HMGB1 gene polymorphism is associated with hypertension in Han Chinese population

Clinical and Experimental Hypertension

Volumn 37, Issue 2, 2015, Pages 166-171

  Yao, Yingshui ^a   Guo, Daoxia ^a   Yang, Song ^b   Jin, Yuelong ^a   He, Lianping ^a   Chen, Jinfeng ^c   Zhao, Xianghai ^b   Chen, Yanchun ^b   Zhou, Wei ^b   Shen, Chong ^c  

^a WANNAN MEDICAL COLLEGE   (China)

^b YIXING PEOPLE S HOSPITAL   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Association study; HMGB1; Hypertension

Indexed keywords

C REACTIVE PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; DNA;

ADULT; AGE DISTRIBUTION; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HAN CHINESE; HAPLOTYPE; HMGB1 GENE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PATHOGENESIS; POPULATION; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; AGE; BLOOD PRESSURE; CHINA; CLINICAL TRIAL; EPIDEMIOLOGY; ETHNIC GROUP; ETHNOLOGY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PREVALENCE; RETROSPECTIVE STUDY; RISK FACTOR; RURAL POPULATION;

AGE FACTORS; BLOOD PRESSURE; CHINA; DNA; ETHNIC GROUPS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HMGB1 PROTEIN; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PREVALENCE; RETROSPECTIVE STUDIES; RISK FACTORS; RURAL POPULATION;

EID: 84924810347     PISSN: 10641963     EISSN: 15256006     Source Type: Journal    
DOI: 10.3109/10641963.2014.933963     Document Type: Article

References (42)

