메뉴 건너뛰기




Volumn 48, Issue 2, 2015, Pages 137-146

Increased CD4+CD25+ regulatory T cells correlate with poor short-term outcomes in hepatitis B virus-related acute-on-chronic liver failure patients

Author keywords

Chronic hepatitis B; Forkhead winged helix transcription factor; Immune response; Liver failure; Regulatory T cell

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3; VIRUS DNA; CD4 ANTIGEN; IL10 PROTEIN, HUMAN; IL2RA PROTEIN, HUMAN; INTERLEUKIN 2 RECEPTOR ALPHA;

EID: 84924582944     PISSN: 16841182     EISSN: 19959133     Source Type: Journal    
DOI: 10.1016/j.jmii.2013.11.001     Document Type: Article
Times cited : (15)

References (37)
  • 1
    • 0036385207 scopus 로고    scopus 로고
    • The pathophysiological basis of acute-on-chronic liver failure
    • Sen S., Williams R., Jalan R. The pathophysiological basis of acute-on-chronic liver failure. Liver 2002, 22(Suppl. 2):5-13.
    • (2002) Liver , vol.22 , pp. 5-13
    • Sen, S.1    Williams, R.2    Jalan, R.3
  • 2
    • 59749098468 scopus 로고    scopus 로고
    • Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL)
    • Sarin S.K., Kumar A., Almeida J.A., Chawla Y.K., Fan S.T., Garg H., et al. Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL). Hepatol Int 2009, 3:269-282.
    • (2009) Hepatol Int , vol.3 , pp. 269-282
    • Sarin, S.K.1    Kumar, A.2    Almeida, J.A.3    Chawla, Y.K.4    Fan, S.T.5    Garg, H.6
  • 3
    • 0142242240 scopus 로고    scopus 로고
    • Discriminant function for prognostic indexes and probability of death in chronic severe hepatitis B
    • Ke W.M., Ye Y.N., Huang S. Discriminant function for prognostic indexes and probability of death in chronic severe hepatitis B. J Gastroenterol 2003, 38:861-864.
    • (2003) J Gastroenterol , vol.38 , pp. 861-864
    • Ke, W.M.1    Ye, Y.N.2    Huang, S.3
  • 4
    • 38349086657 scopus 로고    scopus 로고
    • A winning war against hepatitis B virus infection in China
    • Jia J.D., Zhuang H. A winning war against hepatitis B virus infection in China. Chin Med J (Engl) 2007, 120:2157-2158.
    • (2007) Chin Med J (Engl) , vol.120 , pp. 2157-2158
    • Jia, J.D.1    Zhuang, H.2
  • 6
    • 0242268932 scopus 로고    scopus 로고
    • Live-donor liver transplantation for acute-on-chronic hepatitis B liver failure
    • Liu C.L., Fan S.T., Lo C.M., Wei W.I., Yong B.H., Lai C.L., et al. Live-donor liver transplantation for acute-on-chronic hepatitis B liver failure. Transplantation 2003, 76:1174-1179.
    • (2003) Transplantation , vol.76 , pp. 1174-1179
    • Liu, C.L.1    Fan, S.T.2    Lo, C.M.3    Wei, W.I.4    Yong, B.H.5    Lai, C.L.6
  • 7
    • 16844369607 scopus 로고    scopus 로고
    • Natural regulatory T cells in infectious disease
    • Belkaid Y., Rouse B.T. Natural regulatory T cells in infectious disease. Nat Immunol 2005, 6:353-360.
    • (2005) Nat Immunol , vol.6 , pp. 353-360
    • Belkaid, Y.1    Rouse, B.T.2
  • 8
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005, 6:345-352.
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 10
    • 34247277666 scopus 로고    scopus 로고
    • Foxp3 in control of the regulatory T cell lineage
    • Zheng Y., Rudensky A.Y. Foxp3 in control of the regulatory T cell lineage. Nat Immunol 2007, 8:457-462.
    • (2007) Nat Immunol , vol.8 , pp. 457-462
    • Zheng, Y.1    Rudensky, A.Y.2
  • 11
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S., Nomura T., Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003, 299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 12
    • 16244385911 scopus 로고    scopus 로고
    • Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection
    • Stoop J.N., van der Molen R.G., Baan C.C., van der Laan L.J., Kuipers E.J., Kusters J.G., et al. Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection. Hepatology 2005, 41:771-778.
    • (2005) Hepatology , vol.41 , pp. 771-778
