-
1
-
-
36849021771
-
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
-
Higgins DF, Kimura K, Bernhardt, et al: Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest 117: 3810-3820, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 3810-3820
-
-
Higgins, D.F.1
Kimura, K.2
Bernhardt3
-
2
-
-
38549159026
-
Cellular and molecular mechanisms of fibrosis
-
Wynn TA: Cellular and molecular mechanisms of fibrosis. J Pathol 214: 199-210, 2008.
-
(2008)
J Pathol
, vol.214
, pp. 199-210
-
-
Wynn, T.A.1
-
3
-
-
33847350691
-
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
-
Wynn TA: Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J Clin Invest 117: 524-529, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 524-529
-
-
Wynn, T.A.1
-
4
-
-
79960421272
-
The genetics of systemic sclerosis: An update
-
Romano E, Manetti M, Guiducci S, Ceccarelli C, Allanore Y and Matucci-Cerinic M: The genetics of systemic sclerosis: an update. Clin Exp Rheumatol 29: S75-S86, 2011.
-
(2011)
Clin Exp Rheumatol
, vol.29
, pp. S75-S86
-
-
Romano, E.1
Manetti, M.2
Guiducci, S.3
Ceccarelli, C.4
Allanore, Y.5
Matucci-Cerinic, M.6
-
5
-
-
84892378680
-
Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant Fibrosis
-
Zell S, Schmitt R, Witting S, Kreipe HH, Hussein K and Becker JU: Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant Fibrosis. Nephron Extra 3: 50-58, 2013.
-
(2013)
Nephron Extra
, vol.3
, pp. 50-58
-
-
Zell, S.1
Schmitt, R.2
Witting, S.3
Kreipe, H.H.4
Hussein, K.5
Becker, J.U.6
-
6
-
-
82355190219
-
Cellular and molecular mechanisms of renal fibrosis
-
Liu Y: Cellular and molecular mechanisms of renal fibrosis. Nat Rev Nephrol 7: 684-696, 2011.
-
(2011)
Nat Rev Nephrol
, vol.7
, pp. 684-696
-
-
Liu, Y.1
-
7
-
-
84879380816
-
Norcantharidin inhibits renal interstitial fibrosis by blocking the tubular epithelial-mesenchymal transition
-
Li Y, Sun Y, Liu F, et al: Norcantharidin inhibits renal interstitial fibrosis by blocking the tubular epithelial-mesenchymal transition. PLoS One 8: e66356, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e66356
-
-
Li, Y.1
Sun, Y.2
Liu, F.3
-
8
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R and Neilson EG: Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 1776-1784, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
9
-
-
79551521517
-
Epithelial-mesenchymal transition (EMT) in kidney fibrosis: Fact or fantasy
-
Kriz W, Kaissling B and Le Hir M: Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy? J Clin Invest 121: 468-474, 2011.
-
(2011)
J Clin Invest
, vol.121
, pp. 468-474
-
-
Kriz, W.1
Kaissling, B.2
Le Hir, M.3
-
10
-
-
79551479332
-
Renal interstitial fibrosis: A critical evaluation of the origin of myofibroblasts
-
Barnes JL and Glass WF II: Renal interstitial fibrosis: a critical evaluation of the origin of myofibroblasts. Contrib Nephrol 169: 73-93, 2011.
-
(2011)
Contrib Nephrol
, vol.169
, pp. 73-93
-
-
Barnes, J.L.1
Glass, W.F.2
-
11
-
-
77949351029
-
New insights into epithelial-mesenchymal transition in kidney fibrosis
-
Liu Y: New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol 21: 212-222, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 212-222
-
-
Liu, Y.1
-
12
-
-
84860830113
-
Epithelial-mesenchymal transition: General principles and pathological relevance with special emphasis on the role of matrix metalloproteinases
-
Nisticò P, Bissell MJ and Radisky DC: Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases. Cold Spring Harb Perspect Biol 4: a011908, 2012.
-
(2012)
Cold Spring Harb Perspect Biol
, vol.4
, pp. a011908
-
-
Nisticò, P.1
Bissell, M.J.2
Radisky, D.C.3
-
13
-
-
84859413955
-
Role of TGF in chronic kidney disease: An integration of tubular, glomerular and vascular effects
-
López-Hernández FJ and López-Novoa JM: Role of TGF in chronic kidney disease: an integration of tubular, glomerular and vascular effects. Cell Tissue Res 347: 141-154, 2012.