1. He J, Gu D, Wu X, et al. Major causes of death among men and women in China. N Engl J Med 2005;353:1124-34.
2. Kannel WB, Schwartz MJ, McNamara PM. Blood pressure and risk of coronary heart disease: the Framingham study. Dis Chest 1969; 56:43-52.
3. Staessen JA, Wang J, Bianchi G, et al. Essential hypertension. Lancet 2003;361:1629-41.
4. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999;340:115-26.
5. Fiuza C, Bustin M, Talwar S, et al. Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells. Blood 2003;101:2652-60.
6. Treutiger CJ, Mullins GE, Johansson AS, et al. High mobility group 1 B-box mediates activation of human endothelium. J Intern Med 2003;254:375-85.
7. Schmidt AM, Yan SD, Yan SF, Stern DM. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J Clin Invest 2001;108:949-55.
8. Yan SF, Ramasamy R, Schmidt AM. Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response. J Mol Med (Berl) 2009;87:235-47.
9. Yao D, Brownlee M. Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands. Diabetes 2010;59: 249-55.
10. Zhao Y, Wang H, Liu S, et al. Association study of CRP gene polymorphism and hypertension in Han Chinese population. Gene 2013;512:41-6.
11. Foell D, Wittkowski H, Roth J. Mechanisms of disease: a 'DAMP' view of inflammatory arthritis. Nat Clin Pract Rheumatol 2007;3: 382-90.
12. Rubartelli A, Lotze MT. Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox. Trends Immunol 2007;28:429-36.
13. Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 2007;81:1-5.
14. Read CM, Cary PD, Crane-Robinson C, et al. Solution structure of a DNA-binding domain from HMG1. Nucleic Acids Res 1993;21: 3427-36.
15. Javaherian K, Liu JF, Wang JC. Nonhistone proteins HMG1 and HMG2 change the DNA helical structure. Science 1978;199: 1345-6.
16. Wang H, Bloom O, Zhang M, et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 1999;285:248-51.
17. Lu B, Nakamura T, Inouye K, et al. Novel role of PKR in inflammasome activation and HMGB1 release. Nature 2012;488: 670-4.
18. Park JS, Svetkauskaite D, He Q, et al. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2004;279:7370-7.
19. Hori O, Brett J, Slattery T, et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 1995;270:25752-61.
20. Yan XX, Lu L, Peng WH, et al. Increased serum HMGB1 level is associated with coronary artery disease in nondiabetic and type 2 diabetic patients. Atherosclerosis 2009;205:544-8.
21. Yang D, Chen Q, Yang H, et al. High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin. J Leukoc Biol 2007;81:59-66.
22. Hreggvidsdottir HS, Lundberg AM, Aveberger AC, et al. High mobility group box protein 1 (HMGB1)-partner molecule complexes enhance cytokine production by signaling through the partner molecule receptor. Mol Med 2012;18:224-30.
23. de Souza AW, Westra J, Limburg PC, et al. HMGB1 in vascular diseases: its role in vascular inflammation and atherosclerosis. Autoimmun Rev 2012;11:909-17.
24. Xu H, Yao Y, Su Z, et al. Endogenous HMGB1 contributes to ischemia-reperfusion-induced myocardial apoptosis by potentiating the effect of TNF-a/JNK. Am J Physiol Heart Circ Physiol 2011; 300:H913-21.
25. Andrassy M, Volz HC, Igwe JC, et al. High-mobility group box-1 in ischemia-reperfusion injury of the heart. Circulation 2008;117: 3216-26.
26. Kitahara T, Takeishi Y, Harada M, et al. High-mobility group box 1 restores cardiac function after myocardial infarction in transgenic mice. Cardiovasc Res 2008;80:40-6.
27. Limana F, Germani A, Zacheo A, et al. Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit + cell proliferation and differentiation. Circ Res 2005;97:e73-83.
28. Takahashi K, Fukushima S, Yamahara K, et al. Modulated inflammation by injection of high-mobility group box 1 recovers post-infarction chronically failing heart. Circulation 2008;118: S106-14.
29. Limana F, Esposito G, D'Arcangelo D, et al. HMGB1 attenuates cardiac remodelling in the failing heart via enhanced cardiac regeneration and miR-206-mediated inhibition of TIMP-3. PLoS One 2011;6:e19845.
30. Bauer EM, Shapiro R, Zheng H, et al. High mobility group box 1 contributes to the pathogenesis of experimental pulmonary hypertension via activation of Toll-like receptor 4. Mol Med 2012;18: 1509-18.
31. Guo SW, Thompson EA. Performing the exact test of Hardy-Weinberg proportion for multiple alleles. Biometrics 1992;48: 361-72.
32. Zeng L, Zhang AQ, Gu W, et al. Clinical relevance of single nucleotide polymorphisms of the high mobility group box 1 protein gene in patients with major trauma in southwest China. Surgery 2012;151:427-36.
33. Kornblit B, Masmas T, Petersen SL, et al. Association of HMGB1 polymorphisms with outcome after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2010;16:239-52.
34. Lunetta KL, D'Agostino RB Sr, Karasik D, et al. Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. BMC Med Genet 2007; 8:S13.
35. Shen C, Lu X, Li Y, et al. Emilin1 gene and essential hypertension: a two-stage association study in northern Han Chinese population. BMC Med Genet 2009;10:118.
36. Lasky-Su J, Lyon HN, Emilsson V, et al. On the replication of genetic associations: timing can be everything! Am J Hum Genet 2008;82:849-58.
37. Percy CJ, Brown L, Power DA, et al. Obesity and hypertension have differing oxidant handling molecular pathways in age-related chronic kidney disease. Mech Ageing Dev 2009;130:129-38.
38. Darne B, Girerd X, Safar M, et al. Pulsatile versus steady component of blood pressure: a cross-sectional analysis and a prospective analysis on cardiovascular mortality. Hypertension 1989;13:392-400.
39. Bostom AG, Cupples LA, Jenner JL, et al. Elevated plasma lipoprotein(a) and coronary heart disease in men aged 55 years and younger. A prospective study. J Am Med Assoc 1996;276:544-8.
40. Kannel WB, Hjortland MC, McNamara PM, Gordon T. Menopause and risk of cardiovascular disease: the Framingham study. Ann Intern Med 1976;85:447-52.
41. Berry JD, Dyer A, Cai X, et al. Lifetime risks of cardiovascular disease. N Engl J Med 2012;366:321-9.
42. Yang S, Wang H, Yang Y, et al. Association study of AGER gene polymorphism and hypertension in Han Chinese population. Gene 2012;498:311-16.