-
1
-
-
79957673711
-
IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer
-
Neurath MF, Finotto S: IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer. Cytokine Growth Factor Rev 22: 83-89, 2011
-
(2011)
Cytokine Growth Factor Rev
, vol.22
, pp. 83-89
-
-
Neurath, M.F.1
Finotto, S.2
-
2
-
-
17644368573
-
Interleukin-6: Frombasic science to medicine-40 years in immunology
-
Kishimoto T: Interleukin-6: Frombasic science to medicine-40 years in immunology. Annu Rev Immunol 23: 1-21, 2005
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 1-21
-
-
Kishimoto, T.1
-
3
-
-
79955650634
-
The pro-and antiinflammatory properties of the cytokine interleukin-6
-
Scheller J, Chalaris A, Schmidt-Arras D, Rose-John S: The pro-and antiinflammatory properties of the cytokine interleukin-6. Biochim Biophys Acta 1813: 878-888, 2011
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 878-888
-
-
Scheller, J.1
Chalaris, A.2
Schmidt-Arras, D.3
Rose-John, S.4
-
4
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
Taga T, Kishimoto T: Gp130 and the interleukin-6 family of cytokines. Annu Rev Immunol 15: 797-819, 1997
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
5
-
-
1642578987
-
IL-6 trans-signaling: The heat is on
-
Rose-John S, NeurathMF: IL-6 trans-signaling: The heat is on. Immunity 20: 2-4, 2004
-
(2004)
Immunity
, vol.20
, pp. 2-4
-
-
Rose-John, S.1
Neurath, M.F.2
-
6
-
-
33748848714
-
Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: Role in inflammation and cancer
-
Rose-John S, Scheller J, Elson G, Jones SA: Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: Role in inflammation and cancer. J Leukoc Biol 80: 227-236, 2006
-
(2006)
J Leukoc Biol
, vol.80
, pp. 227-236
-
-
Rose-John, S.1
Scheller, J.2
Elson, G.3
Jones, S.A.4
-
7
-
-
80052358980
-
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
-
Jones SA, Scheller J, Rose-John S: Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling. J Clin Invest 121: 3375-3383, 2011
-
(2011)
J Clin Invest
, vol.121
, pp. 3375-3383
-
-
Jones, S.A.1
Scheller, J.2
Rose-John, S.3
-
8
-
-
0022499547
-
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin
-
Hirano T, Yasukawa K, Harada H, Taga T, Watanabe Y, Matsuda T, Kashiwamura S, Nakajima K, Koyama K, Iwamatsu A, Tsunasawa S, Sakiyama F, Matsui H, Takahara Y, Taniguchi T, Kishimoto T: Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature 324: 73-76, 1986
-
(1986)
Nature
, vol.324
, pp. 73-76
-
-
Hirano, T.1
Yasukawa, K.2
Harada, H.3
Taga, T.4
Watanabe, Y.5
Matsuda, T.6
Kashiwamura, S.7
Nakajima, K.8
Koyama, K.9
Iwamatsu, A.10
Tsunasawa, S.11
Sakiyama, F.12
Matsui, H.13
Takahara, Y.14
Taniguchi, T.15
Kishimoto, T.16
-
9
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effectorTH17andregulatoryTcells
-
Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK: Reciprocal developmental pathways for the generation of pathogenic effectorTH17andregulatoryTcells.Nature 441: 235-238, 2006
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
10
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L, Ivanov II, Spolski R, Min R, Shenderov K, Egawa T, Levy DE, Leonard WJ, Littman DR: IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 8: 967-974, 2007
