메뉴 건너뛰기




Volumn 48, Issue 3, 2012, Pages 582-593

LRRK2 expression is enriched in the striosomal compartment of mouse striatum

Author keywords

Expression; Knockout; LRRK2; Striosome; Transgenic

Indexed keywords

ARGININE; BIOLOGICAL MARKER; GLYCINE; LEUCINE RICH REPEAT KINASE 2; PROTEIN MOR1; PROTEIN RASGRP1; UNCLASSIFIED DRUG;

EID: 84865560576     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.07.017     Document Type: Article
Times cited : (54)

References (51)
  • 1
    • 70349991886 scopus 로고    scopus 로고
    • LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
    • Alegre-Abarrategui J., et al. LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model. Hum. Mol. Genet. 2009, 18:4022-4034.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 4022-4034
    • Alegre-Abarrategui, J.1
  • 2
    • 0022930826 scopus 로고
    • Parallel organization of functionally segregated circuits linking basal ganglia and cortex
    • Alexander G.E., et al. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu. Rev. Neurosci. 1986, 9:357-381.
    • (1986) Annu. Rev. Neurosci. , vol.9 , pp. 357-381
    • Alexander, G.E.1
  • 3
    • 33845298032 scopus 로고    scopus 로고
    • Localization of LRRK2 to membranous and vesicular structures in mammalian brain
    • Biskup S., et al. Localization of LRRK2 to membranous and vesicular structures in mammalian brain. Ann. Neurol. 2006, 60:557-569.
    • (2006) Ann. Neurol. , vol.60 , pp. 557-569
    • Biskup, S.1
  • 4
    • 78649389313 scopus 로고    scopus 로고
    • The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
    • Cookson M.R. The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease. Nat. Rev. Neurosci. 2010, 11:791-797.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 791-797
    • Cookson, M.R.1
  • 5
    • 84859152259 scopus 로고    scopus 로고
    • Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments
    • Crittenden J.R., Graybiel A.M. Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartments. Front. Neuroanat. 2011, 5:59.
    • (2011) Front. Neuroanat. , vol.5 , pp. 59
    • Crittenden, J.R.1    Graybiel, A.M.2
  • 6
    • 62449156198 scopus 로고    scopus 로고
    • Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy
    • Crittenden J.R., et al. Dysregulation of CalDAG-GEFI and CalDAG-GEFII predicts the severity of motor side-effects induced by anti-parkinsonian therapy. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:2892-2896.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 2892-2896
    • Crittenden, J.R.1
  • 7
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: mechanisms and models
    • Dauer W., Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 8
    • 0023238549 scopus 로고
    • Pattern formation in the striatum: developmental changes in the distribution of striatonigral neurons
    • Fishell G., van der Kooy D. Pattern formation in the striatum: developmental changes in the distribution of striatonigral neurons. J. Neurosci. 1987, 7:1969-1978.
    • (1987) J. Neurosci. , vol.7 , pp. 1969-1978
    • Fishell, G.1    van der Kooy, D.2
  • 9
    • 79951480697 scopus 로고    scopus 로고
    • Exclusive and common targets of neostriatofugal projections of rat striosome neurons: a single neuron-tracing study using a viral vector
    • Fujiyama F., et al. Exclusive and common targets of neostriatofugal projections of rat striosome neurons: a single neuron-tracing study using a viral vector. Eur. J. Neurosci. 2011, 33:668-677.
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 668-677
    • Fujiyama, F.1
  • 10
    • 33645790701 scopus 로고    scopus 로고
    • LRRK2 expression linked to dopamine-innervated areas
    • Galter D., et al. LRRK2 expression linked to dopamine-innervated areas. Ann. Neurol. 2006, 59:714-719.
    • (2006) Ann. Neurol. , vol.59 , pp. 714-719
    • Galter, D.1
  • 11
    • 0021860893 scopus 로고
    • The neostriatal mosaic. I. Compartmental organization of projections from the striatum to the substantia nigra in the rat
    • Gerfen C.R. The neostriatal mosaic. I. Compartmental organization of projections from the striatum to the substantia nigra in the rat. J. Comp. Neurol. 1985, 236:454-476.
