Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

American Journal of Physiology - Cell Physiology

Volumn 307, Issue 4, 2014, Pages

  Song, Shanshan ^a,b   Yamamura, Aya ^c   Yamamura, Hisao ^d   Ayon, Ramon J ^a,b   Smith, Kimberly A ^a   Tang, Haiyang ^a,b   Makino, Ayako ^a,b   Yuan, Jason X J ^a,b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c KINJO GAKUIN UNIVERSITY   (Japan)

^d NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Mechanosensitive channel; Shear stress; TRPM7; TRPV4

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; BRADYKININ; CALCIUM; CATION CHANNEL; RUTHENIUM RED; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; VANILLOID RECEPTOR 4;

ARTERY MUSCLE; ARTICLE; CALCIUM CELL LEVEL; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LUNG VASOCONSTRICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; SARCOPLASMIC RETICULUM; SHEAR STRESS; SMOOTH MUSCLE FIBER; UPREGULATION; WESTERN BLOTTING;

MECHANOSENSITIVE CHANNEL; SHEAR STRESS; TRPM7; TRPV4;

ARTERIAL PRESSURE; CALCIUM SIGNALING; CASE-CONTROL STUDIES; CELLS, CULTURED; HUMANS; HYPERTENSION, PULMONARY; MAGNESIUM; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE TRANSPORT MODULATORS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PULMONARY ARTERY; REGIONAL BLOOD FLOW; RNA INTERFERENCE; STRESS, MECHANICAL; TRANSFECTION; TRPM CATION CHANNELS; TRPV CATION CHANNELS; VASOCONSTRICTION;

EID: 84907677305     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00115.2014     Document Type: Article

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