-
(2012)
Cell Tissue Res
, vol.347
, pp. 141-154
-
-
López-Hernández, F.J.1
López-Novoa, J.M.2
-
14
-
-
0036277026
-
Myofibroblasts and mechano-regulation of connective tissue remodelling
-
Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C and Brown RA: Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 3: 349-363, 2002.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 349-363
-
-
Tomasek, J.J.1
Gabbiani, G.2
Hinz, B.3
Chaponnier, C.4
Brown, R.A.5
-
15
-
-
33847347313
-
ECM remodeling in hypertensive heart disease
-
Berk BC, Fujiwara K and Lehoux S: ECM remodeling in hypertensive heart disease. J Clin Invest 117: 568-575, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 568-575
-
-
Berk, B.C.1
Fujiwara, K.2
Lehoux, S.3
-
16
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB and Bartel DP: Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20, 2005.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
17
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP: MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233, 2009.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
18
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight
-
Filipowicz W, Bhattacharyya SN and Sonenberg N: Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9: 102-114, 2008.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
19
-
-
78751509272
-
What goes up must come down: The emerging role of microRNA in fibrosis
-
Chau BN and Brenner DA: What goes up must come down: the emerging role of microRNA in fibrosis. Hepatology 53: 4-6, 2011.
-
(2011)
Hepatology
, vol.53
, pp. 4-6
-
-
Chau, B.N.1
Brenner, D.A.2
-
21
-
-
77957729712
-
The origin of fibroblasts and mechanism of cardiac fibrosis
-
Krenning G, Zeisberg EM and Kalluri R: The origin of fibroblasts and mechanism of cardiac fibrosis. J Cell Physiol 225: 631-637, 2010.
-
(2010)
J Cell Physiol
, vol.225
, pp. 631-637
-
-
Krenning, G.1
Zeisberg, E.M.2
Kalluri, R.3
-
22
-
-
79960381007
-
Integrating mechanisms of pulmonary fibrosis
-
Wynn TA: Integrating mechanisms of pulmonary fibrosis. J Exp Med 208: 1339-1350, 2011.
-
(2011)
J Exp Med
, vol.208
, pp. 1339-1350
-
-
Wynn, T.A.1
-
23
-
-
78751516162
-
MiR-200a prevents renal fibrogenesis through repression of TGF2 expression
-
Wang B, Koh P, Winbanks C, et al: miR-200a prevents renal fibrogenesis through repression of TGF2 expression. Diabetes 60: 280-287, 2011.
-
(2011)
Diabetes
, vol.60
, pp. 280-287
-
-
Wang, B.1
Koh, P.2
Winbanks, C.3
-
24
-
-
80052316668
-
Smad3-mediated upregulation of miR-21 promotes renal fibrosis
-
Zhong X, Chung AC, Chen HY, Meng XM and Lan HY: Smad3-mediated upregulation of miR-21 promotes renal fibrosis. J Am Soc Nephrol 22: 1668-1681, 2011.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1668-1681
-
-
Zhong, X.1
Chung, A.C.2
Chen, H.Y.3
Meng, X.M.4
Lan, H.Y.5
-
25
-
-
33847682663
-
MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-induced collagen expression via inhibition of E-box repressors
-
Kato M, Zhang J, Wang M, et al: MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci USA 104: 3432-3437, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 3432-3437
-
-
Kato, M.1
Zhang, J.2
Wang, M.3
-
26
-
-
77958065302
-
The VHL-dependent regulation of microRNAs in renal cancer
-
Neal CS, Michael MZ, Rawlings LH, Van der Hoek MB and Gleadle JM: The VHL-dependent regulation of microRNAs in renal cancer. BMC Med 8: 64, 2010.
-
(2010)
BMC Med
, vol.8
, pp. 64
-
-
Neal, C.S.1
Michael, M.Z.2
Rawlings, L.H.3
Van Der Hoek, M.B.4
Gleadle, J.M.5
-
27
-
-
84872319199
-
Circulating levels of inflammation-associated miR-155 and endothelial-enriched miR-126 in patients with end-stage renal disease
-
Wang H, Peng W, Shen X, Huang Y, Ouyang X and Dai Y: Circulating levels of inflammation-associated miR-155 and endothelial-enriched miR-126 in patients with end-stage renal disease. Braz J Med Biol Res 45: 1308-1314, 2012.
-
(2012)
Braz J Med Biol Res
, vol.45
, pp. 1308-1314
-
-
Wang, H.1
Peng, W.2
Shen, X.3
Huang, Y.4
Ouyang, X.5
Dai, Y.6
-
28
-
-
65249122551
-
MicroRNA expression profiles predictive of human renal allograft status
-
Anglicheau D, Sharma VK, Ding R, et al: MicroRNA expression profiles predictive of human renal allograft status. Proc Natl Acad Sci USA 106: 5330-5335, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 5330-5335
-
-
Anglicheau, D.1
Sharma, V.K.2
Ding, R.3
-
29
-
-
69249202575
-
Identification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: Implication in epithelial-mesenchymal interactions
-
Pottier N, Maurin T, Chevalier B, et al: Identification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: implication in epithelial-mesenchymal interactions. PLoS One 4: e6718, 2009.
