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Volumn 7, Issue 6, 2006, Pages 522-531

A subtype of multiple sclerosis defined by an activated immune defense program

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; COMPLEMENTARY DNA; DISEASE MODIFYING ANTIRHEUMATIC DRUG;

EID: 33748295732     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/sj.gene.6364324     Document Type: Article
Times cited : (80)

References (52)
  • 1
    • 2142662186 scopus 로고    scopus 로고
    • Multiple sclerosis
    • Hafler DA. Multiple sclerosis. J Clin Invest 2004; 113: 788-794.
    • (2004) J Clin Invest , vol.113 , pp. 788-794
    • Hafler, D.A.1
  • 2
    • 0036789860 scopus 로고    scopus 로고
    • Assessment of different treatment failure criteria in a cohort of relapsing-remitting multiple sclerosis patients treated with interferon beta: Implications for clinical trials
    • Rio J, Nos C, Tintore M, Borras C, Galan I, Comabella M et al. Assessment of different treatment failure criteria in a cohort of relapsing-remitting multiple sclerosis patients treated with interferon beta: Implications for clinical trials. Ann Neurol 2002; 52: 400-406.
    • (2002) Ann Neurol , vol.52 , pp. 400-406
    • Rio, J.1    Nos, C.2    Tintore, M.3    Borras, C.4    Galan, I.5    Comabella, M.6
  • 3
    • 0342906187 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
    • Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination. Ann Neurol 2000; 47: 707-717.
    • (2000) Ann Neurol , vol.47 , pp. 707-717
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 7
    • 0002830396 scopus 로고    scopus 로고
    • Epidemiology of MS
    • In: Hallpike JF, Adams CWM, Tourtellote WE (eds). Willimas and Wilkins: Baltimore, MD
    • Kurtzke JF. Epidemiology of MS. In: Hallpike JF, Adams CWM, Tourtellote WE (eds). Multiple Sclerosis. Willimas and Wilkins: Baltimore, MD, 2005, pp. 49-95.
    • (2005) Multiple Sclerosis , pp. 49-95
    • Kurtzke, J.F.1
  • 8
    • 0001194782 scopus 로고    scopus 로고
    • The proposed viral etiology of multiple sclerosis and related demyelinating diseases
    • In: Raine CS, MacFarland HF, Tourtellotte WW (eds). Chapman & Hall: London
    • Ter Meulen V, Katz M. The proposed viral etiology of multiple sclerosis and related demyelinating diseases. In: Raine CS, MacFarland HF, Tourtellotte WW (eds). Multiple Sclerosis. Chapman & Hall: London, 1997, pp. 287-305.
    • (1997) Multiple Sclerosis , pp. 287-305
    • Ter Meulen, V.1    Katz, M.2
  • 9
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 2001; 98: 5116-5121.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 10
    • 0034283844 scopus 로고    scopus 로고
    • Transcription, genomes, function
    • Cho RJ, Campbell MJ. Transcription, genomes, function. Trends Genet 2000; 16: 409-415.
    • (2000) Trends Genet , vol.16 , pp. 409-415
    • Cho, R.J.1    Campbell, M.J.2
  • 12
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005; 102: 15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5    Gillette, M.A.6
  • 13
    • 15944395145 scopus 로고    scopus 로고
    • Insights into host responses against pathogens from transcriptional profiling
    • Jenner RG, Young RA. Insights into host responses against pathogens from transcriptional profiling. Nat Rev Microbiol 2005; 3: 281-294.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 281-294
    • Jenner, R.G.1    Young, R.A.2
  • 14
    • 0034767753 scopus 로고    scopus 로고
    • Antiviral actions of interferons
    • Table
    • Samuel CE. Antiviral actions of interferons. Clin Microbiol Rev 2001; 14: 778-809, Table.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 778-809
    • Samuel, C.E.1
  • 15
    • 23744454577 scopus 로고    scopus 로고
    • TLR signalling and activation of IRFs: Revisiting old friends from the NF-kappaB pathway
    • Moynagh PN. TLR signalling and activation of IRFs: Revisiting old friends from the NF-kappaB pathway. Trends Immunol 2005; 26: 469-476.
