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Volumn 17, Issue 2, 2015, Pages 177-186

Diagnosis and management of testosterone deficiency

Author keywords

androgens; erectile dysfunction; hormones; hypogonadism; testosterone

Indexed keywords

GLUCOCORTICOID; OPIATE; SEROTONIN UPTAKE INHIBITOR; TESTOSTERONE;

EID: 84924649961     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.4103/1008-682X.143317     Document Type: Review
Times cited : (29)

References (150)
  • 1
    • 68149138117 scopus 로고    scopus 로고
    • The dark side of testosterone deficiency: III. Cardiovascular disease
    • Traish AM, Saad F, Feeley RJ, Guay A. The dark side of testosterone deficiency: III. Cardiovascular disease. J Androl 2009; 30: 477-94.
    • (2009) J Androl , vol.30 , pp. 477-494
    • Traish, A.M.1    Saad, F.2    Feeley, R.J.3    Guay, A.4
  • 2
    • 58149310816 scopus 로고    scopus 로고
    • The dark side of testosterone deficiency: II. Type 2 diabetes and insulin resistance
    • Traish AM, Saad F, Guay A. The dark side of testosterone deficiency: II. Type 2 diabetes and insulin resistance. J Androl 2009; 30: 23-32.
    • (2009) J Androl , vol.30 , pp. 23-32
    • Traish, A.M.1    Saad, F.2    Guay, A.3
  • 3
    • 47549107694 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: The European male aging study
    • Wu FC, Tajar A, Pye SR, Silman AJ, Finn JD, et al. Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European male aging study. J Clin Endocrinol Metab 2008; 93: 2737-45.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 2737-2745
    • Wu, F.C.1    Tajar, A.2    Pye, S.R.3    Silman, A.J.4    Finn, J.D.5
  • 4
    • 26444515048 scopus 로고    scopus 로고
    • The decline of androgen levels in elderly men and its clinical and therapeutic implications
    • Kaufman JM, Vermeulen A. The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocr Rev 2005; 26: 833-76.
    • (2005) Endocr Rev , vol.26 , pp. 833-876
    • Kaufman, J.M.1    Vermeulen, A.2
  • 5
    • 53749098934 scopus 로고    scopus 로고
    • Correlates of low testosterone and symptomatic androgen deficiency in a population-based sample
    • Hall SA, Esche GR, Araujo AB, Travison TG, Clark RV, et al. Correlates of low testosterone and symptomatic androgen deficiency in a population-based sample. J Clin Endocrinol Metab 2008; 93: 3870-7.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3870-3877
    • Hall, S.A.1    Esche, G.R.2    Araujo, A.B.3    Travison, T.G.4    Clark, R.V.5
  • 7
    • 10344243498 scopus 로고    scopus 로고
    • Prevalence and incidence of androgen deficiency in middle-aged and older men: Estimates from the Massachusetts Male Aging Study
    • Araujo AB, O'Donnell AB, Brambilla DJ, Simpson WB, Longcope C, et al. Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study. J Clin Endocrinol Metab 2004; 89: 5920-6.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 5920-5926
    • Araujo, A.B.1    O'Donnell, A.B.2    Brambilla, D.J.3    Simpson, W.B.4    Longcope, C.5
  • 8
    • 0028979570 scopus 로고
    • Ageing of the hypothalamo-pituitary-testicular axis in men
    • Vermeulen A, Kaufman JM. Ageing of the hypothalamo-pituitary-testicular axis in men. Horm Res 1995; 43: 25-8.
    • (1995) Horm Res , vol.43 , pp. 25-28
    • Vermeulen, A.1    Kaufman, J.M.2
  • 9
    • 84872236971 scopus 로고    scopus 로고
    • Androgen deficiency in older men: Indications, advantages, and pitfalls of testosterone replacement therapy
    • McGill JJ, Shoskes DA, Sabanegh ES. Androgen deficiency in older men: indications, advantages, and pitfalls of testosterone replacement therapy. Cleve Clin J Med 2012; 79: 797-806.
    • (2012) Cleve Clin J Med , vol.79 , pp. 797-806
    • McGill, J.J.1    Shoskes, D.A.2    Sabanegh, E.S.3
  • 10
    • 44349169518 scopus 로고    scopus 로고
    • Treatment of symptomatic androgen deficiency: Results from the Boston Area Community Health Survey
    • Hall SA, Araujo AB, Esche GR, Williams RE, Clark RV, et al. Treatment of symptomatic androgen deficiency: results from the Boston Area Community Health Survey. Arch Intern Med 2008; 168: 1070-6.
    • (2008) Arch Intern Med , vol.168 , pp. 1070-1076
    • Hall, S.A.1    Araujo, A.B.2    Esche, G.R.3    Williams, R.E.4    Clark, R.V.5
  • 11
    • 84889081877 scopus 로고    scopus 로고
    • Male reproductive physiology
    • Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters AP, editors Philadelphia: Elsevier-Saunders
    • Turek PJ. Male reproductive physiology. In: Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters AP, editors. Campbell-Walsh Urology. 10 th ed. Philadelphia: Elsevier-Saunders; 2012. p. 591-615.
    • (2012) Campbell-Walsh Urology. 10 th Ed. , pp. 591-615
    • Turek, P.J.1
  • 12
    • 54149084920 scopus 로고    scopus 로고
    • The impact of assay quality and reference ranges on clinical decision making in the diagnosis of androgen disorders
    • Bhasin S, Zhang A, Coviello A, Jasuja R, Ulloor J, et al. The impact of assay quality and reference ranges on clinical decision making in the diagnosis of androgen disorders. Steroids 2008; 73: 1311-7.
    • (2008) Steroids , vol.73 , pp. 1311-1317
    • Bhasin, S.1    Zhang, A.2    Coviello, A.3    Jasuja, R.4    Ulloor, J.5
  • 13
    • 33846991956 scopus 로고    scopus 로고
    • Position statement: Utility, limitations, and pitfalls in measuring testosterone: An Endocrine Society position statement
    • Rosner W, Auchus RJ, Azziz R, Sluss PM, Raff H. Position statement: utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement. J Clin Endocrinol Metab 2007; 92: 405-13.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 405-413
    • Rosner, W.1    Auchus, R.J.2    Azziz, R.3    Sluss, P.M.4    Raff, H.5
  • 14
    • 84892247412 scopus 로고    scopus 로고
    • Testes
    • Greenspan FS, Strewler GJ, editors Stamford Connecticut: Appleton and Lange
    • th ed. Stamford Connecticut: Appleton and Lange; 1997. p. 422-52.
    • (1997) th Ed. , pp. 422-452
    • Braunstein, G.D.1
  • 15
    • 0036858514 scopus 로고    scopus 로고
    • American Association of Clinical Endocrinologists Medical Guidelines for clinical practice for the evaluation and treatment of hypogonadism in adult male patients-2002 update
    • Petak SM, Nankin HR, Spark RF, Swerdloff RS, Rodriguez-Rigau JL, et al. American Association of Clinical Endocrinologists Medical Guidelines for clinical practice for the evaluation and treatment of hypogonadism in adult male patients-2002 update. Endocr Pract 2002; 8: 440-56.
    • (2002) Endocr Pract , vol.8 , pp. 440-456
    • Petak, S.M.1    Nankin, H.R.2    Spark, R.F.3    Swerdloff, R.S.4    Rodriguez-Rigau, J.L.5
  • 16
    • 0034937154 scopus 로고    scopus 로고
    • Assessment of the androgen environment within the human testis: Minimally invasive method to obtain intratesticular fluid
    • Jarow JP, Chen H, Rosner TW, Trentacoste S, Zirkin BR. Assessment of the androgen environment within the human testis: minimally invasive method to obtain intratesticular fluid. J Androl 2001; 22: 640-5.