    • (1985) J. Comp. Neurol. , vol.236 , pp. 454-476
    • Gerfen, C.R.1
  • 12
    • 0026611391 scopus 로고
    • The neostriatal mosaic: multiple levels of compartmental organization
    • Gerfen C.R. The neostriatal mosaic: multiple levels of compartmental organization. J. Neural Transm. Suppl. 1992, 36:43-59.
    • (1992) J. Neural Transm. Suppl. , vol.36 , pp. 43-59
    • Gerfen, C.R.1
  • 13
    • 79959869606 scopus 로고    scopus 로고
    • Modulation of striatal projection systems by dopamine
    • Gerfen C.R., Surmeier D.J. Modulation of striatal projection systems by dopamine. Annu. Rev. Neurosci. 2011, 34:441-466.
    • (2011) Annu. Rev. Neurosci. , vol.34 , pp. 441-466
    • Gerfen, C.R.1    Surmeier, D.J.2
  • 14
    • 0021678534 scopus 로고
    • Correspondence between the dopamine islands and striosomes of the mammalian striatum
    • Graybiel A.M. Correspondence between the dopamine islands and striosomes of the mammalian striatum. Neuroscience 1984, 13:1157-1187.
    • (1984) Neuroscience , vol.13 , pp. 1157-1187
    • Graybiel, A.M.1
  • 15
    • 0025293685 scopus 로고
    • Neurotransmitters and neuromodulators in the basal ganglia
    • Graybiel A.M. Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci. 1990, 13:244-254.
    • (1990) Trends Neurosci. , vol.13 , pp. 244-254
    • Graybiel, A.M.1
  • 16
    • 48249091260 scopus 로고    scopus 로고
    • Habits, rituals, and the evaluative brain
    • Graybiel A.M. Habits, rituals, and the evaluative brain. Annu. Rev. Neurosci. 2008, 31:359-387.
    • (2008) Annu. Rev. Neurosci. , vol.31 , pp. 359-387
    • Graybiel, A.M.1
  • 17
    • 0011798071 scopus 로고
    • Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining
    • Graybiel A.M., Ragsdale C.W. Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining. Proc. Natl. Acad. Sci. U. S. A. 1978, 75:5723-5726.
    • (1978) Proc. Natl. Acad. Sci. U. S. A. , vol.75 , pp. 5723-5726
    • Graybiel, A.M.1    Ragsdale, C.W.2
  • 18
    • 77953395313 scopus 로고    scopus 로고
    • Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions
    • Greggio E., Cookson M.R. Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions. ASN Neuro 2009, 1.
    • (2009) ASN Neuro , vol.1
    • Greggio, E.1    Cookson, M.R.2
  • 19
    • 33746267531 scopus 로고    scopus 로고
    • Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
    • Greggio E., et al. Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiol. Dis. 2006, 23:329-341.
    • (2006) Neurobiol. Dis. , vol.23 , pp. 329-341
    • Greggio, E.1
  • 20
    • 48749095219 scopus 로고    scopus 로고
    • Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra
    • Han B.S., et al. Expression of the LRRK2 gene in the midbrain dopaminergic neurons of the substantia nigra. Neurosci. Lett. 2008, 442:190-194.
    • (2008) Neurosci. Lett. , vol.442 , pp. 190-194
    • Han, B.S.1
  • 21
    • 33845796537 scopus 로고    scopus 로고
    • Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain
    • Higashi S., et al. Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain. J. Neurochem. 2007, 100:368-381.
    • (2007) J. Neurochem. , vol.100 , pp. 368-381
    • Higashi, S.1
  • 22
    • 84861552733 scopus 로고    scopus 로고
    • LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors
    • Hinkle K.M., et al. LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors. Mol. Neurodegener. 2012, 7:25.
    • (2012) Mol. Neurodegener. , vol.7 , pp. 25
    • Hinkle, K.M.1
  • 23
    • 0020955120 scopus 로고
    • Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation
    • Huttner W.B., et al. Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J. Cell Biol. 1983, 96:1374-1388.
    • (1983) J. Cell Biol. , vol.96 , pp. 1374-1388
    • Huttner, W.B.1
  • 24
    • 34447118788 scopus 로고    scopus 로고
    • LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity
    • Jaleel M., et al. LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity. Biochem. J. 2007, 405:307-317.
    • (2007) Biochem. J. , vol.405 , pp. 307-317
    • Jaleel, M.1
  • 25
    • 0024367497 scopus 로고
    • Compartmental origins of striatal efferent projections in the cat
    • Jimenez-Castellanos J., Graybiel A.M. Compartmental origins of striatal efferent projections in the cat. Neuroscience 1989, 32:297-321.
