunemann, J.D.3
  • 2
    • 77951713604 scopus 로고    scopus 로고
    • Vitamin D status is associated with relapse rate in pediatric-onset multiple sclerosis
    • Mowry EM, Krupp LB, Milazzo M, et al. Vitamin D status is associated with relapse rate in pediatric-onset multiple sclerosis. Ann Neurol 2010;67:618–624.
    • (2010) Ann Neurol , vol.67 , pp. 618-624
    • Mowry, E.M.1    Krupp, L.B.2    Milazzo, M.3
  • 3
    • 84866126261 scopus 로고    scopus 로고
    • Lower serum vitamin D levels are associated with a higher relapse risk in multiple sclerosis
    • Runia TF, Hop WC, de Rijke YB, et al. Lower serum vitamin D levels are associated with a higher relapse risk in multiple sclerosis. Neurology 2012;79:261–266.
    • (2012) Neurology , vol.79 , pp. 261-266
    • Runia, T.F.1    Hop, W.C.2    de Rijke, Y.B.3
  • 4
    • 77955291052 scopus 로고    scopus 로고
    • Higher 25-hydroxyvitamin D is associated with lower relapse risk in multiple sclerosis
    • Simpson S Jr, Taylor B, Blizzard L, et al. Higher 25-hydroxyvitamin D is associated with lower relapse risk in multiple sclerosis. Ann Neurol 2010;68:193–203.
    • (2010) Ann Neurol , vol.68 , pp. 193-203
    • Simpson, S.1    Taylor, B.2    Blizzard, L.3
  • 5
    • 84865584614 scopus 로고    scopus 로고
    • Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis
    • Mowry EM, Waubant E, McCulloch CE, et al. Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis. Ann Neurol 2012;72:234–240.
    • (2012) Ann Neurol , vol.72 , pp. 234-240
    • Mowry, E.M.1    Waubant, E.2    McCulloch, C.E.3
  • 6
    • 84859612741 scopus 로고    scopus 로고
    • A randomised, double blind, placebo controlled trial with vitamin D3 as an add on treatment to interferon beta-1b in patients with multiple sclerosis
    • Soilu-Hanninen M, Aivo J, Lindstrom BM, et al. A randomised, double blind, placebo controlled trial with vitamin D3 as an add on treatment to interferon beta-1b in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry 2012;83:565–571.
    • (2012) J Neurol Neurosurg Psychiatry , vol.83 , pp. 565-571
    • Soilu-Hanninen, M.1    Aivo, J.2    Lindstrom, B.M.3
  • 7
    • 77953328331 scopus 로고    scopus 로고
    • A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis
    • Burton JM, Kimball S, Vieth R, et al. A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis. Neurology 2010;74:1852–1859.
    • (2010) Neurology , vol.74 , pp. 1852-1859
    • Burton, J.M.1    Kimball, S.2    Vieth, R.3
  • 8
    • 84860120851 scopus 로고    scopus 로고
    • Intrathecal levels of vitamin D and IgG in multiple sclerosis
    • Holmoy T, Lossius A, Gundersen TE, et al. Intrathecal levels of vitamin D and IgG in multiple sclerosis. Acta Neurol Scand 2012;125:e28–e31.
    • (2012) Acta Neurol Scand , vol.125 , pp. e28-e31
    • Holmoy, T.1    Lossius, A.2    Gundersen, T.E.3
  • 9
    • 84871190730 scopus 로고    scopus 로고
    • A systematic review of randomized, double-blind, placebo-controlled trials examining the clinical efficacy of vitamin D in multiple sclerosis
    • Pozuelo-Moyano B, Benito-Leon J, Mitchell AJ, et al. A systematic review of randomized, double-blind, placebo-controlled trials examining the clinical efficacy of vitamin D in multiple sclerosis. Neuroepidemiology 2013;40:147–153.
    • (2013) Neuroepidemiology , vol.40 , pp. 147-153
    • Pozuelo-Moyano, B.1    Benito-Leon, J.2    Mitchell, A.J.3
  • 10
    • 33749661011 scopus 로고    scopus 로고
    • Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes
    • Kappos L, Polman CH, Freedman MS, et al. Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes. Neurology 2006;67:1242–1249.