    • (2001) J Androl , vol.22 , pp. 640-645
    • Jarow, J.P.1    Chen, H.2    Rosner, T.W.3    Trentacoste, S.4    Zirkin, B.R.5
  • 17
    • 84870266501 scopus 로고    scopus 로고
    • Male hypogonadism: More than just a low testosterone
    • Pantalone KM, Faiman C. Male hypogonadism: more than just a low testosterone. Cleve Clin J Med 2012; 79: 717-25.
    • (2012) Cleve Clin J Med , vol.79 , pp. 717-725
    • Pantalone, K.M.1    Faiman, C.2
  • 18
    • 0020635522 scopus 로고
    • Loss of circadian rhythmicity in blood testosterone levels with aging in normal men
    • Bremner WJ, Vitiello MV, Prinz PN. Loss of circadian rhythmicity in blood testosterone levels with aging in normal men. J Clin Endocrinol Metab 1983; 56: 1278-81.
    • (1983) J Clin Endocrinol Metab , vol.56 , pp. 1278-1281
    • Bremner, W.J.1    Vitiello, M.V.2    Prinz, P.N.3
  • 19
    • 36249031484 scopus 로고    scopus 로고
    • Intraindividual variation in levels of serum testosterone and other reproductive and adrenal hormones in men
    • Brambilla DJ, O'Donnell AB, Matsumoto AM, McKinlay JB. Intraindividual variation in levels of serum testosterone and other reproductive and adrenal hormones in men. Clin Endocrinol (Oxf) 2007; 67: 853-62.
    • (2007) Clin Endocrinol (Oxf) , vol.67 , pp. 853-862
    • Brambilla, D.J.1    O'Donnell, A.B.2    Matsumoto, A.M.3    McKinlay, J.B.4
  • 20
    • 34547632140 scopus 로고    scopus 로고
    • The association of time of day and serum testosterone concentration in a large screening population
    • Crawford ED, Barqawi AB, O'Donnell C, Morgentaler A. The association of time of day and serum testosterone concentration in a large screening population. BJU Int 2007; 100: 509-13.
    • (2007) BJU Int , vol.100 , pp. 509-513
    • Crawford, E.D.1    Barqawi, A.B.2    O'Donnell, C.3    Morgentaler, A.4
  • 21
    • 84875443438 scopus 로고    scopus 로고
    • The evidence for seasonal variations of testosterone in men
    • Smith RP, Coward RM, Kovac JR, Lipshultz LI. The evidence for seasonal variations of testosterone in men. Maturitas 2013; 74: 208-12.
    • (2013) Maturitas , vol.74 , pp. 208-212
    • Smith, R.P.1    Coward, R.M.2    Kovac, J.R.3    Lipshultz, L.I.4
  • 23
    • 77954409942 scopus 로고    scopus 로고
    • Testosterone therapy in men with androgen deficiency syndromes: An endocrine society clinical practice guideline
    • Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, et al. Testosterone therapy in men with androgen deficiency syndromes: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2010; 95: 2536-59.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 2536-2559
    • Bhasin, S.1    Cunningham, G.R.2    Hayes, F.J.3    Matsumoto, A.M.4    Snyder, P.J.5
  • 26
    • 75149172663 scopus 로고    scopus 로고
    • Hypogonadism in men with erectile dysfunction may be related to a host of chronic illnesses
    • Guay A, Seftel AD, Traish A. Hypogonadism in men with erectile dysfunction may be related to a host of chronic illnesses. Int J Impot Res 2010; 22: 9-19.
    • (2010) Int J Impot Res , vol.22 , pp. 9-19
    • Guay, A.1    Seftel, A.D.2    Traish, A.3
  • 27
    • 0037326103 scopus 로고    scopus 로고
    • Prenatal and postnatal prevalence of Klinefelter syndrome: A national registry study
    • Bojesen A, Juul S, Gravholt CH. Prenatal and postnatal prevalence of Klinefelter syndrome: a national registry study. J Clin Endocrinol Metab 2003; 88: 622-6.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 622-626
    • Bojesen, A.1    Juul, S.2    Gravholt, C.H.3
  • 28
    • 79960800395 scopus 로고    scopus 로고
    • Varicocele as a risk factor for androgen deficiency and effect of repair
    • Tanrikut C, Goldstein M, Rosoff JS, Lee RK, Nelson CJ, et al. Varicocele as a risk factor for androgen deficiency and effect of repair. BJU Int 2011; 108: 1480-4.
    • (2011) BJU Int , vol.108 , pp. 1480-1484
    • Tanrikut, C.1    Goldstein, M.2    Rosoff, J.S.3    Lee, R.K.4    Nelson, C.J.5
  • 29
    • 84892313974 scopus 로고    scopus 로고
    • Disorders at the testicular level
    • Nieschlag E, Behre HM, Nieschlag S, editors Berlin: Springer
    • rd ed. Berlin: Springer; 2010. p. 193-238.
    • (2010) rd Ed. , pp. 193-238
    • Nieschlag, E.1    Behre, H.M.2    Wieacker, P.3
  • 30
    • 56249088599 scopus 로고    scopus 로고
    • Investigation, treatment, and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA, and ASA recommendations
    • Wang C, Nieschlag E, Swerdloff R, Behre HM, Hellstrom WJ, et al. Investigation, treatment, and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA, and ASA recommendations. Eur Urol 2009; 55: 121-30.
    • (2009) Eur Urol , vol.55 , pp. 121-130
    • Wang, C.1    Nieschlag, E.2    Swerdloff, R.3    Behre, H.M.4    Hellstrom, W.J.5
  • 31
    • 0036613016 scopus 로고    scopus 로고
    • International Society for the Study of the Aging Male. Investigation, treatment and monitoring of late-onset hypogonadism in males. Official recommendations of ISSAM. International Society for the Study of the Aging Male
    • Morales A, Lunenfeld B, International Society for the Study of the Aging Male. Investigation, treatment and monitoring of late-onset hypogonadism in males. Official recommendations of ISSAM. International Society for the Study of the Aging Male. Aging Male 2002; 5: 74-86.
    • (2002) Aging Male , vol.5 , pp. 74-86
    • Morales, A.1    Lunenfeld, B.2
  • 32
    • 77951642063 scopus 로고    scopus 로고
    • Characteristics of secondary, primary, and compensated hypogonadism in aging men: Evidence from the European Male Ageing Study
    • Tajar A, Forti G, O'Neill TW, Lee DM, Silman AJ, et al. Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study. J Clin Endocrinol Metab 2010; 95: 1810-8.
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 1810-1818
    • Tajar, A.1    Forti, G.2    O'Neill, T.W.3    Lee, D.M.4    Silman, A.J.5
  • 33
    • 0025101215 scopus 로고
    • Glucocorticoid-induced osteoporosis: Pathogenesis and management
    • Lukert BP, Raisz LG. Glucocorticoid-induced osteoporosis: pathogenesis and management. Ann Intern Med 1990; 112: 352-64.
    • (1990) Ann Intern Med , vol.112 , pp. 352-364
    • Lukert, B.P.1    Raisz, L.G.2
  • 35
    • 0027948610 scopus 로고
    • Testosterone levels during systemic and inhaled corticosteroid therapy
    • Morrison D, Capewell S, Reynolds SP, Thomas J, Ali NJ, et al. Testosterone levels during systemic and inhaled corticosteroid therapy. Respir Med 1994; 88: 659-63.
