'Neonatal' Nav1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour

Human Molecular Genetics

Volumn 24, Issue 5, 2015, Pages 1457-1468

  Gazina, Elena V ^a   Leaw, Bryan T W ^a   Richards, Kay L ^a   Wimmer, Verena C ^a   Kim, Tae H ^a   Aumann, Timothy D ^a   Featherby, Travis J ^a   Churilov, Leonid ^a   Hammond, Vicki E ^a   Reid, Christopher A ^a   Petrou, Steven ^a,b  

^a FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; SODIUM CHANNEL NAV1.2; ISOPROTEIN; PENTETRAZOLE; SCN2A1 PROTEIN, MOUSE;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR CHANGE; BRAIN DEVELOPMENT; CONTROLLED STUDY; GENE EXPRESSION; MOUSE; NERVE EXCITABILITY; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SEIZURE SUSCEPTIBILITY; ALTERNATIVE RNA SPLICING; ANIMAL; ANIMAL BEHAVIOR; BRAIN; C57BL MOUSE; CYTOLOGY; DISEASE MODEL; EXON; GENETIC PREDISPOSITION; GENETICS; MALE; METABOLISM; NERVE CELL; NEWBORN; PHENOTYPE; SEIZURE;

MUS;

ACTION POTENTIALS; ALTERNATIVE SPLICING; ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; BRAIN; DISEASE MODELS, ANIMAL; EXONS; GENETIC PREDISPOSITION TO DISEASE; MALE; MICE; MICE, INBRED C57BL; NAV1.2 VOLTAGE-GATED SODIUM CHANNEL; NEURONS; PENTYLENETETRAZOLE; PHENOTYPE; PROTEIN ISOFORMS; RNA, MESSENGER; SEIZURES;

EID: 84924514171     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddu562     Document Type: Article

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