    • (2006) Neurology , vol.67 , pp. 1242-1249
    • Kappos, L.1    Polman, C.H.2    Freedman, M.S.3
  • 11
    • 34547497820 scopus 로고    scopus 로고
    • Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study
    • Kappos L, Freedman MS, Polman CH, et al. Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study. Lancet 2007;370:389–397.
    • (2007) Lancet , vol.370 , pp. 389-397
    • Kappos, L.1    Freedman, M.S.2    Polman, C.H.3
  • 12
    • 70449713830 scopus 로고    scopus 로고
    • Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial
    • Kappos L, Freedman MS, Polman CH, et al. Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial. Lancet Neurol 2009;8:987–997.
    • (2009) Lancet Neurol , vol.8 , pp. 987-997
    • Kappos, L.1    Freedman, M.S.2    Polman, C.H.3
  • 13
    • 84896765960 scopus 로고    scopus 로고
    • Vitamin D as an early predictor of multiple sclerosis activity and progression
    • Ascherio A, Munger KL, White R, et al. Vitamin D as an early predictor of multiple sclerosis activity and progression. JAMA Neurol 2014;71:306–314.
    • (2014) JAMA Neurol , vol.71 , pp. 306-314
    • Ascherio, A.1    Munger, K.L.2    White, R.3
  • 14
    • 77953943349 scopus 로고    scopus 로고
    • Vitamin D and the immune system: new perspectives on an old theme
    • Hewison M. Vitamin D and the immune system: new perspectives on an old theme. Endocrinol Metab Clin North Am 2010;39:365–379.
    • (2010) Endocrinol Metab Clin North Am , vol.39 , pp. 365-379
    • Hewison, M.1
  • 15
    • 0037122957 scopus 로고    scopus 로고
    • A longitudinal study of abnormalities on MRI and disability from multiple sclerosis
    • Brex PA, Ciccarelli O, O'Riordan JI, et al. A longitudinal study of abnormalities on MRI and disability from multiple sclerosis. N Engl J Med 2002;346:158–164.
    • (2002) N Engl J Med , vol.346 , pp. 158-164
    • Brex, P.A.1    Ciccarelli, O.2    O'Riordan, J.I.3
  • 16
    • 84893569616 scopus 로고    scopus 로고
    • Interferon beta-1b reduces black holes in a randomised trial of clinically isolated syndrome
    • Nagtegaal GJ, Pohl C, Wattjes MP, et al. Interferon beta-1b reduces black holes in a randomised trial of clinically isolated syndrome. Mult Scler 2014;20:234–242.
    • (2014) Mult Scler , vol.20 , pp. 234-242
    • Nagtegaal, G.J.1    Pohl, C.2    Wattjes, M.P.3
  • 18
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    • Bolstad BM, Irizarry RA, Astrand M, et al. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 2003;19:185–193.
    • (2003) Bioinformatics , vol.19 , pp. 185-193
    • Bolstad, B.M.1    Irizarry, R.A.2    Astrand, M.3
  • 19
    • 29144535372 scopus 로고    scopus 로고
    • Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
    • Dai M, Wang P, Boyd AD, et al. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res 2005;33:e175.
    • (2005) Nucleic Acids Res , vol.33
    • Dai, M.1    Wang, P.2    Boyd, A.D.3
  • 20
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc 1995;51:289–300.
    • (1995) J R Stat Soc , vol.51 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 22
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005;102:15545–15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 23
    • 82255185583 scopus 로고    scopus 로고
    • Nuclear hormone 1alpha,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy
    • Heikkinen S, Vaisanen S, Pehkonen P, et al. Nuclear hormone 1alpha,25-dihydroxyvitamin D3 elicits a genome-wide shift in the locations of VDR chromatin occupancy. Nucleic Acids Res 2011;39:9181–9193.
    • (2011) Nucleic Acids Res , vol.39 , pp. 9181-9193
    • Heikkinen, S.1    Vaisanen, S.2    Pehkonen, P.3
  • 24
    • 77956885532 scopus 로고    scopus 로고
    • A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution
    • Ramagopalan SV, Heger A, Berlanga AJ, et al. A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. Genome Res 2010;20:1352–1360.
    • (2010) Genome Res , vol.20 , pp. 1352-1360
    • Ramagopalan, S.V.1    Heger, A.2    Berlanga, A.J.3
  • 25
    • 0038005018 scopus 로고    scopus 로고
    • DAVID: Database for Annotation, Visualization, and Integrated Discovery
    • Dennis G Jr, Sherman BT, Hosack DA, et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol 2003;4:3.
