Mitomycin C induces apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via a mitochondrial-mediated pathway

Cellular Physiology and Biochemistry

Volumn 35, Issue 3, 2015, Pages 1125-1136

  Yan, Chuqi ^a   Kong, Dechao ^b   Ge, Dong ^c   Zhang, Yanming ^d   Zhang, Xishan ^d   Su, Changhui ^d   Cao, Xiaojian ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b SHANGHAI FIRST PEOPLE S HOSPITAL   (China)

^c Central Hospital of Taian   (China)

^d SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Fibroblast like synoviocytes; Mitochondrial pathway; Mitomycin C; Rheumatoid arthritis

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; MITOMYCIN; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; MITOCHONDRIAL PROTEIN;

APOPTOSIS; ARTICLE; CELL VIABILITY; CYTOSOLIC FRACTION; DOSE RESPONSE; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL CULTURE; HUMAN TISSUE; INTRACELLULAR SIGNALING; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; ARTHRITIS, RHEUMATOID; BIOSYNTHESIS; CELL COUNT; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION; METABOLISM; MITOCHONDRION; PATHOLOGY; SIGNAL TRANSDUCTION; SYNOVIAL FLUID;

APOPTOSIS; ARTHRITIS, RHEUMATOID; CELL COUNT; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; FIBROBLASTS; GENE EXPRESSION; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MITOMYCIN; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SYNOVIAL FLUID;

EID: 84924700102     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000373938     Document Type: Article

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