    • (1994) Respir Med , vol.88 , pp. 659-663
    • Morrison, D.1    Capewell, S.2    Reynolds, S.P.3    Thomas, J.4    Ali, N.J.5
  • 36
    • 0017260590 scopus 로고
    • Glucocorticoid therapy
    • Axelrod L. Glucocorticoid therapy. Medicine (Baltimore) 1976; 55: 39-65.
    • (1976) Medicine (Baltimore) , vol.55 , pp. 39-65
    • Axelrod, L.1
  • 37
    • 0017594992 scopus 로고
    • Effects of an anabolic steroid (metandienone) on spermatogenesis
    • Holma PK. Effects of an anabolic steroid (metandienone) on spermatogenesis. Contraception 1977; 15: 151-62.
    • (1977) Contraception , vol.15 , pp. 151-162
    • Holma, P.K.1
  • 38
    • 33646153302 scopus 로고    scopus 로고
    • Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: An integrated analysis
    • Liu PY, Swerdloff RS, Christenson PD, Handelsman DJ, Wang C, et al. Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis. Lancet 2006; 367: 1412-20.
    • (2006) Lancet , vol.367 , pp. 1412-1420
    • Liu, P.Y.1    Swerdloff, R.S.2    Christenson, P.D.3    Handelsman, D.J.4    Wang, C.5
  • 39
    • 0025302780 scopus 로고
    • Anabolic steroid-induced hypogonadotropic hypogonadism
    • Jarow JP, Lipshultz LI. Anabolic steroid-induced hypogonadotropic hypogonadism. Am J Sports Med 1990; 18: 429-31.
    • (1990) Am J Sports Med , vol.18 , pp. 429-431
    • Jarow, J.P.1    Lipshultz, L.I.2
  • 41
    • 84865327146 scopus 로고    scopus 로고
    • Testosterone recovery in the off-treatment time in prostate cancer patients undergoing intermittent androgen deprivation therapy
    • Tunn UW, Canepa G, Kochanowsky A, Kienle E. Testosterone recovery in the off-treatment time in prostate cancer patients undergoing intermittent androgen deprivation therapy. Prostate Cancer Prostatic Dis 2012; 15: 296-302.
    • (2012) Prostate Cancer Prostatic Dis , vol.15 , pp. 296-302
    • Tunn, U.W.1    Canepa, G.2    Kochanowsky, A.3    Kienle, E.4
  • 42
    • 34548806500 scopus 로고    scopus 로고
    • Association between megestrol acetate treatment and symptomatic adrenal insufficiency with hypogonadism in male patients with cancer
    • Dev R, Del Fabbro E, Bruera E. Association between megestrol acetate treatment and symptomatic adrenal insufficiency with hypogonadism in male patients with cancer. Cancer 2007; 110: 1173-7.
    • (2007) Cancer , vol.110 , pp. 1173-1177
    • Dev, R.1    Del Fabbro, E.2    Bruera, E.3
  • 43
    • 33644657895 scopus 로고    scopus 로고
    • Open-label pilot study of testosterone patch therapy in men with opioid-induced androgen deficiency
    • Daniell HW, Lentz R, Mazer NA. Open-label pilot study of testosterone patch therapy in men with opioid-induced androgen deficiency. J Pain 2006; 7: 200-10.
    • (2006) J Pain , vol.7 , pp. 200-210
    • Daniell, H.W.1    Lentz, R.2    Mazer, N.A.3
  • 45
    • 67049116471 scopus 로고    scopus 로고
    • The impact of opioids on the endocrine system
    • Katz N, Mazer NA. The impact of opioids on the endocrine system. Clin J Pain 2009; 25: 170-5.
    • (2009) Clin J Pain , vol.25 , pp. 170-175
    • Katz, N.1    Mazer, N.A.2
  • 48
    • 0036796181 scopus 로고    scopus 로고
    • Hypogonadism in men consuming sustained-action oral opioids
    • Daniell HW. Hypogonadism in men consuming sustained-action oral opioids. J Pain 2002; 3: 377-84.
    • (2002) J Pain , vol.3 , pp. 377-384
    • Daniell, H.W.1
  • 51
    • 84874372959 scopus 로고    scopus 로고
    • The effect of statins on testosterone in men and women, a systematic review and meta-analysis of randomized controlled trials
    • Schooling CM, Au Yeung SL, Freeman G, Cowling BJ. The effect of statins on testosterone in men and women, a systematic review and meta-analysis of randomized controlled trials. BMC Med 2013; 11: 57.
    • (2013) BMC Med , vol.11 , pp. 57
    • Schooling, C.M.1    Au Yeung, S.L.2    Freeman, G.3    Cowling, B.J.4
  • 53
    • 0027210856 scopus 로고
    • Attenuated luteinizing hormone (LH) pulse amplitude but normal LH pulse frequency, and its relation to plasma androgens in hypogonadism of obese men
    • Vermeulen A, Kaufman JM, Deslypere JP, Thomas G. Attenuated luteinizing hormone (LH) pulse amplitude but normal LH pulse frequency, and its relation to plasma androgens in hypogonadism of obese men. J Clin Endocrinol Metab 1993; 76: 1140-6.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 1140-1146
    • Vermeulen, A.1    Kaufman, J.M.2    Deslypere, J.P.3    Thomas, G.4
  • 54
    • 0033304558 scopus 로고    scopus 로고
    • Leptin and androgens in male obesity: Evidence for leptin contribution to reduced androgen levels
    • Isidori AM, Caprio M, Strollo F, Moretti C, Frajese G, et al. Leptin and androgens in male obesity: evidence for leptin contribution to reduced androgen levels. J Clin Endocrinol Metab 1999; 84: 3673-80.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3673-3680
    • Isidori, A.M.1    Caprio, M.2    Strollo, F.3    Moretti, C.4    Frajese, G.5
  • 56
  • 57
    • 0242383371 scopus 로고    scopus 로고
    • Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnoea
    • Meston N, Davies RJ, Mullins R, Jenkinson C, Wass JA, et al. Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnoea. J Intern Med 2003; 254: 447-54.
    • (2003) J Intern Med , vol.254 , pp. 447-454
    • Meston, N.1    Davies, R.J.2    Mullins, R.3    Jenkinson, C.4    Wass, J.A.5
  • 59
    • 33644828241 scopus 로고    scopus 로고
    • Low sex hormone-binding globulin, total testosterone, and symptomatic androgen deficiency are associated with development of the metabolic syndrome in nonobese men
    • Kupelian V, Page ST, Araujo AB, Travison TG, Bremner WJ, et al. Low sex hormone-binding globulin, total testosterone, and symptomatic androgen deficiency are associated with development of the metabolic syndrome in nonobese men. J Clin Endocrinol Metab 2006; 91: 843-50.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 843-850
    • Kupelian, V.1    Page, S.T.2    Araujo, A.B.3    Travison, T.G.4    Bremner, W.J.5
  • 60
    • 38549132322 scopus 로고    scopus 로고
    • Metabolic syndrome and reproduction: I. Testicular function
    • Goulis DG, Tarlatzis BC. Metabolic syndrome and reproduction: I. testicular function. Gynecol Endocrinol 2008; 24: 33-9.
    • (2008) Gynecol Endocrinol , vol.24 , pp. 33-39
    • Goulis, D.G.1    Tarlatzis, B.C.2
  • 61
    • 79957491763 scopus 로고    scopus 로고
    • Testosterone deficiency and risk factors in the metabolic syndrome: Implications for erectile dysfunction
    • Guay AT, Traish A. Testosterone deficiency and risk factors in the metabolic syndrome: implications for erectile dysfunction. Urol Clin North Am 2011; 38: 175-83.