    • (1989) Neuroscience , vol.32 , pp. 297-321
    • Jimenez-Castellanos, J.1    Graybiel, A.M.2
  • 26
    • 23844446427 scopus 로고    scopus 로고
    • The striatofugal fiber system in primates: a reevaluation of its organization based on single-axon tracing studies
    • Levesque M., Parent A. The striatofugal fiber system in primates: a reevaluation of its organization based on single-axon tracing studies. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:11888-11893.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 11888-11893
    • Levesque, M.1    Parent, A.2
  • 27
    • 67649813448 scopus 로고    scopus 로고
    • Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease
    • Li Y., et al. Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease. Nat. Neurosci. 2009, 12:826-828.
    • (2009) Nat. Neurosci. , vol.12 , pp. 826-828
    • Li, Y.1
  • 28
    • 33751256567 scopus 로고    scopus 로고
    • The familial Parkinsonism gene LRRK2 regulates neurite process morphology
    • MacLeod D., et al. The familial Parkinsonism gene LRRK2 regulates neurite process morphology. Neuron 2006, 52:587-593.
    • (2006) Neuron , vol.52 , pp. 587-593
    • MacLeod, D.1
  • 29
    • 34250624810 scopus 로고    scopus 로고
    • A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases
    • Mandemakers W., et al. A cell biological perspective on mitochondrial dysfunction in Parkinson disease and other neurodegenerative diseases. J. Cell Sci. 2007, 120:1707-1716.
    • (2007) J. Cell Sci. , vol.120 , pp. 1707-1716
    • Mandemakers, W.1
  • 30
    • 33646146878 scopus 로고    scopus 로고
    • Anatomical localization of leucine-rich repeat kinase 2 in mouse brain
    • Melrose H., et al. Anatomical localization of leucine-rich repeat kinase 2 in mouse brain. Neuroscience 2006, 139:791-794.
    • (2006) Neuroscience , vol.139 , pp. 791-794
    • Melrose, H.1
  • 31
    • 34547107314 scopus 로고    scopus 로고
    • A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease
    • Melrose H.L., et al. A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease. Neuroscience 2007, 147:1047-1058.
    • (2007) Neuroscience , vol.147 , pp. 1047-1058
    • Melrose, H.L.1
  • 32
    • 84856632181 scopus 로고    scopus 로고
    • LRRK2 inhibition attenuates microglial inflammatory responses
    • Moehle M.S., et al. LRRK2 inhibition attenuates microglial inflammatory responses. J. Neurosci. 2012, 32:1602-1611.
    • (2012) J. Neurosci. , vol.32 , pp. 1602-1611
    • Moehle, M.S.1
  • 33
    • 0026587806 scopus 로고
    • Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Moratalla R., et al. Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:3859-3863.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 3859-3863
    • Moratalla, R.1
  • 34
    • 77956674229 scopus 로고    scopus 로고
    • 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
    • Nichols R.J., et al. 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization. Biochem. J. 2010, 430:393-404.
    • (2010) Biochem. J. , vol.430 , pp. 393-404
    • Nichols, R.J.1
  • 36
    • 79951534656 scopus 로고    scopus 로고
    • LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool
    • Piccoli G., et al. LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J. Neurosci. 2011, 31:2225-2237.
    • (2011) J. Neurosci. , vol.31 , pp. 2225-2237
    • Piccoli, G.1
  • 37
    • 0034469820 scopus 로고    scopus 로고
    • Dopaminergic innervation of human basal ganglia
    • Prensa L., et al. Dopaminergic innervation of human basal ganglia. J. Chem. Neuroanat. 2000, 20:207-213.
    • (2000) J. Chem. Neuroanat. , vol.20 , pp. 207-213
    • Prensa, L.1
  • 38
    • 33947663512 scopus 로고    scopus 로고
    • LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins
    • Sakaguchi-Nakashima A., et al. LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins. Curr. Biol. 2007, 17:592-598.
    • (2007) Curr. Biol. , vol.17 , pp. 592-598
    • Sakaguchi-Nakashima, A.1
  • 39
    • 79960661378 scopus 로고    scopus 로고
    • LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: a morphological and quantitative study