-
(2007)
Nat Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
Min, R.4
Shenderov, K.5
Egawa, T.6
Levy, D.E.7
Leonard, W.J.8
Littman, D.R.9
-
11
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan PR, Harrington LE, O'Quinn DB, HelmsWS, Bullard DC, Elson CO,Hatton RD,Wahl SM, Schoeb TR,WeaverCT: Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 441: 231-234, 2006
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
Hatton, R.D.7
Wahl, S.M.8
Schoeb, T.R.9
Weaver, C.T.10
-
12
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
VeldhoenM, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B: TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24: 179-189, 2006
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
13
-
-
48249148236
-
IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis
-
Serada S, FujimotoM,MiharaM, KoikeN,Ohsugi Y, Nomura S, Yoshida H, Nishikawa T, Terabe F,Ohkawara T, Takahashi T, Ripley B, Kimura A, Kishimoto T, Naka T: IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 105: 9041-9046, 2008
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9041-9046
-
-
Serada, S.1
Fujimoto, M.2
Mihara, M.3
Koike, N.4
Ohsugi, Y.5
Nomura, S.6
Yoshida, H.7
Nishikawa, T.8
Terabe, F.9
Ohkawara, T.10
Takahashi, T.11
Ripley, B.12
Kimura, A.13
Kishimoto, T.14
Naka, T.15
-
14
-
-
0034193039
-
IL-6 is required for the development of Th1 cell-mediated murine colitis
-
Yamamoto M, Yoshizaki K, Kishimoto T, Ito H: IL-6 is required for the development of Th1 cell-mediated murine colitis. J Immunol 164: 4878-4882, 2000
-
(2000)
J Immunol
, vol.164
, pp. 4878-4882
-
-
Yamamoto, M.1
Yoshizaki, K.2
Kishimoto, T.3
Ito, H.4
-
15
-
-
57349083145
-
Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses
-
Fujimoto M, Serada S, Mihara M, Uchiyama Y, Yoshida H, Koike N, Ohsugi Y, Nishikawa T, Ripley B, Kimura A, Kishimoto T, Naka T: Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses. Arthritis Rheum 58: 3710-3719, 2008
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3710-3719
-
-
Fujimoto, M.1
Serada, S.2
Mihara, M.3
Uchiyama, Y.4
Yoshida, H.5
Koike, N.6
Ohsugi, Y.7
Nishikawa, T.8
Ripley, B.9
Kimura, A.10
Kishimoto, T.11
Naka, T.12
-
16
-
-
81755184476
-
Anti-interleukin-6 receptor antibody, tocilizumab, for the treatment of autoimmune diseases
-
Tanaka T, Narazaki M, Kishimoto T: Anti-interleukin-6 receptor antibody, tocilizumab, for the treatment of autoimmune diseases. FEBS Lett 585: 3699-3709, 2011
-
(2011)
FEBS Lett
, vol.585
, pp. 3699-3709
-
-
Tanaka, T.1
Narazaki, M.2
Kishimoto, T.3
-
17
-
-
84874403935
-
Blocking the effects of interleukin-6 in rheumatoid arthritis and other inflammatory rheumatic diseases: Systematic literature review and meta-analysis informing a consensus statement
-
Schoels MM, van der Heijde D, Breedveld FC, Burmester GR, Dougados M, Emery P, Ferraccioli G, Gabay C, Gibofsky A, Gomez-Reino JJ, Jones G, Kvien TK, Murakami M, Nishimoto N, Smolen JS: Blocking the effects of interleukin-6 in rheumatoid arthritis and other inflammatory rheumatic diseases: Systematic literature review and meta-analysis informing a consensus statement. Ann Rheum Dis 72: 583-589, 2013