    • (2005) Trends Immunol , vol.26 , pp. 469-476
    • Moynagh, P.N.1
  • 16
    • 6344276562 scopus 로고    scopus 로고
    • The host response to smallpox: Analysis of the gene expression program in peripheral blood cells in a nonhuman primate model
    • Rubins KH, Hensley LE, Jahrling PB, Whitney AR, Geisbert TW, Huggins JW et al. The host response to smallpox: Analysis of the gene expression program in peripheral blood cells in a nonhuman primate model. Proc Natl Acad Sci USA 2004; 101: 15190-15195.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15190-15195
    • Rubins, K.H.1    Hensley, L.E.2    Jahrling, P.B.3    Whitney, A.R.4    Geisbert, T.W.5    Huggins, J.W.6
  • 17
    • 1442304886 scopus 로고    scopus 로고
    • Blood transcriptional signatures of multiple sclerosis: Unique gene expression of disease activity
    • Achiron A, Gurevich M, Friedman N, Kaminski N, Mandel M. Blood transcriptional signatures of multiple sclerosis: Unique gene expression of disease activity. Ann Neurol 2004; 55: 410-417.
    • (2004) Ann Neurol , vol.55 , pp. 410-417
    • Achiron, A.1    Gurevich, M.2    Friedman, N.3    Kaminski, N.4    Mandel, M.5
  • 18
    • 0042976370 scopus 로고    scopus 로고
    • Gene expression profiles in human autoimmune disease
    • Aune TM, Maas K, Moore JH, Olsen NJ. Gene expression profiles in human autoimmune disease. Curr Pharm Des 2003; 9: 1905-1917.
    • (2003) Curr Pharm Des , vol.9 , pp. 1905-1917
    • Aune, T.M.1    Maas, K.2    Moore, J.H.3    Olsen, N.J.4
  • 19
    • 0036644048 scopus 로고    scopus 로고
    • Cutting edge: Molecular portrait of human autoimmune disease
    • Maas K, Chan S, Parker J, Slater A, Moore J, Olsen N et al. Cutting edge: Molecular portrait of human autoimmune disease. J Immunol 2002; 169: 5-9.
    • (2002) J Immunol , vol.169 , pp. 5-9
    • Maas, K.1    Chan, S.2    Parker, J.3    Slater, A.4    Moore, J.5    Olsen, N.6
  • 20
    • 4644343950 scopus 로고    scopus 로고
    • Autoimmunity gene expression portrait: Specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus
    • Mandel M, Gurevich M, Pauzner R, Kaminski N, Achiron A. Autoimmunity gene expression portrait: Specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus. Clin Exp Immunol 2004; 138: 164-170.
    • (2004) Clin Exp Immunol , vol.138 , pp. 164-170
    • Mandel, M.1    Gurevich, M.2    Pauzner, R.3    Kaminski, N.4    Achiron, A.5
  • 21
    • 20044383560 scopus 로고    scopus 로고
    • Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis
    • Satoh J, Nakanishi M, Koike F, Miyake S, Yamamoto T, Kawai M et al. Microarray analysis identifies an aberrant expression of apoptosis and DNA damage-regulatory genes in multiple sclerosis. Neurobiol Dis 2005; 18: 537-550.
    • (2005) Neurobiol Dis , vol.18 , pp. 537-550
    • Satoh, J.1    Nakanishi, M.2    Koike, F.3    Miyake, S.4    Yamamoto, T.5    Kawai, M.6
  • 22
    • 21644464144 scopus 로고    scopus 로고
    • Role of oxidative damage in the pathogenesis of viral infections of the nervous system
    • Valyi-Nagy T, Dermody TS. Role of oxidative damage in the pathogenesis of viral infections of the nervous system. Histol Histopathol 2005; 20: 957-967.
    • (2005) Histol Histopathol , vol.20 , pp. 957-967
    • Valyi-Nagy, T.1    Dermody, T.S.2
  • 23
    • 4344591766 scopus 로고    scopus 로고
    • Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene
    • Hultqvist M, Olofsson P, Holmberg J, Backstrom BT, Tordsson J, Holmdahl R. Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene. Proc Natl Acad Sci USA 2004; 101: 12646-12651.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 12646-12651
    • Hultqvist, M.1    Olofsson, P.2    Holmberg, J.3    Backstrom, B.T.4    Tordsson, J.5    Holmdahl, R.6
  • 24
    • 0029135283 scopus 로고
    • Mechanism of interferon action: Double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons
    • Patterson JB, Thomis DC, Hans SL, Samuel CE. Mechanism of interferon action: Double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons. Virology 1995; 210: 508-511.
    • (1995) Virology , vol.210 , pp. 508-511
    • Patterson, J.B.1    Thomis, D.C.2    Hans, S.L.3    Samuel, C.E.4
  • 25
    • 0028574351 scopus 로고
    • Control of kinetic properties of AMPA receptor channels by nuclear RNA editing
    • Lomeli H, Mosbacher J, Melcher T, Hoger T, Geiger JR, Kuner T et al. Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. Science 1994; 266: 1709-1713.