    • Stoop, J.N.1    van der Molen, R.G.2    Baan, C.C.3    van der Laan, L.J.4    Kuipers, E.J.5    Kusters, J.G.6
  • 13
    • 37149016672 scopus 로고    scopus 로고
    • Circulating CD4+CD25+ regulatory T cells correlate with chronic hepatitis B infection
    • Peng G., Li S., Wu W., Sun Z., Chen Y., Chen Z. Circulating CD4+CD25+ regulatory T cells correlate with chronic hepatitis B infection. Immunology 2008, 123:57-65.
    • (2008) Immunology , vol.123 , pp. 57-65
    • Peng, G.1    Li, S.2    Wu, W.3    Sun, Z.4    Chen, Y.5    Chen, Z.6
  • 14
    • 33846600414 scopus 로고    scopus 로고
    • Association of CD4+CD25+Foxp3+ regulatory T cells with chronic activity and viral clearance in patients with hepatitis B
    • Yang G., Liu A., Xie Q., Guo T.B., Wan B., Zhou B., et al. Association of CD4+CD25+Foxp3+ regulatory T cells with chronic activity and viral clearance in patients with hepatitis B. Int Immunol 2007, 19:133-140.
    • (2007) Int Immunol , vol.19 , pp. 133-140
    • Yang, G.1    Liu, A.2    Xie, Q.3    Guo, T.B.4    Wan, B.5    Zhou, B.6
  • 15
    • 76449096344 scopus 로고    scopus 로고
    • Circulating CD4+CD25high regulatory T cells and expression of PD-1 and BTLA on CD4+ T cells in patients with chronic hepatitis B virus infection
    • Nan X.P., Zhang Y., Yu H.T., Li Y., Sun R.L., Wang J.P., et al. Circulating CD4+CD25high regulatory T cells and expression of PD-1 and BTLA on CD4+ T cells in patients with chronic hepatitis B virus infection. Viral Immunol 2010, 23:63-70.
    • (2010) Viral Immunol , vol.23 , pp. 63-70
    • Nan, X.P.1    Zhang, Y.2    Yu, H.T.3    Li, Y.4    Sun, R.L.5    Wang, J.P.6
  • 16
    • 33745323050 scopus 로고    scopus 로고
    • Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B
    • Xu D., Fu J., Jin L., Zhang H., Zhou C., Zou Z., et al. Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B. J Immunol 2006, 177:739-747.
    • (2006) J Immunol , vol.177 , pp. 739-747
    • Xu, D.1    Fu, J.2    Jin, L.3    Zhang, H.4    Zhou, C.5    Zou, Z.6
  • 17
    • 2142643604 scopus 로고    scopus 로고
    • Control of immune pathology by regulatory T cells
    • discussion 98-105, 106-114
    • Powrie F., Read S., Mottet C., Uhlig H., Maloy K. Control of immune pathology by regulatory T cells. Novartis Found Symp 2003, 252:92-98. discussion 98-105, 106-114.
    • (2003) Novartis Found Symp , vol.252 , pp. 92-98
    • Powrie, F.1    Read, S.2    Mottet, C.3    Uhlig, H.4    Maloy, K.5
  • 18
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • Maloy K.J., Powrie F. Regulatory T cells in the control of immune pathology. Nat Immunol 2001, 2:816-822.
    • (2001) Nat Immunol , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 19
    • 33845512361 scopus 로고    scopus 로고
    • Altered immune function of monocytes in different stages of patients with acute on chronic liver failure
    • Xing T., Li L., Cao H., Huang J. Altered immune function of monocytes in different stages of patients with acute on chronic liver failure. Clin Exp Immunol 2007, 147:184-188.
    • (2007) Clin Exp Immunol , vol.147 , pp. 184-188
    • Xing, T.1    Li, L.2    Cao, H.3    Huang, J.4
  • 20
    • 64749115624 scopus 로고    scopus 로고
    • Imbalanced intrahepatic cytokine expression of interferon-gamma, tumor necrosis factor-alpha, and interleukin-10 in patients with acute-on-chronic liver failure associated with hepatitis B virus infection
    • Zou Z., Li B., Xu D., Zhang Z., Zhao J.M., Zhou G., et al. Imbalanced intrahepatic cytokine expression of interferon-gamma, tumor necrosis factor-alpha, and interleukin-10 in patients with acute-on-chronic liver failure associated with hepatitis B virus infection. J Clin Gastroenterol 2009, 43:182-190.
    • (2009) J Clin Gastroenterol , vol.43 , pp. 182-190
    • Zou, Z.1    Li, B.2    Xu, D.3    Zhang, Z.4    Zhao, J.M.5    Zhou, G.6
  • 21
    • 78049234709 scopus 로고    scopus 로고