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 583-589
-
-
Schoels, M.M.1
Van Der Heijde, D.2
Breedveld, F.C.3
Burmester, G.R.4
Dougados, M.5
Emery, P.6
Ferraccioli, G.7
Gabay, C.8
Gibofsky, A.9
Gomez-Reino, J.J.10
Jones, G.11
Kvien, T.K.12
Murakami, M.13
Nishimoto, N.14
Smolen, J.S.15
-
18
-
-
84896495791
-
A new era for the treatment of inflammatory autoimmune diseases by interleukin-6 blockade strategy
-
Tanaka T, Narazaki M, Ogata A, Kishimoto T: A new era for the treatment of inflammatory autoimmune diseases by interleukin-6 blockade strategy. Semin Immunol 26: 88-96, 2014
-
(2014)
Semin Immunol
, vol.26
, pp. 88-96
-
-
Tanaka, T.1
Narazaki, M.2
Ogata, A.3
Kishimoto, T.4
-
19
-
-
0024404853
-
IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice
-
Aderka D, Le JM, Vilcek J: IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice. J Immunol 143: 3517-3523, 1989
-
(1989)
J Immunol
, vol.143
, pp. 3517-3523
-
-
Aderka, D.1
Le, J.M.2
Vilcek, J.3
-
20
-
-
0025805971
-
Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammation
-
Ulich TR, Yin S, Guo K, Yi ES, Remick D, del Castillo J: Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammation. Am J Pathol 138: 1097-1101, 1991
-
(1991)
Am J Pathol
, vol.138
, pp. 1097-1101
-
-
Ulich, T.R.1
Yin, S.2
Guo, K.3
Yi, E.S.4
Remick, D.5
Del Castillo, J.6
-
21
-
-
0025802831
-
Endotoxin-induced cytokine gene expression in vivo. III. IL-6 mRNA and serum protein expression and the in vivo hematologic effects of IL-6
-
Ulich TR, Guo KZ, Remick D, del Castillo J, Yin SM: Endotoxin-induced cytokine gene expression in vivo. III. IL-6 mRNA and serum protein expression and the in vivo hematologic effects of IL-6. J Immunol 146: 2316-2323, 1991
-
(1991)
J Immunol
, vol.146
, pp. 2316-2323
-
-
Ulich, T.R.1
Guo, K.Z.2
Remick, D.3
Del Castillo, J.4
Yin, S.M.5
-
22
-
-
0032518415
-
IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses
-
Xing Z, Gauldie J, Cox G, Baumann H, Jordana M, Lei XF, Achong MK: IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. J Clin Invest 101: 311-320, 1998
-
(1998)
J Clin Invest
, vol.101
, pp. 311-320
-
-
Xing, Z.1
Gauldie, J.2
Cox, G.3
Baumann, H.4
Jordana, M.5
Lei, X.F.6
Achong, M.K.7
-
23
-
-
0026667576
-
Inhibitory role of interleukin-6 in macrophage proliferation
-
Riedy MC, Stewart CC: Inhibitory role of interleukin-6 in macrophage proliferation. J Leukoc Biol 52: 125-127, 1992
-
(1992)
J Leukoc Biol
, vol.52
, pp. 125-127
-
-
Riedy, M.C.1
Stewart, C.C.2
-
24
-
-
0028031990
-
Interleukin-6 (IL-6) as an anti-inflammatory cytokine: Induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55
-
Tilg H, Trehu E, Atkins MB, Dinarello CA,Mier JW: Interleukin-6 (IL-6) as an anti-inflammatory cytokine: Induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55. Blood 83: 113-118, 1994
-
(1994)
Blood
, vol.83
, pp. 113-118
-
-
Tilg, H.1
Trehu, E.2
Atkins, M.B.3
Dinarello, C.A.4
Mier, J.W.5
-
25
-
-
0033802096
-
Interleukin-6 and other gp130-dependent cytokines selectively inhibit proliferation of macrophagelineage hemopoietic progenitor cells
