Effects in cigarette smoke stimulated bronchial epithelial cells of a corticosteroid entrapped into nanostructured lipid carriers

Journal of Nanobiotechnology

Volumn 12, Issue 1, 2014, Pages

  Bondì, Maria Luisa ^a   Ferraro, Maria ^b   Di Vincenzo, Serena ^b   Gerbino, Stefania ^b   Cavallaro, Gennara ^c   Giammona, Gaetano ^c   Botto, Chiara ^c   Gjomarkaj, Mark ^b   Pace, Elisabetta ^b  

^a CNR   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF PALERMO   (Italy)

Author keywords

Airway epithelial cell; Asthma; Chronic obstructive pulmonary disease; Cigarette smoke; Corticosteroid; Fluticasone propionate; Nanostructured lipid carriers

Indexed keywords

BIOCOMPATIBILITY; CELL CULTURE; CELL DEATH; CYTOLOGY; DRUG DELIVERY; MEDICAL NANOTECHNOLOGY; MOBILE SECURITY; PULMONARY DISEASES; SMOKE; TOBACCO; VOLATILE FATTY ACIDS;

AIRWAY EPITHELIAL CELLS; ASTHMA; CHRONIC OBSTRUCTIVE PULMONARY DISEASE; CIGARETTE SMOKES; CORTICOSTEROID; FLUTICASONE PROPIONATE; NANOSTRUCTURED LIPID CARRIERS;

CELLS;

CIGARETTE SMOKE; FLUTICASONE PROPIONATE; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 4; DRUG CARRIER; FLUTICASONE; LIPID; NANOMATERIAL; TLR4 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BIOCOMPATIBILITY; BRONCHUS MUCOSA; CELL DEATH; CELL PROTECTION; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; CYTOTOXICITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; NANOMEDICINE; OXIDATIVE STRESS; SCANNING ELECTRON MICROSCOPY; ADVERSE EFFECTS; BRONCHUS; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; METABOLISM; SMOKING;

APOPTOSIS; BRONCHI; CELLS, CULTURED; DRUG CARRIERS; EPITHELIAL CELLS; FLUTICASONE; GLUTATHIONE; HUMANS; LIPIDS; NANOSTRUCTURES; REACTIVE OXYGEN SPECIES; SMOKING; TOLL-LIKE RECEPTOR 4;

EID: 84924426000     PISSN: None     EISSN: 14773155     Source Type: Journal    
DOI: 10.1186/s12951-014-0046-4     Document Type: Article

References (43)