    • (2003) Genome Biol , vol.4 , pp. 3
    • Dennis, G.1    Sherman, B.T.2    Hosack, D.A.3
  • 26
    • 67849122320 scopus 로고    scopus 로고
    • MEME SUITE: tools for motif discovery and searching
    • Bailey TL, Boden M, Buske FA, et al. MEME SUITE: tools for motif discovery and searching. Nucleic Acids Res 2009;37:W202–W208.
    • (2009) Nucleic Acids Res , vol.37 , pp. W202-W208
    • Bailey, T.L.1    Boden, M.2    Buske, F.A.3
  • 27
    • 38549096565 scopus 로고    scopus 로고
    • JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update
    • Bryne JC, Valen E, Tang MH, et al. JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update. Nucleic Acids Res 2008;36:D102–D106.
    • (2008) Nucleic Acids Res , vol.36 , pp. D102-D106
    • Bryne, J.C.1    Valen, E.2    Tang, M.H.3
  • 28
    • 0023987751 scopus 로고
    • Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control
    • Levy DE, Kessler DS, Pine R, et al. Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control. Genes Dev 1988;2:383–393.
    • (1988) Genes Dev , vol.2 , pp. 383-393
    • Levy, D.E.1    Kessler, D.S.2    Pine, R.3
  • 29
    • 77954864204 scopus 로고    scopus 로고
    • Fingolimod is a potential novel therapy for multiple sclerosis
    • Aktas O, Kury P, Kieseier B, et al. Fingolimod is a potential novel therapy for multiple sclerosis. Nat Rev Neurol 2010;6:373–382.
    • (2010) Nat Rev Neurol , vol.6 , pp. 373-382
    • Aktas, O.1    Kury, P.2    Kieseier, B.3
  • 30
    • 79952026310 scopus 로고    scopus 로고
    • Clinical immunology of the sphingosine 1-phosphate receptor modulator fingolimod (FTY720) in multiple sclerosis
    • Mehling M, Johnson TA, Antel J, et al. Clinical immunology of the sphingosine 1-phosphate receptor modulator fingolimod (FTY720) in multiple sclerosis. Neurology 2011;76:S20–S27.
    • (2011) Neurology , vol.76 , pp. S20-S27
    • Mehling, M.1    Johnson, T.A.2    Antel, J.3
  • 31
    • 84880008405 scopus 로고    scopus 로고
    • Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease
    • Handel AE, Sandve GK, Disanto G, et al. Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease. BMC Med 2013;11:163.
    • (2013) BMC Med , vol.11 , pp. 163
    • Handel, A.E.1    Sandve, G.K.2    Disanto, G.3
  • 32
    • 33751537194 scopus 로고    scopus 로고
    • Minireview: vitamin D receptor: new assignments for an already busy receptor
    • Norman AW. Minireview: vitamin D receptor: new assignments for an already busy receptor. Endocrinology 2006;147:5542–5548.
    • (2006) Endocrinology , vol.147 , pp. 5542-5548
    • Norman, A.W.1
  • 33
    • 57449109161 scopus 로고    scopus 로고
    • A vitamin D nutritional cornucopia: new insights concerning the serum 25-hydroxyvitamin D status of the US population
    • Norman AW. A vitamin D nutritional cornucopia: new insights concerning the serum 25-hydroxyvitamin D status of the US population. Am J Clin Nutr 2008;88:1455–1456.
    • (2008) Am J Clin Nutr , vol.88 , pp. 1455-1456
    • Norman, A.W.1
  • 34
    • 77649298024 scopus 로고    scopus 로고
    • Modulation of the vitamin D3 response by cancer-associated mutant p53
    • Stambolsky P, Tabach Y, Fontemaggi G, et al. Modulation of the vitamin D3 response by cancer-associated mutant p53. Cancer Cell 2010;17:273–285.
    • (2010) Cancer Cell , vol.17 , pp. 273-285
    • Stambolsky, P.1    Tabach, Y.2    Fontemaggi, G.3
  • 35
    • 34447514029 scopus 로고    scopus 로고
    • Vitamin D deficiency
    • Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266–281.