-
Clutterbuck R, Powles R, Millar J, Catovsky D: Interleukin-6 and other gp130-dependent cytokines selectively inhibit proliferation of macrophagelineage hemopoietic progenitor cells. Exp Hematol 28: 1120-1128, 2000
-
(2000)
Exp Hematol
, vol.28
, pp. 1120-1128
-
-
Clutterbuck, R.1
Powles, R.2
Millar, J.3
Catovsky, D.4
-
26
-
-
4644249098
-
IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation
-
Park SJ, Nakagawa T, Kitamura H, Atsumi T, Kamon H, Sawa S, Kamimura D, Ueda N, Iwakura Y, Ishihara K,MurakamiM, Hirano T: IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation. J Immunol 173: 3844-3854, 2004
-
(2004)
J Immunol
, vol.173
, pp. 3844-3854
-
-
Park, S.J.1
Nakagawa, T.2
Kitamura, H.3
Atsumi, T.4
Kamon, H.5
Sawa, S.6
Kamimura, D.7
Ueda, N.8
Iwakura, Y.9
Ishihara, K.10
Murakami, M.11
Hirano, T.12
-
27
-
-
82955195759
-
New onset of uveitis during anti-tumor necrosis factor treatment for rheumatic diseases
-
Wendling D, Paccou J, Berthelot JM, Flipo RM, Guillaume-Czitrom S, Prati C, Dernis E, Direz G, Ferrazzi V, Ristori JM; CRI: New onset of uveitis during anti-tumor necrosis factor treatment for rheumatic diseases. Semin Arthritis Rheum 41: 503-510, 2011
-
(2011)
Semin Arthritis Rheum
, vol.41
, pp. 503-510
-
-
CRI1
Wendling, D.2
Paccou, J.3
Berthelot, J.M.4
Flipo, R.M.5
Guillaume-Czitrom, S.6
Prati, C.7
Dernis, E.8
Direz, G.9
Ferrazzi, V.10
Ristori, J.M.11
-
28
-
-
84857851446
-
Psoriasis onset with tocilizumab treatment for rheumatoid arthritis
-
Wendling D, Letho-Gyselinck H, Guillot X, Prati C: Psoriasis onset with tocilizumab treatment for rheumatoid arthritis. J Rheumatol 39: 657, 2012
-
(2012)
J Rheumatol
, vol.39
, pp. 657
-
-
Wendling, D.1
Letho-Gyselinck, H.2
Guillot, X.3
Prati, C.4
-
29
-
-
84879820208
-
Tocilizumabinduced immune complex glomerulonephritis in a patient with rheumatoid arthritis
-
Matsuo Y, Mizoguchi F, Kohsaka H, Ito E, Eishi Y, Miyasaka N: Tocilizumabinduced immune complex glomerulonephritis in a patient with rheumatoid arthritis. Rheumatology (Oxford) 52: 1341-1343, 2013
-
(2013)
Rheumatology (Oxford)
, vol.52
, pp. 1341-1343
-
-
Matsuo, Y.1
Mizoguchi, F.2
Kohsaka, H.3
Ito, E.4
Eishi, Y.5
Miyasaka, N.6
-
30
-
-
0027631201
-
Interleukin-6 receptor blockage ameliorates murine lupus nephritis
-
Kiberd BA: Interleukin-6 receptor blockage ameliorates murine lupus nephritis. J Am Soc Nephrol 4: 58-61, 1993
-
(1993)
J Am Soc Nephrol
, vol.4
, pp. 58-61
-
-
Kiberd, B.A.1
-
31
-
-
73649123508
-
Interleukin 6 (IL-6) deficiency delays lupus nephritis in MRL-Faslpr mice: The IL-6 pathway as a new therapeutic target in treatment of autoimmune kidney disease in systemic lupus erythematosus
-
Cash H, Relle M, Menke J, Brochhausen C, Jones SA, Topley N, Galle PR, Schwarting A: Interleukin 6 (IL-6) deficiency delays lupus nephritis in MRL-Faslpr mice: The IL-6 pathway as a new therapeutic target in treatment of autoimmune kidney disease in systemic lupus erythematosus. J Rheumatol 37: 60-70, 2010
-
(2010)
J Rheumatol
, vol.37
, pp. 60-70
-
-
Cash, H.1
Relle, M.2
Menke, J.3
Brochhausen, C.4
Jones, S.A.5
Topley, N.6
Galle, P.R.7
Schwarting, A.8