1. Chaturvedi NP, Solanki H: Pulmonary drug delivery system: review. Nit J Appl Pharm 2013, 5:7-10.
2. Torchilin VP: Nanocarriers. Pharm Res 2007, 24:2333-2334.
3. Terzano C, Allegra L, Alhaique F, Marianecci C, Carafa M: Non-phospholipid vesicles for pulmonary glucocorticoid delivery. Eur J Pharm Biopharm 2005, 59:57-62.
4. Buxton DB: Nanomedicine for the management of lung and blood diseases. Nanomedicine (Lond) 2009, 4:331-339.
5. Nassimi M, Schleh C, Lauenstein HD, Hussein R, Hoymann HG, Koch W, Pohlmann G, Krug N, Sewald K, Rittinghausen S, Braun A, Müller-Goymannet C: A toxicological evaluation of inhaled solid lipid nanoparticles used as a potential drug delivery system for the lung. Eur J Pharm Biopharm 2010, 75:107-116.
6. Doktorovová S, Araújo J, Garcia ML, Rakovský E, Souto EB: Formulating fluticasone propionate in novel PEG-containing nanostructured lipid carriers (PEG-NLC). Colloids Surf B Biointerfaces 2010, 75:538-542.
7. Üner M, Yener G: Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives. Int J Nanomedicine 2007, 2:289-300.
8. Bondì ML, Craparo EF, Giammona G, Cervello M, Azzolina A, Diana P, Martorana A, Cirrincione G: Nanostructured lipid carriers-containing anticancer compounds: preparation, characterization, and cytotoxicity studies. Drug Deliv 2007, 14:61-67.
9. Bondì ML, Azzolina A, Craparo EF, Capuano G, Lampiasi N, Giammona G, Cervello M: Solid lipid nanoparticles (SLNs) containing nimesulide: preparation, characterization and in cytotoxicity studies. Curr Nanosci 2009, 5:39-44.
10. Bondì ML, Craparo EF, Picone P, Di Carlo M, Di Gesù R, Capuano G, Giammona G: Curcumin entrapped into lipid nanosystems inhibits neuroblastoma cancer cell growth and activate Hsp70 protein. Curr Nanosci 2010, 6:439-445.
11. Alonso MJ: Nanomedicine for overcoming biological barriers. Biomed Pharmacother 2004, 58:168-172.
12. Tobío M, Gref R, Sánchez A, Langer R, Alonso MJ: Stealth PLA-PEG nanoparticles as protein carriers for nasal administration. Pharm Res 1998, 15:270-275.
13. Vila A, Sánchez A, Tobío M, Calvo P, Alonso MJ: Design of biodegradable particles for protein delivery. J Control Release 2002, 78:15-24.
14. Craparo EF, Teresi G, Bondì ML, Licciardi M, Cavallaro G: Phospholipid-polyaspartamide micelles for pulmonary delivery of corticosteroids. Int J Pharm 2011, 406:135-144.
15. Pitarresi G, Casadei MA, Mandracchia D, Paolicelli P, Palumbo FS, Giammona G: Photocrosslinking of dextran and polyaspartamide derivatives: a combination suitable for colon-specific drug delivery. J Control Release 2007, 119:328-338.
16. Marianecci C, Paolino D, Celia C, Fresta M, Carafa M, Alhaique F: Non-ionic surfactant vesicles in pulmonary glucocorticoid delivery: characterization and interaction with human lung fibroblast. J Control Release 2010, 147:127-135.
17. Pace E, Ferraro M, Di Vincenzo S, Cipollina C, Gerbino S, Cigna D, Caputo V, Balsamo R, Lanata L, Gjomarkaj M: Comparative cytoprotective effects of carbocysteine and fluticasone propionate in cigarette smoke extract-stimulated bronchial epithelial cells. Cell Stress Chaperones 2013, 18:733-743.
18. Faux SP, Tai T, Thorne D, Xu Y, Breheny D, Gaca M: The role of oxidative stress in the biological responses of lung epithelial cells to cigarette smoke. Biomarkers 2009, 14:90-96.
19. Biswas SK, Rahman I: Environmental toxicity, redox signaling and lung inflammation: the role of glutathione. Mol Aspects Med 2009, 30:60-76.
20. Ghezzi P: Role of glutathione in immunity and inflammation in the lung. Int J Gen Med 2011, 4:105-113.
21. Pace E, Ferraro M, Siena L, Melis M, Montalbano A, Johnson M, Bonsignore MR, Bonsignore G, Gjomarkaj M: Cigarette smoke increases TLR4 and modifies LPS mediated responses in airway epithelial cells. Immunology 2008, 124:401-411.
22. Pace E, Ferraro M, Uasuf CG, Giarratano A, La Grutta S, Liotta G, Johnson M, Gjomarkaj M: Cilomilast counteracts the effects of cigarette smoke in airway epithelial cells. Cell Immunol 2011, 268:47-53.