    • (2011) Urol Clin North Am , vol.38 , pp. 175-183
    • Guay, A.T.1    Traish, A.2
  • 64
    • 27344445189 scopus 로고    scopus 로고
    • A review of hypogonadism and erectile dysfunction among HIV-infected men during the pre- and post-HAART eras: Diagnosis, pathogenesis, and management
    • Crum NF, Furtek KJ, Olson PE, Amling CL, Wallace MR. A review of hypogonadism and erectile dysfunction among HIV-infected men during the pre- and post-HAART eras: diagnosis, pathogenesis, and management. AIDS Patient Care STDS 2005; 19: 655-71.
    • (2005) AIDS Patient Care STDS , vol.19 , pp. 655-671
    • Crum, N.F.1    Furtek, K.J.2    Olson, P.E.3    Amling, C.L.4    Wallace, M.R.5
  • 65
    • 0034456965 scopus 로고    scopus 로고
    • Prevalence of hypogonadism among men with weight loss related to human immunodeficiency virus infection who were receiving highly active antiretroviral therapy
    • Rietschel P, Corcoran C, Stanley T, Basgoz N, Klibanski A, et al. Prevalence of hypogonadism among men with weight loss related to human immunodeficiency virus infection who were receiving highly active antiretroviral therapy. Clin Infect Dis 2000; 31: 1240-4.
    • (2000) Clin Infect Dis , vol.31 , pp. 1240-1244
    • Rietschel, P.1    Corcoran, C.2    Stanley, T.3    Basgoz, N.4    Klibanski, A.5
  • 66
    • 10344231952 scopus 로고    scopus 로고
    • Loss of lean body and muscle mass correlates with androgen levels in hypogonadal men with acquired immunodeficiency syndrome and wasting
    • Grinspoon S, Corcoran C, Lee K, Burrows B, Hubbard J, et al. Loss of lean body and muscle mass correlates with androgen levels in hypogonadal men with acquired immunodeficiency syndrome and wasting. J Clin Endocrinol Metab 1996; 81: 4051-8.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4051-4058
    • Grinspoon, S.1    Corcoran, C.2    Lee, K.3    Burrows, B.4    Hubbard, J.5
  • 68
    • 7144257865 scopus 로고    scopus 로고
    • Effects of androgen administration in men with the AIDS wasting syndrome. A randomized, double-blind, placebo-controlled trial
    • Grinspoon S, Corcoran C, Askari H, Schoenfeld D, Wolf L, et al. Effects of androgen administration in men with the AIDS wasting syndrome. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 1998; 129: 18-26.
    • (1998) Ann Intern Med , vol.129 , pp. 18-26
    • Grinspoon, S.1    Corcoran, C.2    Askari, H.3    Schoenfeld, D.4    Wolf, L.5
  • 69
  • 71
    • 84856888490 scopus 로고    scopus 로고
    • The effect of testosterone supplementation on depression symptoms in hypogonadal men from the Testim Registry in the US (TRiUS)
    • Khera M, Bhattacharya RK, Blick G, Kushner H, Nguyen D, et al. The effect of testosterone supplementation on depression symptoms in hypogonadal men from the Testim Registry in the US (TRiUS). Aging Male 2012; 15: 14-21.
    • (2012) Aging Male , vol.15 , pp. 14-21
    • Khera, M.1    Bhattacharya, R.K.2    Blick, G.3    Kushner, H.4    Nguyen, D.5
  • 72
    • 33645962531 scopus 로고    scopus 로고
    • Are androgens critical for penile erections in humans? Examining the clinical and preclinical evidence
    • Traish AM, Guay AT. Are androgens critical for penile erections in humans? Examining the clinical and preclinical evidence. J Sex Med 2006; 3: 382-404.
    • (2006) J Sex Med , vol.3 , pp. 382-404
    • Traish, A.M.1    Guay, A.T.2
  • 73
    • 0032981996 scopus 로고    scopus 로고
    • Effects of castration and androgen replacement on erectile function in a rabbit model
    • Traish AM, Park K, Dhir V, Kim NN, Moreland RB, et al. Effects of castration and androgen replacement on erectile function in a rabbit model. Endocrinology 1999; 140: 1861-8.
    • (1999) Endocrinology , vol.140 , pp. 1861-1868
    • Traish, A.M.1    Park, K.2    Dhir, V.3    Kim, N.N.4    Moreland, R.B.5
  • 74
    • 80355142018 scopus 로고    scopus 로고
    • Does testosterone deficiency exaggerate the clinical symptoms of Peyronie's disease?
    • Nam HJ, Park HJ, Park NC. Does testosterone deficiency exaggerate the clinical symptoms of Peyronie's disease? Int J Urol 2011; 18: 796-800.
    • (2011) Int J Urol , vol.18 , pp. 796-800
    • Nam, H.J.1    Park, H.J.2    Park, N.C.3
  • 75
    • 84862525047 scopus 로고    scopus 로고
    • Association between Peyronie disease and low serum testosterone levels: Detection and therapeutic considerations
    • Cavallini G, Biagiotti G, Lo Giudice C. Association between Peyronie disease and low serum testosterone levels: detection and therapeutic considerations. J Androl 2012; 33: 381-8.
    • (2012) J Androl , vol.33 , pp. 381-388
    • Cavallini, G.1    Biagiotti, G.2    Lo Giudice, C.3
  • 76
    • 84924707740 scopus 로고    scopus 로고
    • Testosterone deficiency is similarly prevalent among men presenting with either peyronie's disease or erectile dysfunction
    • Coward RM, Verges D, Smith AB, Carson CC. Testosterone deficiency is similarly prevalent among men presenting with either peyronie's disease or erectile dysfunction. J Sex Med 2012; 9: 3-62.
    • (2012) J Sex Med , vol.9 , pp. 3-62
    • Coward, R.M.1    Verges, D.2    Smith, A.B.3    Carson, C.C.4
  • 77
    • 84903795358 scopus 로고    scopus 로고
    • Commentary: Who is a candidate for testosterone therapy? A synthesis of international expert opinions
    • Morgentaler A, Khera M, Maggi M, Zitzmann M. Commentary: who is a candidate for testosterone therapy? A synthesis of international expert opinions. J Sex Med 2014; 11: 1636-45.
    • (2014) J Sex Med , vol.11 , pp. 1636-1645
    • Morgentaler, A.1    Khera, M.2    Maggi, M.3    Zitzmann, M.4
  • 79
    • 33751533215 scopus 로고    scopus 로고
    • Association of specific symptoms and metabolic risks with serum testosterone in older men
    • Zitzmann M, Faber S, Nieschlag E. Association of specific symptoms and metabolic risks with serum testosterone in older men. J Clin Endocrinol Metab 2006; 91: 4335-43.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4335-4343
    • Zitzmann, M.1    Faber, S.2    Nieschlag, E.3
  • 80
    • 84902074891 scopus 로고    scopus 로고
    • Testosterone supplementation and sexual function: A meta-analysis study
    • Corona G, Isidori AM, Buvat J, Aversa A, Rastrelli G, et al. Testosterone supplementation and sexual function: a meta-analysis study. J Sex Med 2014; 11: 1577-92.
    • (2014) J Sex Med , vol.11 , pp. 1577-1592
    • Corona, G.1    Isidori, A.M.2    Buvat, J.3    Aversa, A.4    Rastrelli, G.5
  • 82
    • 69949087994 scopus 로고    scopus 로고
    • The age-related decline of testosterone is associated with different specific symptoms and signs in patients with sexual dysfunction
    • Corona G, Mannucci E, Ricca V, Lotti F, Boddi V, et al. The age-related decline of testosterone is associated with different specific symptoms and signs in patients with sexual dysfunction. Int J Androl 2009; 32: 720-8.
