Knockdown of CkrL by shRNA deteriorates hypoxia/reoxygenation-induced H9C2 cardiomyocyte apoptosis and survival inhibition Via Bax and downregulation of P-Erk1/2

Cell Biochemistry and Function

Volumn 33, Issue 2, 2015, Pages 80-88

  Zhang, Zhi Sheng ^a   Yang, Dong Yan ^a   Fu, Yan Bo ^a   Zhang, Lei ^a   Zhao, Qian Ping ^a   Li, Gang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Bax; Cell proliferation; Cell survival; CrkL (v crk avian sarcoma virus CT 10 oncogene homolog like); H9C2 cardiomyocyte line; Hypoxia reoxygenation; Phosphorylated extracellular signal regulated kinase1 2 (p ERK1 2)

Indexed keywords

CRK LIKE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; SHORT HAIRPIN RNA; CRK PROTEIN, HUMAN; ONCOPROTEIN; SMALL INTERFERING RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE EXACERBATION; DOWN REGULATION; GENE EXPRESSION; HEART MUSCLE CELL; HYPOXIA; LENTIVIRINAE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REOXYGENATION; ANIMAL; CELL HYPOXIA; GENE SILENCING; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS;

AVIAN SARCOMA VIRUS CT10; LENTIVIRUS; RATTUS;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL HYPOXIA; CELL SURVIVAL; DOWN-REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 3; MOLECULAR SEQUENCE DATA; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-CRK; RATS; RNA, SMALL INTERFERING;

EID: 84924520992     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.3093     Document Type: Article

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