    • (1994) Science , vol.266 , pp. 1709-1713
    • Lomeli, H.1    Mosbacher, J.2    Melcher, T.3    Hoger, T.4    Geiger, J.R.5    Kuner, T.6
  • 26
    • 0032079356 scopus 로고    scopus 로고
    • The 2-5A system: Modulation of viral and cellular processes through acceleration of RNA degradation
    • Player MR, Torrence PF. The 2-5A system: Modulation of viral and cellular processes through acceleration of RNA degradation. Pharmacol Ther 1998; 78: 55-113.
    • (1998) Pharmacol Ther , vol.78 , pp. 55-113
    • Player, M.R.1    Torrence, P.F.2
  • 27
    • 4744357399 scopus 로고    scopus 로고
    • Missorting of LaCrosse virus nucleocapsid protein by the interferon-induced MxA GTPase involves smooth ER membranes
    • Reichelt M, Stertz S, Krijnse-Locker J, Haller O, Kochs G. Missorting of LaCrosse virus nucleocapsid protein by the interferon-induced MxA GTPase involves smooth ER membranes. Traffic 2004; 5: 772-784.
    • (2004) Traffic , vol.5 , pp. 772-784
    • Reichelt, M.1    Stertz, S.2    Krijnse-Locker, J.3    Haller, O.4    Kochs, G.5
  • 28
    • 0027372154 scopus 로고
    • Function of the mouse Mx1 protein is inhibited by overexpression of the PB2 protein of influenza virus
    • Stranden AM, Staeheli P, Pavlovic J. Function of the mouse Mx1 protein is inhibited by overexpression of the PB2 protein of influenza virus. Virology 1993; 197: 642-651.
    • (1993) Virology , vol.197 , pp. 642-651
    • Stranden, A.M.1    Staeheli, P.2    Pavlovic, J.3
  • 29
    • 0034867420 scopus 로고    scopus 로고
    • Increased levels of antiviral MxA protein in peripheral blood of patients with a chronic disease of unknown etiology
    • Chieux V, Chehadeh W, Hautecoeur P, Harvey J, Wattre P, Hober D. Increased levels of antiviral MxA protein in peripheral blood of patients with a chronic disease of unknown etiology. J Med Virol 2001; 65: 301-308.
    • (2001) J Med Virol , vol.65 , pp. 301-308
    • Chieux, V.1    Chehadeh, W.2    Hautecoeur, P.3    Harvey, J.4    Wattre, P.5    Hober, D.6
  • 31
    • 33748295391 scopus 로고    scopus 로고
    • Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: Assignement of a type I interferon signature in a subpopulation of patients
    • (submitted for publication)
    • van der Pouw Kraan CTM, Wijbrandts CA, van Baarsen LGM, Voskuyl AE, Rustenburg F, Baggen JM et al. Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: Assignement of a type I interferon signature in a subpopulation of patients (submitted for publication).
    • van der Pouw Kraan, C.T.M.1    Wijbrandts, C.A.2    van Baarsen, L.G.M.3    Voskuyl, A.E.4    Rustenburg, F.5    Baggen, J.M.6
  • 32
    • 17244372491 scopus 로고    scopus 로고
    • Activation of the type I interferon system in primary Sjogren's syndrome: A possible etiopathogenic mechanism
    • Bave U, Nordmark G, Lovgren T, Ronnelid J, Cajander S, Eloranta ML et al. Activation of the type I interferon system in primary Sjogren's syndrome: A possible etiopathogenic mechanism. Arthritis Rheum 2005; 52: 1185-1195.
    • (2005) Arthritis Rheum , vol.52 , pp. 1185-1195
    • Bave, U.1    Nordmark, G.2    Lovgren, T.3    Ronnelid, J.4    Cajander, S.5    Eloranta, M.L.6
  • 33
    • 0029036567 scopus 로고
    • Interferon expression in the pancreases of patients with type I diabetes
    • Huang X, Yuang J, Goddard A, Foulis A, James RF, Lernmark A et al. Interferon expression in the pancreases of patients with type I diabetes. Diabetes 1995; 44: 658-664.
    • (1995) Diabetes , vol.44 , pp. 658-664
    • Huang, X.1    Yuang, J.2    Goddard, A.3    Foulis, A.4    James, R.F.5    Lernmark, A.6
  • 35
    • 0034533825 scopus 로고    scopus 로고
    • Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
    • Bengtsson AA, Sturfelt G, Truedsson L, Blomberg J, Alm G, Vallin H et al. Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies. Lupus 2000; 9: 664-671.
    • (2000) Lupus , vol.9 , pp. 664-671
    • Bengtsson, A.A.1    Sturfelt, G.2    Truedsson, L.3    Blomberg, J.4    Alm, G.5    Vallin, H.6
  • 36
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4: 499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 37
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004; 5: 730-737.
