Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 18, 2008, Pages 6638-6643

  Peng, Xu ^a   Wu, Xiaoyang ^a   Druso, Joseph E ^a   Wei, Huijun ^a,b   Park, Ann Yong Jin ^a,b   Kraus, Marc S ^a   Alcaraz, Ana ^a   Chen, Ju ^c   Chien, Shu ^c,d   Cerione, Richard A ^a   Guan, Jun Lin ^a,b  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Cardiac development; Signal transduction

Indexed keywords

FOCAL ADHESION KINASE; MYOCYTE ENHANCER FACTOR 2; MYOCYTE ENHANCER FACTOR 2A; MYOSIN LIGHT CHAIN 2; MYOSIN LIGHT CHAIN 2A; PHOSPHATIDYLINOSITOL 3 KINASE; CRE RECOMBINASE; INTEGRASE; MEF2A PROTEIN, MOUSE; MLC2A PROTEIN, MOUSE; MYOGENIC FACTOR; MYOSIN LIGHT CHAIN; PROTEIN KINASE P60;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; FEMALE; HEART DEVELOPMENT; HEART MUSCLE CELL; HEART RIGHT VENTRICLE HYPERTROPHY; HEART VENTRICLE SEPTUM DEFECT; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; ANTIBODY SPECIFICITY; CARDIOVASCULAR MALFORMATION; EMBRYO (ANATOMY); EMBRYO DEVELOPMENT; ENZYMOLOGY; GENE DELETION; HEART MUSCLE; METABOLISM; MOUSE MUTANT; PATHOLOGY; PRENATAL DEVELOPMENT; SURVIVAL; ULTRASTRUCTURE;

MUS;

ANIMALS; CARDIOVASCULAR ABNORMALITIES; CELL PROLIFERATION; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE DELETION; HYPERTROPHY, RIGHT VENTRICULAR; INTEGRASES; MICE; MICE, KNOCKOUT; MYOCARDIUM; MYOCYTES, CARDIAC; MYOGENIC REGULATORY FACTORS; MYOSIN LIGHT CHAINS; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS PP60(C-SRC); SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS;

EID: 44349136151     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802319105     Document Type: Article

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