    • Skewed ratios between CD3(+) T cells and monocytes are associated with poor prognosis in patients with HBV-related acute-on-chronic liver failure
    • Shi F., Zhang J.Y., Zeng Z., Tien P., Wang F.S. Skewed ratios between CD3(+) T cells and monocytes are associated with poor prognosis in patients with HBV-related acute-on-chronic liver failure. Biochem Biophys Res Commun 2010, 402:30-36.
    • (2010) Biochem Biophys Res Commun , vol.402 , pp. 30-36
    • Shi, F.1    Zhang, J.Y.2    Zeng, Z.3    Tien, P.4    Wang, F.S.5
  • 22
    • 70449705835 scopus 로고    scopus 로고
    • Impaired TLR3/IFN-beta signaling in monocyte-derived dendritic cells from patients with acute-on-chronic hepatitis B liver failure: relevance to the severity of liver damage
    • Li N., Li Q., Qian Z., Zhang Y., Chen M., Shi G. Impaired TLR3/IFN-beta signaling in monocyte-derived dendritic cells from patients with acute-on-chronic hepatitis B liver failure: relevance to the severity of liver damage. Biochem Biophys Res Commun 2009, 390:630-635.
    • (2009) Biochem Biophys Res Commun , vol.390 , pp. 630-635
    • Li, N.1    Li, Q.2    Qian, Z.3    Zhang, Y.4    Chen, M.5    Shi, G.6
  • 23
    • 73949112938 scopus 로고    scopus 로고
    • Increased killing of liver NK cells by Fas/Fas ligand and NKG2D/NKG2D ligand contributes to hepatocyte necrosis in virus-induced liver failure
    • Zou Y., Chen T., Han M., Wang H., Yan W., Song G., et al. Increased killing of liver NK cells by Fas/Fas ligand and NKG2D/NKG2D ligand contributes to hepatocyte necrosis in virus-induced liver failure. J Immunol 2010, 184:466-475.
    • (2010) J Immunol , vol.184 , pp. 466-475
    • Zou, Y.1    Chen, T.2    Han, M.3    Wang, H.4    Yan, W.5    Song, G.6
  • 24
    • 78249287837 scopus 로고    scopus 로고
    • High mobility group box-1 protein inhibits regulatory T cell immune activity in liver failure in patients with chronic hepatitis B
    • Wang L.W., Chen H., Gong Z.J. High mobility group box-1 protein inhibits regulatory T cell immune activity in liver failure in patients with chronic hepatitis B. Hepatobiliary Pancreat Dis Int 2010, 9:499-507.
    • (2010) Hepatobiliary Pancreat Dis Int , vol.9 , pp. 499-507
    • Wang, L.W.1    Chen, H.2    Gong, Z.J.3
  • 25
    • 77953826461 scopus 로고    scopus 로고
    • Diagnostic and treatment guidelines for liver failure
    • Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical Association; Severe Liver Diseases and Artificial Liver Group, Chinese Society of Hepatology, Chinese Medical Association, [In Chinese]
    • Diagnostic and treatment guidelines for liver failure. Zhonghua Gan Zang Bing Za Zhi 2006, 14:643-646. Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical Association; Severe Liver Diseases and Artificial Liver Group, Chinese Society of Hepatology, Chinese Medical Association, [In Chinese].
    • (2006) Zhonghua Gan Zang Bing Za Zhi , vol.14 , pp. 643-646
  • 26
    • 69449094592 scopus 로고    scopus 로고
    • PTEN expression is down-regulated in liver tissues of rats with hepatic fibrosis induced by biliary stenosis
    • Hao L.S., Zhang X.L., An J.Y., Karlin J., Tian X.P., Dun Z.N., et al. PTEN expression is down-regulated in liver tissues of rats with hepatic fibrosis induced by biliary stenosis. APMIS 2009, 117:681-691.
    • (2009) APMIS , vol.117 , pp. 681-691
    • Hao, L.S.1    Zhang, X.L.2    An, J.Y.3    Karlin, J.4    Tian, X.P.5    Dun, Z.N.6
  • 27
    • 54849146600 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Dienstag J.L. Hepatitis B virus infection. N Engl J Med 2008, 359:1486-1500.
    • (2008) N Engl J Med , vol.359 , pp. 1486-1500
    • Dienstag, J.L.1
  • 28
    • 84924621304 scopus 로고    scopus 로고
    • Advances on immunopathogenesis of chronic severe hepatitis B
    • Shen C., Zhao C.Y. Advances on immunopathogenesis of chronic severe hepatitis B. Zhonghua Chuan Ran Bing Za Zhi 2011, 29:573-576.
    • (2011) Zhonghua Chuan Ran Bing Za Zhi , vol.29 , pp. 573-576