-
32
-
-
0028355713
-
Interleukin-6 exacerbates glomerulonephritis in (NZB x NZW)F1 mice
-
Ryffel B, Car BD, Gunn H, Roman D, Hiestand P, Mihatsch MJ: Interleukin-6 exacerbates glomerulonephritis in (NZB x NZW)F1 mice.AmJ Pathol 144: 927-937, 1994
-
(1994)
AmJ Pathol
, vol.144
, pp. 927-937
-
-
Ryffel, B.1
Car, B.D.2
Gunn, H.3
Roman, D.4
Hiestand, P.5
Mihatsch, M.J.6
-
33
-
-
0031861643
-
IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/WF1 mice
-
Mihara M, Takagi N, Takeda Y, Ohsugi Y: IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/WF1 mice. Clin Exp Immunol 112: 397-402, 1998
-
(1998)
Clin Exp Immunol
, vol.112
, pp. 397-402
-
-
Mihara, M.1
Takagi, N.2
Takeda, Y.3
Ohsugi, Y.4
-
34
-
-
33750011260
-
Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus
-
Liang B,Gardner DB,Griswold DE, Bugelski PJ, Song XY: Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus. Immunology 119: 296-305, 2006
-
(2006)
Immunology
, vol.119
, pp. 296-305
-
-
Liang, B.1
Gardner, D.B.2
Griswold, D.E.3
Bugelski, P.J.4
Song, X.Y.5
-
35
-
-
0030699416
-
Abrogation of glomerular injury in nephrotoxic nephritis by continuous infusion of interleukin-6
-
Karkar AM, Smith J, Tam FW, Pusey CD, Rees AJ: Abrogation of glomerular injury in nephrotoxic nephritis by continuous infusion of interleukin-6. Kidney Int 52: 1313-1320, 1997
-
(1997)
Kidney Int
, vol.52
, pp. 1313-1320
-
-
Karkar, A.M.1
Smith, J.2
Tam, F.W.3
Pusey, C.D.4
Rees, A.J.5
-
36
-
-
0027491179
-
Modulation of antibody-mediated glomerular injury in vivo by interleukin-6
-
Karkar AM, Tam FW, Proudfoot AE, Meager A, Rees AJ: Modulation of antibody-mediated glomerular injury in vivo by interleukin-6. Kidney Int 44: 967-973, 1993
-
(1993)
Kidney Int
, vol.44
, pp. 967-973
-
-
Karkar, A.M.1
Tam, F.W.2
Proudfoot, A.E.3
Meager, A.4
Rees, A.J.5
-
37
-
-
0030934956
-
Antibody independent crescentic glomerulonephritis inmuchaindeficient mice
-
Li S, Holdsworth SR, Tipping PG: Antibody independent crescentic glomerulonephritis inmuchaindeficient mice. Kidney Int 51:672-678, 1997
-
(1997)
Kidney Int
, vol.51
, pp. 672-678
-
-
Li, S.1
Holdsworth, S.R.2
Tipping, P.G.3
-
38
-
-
2642707490
-
Crescentic glomerulonephritis in CD4-and CD8-deficient mice. Requirement for CD4 but not CD8 cells
-
Tipping PG, Huang XR, Qi M, Van GY, Tang WW: Crescentic glomerulonephritis in CD4-and CD8-deficient mice. Requirement for CD4 but not CD8 cells. Am J Pathol 152: 1541-1548, 1998
-
(1998)
Am J Pathol
, vol.152
, pp. 1541-1548
-
-
Tipping, P.G.1
Huang, X.R.2
Qi, M.3
Van, G.Y.4
Tang, W.W.5
-
40
-
-
77955172196
-
The Th17 immune response in renal inflammation
-
Turner JE, Paust HJ, Steinmetz OM, Panzer U: The Th17 immune response in renal inflammation. Kidney Int 77: 1070-1075, 2010
-
(2010)
Kidney Int
, vol.77
, pp. 1070-1075
-
-
Turner, J.E.1
Paust, H.J.2
Steinmetz, O.M.3
Panzer, U.4
-
41
-
-
79952358774
-
The Th17-defining transcription factor RORgt promotes glomerulonephritis
-
Steinmetz OM, Summers SA, Gan PY, Semple T, Holdsworth SR, Kitching AR: The Th17-defining transcription factor RORgt promotes glomerulonephritis. J Am Soc Nephrol 22: 472-483, 2011