    • (2004) Nat Immunol , vol.5 , pp. 730-737
    • Yoneyama, M.1    Kikuchi, M.2    Natsukawa, T.3    Shinobu, N.4    Imaizumi, T.5    Miyagishi, M.6
  • 38
    • 0034212893 scopus 로고    scopus 로고
    • Mistaken self, a novel model that links microbial infections with myelin-directed autoimmunity in multiple sclerosis
    • van Noort JM, Bajramovic JJ, Plomp AC, van Stipdonk MJ. Mistaken self, a novel model that links microbial infections with myelin-directed autoimmunity in multiple sclerosis. J Neuroimmunol 2000; 105: 46-57.
    • (2000) J Neuroimmunol , vol.105 , pp. 46-57
    • van Noort, J.M.1    Bajramovic, J.J.2    Plomp, A.C.3    van Stipdonk, M.J.4
  • 39
    • 2642528779 scopus 로고    scopus 로고
    • Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG
    • Lovgren T, Eloranta ML, Bave U, Alm GV, Ronnblom L. Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum 2004; 50: 1861-1872.
    • (2004) Arthritis Rheum , vol.50 , pp. 1861-1872
    • Lovgren, T.1    Eloranta, M.L.2    Bave, U.3    Alm, G.V.4    Ronnblom, L.5
  • 41
    • 0038546727 scopus 로고    scopus 로고
    • Microarray analysis identifies interferon beta-regulated genes in multiple sclerosis
    • Koike F, Satoh J, Miyake S, Yamamoto T, Kawai M, Kikuchi S et al. Microarray analysis identifies interferon beta-regulated genes in multiple sclerosis. J Neuroimmunol 2003; 139: 109-118.
    • (2003) J Neuroimmunol , vol.139 , pp. 109-118
    • Koike, F.1    Satoh, J.2    Miyake, S.3    Yamamoto, T.4    Kawai, M.5    Kikuchi, S.6
  • 43
    • 0038692013 scopus 로고    scopus 로고
    • Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis
    • Sturzebecher S, Wandinger KP, Rosenwald A, Sathyamoorthy M, Tzou A, Mattar P et al. Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis. Brain 2003; 126: 1419-1429.
    • (2003) Brain , vol.126 , pp. 1419-1429
    • Sturzebecher, S.1    Wandinger, K.P.2    Rosenwald, A.3    Sathyamoorthy, M.4    Tzou, A.5    Mattar, P.6
  • 44
    • 0034955141 scopus 로고    scopus 로고
    • Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
    • McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD et al. Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001; 50: 121-127.
    • (2001) Ann Neurol , vol.50 , pp. 121-127
    • McDonald, W.I.1    Compston, A.2    Edan, G.3    Goodkin, D.4    Hartung, H.P.5    Lublin, F.D.6
  • 45
    • 33748292696 scopus 로고    scopus 로고
    • Gene expression profiling in rheumatology
    • In: Cope A (ed). Medicine The Humana Press Inc.: Totowa, NJ
    • van der Pouw Kraan TC, Baarsen EGM, Rustenburg F et al. Gene expression profiling in rheumatology. In: Cope A (ed). Methods in Molecular Medicine. The Humana Press Inc.: Totowa, NJ, 2005.
    • (2005) Methods in Molecular
    • van der Pouw Kraan, T.C.1    Baarsen, E.G.M.2    Rustenburg, F.3
  • 48
    • 13444282425 scopus 로고    scopus 로고
    • The standard microarray database accommodates additional microarray platforms and data formats
    • (Database issue):
    • Ball CA, Awad IA, Demeter J, Gollub J, Hebert JM, Hernandez-Boussard T et al. The standard microarray database accommodates additional microarray platforms and data formats. Nucleic Acids Res 2005; 33 (Database issue): D580-D582.
    • (2005) Nucleic Acids Res , vol.33
    • Ball, C.A.1    Awad, I.A.2    Demeter, J.3    Gollub, J.4    Hebert, J.M.5    Hernandez-Boussard, T.6
  • 49
    • 1342294092 scopus 로고    scopus 로고
    • Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation
    • Yang YH, Dudoit S, Luu P, Lin DM, Peng V, Ngai J et al. Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 2002; 30: E15.
    • (2002) Nucleic Acids Res , vol.30
    • Yang, Y.H.1    Dudoit, S.2    Luu, P.3    Lin, D.M.4    Peng, V.5    Ngai, J.6
  • 52
    • 0038054341 scopus 로고    scopus 로고
    • PGC-lalpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
    • Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J et al. PGC-lalpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003; 34: 267-273.
    • (2003) Nat Genet , vol.34 , pp. 267-273
    • Mootha, V.K.1    Lindgren, C.M.2    Eriksson, K.F.3    Subramanian, A.4    Sihag, S.5    Lehar, J.6


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