    • (2009) Int J Androl , vol.32 , pp. 720-728
    • Corona, G.1    Mannucci, E.2    Ricca, V.3    Lotti, F.4    Boddi, V.5
  • 83
    • 0037793319 scopus 로고    scopus 로고
    • Diurnal rhythms of serum total, free and bioavailable testosterone and of SHBG in middle-aged men compared with those in young men
    • Diver MJ, Imtiaz KE, Ahmad AM, Vora JP, Fraser WD. Diurnal rhythms of serum total, free and bioavailable testosterone and of SHBG in middle-aged men compared with those in young men. Clin Endocrinol (Oxf) 2003; 58: 710-7.
    • (2003) Clin Endocrinol (Oxf) , vol.58 , pp. 710-717
    • Diver, M.J.1    Imtiaz, K.E.2    Ahmad, A.M.3    Vora, J.P.4    Fraser, W.D.5
  • 85
    • 33744948333 scopus 로고    scopus 로고
    • Testosterone therapy in adult men with androgen deficiency syndromes: An endocrine society clinical practice guideline
    • Bhasin S, Cunningam GR, Hayes FJ, Matsumoto AM, Snyder PJ, et al. Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2006; 91: 1995-2010.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1995-2010
    • Bhasin, S.1    Cunningam, G.R.2    Hayes, F.J.3    Matsumoto, A.M.4    Snyder, P.J.5
  • 86
    • 35349019230 scopus 로고    scopus 로고
    • Androgen receptor gene CAG repeat length and body mass index modulate the safety of long-term intramuscular testosterone undecanoate therapy in hypogonadal men
    • Zitzmann M, Nieschlag E. Androgen receptor gene CAG repeat length and body mass index modulate the safety of long-term intramuscular testosterone undecanoate therapy in hypogonadal men. J Clin Endocrinol Metab 2007; 92: 3844-53.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3844-3853
    • Zitzmann, M.1    Nieschlag, E.2
  • 87
    • 59849123606 scopus 로고    scopus 로고
    • The role of the CAG repeat androgen receptor polymorphism in andrology
    • Zitzmann M. The role of the CAG repeat androgen receptor polymorphism in andrology. Front Horm Res 2009; 37: 52-61.
    • (2009) Front Horm Res , vol.37 , pp. 52-61
    • Zitzmann, M.1
  • 88
    • 40449116660 scopus 로고    scopus 로고
    • Free testosterone measurement by the analog displacement direct assay: Old concerns and new evidence
    • Swerdloff RS, Wang C. Free testosterone measurement by the analog displacement direct assay: old concerns and new evidence. Clin Chem 2008; 54: 458-60.
    • (2008) Clin Chem , vol.54 , pp. 458-460
    • Swerdloff, R.S.1    Wang, C.2
  • 89
    • 0033305020 scopus 로고    scopus 로고
    • A critical evaluation of simple methods for the estimation of free testosterone in serum
    • Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 1999; 84: 3666-72.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3666-3672
    • Vermeulen, A.1    Verdonck, L.2    Kaufman, J.M.3
  • 90
    • 34548324658 scopus 로고    scopus 로고
    • Effect of hyperprolactinemia in male patients consulting for sexual dysfunction
    • Corona G, Mannucci E, Fisher AD, Lotti F, Ricca V, et al. Effect of hyperprolactinemia in male patients consulting for sexual dysfunction. J Sex Med 2007; 4: 1485-93.
    • (2007) J Sex Med , vol.4 , pp. 1485-1493
    • Corona, G.1    Mannucci, E.2    Fisher, A.D.3    Lotti, F.4    Ricca, V.5
  • 91
    • 0030044727 scopus 로고    scopus 로고
    • Prevalence of hypothalamic-pituitary imaging abnormalities in impotent men with secondary hypogonadism
    • Citron JT, Ettinger B, Rubinoff H, Ettinger VM, Minkoff J, et al. Prevalence of hypothalamic-pituitary imaging abnormalities in impotent men with secondary hypogonadism. J Urol 1996; 155: 529-33.
    • (1996) J Urol , vol.155 , pp. 529-533
    • Citron, J.T.1    Ettinger, B.2    Rubinoff, H.3    Ettinger, V.M.4    Minkoff, J.5
  • 92
    • 33646060757 scopus 로고    scopus 로고
    • Klinefelter's syndrome - A microcosm of male reproductive health
    • Handelsman DJ, Liu PY. Klinefelter's syndrome - a microcosm of male reproductive health. J Clin Endocrinol Metab 2006; 91: 1220-2.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1220-1222
    • Handelsman, D.J.1    Liu, P.Y.2
  • 94
    • 0033304542 scopus 로고    scopus 로고
    • Effect of testosterone treatment on bone mineral density in men over 65 years of age
    • Snyder PJ, Peachey H, Hannoush P, Berlin JA, Loh L, et al. Effect of testosterone treatment on bone mineral density in men over 65 years of age. J Clin Endocrinol Metab 1999; 84: 1966-72.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1966-1972
    • Snyder, P.J.1    Peachey, H.2    Hannoush, P.3    Berlin, J.A.4    Loh, L.5
  • 95
    • 84898464356 scopus 로고    scopus 로고
    • Bone mineral density and response to treatment in men younger than 50 years with testosterone deficiency and sexual dysfunction or infertility
    • Kacker R, Conners W, Zade J, Morgentaler A. Bone mineral density and response to treatment in men younger than 50 years with testosterone deficiency and sexual dysfunction or infertility. J Urol 2014; 191: 1072-6.
    • (2014) J Urol , vol.191 , pp. 1072-1076
    • Kacker, R.1    Conners, W.2    Zade, J.3    Morgentaler, A.4
  • 97
    • 77949426910 scopus 로고    scopus 로고
    • The benefits and risks of testosterone replacement therapy: A review
    • Bassil N, Alkaade S, Morley JE. The benefits and risks of testosterone replacement therapy: a review. Ther Clin Risk Manag 2009; 5: 427-48.
    • (2009) Ther Clin Risk Manag , vol.5 , pp. 427-448
    • Bassil, N.1    Alkaade, S.2    Morley, J.E.3
  • 99
    • 45849101739 scopus 로고    scopus 로고
    • Invasive breast cancer after initiation of testosterone replacement therapy in a man - A warning to endocrinologists
    • Thomas SR, Evans PJ, Holland PA, Biswas M. Invasive breast cancer after initiation of testosterone replacement therapy in a man - a warning to endocrinologists. Endocr Pract 2008; 14: 201-3.
    • (2008) Endocr Pract , vol.14 , pp. 201-203
    • Thomas, S.R.1    Evans, P.J.2    Holland, P.A.3    Biswas, M.4
  • 101
    • 0019478982 scopus 로고
    • The response of metastatic adenocarcinoma of the prostate to exogenous testosterone
    • Fowler JE Jr, Whitmore WF Jr. The response of metastatic adenocarcinoma of the prostate to exogenous testosterone. J Urol 1981; 126: 372-5.
    • (1981) J Urol , vol.126 , pp. 372-375
    • Fowler, J.E.1    Whitmore, W.F.2
  • 103
    • 33646459214 scopus 로고    scopus 로고
    • Assessing prostate cancer risk: Results from the Prostate Cancer Prevention Trial
    • Thompson IM, Ankerst DP, Chi C, Goodman PJ, Tangen CM, et al. Assessing prostate cancer risk: results from the Prostate Cancer Prevention Trial. J Natl Cancer Inst 2006; 98: 529-34.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 529-534
    • Thompson, I.M.1    Ankerst, D.P.2    Chi, C.3    Goodman, P.J.4    Tangen, C.M.5
  • 104
    • 57649176913 scopus 로고    scopus 로고
    • Shifting the paradigm of testosterone and prostate cancer: The saturation model and the limits of androgen-dependent growth
    • Morgentaler A, Traish AM. Shifting the paradigm of testosterone and prostate cancer: the saturation model and the limits of androgen-dependent growth. Eur Urol 2009; 55: 310-20.