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 472-483
-
-
Steinmetz, O.M.1
Summers, S.A.2
Gan, P.Y.3
Semple, T.4
Holdsworth, S.R.5
Kitching, A.R.6
-
43
-
-
48049096638
-
IL-6/IL-6R axis plays a critical role in acute kidney injury
-
Nechemia-Arbely Y, Barkan D, Pizov G, Shriki A, Rose-John S, Galun E, Axelrod JH: IL-6/IL-6R axis plays a critical role in acute kidney injury. J Am Soc Nephrol 19: 1106-1115, 2008
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 1106-1115
-
-
Nechemia-Arbely, Y.1
Barkan, D.2
Pizov, G.3
Shriki, A.4
Rose-John, S.5
Galun, E.6
Axelrod, J.H.7
-
44
-
-
74049092328
-
Interleukin-6 release fromperipheralmononuclear cells is associated to disease activity and treatment response in patients with lupus nephritis
-
Esposito P, BallettaMM, Procino A, Postiglione L,Memoli B: Interleukin-6 release fromperipheralmononuclear cells is associated to disease activity and treatment response in patients with lupus nephritis. Lupus 18: 1329-1330, 2009
-
(2009)
Lupus
, vol.18
, pp. 1329-1330
-
-
Esposito, P.1
Balletta, M.M.2
Procino, A.3
Postiglione, L.4
Memoli, B.5
-
45
-
-
84983433658
-
Tocilizumab improves systemic rheumatoid vasculitis with necrotizing crescentic glomerulonephritis [published online ahead of print February 18, 2014]
-
Iijima T, Suwabe T, Sumida K, Hayami N, Hiramatsu R, Hasegawa E, Yamanouchi M, Hoshino J, Sawa N, Takaichi K, Oohashi K, Fujii T, Ubara Y: Tocilizumab improves systemic rheumatoid vasculitis with necrotizing crescentic glomerulonephritis [published online ahead of print February 18, 2014]. Mod Rheumatol doi:10.3109/ 14397595.2013.874748
-
Mod Rheumatol
-
-
Iijima, T.1
Suwabe, T.2
Sumida, K.3
Hayami, N.4
Hiramatsu, R.5
Hasegawa, E.6
Yamanouchi, M.7
Hoshino, J.8
Sawa, N.9
Takaichi, K.10
Oohashi, K.11
Fujii, T.12
Ubara, Y.13
-
46
-
-
80053159298
-
Complete remission of myeloperoxidase-anti-neutrophil cytoplasmic antibody-associated crescentic glomerulonephritis complicated with rheumatoid arthritis using a humanized anti-interleukin 6 receptor antibody
-
Sumida K, Ubara Y, Suwabe T, Hayami N, Hiramatsu R, Hasegawa E, Yamanouchi M, Hoshino J, Sawa N, Takemoto F, Takaichi K, Ohashi K: Complete remission of myeloperoxidase-anti-neutrophil cytoplasmic antibody-associated crescentic glomerulonephritis complicated with rheumatoid arthritis using a humanized anti-interleukin 6 receptor antibody. Rheumatology (Oxford) 50: 1928-1930, 2011
-
(2011)
Rheumatology (Oxford)
, vol.50
, pp. 1928-1930
-
-
Sumida, K.1
Ubara, Y.2
Suwabe, T.3
Hayami, N.4
Hiramatsu, R.5
Hasegawa, E.6
Yamanouchi, M.7
Hoshino, J.8
Sawa, N.9
Takemoto, F.10
Takaichi, K.11
Ohashi, K.12
-
47
-
-
75749113331
-
Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase i dosage-escalation study
-
Illei GG, Shirota Y, Yarboro CH, Daruwalla J, Tackey E, Takada K, Fleisher T, Balow JE, Lipsky PE: Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study. Arthritis Rheum 62: 542-552, 2010
-
(2010)
Arthritis Rheum
, vol.62
, pp. 542-552
-
-
Illei, G.G.1
Shirota, Y.2
Yarboro, C.H.3
Daruwalla, J.4
Tackey, E.5
Takada, K.6
Fleisher, T.7
Balow, J.E.8
Lipsky, P.E.9
-
48
-
-
0037015958
-