23. Olsson B, Bondesson E, Borgström L, Edsbäcker S, Eirefelt S, Ekelund K, Gustavsson L, Hegelund-Myrbäck T: Pulmonary Drug Metabolism, Clearance, and Absorption. In Controlled Pulmonary Drug Delivery. Edited by Smith HDC, Hickey AJ. Germany: Springer; 2011:21-50.
24. Brusselle GG, Joos GF, Bracke KR: New insights into the immunology of chronic obstructive pulmonary disease. Lancet 2011, 378:1015-1026.
25. Kelsen SG, Duan X, Ji R, Perez O, Liu C, Merali S: Cigarette smoke induces an unfolded protein response in the human lung: a proteomic approach. Am J Respir Cell Mol Biol 2008, 38:541-550.
26. Smola M, Vandamme T, Sokolowski A: Nanocarriers as pulmonary drug delivery systems to treat and to diagnose respiratory and non respiratory diseases. Int J Nanomedicine 2008, 3:1-19.
27. Rouse JJ, Whateley TL, Thomas M, Eccleston GM: Controlled drug delivery to the lung: influence of hyaluronic acid solution conformation on its adsorption to hydrophobic drug particles. Int J Pharm 2007, 330:175-182.
28. Jaspart S, Bertholet P, Piel G, Dogné JM, Delattre L, Evrard B: Solid lipid microparticles as a sustained release system for pulmonary drug delivery. Eur J Pharm Biopharm 2007, 5:47-56.
29. Bondì ML, Montana G, Craparo EF, Di Gesù R, Giammona G, Bonura A, Colombo P: Lipid nanoparticles as delivery vehicles for the Parietaria judaica major allergen Par j 2. Int J Nanomedicine 2011, 6:2953-2962.
30. Liu X, Conner H, Kobayashi T, Kim H, Wen F, Abe S, Fang Q, Wang X, Hashimoto M, Bitterman P, Rennardt SI: Cigarette smoke extract induces DNA damage but not apoptosis in human bronchial epithelial cells. Am J Respir Cell Mol Biol 2005, 33:121-129.
31. Moretto N, Facchinetti F, Southworth T, Civelli M, Singh D: Patacchini R: α, β-Unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases. Am J Physiol Lung Cell Mol Physiol 2009, 296:839-848.
32. Su Y, Han W, Giraldo C, De Li Y, Block ER: Effect of cigarette smoke extract on nitric oxide synthase in pulmonary artery endothelial cells. Am J Respir Cell Mol Biol 1998, 19:819-825.
33. MacNee W: Oxidants/antioxidants and COPD. Chest 2000, 117:303-317.
34. Baglole CJ, Bushinsky SM, Garcia TM, Kode A, Rahman I, Sime PJ, Phipps RP: Differential induction of apoptosis by cigarette smoke extract in primary human lung fibroblast strains: implications for emphysema. Am J Physiol Lung Cell Mol Physiol 2006, 291:19-29.
35. Rahman I, MacNee W: Oxidative stress and regulation of glutathione in lung inflammation. Eur Respir J 2000, 16:534-544.
36. Barnes PJ: Theophylline for COPD. Thorax 2006, 61:742-744.
37. Luppi F, Aarbiou J, van Wetering S, Rahman I, de Boer WI, Rabe KF, Hiemstra PS: Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione. Respir Res 2005, 6:140-151.
38. Van der Toorn M, Smit-de Vries MP, Slebos DJ, de Bruin HG, Abello N, Van Oosterhout AJ, Bischoff R, Kauffman HF: Cigarette smoke irreversibly modifies glutathione in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol 2007, 293:1156-1162.
39. Chen L, Wang T, Zhang JY, Zhang SF, Liu DS, Xu D, Wang X, Chen YJ, Wen FQ: Toll-like receptor 4 relates to lipopolysaccharide-induced mucus hypersecretion in rat airway. Arch Med Res 2009, 40:10-17.
40. Pace E, Ferraro M, Minervini MI, Vitulo P, Pipitone L, Chiappara G, Siena L, Montalbano AM, Johnson M, Gjomarkaj M: Beta defensin-2 is reduced in central but not in distal airways of smoker COPD patients. PLoS One 2012, 7:e33601.
41. Geraghty P, Dabo AJ, D'Armiento J: TLR4 protein contributes to cigarette smoke-induced matrix metalloproteinase-1 (MMP-1) expression in chronic obstructive pulmonary disease. J Biol Chem 2011, 286:30211-30218.
42. Mortaz E, Henricks PA, Kraneveld AD, Givi ME, Garssen J, Folkerts G: Cigarette smoke induces the release of CXCL-8 from human bronchial epithelial cells via TLRs and induction of the inflammasome. Biochim Biophys Acta 1812, 2011:1104-1110.
43. Rahman I, Kode A, Biswas SK: Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nat Protoc 2006, 1:3159-3165.