    • (2009) Eur Urol , vol.55 , pp. 310-320
    • Morgentaler, A.1    Traish, A.M.2
  • 105
    • 84888840943 scopus 로고    scopus 로고
    • A new era of testosterone and prostate cancer: From physiology to clinical implications
    • Khera M, Crawford D, Morales A, Salonia A, Morgentaler A. A new era of testosterone and prostate cancer: from physiology to clinical implications. Eur Urol 2014; 65: 115-23.
    • (2014) Eur Urol , vol.65 , pp. 115-123
    • Khera, M.1    Crawford, D.2    Morales, A.3    Salonia, A.4    Morgentaler, A.5
  • 106
    • 39149084101 scopus 로고    scopus 로고
    • Endogenous sex hormones and prostate cancer: A collaborative analysis of 18 prospective studies
    • Endogenous Hormones and Prostate Cancer Collaborative Group, Roddam AW, Allen NE, Appleby P, Key TJ. Endogenous sex hormones and prostate cancer: a collaborative analysis of 18 prospective studies. J Natl Cancer Inst 2008; 100: 170-83.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 170-183
    • Roddam, A.W.1    Allen, N.E.2    Appleby, P.3    Key, T.J.4
  • 107
    • 84867052045 scopus 로고    scopus 로고
    • Serum testosterone and dihydrotestosterone and prostate cancer risk in the placebo arm of the Reduction by Dutasteride of Prostate Cancer Events trial
    • Muller RL, Gerber L, Moreira DM, Andriole G, Castro-Santamaria R, et al. Serum testosterone and dihydrotestosterone and prostate cancer risk in the placebo arm of the Reduction by Dutasteride of Prostate Cancer Events trial. Eur Urol 2012; 62: 757-64.
    • (2012) Eur Urol , vol.62 , pp. 757-764
    • Muller, R.L.1    Gerber, L.2    Moreira, D.M.3    Andriole, G.4    Castro-Santamaria, R.5
  • 108
    • 58149512149 scopus 로고    scopus 로고
    • Testosterone therapy in hypogonadal men and potential prostate cancer risk: A systematic review
    • Shabsigh R, Crawford ED, Nehra A, Slawin KM. Testosterone therapy in hypogonadal men and potential prostate cancer risk: a systematic review. Int J Impot Res 2009; 21: 9-23.
    • (2009) Int J Impot Res , vol.21 , pp. 9-23
    • Shabsigh, R.1    Crawford, E.D.2    Nehra, A.3    Slawin, K.M.4
  • 109
    • 12544256922 scopus 로고    scopus 로고
    • Testosterone replacement therapy after primary treatment for prostate cancer
    • Agarwal PK, Oefelein MG. Testosterone replacement therapy after primary treatment for prostate cancer. J Urol 2005; 173: 533-6.
    • (2005) J Urol , vol.173 , pp. 533-536
    • Agarwal, P.K.1    Oefelein, M.G.2
  • 110
    • 4143066958 scopus 로고    scopus 로고
    • Androgen replacement after curative radical prostatectomy for prostate cancer in hypogonadal men
    • Kaufman JM, Graydon RJ. Androgen replacement after curative radical prostatectomy for prostate cancer in hypogonadal men. J Urol 2004; 172: 920-2.
    • (2004) J Urol , vol.172 , pp. 920-922
    • Kaufman, J.M.1    Graydon, R.J.2
  • 111
    • 63849109998 scopus 로고    scopus 로고
    • Testosterone replacement therapy following radical prostatectomy
    • Khera M, Grober ED, Najari B, Colen JS, Mohamed O, et al. Testosterone replacement therapy following radical prostatectomy. J Sex Med 2009; 6: 1165-70.
    • (2009) J Sex Med , vol.6 , pp. 1165-1170
    • Khera, M.1    Grober, E.D.2    Najari, B.3    Colen, J.S.4    Mohamed, O.5
  • 112
    • 57649148622 scopus 로고    scopus 로고
    • Testosterone administration to men with testosterone deficiency syndrome after external beam radiotherapy for localized prostate cancer: Preliminary observations
    • Morales A, Black AM, Emerson LE. Testosterone administration to men with testosterone deficiency syndrome after external beam radiotherapy for localized prostate cancer: preliminary observations. BJU Int 2009; 103: 62-4.
    • (2009) BJU Int , vol.103 , pp. 62-64
    • Morales, A.1    Black, A.M.2    Emerson, L.E.3
  • 113
    • 84880036090 scopus 로고    scopus 로고
    • Testosterone replacement therapy in patients with prostate cancer after radical prostatectomy
    • Pastuszak AW, Pearlman AM, Lai WS, Godoy G, Sathyamoorthy K, et al. Testosterone replacement therapy in patients with prostate cancer after radical prostatectomy. J Urol 2013; 190: 639-44.
    • (2013) J Urol , vol.190 , pp. 639-644
    • Pastuszak, A.W.1    Pearlman, A.M.2    Lai, W.S.3    Godoy, G.4    Sathyamoorthy, K.5
  • 114
    • 33846688614 scopus 로고    scopus 로고
    • Testosterone replacement for hypogonadism after treatment of early prostate cancer with brachytherapy
    • Sarosdy MF. Testosterone replacement for hypogonadism after treatment of early prostate cancer with brachytherapy. Cancer 2007; 109: 536-41.
    • (2007) Cancer , vol.109 , pp. 536-541
    • Sarosdy, M.F.1
  • 115
    • 84872489211 scopus 로고    scopus 로고
    • Testosterone replacement therapy in the setting of prostate cancer treated with radiation
    • Pastuszak AW, Pearlman AM, Godoy G, Miles BJ, Lipshultz LI, et al. Testosterone replacement therapy in the setting of prostate cancer treated with radiation. Int J Impot Res 2013; 25: 24-8.
    • (2013) Int J Impot Res , vol.25 , pp. 24-28
    • Pastuszak, A.W.1    Pearlman, A.M.2    Godoy, G.3    Miles, B.J.4    Lipshultz, L.I.5
  • 116
    • 29144469309 scopus 로고    scopus 로고
    • Adverse events associated with testosterone replacement in middle-aged and older men: A meta-analysis of randomized, placebo-controlled trials
    • Calof OM, Singh AB, Lee ML, Kenny AM, Urban RJ, et al. Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials. J Gerontol A Biol Sci Med Sci 2005; 60: 1451-7.
    • (2005) J Gerontol a Biol Sci Med Sci , vol.60 , pp. 1451-1457
    • Calof, O.M.1    Singh, A.B.2    Lee, M.L.3    Kenny, A.M.4    Urban, R.J.5
  • 117
    • 34547643044 scopus 로고    scopus 로고
    • Testosterone treatment to mimic hormone physiology in androgen replacement therapy. A view on testosterone gel and other preparations available
    • Fabbri A, Giannetta E, Lenzi A, Isidori AM. Testosterone treatment to mimic hormone physiology in androgen replacement therapy. A view on testosterone gel and other preparations available. Expert Opin Biol Ther 2007; 7: 1093-106.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 1093-1106
    • Fabbri, A.1    Giannetta, E.2    Lenzi, A.3    Isidori, A.M.4
  • 118
    • 4544289803 scopus 로고    scopus 로고
    • Androgen replacement therapy: Present and future
    • Gooren LJ, Bunck MC. Androgen replacement therapy: present and future. Drugs 2004; 64: 1861-91.