Characterization of anti-mouse interleukin-6 receptor antibody
-
Okazaki M, Yamada Y, Nishimoto N, Yoshizaki K, Mihara M: Characterization of anti-mouse interleukin-6 receptor antibody. Immunol Lett 84: 231-240, 2002
-
(2002)
Immunol Lett
, vol.84
, pp. 231-240
-
-
Okazaki, M.1
Yamada, Y.2
Nishimoto, N.3
Yoshizaki, K.4
Mihara, M.5
-
49
-
-
77953645116
-
Differences in wound healing in mice with deficiency of IL-6 versus IL-6 receptor
-
McFarland-ManciniMM, FunkHM, PaluchAM,ZhouM,Giridhar PV,Mercer CA, Kozma SC, Drew AF: Differences in wound healing in mice with deficiency of IL-6 versus IL-6 receptor. J Immunol 184: 7219-7228, 2010
-
(2010)
J Immunol
, vol.184
, pp. 7219-7228
-
-
McFarland-Mancini, M.M.1
Funk, H.M.2
Paluch, A.M.3
Zhou, M.4
Giridhar, P.V.5
Mercer, C.A.6
Kozma, S.C.7
Drew, A.F.8
-
50
-
-
79551668389
-
The emergence of TH17 cells as effectors of renal injury
-
Kitching AR, Holdsworth SR: The emergence of TH17 cells as effectors of renal injury. J Am Soc Nephrol 22: 235-238, 2011
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 235-238
-
-
Kitching, A.R.1
Holdsworth, S.R.2
-
51
-
-
70349448417
-
Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation
-
Marks BR,NowyhedHN,Choi JY, Poholek AC,Odegard JM, Flavell RA, Craft J: Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation. Nat Immunol 10: 1125-1132, 2009
-
(2009)
Nat Immunol
, vol.10
, pp. 1125-1132
-
-
Marks, B.R.1
Nowyhed, H.N.2
Choi, J.Y.3
Poholek, A.C.4
Odegard, J.M.5
Flavell, R.A.6
Craft, J.7
-
52
-
-
73349132687
-
Natural occurring IL-17 producing T cells regulate the initial phase of neutrophilmediated airway responses
-
Tanaka S, Yoshimoto T, Naka T, Nakae S, Iwakura Y, Cua D, Kubo M: Natural occurring IL-17 producing T cells regulate the initial phase of neutrophilmediated airway responses. J Immunol 183: 7523-7530, 2009
-
(2009)
J Immunol
, vol.183
, pp. 7523-7530
-
-
Tanaka, S.1
Yoshimoto, T.2
Naka, T.3
Nakae, S.4
Iwakura, Y.5
Cua, D.6
Kubo, M.7
-
53
-
-
34547514211
-
IL-6-dependent and-independent pathways in the development of interleukin 17-producing T helper cells
-
Kimura A, Naka T, Kishimoto T: IL-6-dependent and-independent pathways in the development of interleukin 17-producing T helper cells. Proc Natl Acad Sci U S A 104: 12099-12104, 2007
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12099-12104
-
-
Kimura, A.1
Naka, T.2
Kishimoto, T.3
-
54
-
-
84857411475
-
Hitting a complex target: An update on interleukin-6 trans-signalling
-
Waetzig GH, Rose-John S: Hitting a complex target: An update on interleukin-6 trans-signalling. Expert Opin Ther Targets 16: 225-236, 2012
-
(2012)
Expert Opin Ther Targets
, vol.16
, pp. 225-236
-
-
Waetzig, G.H.1
Rose-John, S.2
-
55
-
-
0030934551
-
Interleukin-6 expression after renal transplantation
-
Waiser J, Budde K, Katalinic A, Kuerzdörfer M, Riess R, Neumayer HH: Interleukin-6 expression after renal transplantation. Nephrol Dial Transplant 12: 753-759, 1997
-
(1997)
Nephrol Dial Transplant
, vol.12
, pp. 753-759
-
-
Waiser, J.1
Budde, K.2
Katalinic, A.3
Kuerzdörfer, M.4
Riess, R.5
Neumayer, H.H.6
-
56
-
-
0031025673
-
The signal transducer gp130 is shared by interleukin-6 family of haematopoietic and neurotrophic cytokines