    • Shen, C.1    Zhao, C.Y.2
  • 29
    • 77955477946 scopus 로고    scopus 로고
    • Regulation of HBV transcription and replication and severe acute exacerbation of chronic hepatitis B
    • [In Chinese]
    • Tang H., Chen E.Q. Regulation of HBV transcription and replication and severe acute exacerbation of chronic hepatitis B. Zhonghua Gan Zang Bing Za Zhi 2010, 18:243-245. [In Chinese].
    • (2010) Zhonghua Gan Zang Bing Za Zhi , vol.18 , pp. 243-245
    • Tang, H.1    Chen, E.Q.2
  • 31
    • 0037261145 scopus 로고    scopus 로고
    • Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis
    • Cao D., Malmstrom V., Baecher-Allan C., Hafler D., Klareskog L., Trollmo C. Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis. Eur J Immunol 2003, 33:215-223.
    • (2003) Eur J Immunol , vol.33 , pp. 215-223
    • Cao, D.1    Malmstrom, V.2    Baecher-Allan, C.3    Hafler, D.4    Klareskog, L.5    Trollmo, C.6
  • 32
    • 34249309861 scopus 로고    scopus 로고
    • Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis
    • Yu Q.T., Saruta M., Avanesyan A., Fleshner P.R., Banham A.H., Papadakis K.A. Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis. Inflamm Bowel Dis 2007, 13:191-199.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 191-199
    • Yu, Q.T.1    Saruta, M.2    Avanesyan, A.3    Fleshner, P.R.4    Banham, A.H.5    Papadakis, K.A.6
  • 33
    • 64749102802 scopus 로고    scopus 로고
    • Study of liver-targeted regulatory T cells in hepatitis B and C virus in chronically infected patients
    • Miyaaki H., Zhou H., Ichikawa T., Nakao K., Shibata H., Takeshita S., et al. Study of liver-targeted regulatory T cells in hepatitis B and C virus in chronically infected patients. Liver Int 2009, 29:702-707.
    • (2009) Liver Int , vol.29 , pp. 702-707
    • Miyaaki, H.1    Zhou, H.2    Ichikawa, T.3    Nakao, K.4    Shibata, H.5    Takeshita, S.6
  • 34
    • 34547604820 scopus 로고    scopus 로고
    • Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection
    • Ward S.M., Fox B.C., Brown P.J., Worthington J., Fox S.B., Chapman R.W., et al. Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection. J Hepatol 2007, 47:316-324.
    • (2007) J Hepatol , vol.47 , pp. 316-324
    • Ward, S.M.1    Fox, B.C.2    Brown, P.J.3    Worthington, J.4    Fox, S.B.5    Chapman, R.W.6
  • 35
    • 58149382669 scopus 로고    scopus 로고
    • Local accumulation and activation of regulatory Foxp3+CD4 T(R) cells accompanies the appearance of activated CD8 T cells in the liver
    • Bochtler P., Riedl P., Gomez I., Schirmbeck R., Reimann J. Local accumulation and activation of regulatory Foxp3+CD4 T(R) cells accompanies the appearance of activated CD8 T cells in the liver. Hepatology 2008, 48:1954-1963.
    • (2008) Hepatology , vol.48 , pp. 1954-1963
    • Bochtler, P.1    Riedl, P.2    Gomez, I.3    Schirmbeck, R.4    Reimann, J.5
  • 36
    • 35949001284 scopus 로고    scopus 로고
    • Interferon-gamma exacerbates liver damage, the hepatic progenitor cell response and fibrosis in a mouse model of chronic liver injury
    • Knight B., Lim R., Yeoh G.C., Olynyk J.K. Interferon-gamma exacerbates liver damage, the hepatic progenitor cell response and fibrosis in a mouse model of chronic liver injury. J Hepatol 2007, 47:826-833.
    • (2007) J Hepatol , vol.47 , pp. 826-833
    • Knight, B.1    Lim, R.2    Yeoh, G.C.3    Olynyk, J.K.4
  • 37
    • 15444363618 scopus 로고    scopus 로고
    • Depletion of regulatory T cells in HIV infection is associated with immune activation
    • Eggena M.P., Barugahare B., Jones N., Okello M., Mutalya S., Kityo C., et al. Depletion of regulatory T cells in HIV infection is associated with immune activation. J Immunol 2005, 174:4407-4414.
    • (2005) J Immunol , vol.174 , pp. 4407-4414
    • Eggena, M.P.1    Barugahare, B.2    Jones, N.3    Okello, M.4    Mutalya, S.5    Kityo, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.