    • Sharma S., et al. LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: a morphological and quantitative study. Neuropathol. Appl. Neurobiol. 2011, 37:777-790.
    • (2011) Neuropathol. Appl. Neurobiol. , vol.37 , pp. 777-790
    • Sharma, S.1
  • 40
    • 46549089664 scopus 로고    scopus 로고
    • LRRK2 regulates synaptic vesicle endocytosis
    • Shin N., et al. LRRK2 regulates synaptic vesicle endocytosis. Exp. Cell Res. 2008, 314:2055-2065.
    • (2008) Exp. Cell Res. , vol.314 , pp. 2055-2065
    • Shin, N.1
  • 41
    • 79751509762 scopus 로고    scopus 로고
    • Parkinson's disease: genetics and pathogenesis
    • Shulman J.M., et al. Parkinson's disease: genetics and pathogenesis. Annu. Rev. Pathol. 2011, 6:193-222.
    • (2011) Annu. Rev. Pathol. , vol.6 , pp. 193-222
    • Shulman, J.M.1
  • 42
    • 33644934224 scopus 로고    scopus 로고
    • LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain
    • Simon-Sanchez J., et al. LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain. Eur. J. Neurosci. 2006, 23:659-666.
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 659-666
    • Simon-Sanchez, J.1
  • 43
    • 72549103697 scopus 로고    scopus 로고
    • Dopamine and synaptic plasticity in dorsal striatal circuits controlling action selection
    • Surmeier D.J., et al. Dopamine and synaptic plasticity in dorsal striatal circuits controlling action selection. Curr. Opin. Neurobiol. 2009, 19:621-628.
    • (2009) Curr. Opin. Neurobiol. , vol.19 , pp. 621-628
    • Surmeier, D.J.1
  • 44
    • 33745917404 scopus 로고    scopus 로고
    • Distribution of PINK1 and LRRK2 in rat and mouse brain
    • Taymans J.M., et al. Distribution of PINK1 and LRRK2 in rat and mouse brain. J. Neurochem. 2006, 98:951-961.
    • (2006) J. Neurochem. , vol.98 , pp. 951-961
    • Taymans, J.M.1
  • 45
    • 9644289706 scopus 로고    scopus 로고
    • Functional diversity and specificity of neostriatal interneurons
    • Tepper J.M., Bolam J.P. Functional diversity and specificity of neostriatal interneurons. Curr. Opin. Neurobiol. 2004, 14:685-692.
    • (2004) Curr. Opin. Neurobiol. , vol.14 , pp. 685-692
    • Tepper, J.M.1    Bolam, J.P.2
  • 46
    • 84863821582 scopus 로고    scopus 로고
    • Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons
    • Threlfell S., et al. Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons. Neuron 2012, 75:58-64.
    • (2012) Neuron , vol.75 , pp. 58-64
    • Threlfell, S.1
  • 47
    • 0037174773 scopus 로고    scopus 로고
    • Efferent projections from the striatal patch compartment: anterograde degeneration after selective ablation of neurons expressing mu-opioid receptor in rats
    • Tokuno H., et al. Efferent projections from the striatal patch compartment: anterograde degeneration after selective ablation of neurons expressing mu-opioid receptor in rats. Neurosci. Lett. 2002, 332:5-8.
    • (2002) Neurosci. Lett. , vol.332 , pp. 5-8
    • Tokuno, H.1
  • 48
    • 84861936797 scopus 로고    scopus 로고
    • Whole-brain mapping of direct inputs to midbrain dopamine neurons
    • Watabe-Uchida M., et al. Whole-brain mapping of direct inputs to midbrain dopamine neurons. Neuron 2012, 74:858-873.
    • (2012) Neuron , vol.74 , pp. 858-873
    • Watabe-Uchida, M.1
  • 49
    • 28044460070 scopus 로고    scopus 로고
    • Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
    • West A.B., et al. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:16842-16847.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 16842-16847
    • West, A.B.1
  • 50
    • 40949145205 scopus 로고    scopus 로고
    • Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: implications for Parkinson's disease
    • Westerlund M., et al. Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: implications for Parkinson's disease. Neuroscience 2008, 152:429-436.
    • (2008) Neuroscience , vol.152 , pp. 429-436
    • Westerlund, M.1
  • 51
    • 56249144183 scopus 로고    scopus 로고
    • Lrrk2 and alpha-synuclein are co-regulated in rodent striatum
    • Westerlund M., et al. Lrrk2 and alpha-synuclein are co-regulated in rodent striatum. Mol. Cell. Neurosci. 2008, 39:586-591.
    • (2008) Mol. Cell. Neurosci. , vol.39 , pp. 586-591
    • Westerlund, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.