Hemodynamic shear stress via ROS modulates PCSK9 expression in human vascular endothelial and smooth muscle cells and along the mouse aorta

Antioxidants and Redox Signaling

Volumn 22, Issue 9, 2015, Pages 760-771

  Ding, Zufeng ^a,b,c   Liu, Shijie ^a,e   Wang, Xianwei ^a   Deng, Xiaoyan ^b   Fan, Yubo ^b   Sun, Changqing ^c   Wang, Yannian ^c   Mehta, Jawahar L ^a,d  

^a CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^b BEIHANG UNIVERSITY   (China)

^c ZHENGZHOU UNIVERSITY   (China)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^e UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOCYNIN; DIPHENYLIODONIUM SALT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KEXIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ACETOPHENONE DERIVATIVE; ANTIOXIDANT; CATION; CYBB PROTEIN, MOUSE; LIPOPOLYSACCHARIDE A; MEMBRANE PROTEIN; NEUTROPHIL CYTOSOLIC FACTOR 1; OLR1 PROTEIN, MOUSE; PCSK9 PROTEIN, HUMAN; PCSK9 PROTEIN, MOUSE; SERINE PROTEINASE;

ANIMAL TISSUE; AORTA; AORTA BIFURCATION; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEAR STRESS; VASCULAR SMOOTH MUSCLE; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GENETICS; HEMODYNAMICS; INFLAMMATION; MECHANICAL STRESS; METABOLISM; SMOOTH MUSCLE CELL; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM;

MUS;

ACETOPHENONES; ANIMALS; ANTIOXIDANTS; AORTA; ENDOTHELIUM, VASCULAR; HEMODYNAMICS; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; NF-KAPPA B; ONIUM COMPOUNDS; PROPROTEIN CONVERTASES; REACTIVE OXYGEN SPECIES; SCAVENGER RECEPTORS, CLASS E; SERINE ENDOPEPTIDASES; STRESS, MECHANICAL; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84924666822     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2014.6054     Document Type: Article

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