    • (2004) Drugs , vol.64 , pp. 1861-1891
    • Gooren, L.J.1    Bunck, M.C.2
  • 119
    • 4043134371 scopus 로고    scopus 로고
    • New testosterone buccal system (Striant) delivers physiological testosterone levels: Pharmacokinetics study in hypogonadal men
    • Wang C, Swerdloff R, Kipnes M, Matsumoto AM, Dobs AS, et al. New testosterone buccal system (Striant) delivers physiological testosterone levels: pharmacokinetics study in hypogonadal men. J Clin Endocrinol Metab 2004; 89: 3821-9.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3821-3829
    • Wang, C.1    Swerdloff, R.2    Kipnes, M.3    Matsumoto, A.M.4    Dobs, A.S.5
  • 121
    • 0033304555 scopus 로고    scopus 로고
    • Pharmacokinetics, efficacy, and safety of a permeation-enhanced testosterone transdermal system in comparison with bi-weekly injections of testosterone enanthate for the treatment of hypogonadal men
    • Dobs AS, Meikle AW, Arver S, Sanders SW, Caramelli KE, et al. Pharmacokinetics, efficacy, and safety of a permeation-enhanced testosterone transdermal system in comparison with bi-weekly injections of testosterone enanthate for the treatment of hypogonadal men. J Clin Endocrinol Metab 1999; 84: 3469-78.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3469-3478
    • Dobs, A.S.1    Meikle, A.W.2    Arver, S.3    Sanders, S.W.4    Caramelli, K.E.5
  • 123
    • 84856530228 scopus 로고    scopus 로고
    • A multi-institutional observational study of testosterone levels after testosterone pellet (Testopel(®)) insertion
    • McCullough AR, Khera M, Goldstein I, Hellstrom WJ, Morgentaler A, et al. A multi-institutional observational study of testosterone levels after testosterone pellet (Testopel(®)) insertion. J Sex Med 2012; 9: 594-601.
    • (2012) J Sex Med , vol.9 , pp. 594-601
    • McCullough, A.R.1    Khera, M.2    Goldstein, I.3    Hellstrom, W.J.4    Morgentaler, A.5
  • 124
    • 0034797564 scopus 로고    scopus 로고
    • Influence of implantation site and track geometry on the extrusion rate and pharmacology of testosterone implants
    • Kelleher S, Conway AJ, Handelsman DJ. Influence of implantation site and track geometry on the extrusion rate and pharmacology of testosterone implants. Clin Endocrinol (Oxf) 2001; 55: 531-6.
    • (2001) Clin Endocrinol (Oxf) , vol.55 , pp. 531-536
    • Kelleher, S.1    Conway, A.J.2    Handelsman, D.J.3
  • 125
    • 0029888841 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of subcutaneous testosterone implants in hypogonadal men
    • Jockenhövel F, Vogel E, Kreutzer M, Reinhardt W, Lederbogen S, et al. Pharmacokinetics and pharmacodynamics of subcutaneous testosterone implants in hypogonadal men. Clin Endocrinol (Oxf) 1996; 45: 61-71.
    • (1996) Clin Endocrinol (Oxf) , vol.45 , pp. 61-71
    • Jockenhövel, F.1    Vogel, E.2    Kreutzer, M.3    Reinhardt, W.4    Lederbogen, S.5
  • 126
    • 84874409333 scopus 로고    scopus 로고
    • Pharmacokinetic evaluation and dosing of subcutaneous testosterone pellets
    • Pastuszak AW, Mittakanti H, Liu JS, Gomez L, Lipshultz LI, et al. Pharmacokinetic evaluation and dosing of subcutaneous testosterone pellets. J Androl 2012; 33: 927-37.
    • (2012) J Androl , vol.33 , pp. 927-937
    • Pastuszak, A.W.1    Mittakanti, H.2    Liu, J.S.3    Gomez, L.4    Lipshultz, L.I.5
  • 127
    • 44249119426 scopus 로고    scopus 로고
    • Current and future testosterone delivery systems for treatment of the hypogonadal male
    • Pfeil E, Dobs AS. Current and future testosterone delivery systems for treatment of the hypogonadal male. Expert Opin Drug Deliv 2008; 5: 471-81.
    • (2008) Expert Opin Drug Deliv , vol.5 , pp. 471-481
    • Pfeil, E.1    Dobs, A.S.2
  • 128
    • 0033941520 scopus 로고    scopus 로고
    • Testosterone supplementation for erectile dysfunction: Results of a meta-analysis
    • Jain P, Rademaker AW, McVary KT. Testosterone supplementation for erectile dysfunction: results of a meta-analysis. J Urol 2000; 164: 371-5.
    • (2000) J Urol , vol.164 , pp. 371-375
    • Jain, P.1    Rademaker, A.W.2    McVary, K.T.3
  • 129
    • 0031799313 scopus 로고    scopus 로고
    • Use of topical corticosteroid pretreatment to reduce the incidence and severity of skin reactions associated with testosterone transdermal therapy
    • Wilson DE, Kaidbey K, Boike SC, Jorkasky DK. Use of topical corticosteroid pretreatment to reduce the incidence and severity of skin reactions associated with testosterone transdermal therapy. Clin Ther 1998; 20: 299-306.
    • (1998) Clin Ther , vol.20 , pp. 299-306
    • Wilson, D.E.1    Kaidbey, K.2    Boike, S.C.3    Jorkasky, D.K.4
  • 131
    • 0034453061 scopus 로고    scopus 로고
    • Pharmacokinetics of transdermal testosterone gel in hypogonadal men: Application of gel at one site versus four sites: A general clinical research center study
    • Wang C, Berman N, Longstreth JA, Chuapoco B, Hull L, et al. Pharmacokinetics of transdermal testosterone gel in hypogonadal men: application of gel at one site versus four sites: a general clinical research center study. J Clin Endocrinol Metab 2000; 85: 964-9.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 964-969
    • Wang, C.1    Berman, N.2    Longstreth, J.A.3    Chuapoco, B.4    Hull, L.5
  • 132
    • 0036274222 scopus 로고    scopus 로고
    • Interpersonal testosterone transfer after topical application of a newly developed testosterone gel preparation
    • Rolf C, Knie U, Lemmnitz G, Nieschlag E. Interpersonal testosterone transfer after topical application of a newly developed testosterone gel preparation. Clin Endocrinol (Oxf) 2002; 56: 637-41.
    • (2002) Clin Endocrinol (Oxf) , vol.56 , pp. 637-641
    • Rolf, C.1    Knie, U.2    Lemmnitz, G.3    Nieschlag, E.4
  • 133
    • 40649125607 scopus 로고    scopus 로고
    • Efficacy of changing testosterone gel preparations (Androgel or Testim) among suboptimally responsive hypogonadal men
    • Grober ED, Khera M, Soni SD, Espinoza MG, Lipshultz LI. Efficacy of changing testosterone gel preparations (Androgel or Testim) among suboptimally responsive hypogonadal men. Int J Impot Res 2008; 20: 213-7.
    • (2008) Int J Impot Res , vol.20 , pp. 213-217
    • Grober, E.D.1    Khera, M.2    Soni, S.D.3    Espinoza, M.G.4    Lipshultz, L.I.5
  • 134
    • 63249093111 scopus 로고    scopus 로고
    • Testosterone supplementation for hypogonadal men by the nasal route
    • Mattern C, Hoffmann C, Morley JE, Badiu C. Testosterone supplementation for hypogonadal men by the nasal route. Aging Male 2008; 11: 171-8.