    • (2007) N Engl J Med , vol.357 , pp. 266-281
    • Holick, M.F.1
  • 36
    • 84871982871 scopus 로고    scopus 로고
    • Accessed 1 June 2014
    • Broad Institute. Gene set enrichment analysis: GSEA user guide. Available at http://www.broadinstitute.org/gsea/GSEAUserGuide.pdf. Accessed 1 June 2014.
    • Gene set enrichment analysis: GSEA user guide
  • 37
    • 84876515907 scopus 로고    scopus 로고
    • STRING v9.1: protein-protein interaction networks, with increased coverage and integration
    • Franceschini A, Szklarczyk D, Frankild S, et al. STRING v9.1: protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res 2013;41:D808–D815.
    • (2013) Nucleic Acids Res , vol.41 , pp. D808-D815
    • Franceschini, A.1    Szklarczyk, D.2    Frankild, S.3
  • 38
    • 84861414827 scopus 로고    scopus 로고
    • Lactoferrin, a key molecule in immune and inflammatory processes
    • Legrand D. Lactoferrin, a key molecule in immune and inflammatory processes. Biochem Cell Biol 2012;90:252–268.
    • (2012) Biochem Cell Biol , vol.90 , pp. 252-268
    • Legrand, D.1
  • 39
    • 0033961106 scopus 로고    scopus 로고
    • Seasonal fluctuations of gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis
    • Auer DP, Schumann EM, Kumpfel T, et al. Seasonal fluctuations of gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis. Ann Neurol 2000;47:276–277.
    • (2000) Ann Neurol , vol.47 , pp. 276-277
    • Auer, D.P.1    Schumann, E.M.2    Kumpfel, T.3
  • 40
    • 0037046194 scopus 로고    scopus 로고
    • Seasonal variation in immune measurements and MRI markers of disease activity in MS
    • Killestein J, Rep MH, Meilof JF, et al. Seasonal variation in immune measurements and MRI markers of disease activity in MS. Neurology 2002;58:1077–1080.
    • (2002) Neurology , vol.58 , pp. 1077-1080
    • Killestein, J.1    Rep, M.H.2    Meilof, J.F.3
  • 41
    • 0035097505 scopus 로고    scopus 로고
    • Effects of seasons on magnetic resonance imaging-measured disease activity in patients with multiple sclerosis
    • Rovaris M, Comi G, Sormani MP, et al. Effects of seasons on magnetic resonance imaging-measured disease activity in patients with multiple sclerosis. Ann Neurol 2001;49:415–416.
    • (2001) Ann Neurol , vol.49 , pp. 415-416
    • Rovaris, M.1    Comi, G.2    Sormani, M.P.3
  • 42
    • 79957994942 scopus 로고    scopus 로고
    • Vitamin D-related gene expression profiles in immune cells of patients with relapsing remitting multiple sclerosis
    • Smolders J, Thewissen M, Theunissen R, et al. Vitamin D-related gene expression profiles in immune cells of patients with relapsing remitting multiple sclerosis. J Neuroimmunol 2011;235:91–97.
    • (2011) J Neuroimmunol , vol.235 , pp. 91-97
    • Smolders, J.1    Thewissen, M.2    Theunissen, R.3
  • 43
    • 84872844760 scopus 로고    scopus 로고
    • Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue
    • Smolders J, Schuurman KG, van Strien ME, et al. Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue. J Neuropathol Exp Neurol 2013;72:91–105.
    • (2013) J Neuropathol Exp Neurol , vol.72 , pp. 91-105
    • Smolders, J.1    Schuurman, K.G.2    van Strien, M.E.3
  • 44
    • 72649106903 scopus 로고    scopus 로고
    • A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis
    • Comabella M, Lunemann JD, Rio J, et al. A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis. Brain 2009;132:3353–3365.
    • (2009) Brain , vol.132 , pp. 3353-3365
    • Comabella, M.1    Lunemann, J.D.2    Rio, J.3
  • 45
    • 77953524192 scopus 로고    scopus 로고
    • The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis
    • Gandhi KS, McKay FC, Cox M, et al. The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis. Hum Mol Genet 2010;19:2134–2143.
