Sclareol, a plant diterpene, exhibits potent antiproliferative effects via the induction of apoptosis and mitochondrial membrane potential loss in osteosarcoma cancer cells

Molecular Medicine Reports

Volumn 11, Issue 6, 2015, Pages 4273-4278

  Wang, Lin ^a   He, Hong Sheng ^a   Yu, Hua Long ^a   Zeng, Yun ^a   Han, Heng ^a   He, Ning ^a   Liu, Zhi Gang ^a   Wang, Zhi Yong ^a   Xu, Shou Jia ^a   Xiong, Min ^a  

^a HUBEI UNIVERSITY OF MEDICINE   (China)

Author keywords

Antiproliferative; Apoptosis; Cell cycle; Mitochondrial membrane potential; Sclareol

Indexed keywords

ACETIC ACID ETHYL ESTER; ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; BUTANOL; CHLOROFORM; EUPHORBIA MACULATA EXTRACT; LACTATE DEHYDROGENASE; THROMBOXANE B2; UNCLASSIFIED DRUG; WATER; ANTINEOPLASTIC AGENT; DITERPENE; SCLAREOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING TIME; BLOOD CLOTTING TIME; CONTROLLED STUDY; EUPHORBIA MACULATA; FRACTIONATION; MALE; NONHUMAN; PLATELET-RICH PLASMA CELL; PROTHROMBIN TIME; RAT; THROMBOCYTE AGGREGATION; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; OSTEOSARCOMA; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DITERPENES; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; L-LACTATE DEHYDROGENASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; OSTEOSARCOMA;

EID: 84924674683     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3325     Document Type: Article

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