    • (2008) Aging Male , vol.11 , pp. 171-178
    • Mattern, C.1    Hoffmann, C.2    Morley, J.E.3    Badiu, C.4
  • 135
    • 84924681222 scopus 로고    scopus 로고
    • Reference ID: 3514261. Available from
    • Natesto (testosterone) nasal gel. Reference ID: 3514261. Available from: http://www.accessdata.fda.gov/drugsatfda-docs/label/2014/205488s000lbl.
    • Natesto (Testosterone) Nasal Gel
  • 136
    • 0034970468 scopus 로고    scopus 로고
    • The effect of aromatase inhibition on sex steroids, gonadotropins, and markers of bone turnover in older men
    • Taxel P, Kennedy DG, Fall PM, Willard AK, Clive JM, et al. The effect of aromatase inhibition on sex steroids, gonadotropins, and markers of bone turnover in older men. J Clin Endocrinol Metab 2001; 86: 2869-74.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2869-2874
    • Taxel, P.1    Kennedy, D.G.2    Fall, P.M.3    Willard, A.K.4    Clive, J.M.5
  • 137
    • 0036144667 scopus 로고    scopus 로고
    • Aromatase inhibitors for male infertility
    • Raman JD, Schlegel PN. Aromatase inhibitors for male infertility. J Urol 2002; 167: 624-9.
    • (2002) J Urol , vol.167 , pp. 624-629
    • Raman, J.D.1    Schlegel, P.N.2
  • 138
    • 1642364154 scopus 로고    scopus 로고
    • Effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels
    • Leder BZ, Rohrer JL, Rubin SD, Gallo J, Longcope C. Effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels. J Clin Endocrinol Metab 2004; 89: 1174-80.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1174-1180
    • Leder, B.Z.1    Rohrer, J.L.2    Rubin, S.D.3    Gallo, J.4    Longcope, C.5
  • 139
    • 0036317130 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physical function and activity in older men with partial age-related androgen deficiency
    • Liu PY, Wishart SM, Handelsman DJ. A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physical function and activity in older men with partial age-related androgen deficiency. J Clin Endocrinol Metab 2002; 87: 3125-35.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3125-3135
    • Liu, P.Y.1    Wishart, S.M.2    Handelsman, D.J.3
  • 140
    • 84872145118 scopus 로고    scopus 로고
    • Concomitant intramuscular human chorionic gonadotropin preserves spermatogenesis in men undergoing testosterone replacement therapy
    • Hsieh TC, Pastuszak AW, Hwang K, Lipshultz LI. Concomitant intramuscular human chorionic gonadotropin preserves spermatogenesis in men undergoing testosterone replacement therapy. J Urol 2013; 189: 647-50.
    • (2013) J Urol , vol.189 , pp. 647-650
    • Hsieh, T.C.1    Pastuszak, A.W.2    Hwang, K.3    Lipshultz, L.I.4
  • 141
    • 84864482613 scopus 로고    scopus 로고
    • Outcomes of clomiphene citrate treatment in young hypogonadal men
    • Katz DJ, Nabulsi O, Tal R, Mulhall JP. Outcomes of clomiphene citrate treatment in young hypogonadal men. BJU Int 2012; 110: 573-8.
    • (2012) BJU Int , vol.110 , pp. 573-578
    • Katz, D.J.1    Nabulsi, O.2    Tal, R.3    Mulhall, J.P.4
  • 142
    • 84868206038 scopus 로고    scopus 로고
    • Clomiphene citrate is safe and effective for long-term management of hypogonadism
    • Moskovic DJ, Katz DJ, Akhavan A, Park K, Mulhall JP. Clomiphene citrate is safe and effective for long-term management of hypogonadism. BJU Int 2012; 110: 1524-8.
    • (2012) BJU Int , vol.110 , pp. 1524-1528
    • Moskovic, D.J.1    Katz, D.J.2    Akhavan, A.3    Park, K.4    Mulhall, J.P.5
  • 143
    • 84906098883 scopus 로고    scopus 로고
    • Testosterone supplementation versus clomiphene citrate for hypogonadism: An age matched comparison of satisfaction and efficacy
    • Ramasamy R, Scovell JM, Kovac JR, Lipshultz LI. Testosterone supplementation versus clomiphene citrate for hypogonadism: an age matched comparison of satisfaction and efficacy. J Urol 2014; 192: 875-9.
    • (2014) J Urol , vol.192 , pp. 875-879
    • Ramasamy, R.1    Scovell, J.M.2    Kovac, J.R.3    Lipshultz, L.I.4
  • 144
    • 72249096282 scopus 로고    scopus 로고
    • Clomiphene citrate and enclomiphene for the treatment of hypogonadal androgen deficiency
    • Kaminetsky J, Hemani ML. Clomiphene citrate and enclomiphene for the treatment of hypogonadal androgen deficiency. Expert Opin Investig Drugs 2009; 18: 1947-55.
    • (2009) Expert Opin Investig Drugs , vol.18 , pp. 1947-1955
    • Kaminetsky, J.1    Hemani, M.L.2
  • 145
    • 84878686321 scopus 로고    scopus 로고
    • Oral enclomiphene citrate stimulates the endogenous production of testosterone and sperm counts in men with low testosterone: Comparison with testosterone gel
    • Kaminetsky J, Werner M, Fontenot G, Wiehle RD. Oral enclomiphene citrate stimulates the endogenous production of testosterone and sperm counts in men with low testosterone: comparison with testosterone gel. J Sex Med 2013; 10: 1628-35.
    • (2013) J Sex Med , vol.10 , pp. 1628-1635
    • Kaminetsky, J.1    Werner, M.2    Fontenot, G.3    Wiehle, R.D.4
  • 147
    • 80054827093 scopus 로고    scopus 로고
    • Onset of effects of testosterone treatment and time span until maximum effects are achieved
    • Saad F, Aversa A, Isidori AM, Zafalon L, Zitzmann M, et al. Onset of effects of testosterone treatment and time span until maximum effects are achieved. Eur J Endocrinol 2011; 165: 675-85.
    • (2011) Eur J Endocrinol , vol.165 , pp. 675-685
    • Saad, F.1    Aversa, A.2    Isidori, A.M.3    Zafalon, L.4    Zitzmann, M.5
  • 148
    • 64249137805 scopus 로고    scopus 로고
    • Prostate-specific antigen changes and prostate cancer in hypogonadal men treated with testosterone replacement therapy
    • Coward RM, Simhan J, Carson CC 3rd. Prostate-specific antigen changes and prostate cancer in hypogonadal men treated with testosterone replacement therapy. BJU Int 2009; 103: 1179-83.
    • (2009) BJU Int , vol.103 , pp. 1179-1183
    • Coward, R.M.1    Simhan, J.2    Carson, C.C.3
  • 149
    • 0242390083 scopus 로고    scopus 로고
    • Managing the risks of prostate disease during testosterone replacement therapy in older men: Recommendations for a standardized monitoring plan
    • Bhasin S, Singh AB, Mac RP, Carter B, Lee MI, et al. Managing the risks of prostate disease during testosterone replacement therapy in older men: recommendations for a standardized monitoring plan. J Androl 2003; 24: 299-311.
    • (2003) J Androl , vol.24 , pp. 299-311
    • Bhasin, S.1    Singh, A.B.2    Mac, R.P.3    Carter, B.4    Lee, M.I.5
  • 150
    • 8844263744 scopus 로고    scopus 로고
    • Risks of testosterone replacement therapy in ageing men
    • Tan RS, Salazar JA. Risks of testosterone replacement therapy in ageing men. Expert Opin Drug Saf 2004; 3: 599-606.
    • (2004) Expert Opin Drug Saf , vol.3 , pp. 599-606
    • Tan, R.S.1    Salazar, J.A.2


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