    • (2010) Hum Mol Genet , vol.19 , pp. 2134-2143
    • Gandhi, K.S.1    McKay, F.C.2    Cox, M.3
  • 46
    • 84884713934 scopus 로고    scopus 로고
    • Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls
    • Nickles D, Chen HP, Li MM, et al. Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls. Hum Mol Genet 2013;22:4194–4205.
    • (2013) Hum Mol Genet , vol.22 , pp. 4194-4205
    • Nickles, D.1    Chen, H.P.2    Li, M.M.3
  • 47
    • 33748295732 scopus 로고    scopus 로고
    • A subtype of multiple sclerosis defined by an activated immune defense program
    • van Baarsen LG, van der Pouw Kraan TC, Kragt JJ, et al. A subtype of multiple sclerosis defined by an activated immune defense program. Genes Immun 2006;7:522–531.
    • (2006) Genes Immun , vol.7 , pp. 522-531
    • van Baarsen, L.G.1    van der Pouw Kraan, T.C.2    Kragt, J.J.3
  • 48
    • 0035912520 scopus 로고    scopus 로고
    • Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study
    • Comi G, Filippi M, Barkhof F, et al. Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study. Lancet 2001;357:1576–1582.
    • (2001) Lancet , vol.357 , pp. 1576-1582
    • Comi, G.1    Filippi, M.2    Barkhof, F.3
  • 49
    • 84884587008 scopus 로고    scopus 로고
    • Interferon-beta-1b-induced short- and long-term signatures of treatment activity in multiple sclerosis
    • Croze E, Yamaguchi KD, Knappertz V, et al. Interferon-beta-1b-induced short- and long-term signatures of treatment activity in multiple sclerosis. Pharmacogenomics J 2013;13:443–451.
    • (2013) Pharmacogenomics J , vol.13 , pp. 443-451
    • Croze, E.1    Yamaguchi, K.D.2    Knappertz, V.3
  • 50
    • 44849128066 scopus 로고    scopus 로고
    • Pharmacogenomics of interferon-beta therapy in multiple sclerosis: baseline IFN signature determines pharmacological differences between patients
    • van Baarsen LG, Vosslamber S, Tijssen M, et al. Pharmacogenomics of interferon-beta therapy in multiple sclerosis: baseline IFN signature determines pharmacological differences between patients. PLoS One 2008;3:e1927.
    • (2008) PLoS One , vol.3
    • van Baarsen, L.G.1    Vosslamber, S.2    Tijssen, M.3
  • 51
    • 84879768723 scopus 로고    scopus 로고
    • Molecular network of chromatin immunoprecipitation followed by deep sequencing-based vitamin D receptor target genes
    • Satoh J, Tabunoki H. Molecular network of chromatin immunoprecipitation followed by deep sequencing-based vitamin D receptor target genes. Mult Scler 2013;19:1035–1045.
    • (2013) Mult Scler , vol.19 , pp. 1035-1045
    • Satoh, J.1    Tabunoki, H.2
  • 52
    • 0022407280 scopus 로고
    • Regulation of 1,25-dihydroxyvitamin D3 receptors by vitamin D analogs in cultured mammalian cells
    • Costa EM, Hirst MA, Feldman D. Regulation of 1,25-dihydroxyvitamin D3 receptors by vitamin D analogs in cultured mammalian cells. Endocrinology 1985;117:2203–2210.
    • (1985) Endocrinology , vol.117 , pp. 2203-2210
    • Costa, E.M.1    Hirst, M.A.2    Feldman, D.3
  • 53
    • 8544284075 scopus 로고    scopus 로고
    • Enzymes involved in the activation and inactivation of vitamin D
    • Prosser DE, Jones G. Enzymes involved in the activation and inactivation of vitamin D. Trends Biochem Sci 2004;29:664–673.
    • (2004) Trends Biochem Sci , vol.29 , pp. 664-673
    • Prosser, D.E.1    Jones, G.2
  • 54
    • 0028945042 scopus 로고
    • Two vitamin D response elements function in the rat 1,25-dihydroxyvitamin D 24-hydroxylase promoter
    • Zierold C, Darwish HM, DeLuca HF. Two vitamin D response elements function in the rat 1,25-dihydroxyvitamin D 24-hydroxylase promoter. J Biol Chem 1995;270:1675–1678.
    • (1995) J Biol Chem , vol.270 , pp. 1675-1678
    • Zierold, C.1    Darwish, H.M.2    DeLuca, H.F.3


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