Bacterial fitness shapes the population dynamics of antibiotic-resistant and -susceptible bacteria in a model of combined antibiotic and anti-virulence treatment

Journal of Theoretical Biology

Volumn 372, Issue , 2015, Pages 1-11

  Ternent, Lucy ^a,b   Dyson, Rosemary J ^a   Krachler, Anne Marie ^a   Jabbari, Sara ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Anti virulence drugs; Antibiotic resistance; Mathematical Modelling

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; ANTIVIRULENCE DRUG; MEROPENEM; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTICS; BACTERIUM; DRUG; NUMERICAL MODEL; POPULATION DYNAMICS; VIRULENCE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL FITNESS; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIAL LOAD; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIAL VIRULENCE; HOST PATHOGEN INTERACTION; HUMAN; IMMUNE RESPONSE; INFECTION PREVENTION; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; NONHUMAN; PHAGOCYTE; POPULATION DYNAMICS; PRIORITY JOURNAL; TREATMENT OUTCOME; BACTERIAL INFECTIONS; BACTERIUM; BIOLOGICAL MODEL; CROSS INFECTION; DRUG EFFECTS; VIRULENCE;

BACTERIA (MICROORGANISMS);

ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; HUMANS; MODELS, BIOLOGICAL; POPULATION DYNAMICS; VIRULENCE;

EID: 84924557053     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2015.02.011     Document Type: Article

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