-
(2009)
PLoS One
, vol.4
, pp. e6718
-
-
Pottier, N.1
Maurin, T.2
Chevalier, B.3
-
30
-
-
78650658467
-
Inducible microRNA-155 feedback promotes type i IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1
-
Wang P, Hou J, Lin L, et al: Inducible microRNA-155 feedback promotes type I IFN signaling in antiviral innate immunity by targeting suppressor of cytokine signaling 1. J Immunol 185: 6226-6233, 2010.
-
(2010)
J Immunol
, vol.185
, pp. 6226-6233
-
-
Wang, P.1
Hou, J.2
Lin, L.3
-
31
-
-
84873111777
-
Renal oxygenation and haemodynamics in acute kidney injury and chronic kidney disease
-
Singh P, Ricksten SE, Bragadottir G, Redfors B and Nordquist L: Renal oxygenation and haemodynamics in acute kidney injury and chronic kidney disease. Clin Exp Pharmacol Physiol 40: 138-147, 2013.
-
(2013)
Clin Exp Pharmacol Physiol
, vol.40
, pp. 138-147
-
-
Singh, P.1
Ricksten, S.E.2
Bragadottir, G.3
Redfors, B.4
Nordquist, L.5
-
32
-
-
84875640758
-
Bone marrow progenitor cell therapy-mediated paracrine regulation of cardiac miRNA-155 modulates fibrotic response in diabetic hearts
-
Kishore R, Verma SK, Mackie AR, et al: Bone marrow progenitor cell therapy-mediated paracrine regulation of cardiac miRNA-155 modulates fibrotic response in diabetic hearts. PLoS One 8: e60161, 2013.
-
(2013)
PLoS One
, vol.8
, pp. e60161
-
-
Kishore, R.1
Verma, S.K.2
Mackie, A.R.3
-
33
-
-
0036359548
-
Hypoxia a key regulatory factor in tumour growth
-
Harris AL: Hypoxia a key regulatory factor in tumour growth. Nat Rev Cancer 2: 38-47, 2002.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
34
-
-
84856739946
-
Hypoxia-inducible factors in physiology and medicine
-
Semenza GL: Hypoxia-inducible factors in physiology and medicine. Cell 148: 399-408, 2012.
-
(2012)
Cell
, vol.148
, pp. 399-408
-
-
Semenza, G.L.1
-
35
-
-
84861845402
-
The updated biology of hypoxia-inducible factor
-
Greer SN, Metcalf JL, Wang Y and Ohh M: The updated biology of hypoxia-inducible factor. EMBO J 31: 2448-2460, 2012.
-
(2012)
EMBO J
, vol.31
, pp. 2448-2460
-
-
Greer, S.N.1
Metcalf, J.L.2
Wang, Y.3
Ohh, M.4
-
36
-
-
44349140101
-
Hypoxia-inducible factor signaling in the development of tissue fibrosis
-
Higgins DF, Kimura K, Iwano M and Haase VH: Hypoxia-inducible factor signaling in the development of tissue fibrosis. Cell Cycle 7: 1128-1132, 2008.
-
(2008)
Cell Cycle
, vol.7
, pp. 1128-1132
-
-
Higgins, D.F.1
Kimura, K.2
Iwano, M.3
Haase, V.H.4
-
37
-
-
80053597754
-
MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia
-
Bruning U, Cerone L, Neufeld Z, et al: MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia. Mol Cell Biol 31: 4087-4096, 2011.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 4087-4096
-
-
Bruning, U.1
Cerone, L.2
Neufeld, Z.3
-
38
-
-
84893745579
-
MiR-155 at the heart of oncogenic pathways
-
Czyzyk-Krzeska MF and Zhang X: MiR-155 at the heart of oncogenic pathways. Oncogene 33: 677-678, 2014.
-
(2014)
Oncogene
, vol.33
, pp. 677-678
-
-
Czyzyk-Krzeska, M.F.1
Zhang, X.2
-
39
-
-
80052317444
-
The role of TGF-beta and epithelial-to mesenchymal transition in diabetic nephropathy
-
Hills CE and Squires PE: The role of TGF-beta and epithelial-to mesenchymal transition in diabetic nephropathy. Cytokine Growth Factor Rev 22: 131-139, 2011.
-
(2011)
Cytokine Growth Factor Rev
, vol.22
, pp. 131-139
-
-
Hills, C.E.1
Squires, P.E.2
-
40
-
-
84864865828
-
EMT and interstitial lung disease: A mysterious relationship
-
Kage H and Borok Z: EMT and interstitial lung disease: a mysterious relationship. Curr Opin Pulm Med 18: 517-523, 2012.
-
(2012)
Curr Opin Pulm Med
, vol.18
, pp. 517-523
-
-
Kage, H.1
Borok, Z.2
|