-
Taga T: The signal transducer gp130 is shared by interleukin-6 family of haematopoietic and neurotrophic cytokines. AnnMed 29: 63-72, 1997
-
(1997)
AnnMed
, vol.29
, pp. 63-72
-
-
Taga, T.1
-
57
-
-
84883832799
-
A role of polymorphonuclear leukocytes and complement in nephrotoxic nephritis
-
Cochrane CG, Unanue ER, Dixon FJ: A role of polymorphonuclear leukocytes and complement in nephrotoxic nephritis. J Exp Med 122: 99-116, 1965
-
(1965)
J Exp Med
, vol.122
, pp. 99-116
-
-
Cochrane, C.G.1
Unanue, E.R.2
Dixon, F.J.3
-
58
-
-
80054728443
-
Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis
-
Anders HJ, Ryu M: Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis. Kidney Int 80: 915-925, 2011
-
(2011)
Kidney Int
, vol.80
, pp. 915-925
-
-
Anders, H.J.1
Ryu, M.2
-
59
-
-
84899124414
-
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
-
Mauer J, Chaurasia B, Goldau J, Vogt MC, Ruud J, Nguyen KD, Theurich S, Hausen AC, Schmitz J, Brönneke HS, Estevez E, Allen TL, Mesaros A, Partridge L, Febbraio MA, Chawla A, Wunderlich FT, Brüning JC: Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nat Immunol 15: 423-430, 2014
-
(2014)
Nat Immunol
, vol.15
, pp. 423-430
-
-
Mauer, J.1
Chaurasia, B.2
Goldau, J.3
Vogt, M.C.4
Ruud, J.5
Nguyen, K.D.6
Theurich, S.7
Hausen, A.C.8
Schmitz, J.9
Brönneke, H.S.10
Estevez, E.11
Allen, T.L.12
Mesaros, A.13
Partridge, L.14
Febbraio, M.A.15
Chawla, A.16
Wunderlich, F.T.17
Brüning, J.C.18
-
60
-
-
84906078630
-
Stat3 programs Th17-specific regulatory T cells to control GN
-
Kluger MA, Luig M, Wegscheid C, Goerke B, Paust HJ, Brix SR, Yan I, Mittrücker HW, Hagl B, Renner ED, Tiegs G, Wiech T, Stahl RA, Panzer U, Steinmetz OM: Stat3 programs Th17-specific regulatory T cells to control GN. J Am Soc Nephrol 25: 1291-1302, 2014
-
(2014)
J Am Soc Nephrol
, vol.25
, pp. 1291-1302
-
-
Kluger, M.A.1
Luig, M.2
Wegscheid, C.3
Goerke, B.4
Paust, H.J.5
Brix, S.R.6
Yan, I.7
Mittrücker, H.W.8
Hagl, B.9
Renner, E.D.10
Tiegs, G.11
Wiech, T.12
Stahl, R.A.13
Panzer, U.14
Steinmetz, O.M.15
-
61
-
-
84872182482
-
IL-6 controls the innate immune response against Listeria monocytogenes via classical IL-6 signaling
-
Hoge J, Yan I, Jänner N, Schumacher V, Chalaris A, Steinmetz OM, Engel DR, Scheller J, Rose-John S, Mittrücker HW: IL-6 controls the innate immune response against Listeria monocytogenes via classical IL-6 signaling. J Immunol 190: 703-711, 2013
-
(2013)
J Immunol
, vol.190
, pp. 703-711
-
-
Hoge, J.1
Yan, I.2
Jänner, N.3
Schumacher, V.4
Chalaris, A.5
Steinmetz, O.M.6
Engel, D.R.7
Scheller, J.8
Rose-John, S.9
Mittrücker, H.W.10
-
62
-
-
84877032979
-
Leukocyte-derived MMP9 is crucial for the recruitment of proinflammatory macrophages in experimental glomerulonephritis
-
Kluger MA, Zahner G, Paust HJ, Schaper M, Magnus T, Panzer U, Stahl RA: Leukocyte-derived MMP9 is crucial for the recruitment of proinflammatory macrophages in experimental glomerulonephritis. Kidney Int 83: 865-877, 2013
-
(2013)
Kidney Int
, vol.83
, pp. 865-877
-
-
Kluger, M.A.1
Zahner, G.2
Paust, H.J.3
Schaper, M.4
Magnus, T.5
Panzer, U.6
Stahl, R.A.7
|