Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: Role of glutathione

Respiratory Research

Volumn 6, Issue , 2005, Pages

  Luppi, Fabrizio ^a   Aarbiou, Jamil ^a   van Wetering, Sandra ^a   Rahman, Irfan ^b   de Boer, Willem I ^a   Rabe, Klaus F ^a   Hiemstra, Pieter S ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CIGARETTE SMOKE; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; TAR; TOBACCO TAR;

ARTICLE; BRONCHUS MUCOSA; CELL CULTURE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CYTOTOXICITY; ENZYME ACTIVATION; EPITHELIUM CELL; IMMUNOBLOTTING; IN VITRO STUDY; LUNG CANCER; MOLECULAR MECHANICS; PROTEIN LOCALIZATION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING; WOUND HEALING; BRONCHUS; DOSE RESPONSE; DRUG EFFECTS; HUMAN; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

BRONCHI; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GLUTATHIONE; HUMANS; MAP KINASE SIGNALING SYSTEM; REACTIVE OXYGEN SPECIES; TARS; WOUND HEALING;

EID: 28344453450     PISSN: 1465993X     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-6-140     Document Type: Article

References (48)

1. Church DF, Pryor WA: Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect 1985, 64:111-126.
2. Lannan S, Donaldson K, Brown D, MacNee W: Effect of cigarette smoke and its condensates on alveolar epithelial cell injury in vitro. Am J Physiol 1994, 266(1 Pt 1):L92-100.
3. MacNee W, Rahman I: Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease? Trends Mol Med 2001, 7(2):55-62.
4. Rennard SI: Inflammation and repair processes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999, 160(5 Pt 2):S12-16.
5. Jeffery PK: Remodeling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med 2001, 164(10 Pt 2):S28-38.
6. Saetta M, Turato G, Baraldo S, Zanin A, Braccioni F, Mapp CE, Maestrelli P, Cavallesco G, Papi A, Fabbri LM: Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation. Am J Respir Crit Care Med 2000, 161(3 Pt 1):1016-1021.
7. Trevisani L, Sartori S, Bovolenta MR, Mazzoni M, Pazzi P, Putinati S, Potena A: Structural characterization of the bronchial epithelium of subjects with chronic bronchitis and in asymptomatic smokers. Respiration 1992, 59(3):136-144.
8. Demoly P, Simony-Lafontaine J, Chanez P, Pujol JL, Lequeux N, Michel FB, Bousquet J: Cell proliferation in the bronchial mucosa of asthmatics and chronic bronchitics. Am J Respir Crit Care Med 1994, 150(1):214-217.
9. Lee JJ, Liu D, Lee JS, Kurie JM, Khuri FR, Ibarguen H, Morice RC, Walsh G, Ro JY, Broxson A et al: Long-term impact of smoking on lung epithelial proliferation in current and former smokers. J Natl Cancer Inst 2001, 93(14):1081-1088.
10. Rahman I, MacNee W: Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease. Am J Physiol 1999, 277(6 Pt 1):L1067-1088.
11. Kurie JM, Shin HJ, Lee JS, Morice RC, Ro JY, Lippman SM, Hittelman WN, Yu R, Lee JJ, Hong WK: Increased epidermal growth factor receptor expression in metaplastic bronchial epithelium. Clin Cancer Res 1996, 2(10):1787-1793.
12. Vignola AM, Chanez P, Chiappara G, Merendino A, Pace E, Rizzo A, la Rocca AM, Bellia V, Bonsignore G, Bousquet J: Transforming growth factor-beta expression in mucosal biopsies in asthma and chronic bronchitis. Am J Respir Crit Care Med 1997, 156(2 Pt 1):591-599.
13. Chang L, Karin M: Mammalian MAP kinase signalling cascades. Nature 2001, 410(6824):37-40.
14. Takeyama K, Jung B, Shim JJ, Burgel PR, Dao-Pick T, Ueki IF, Protin U, Kroschel P, Nadel JA: Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke. Am J Physiol Lung Cell Mol Physiol 2001, 280(1):L165-172.
15. Kim HJ, Liu X, Wang H, Kohyama T, Kobayashi T, Wen FQ, Romberger DJ, Abe S, MacNee W, Rahman I et al: Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke. Am J Physiol Lung Cell Mol Physiol 2002, 283(2):L409-417.
16. van Wetering S, van der Linden AC, van Sterkenburg MA, de Boer WI, Kuijpers AL, Schalkwijk J, Hiemstra PS: Regulation of SLPI and elafin release from bronchial epithelial cells by neutrophil defensins. Am J Physiol Lung Cell Mol Physiol 2000, 278(1):L51-58.
17. Aarbiou J, Ertmann M, van Wetering S, van Noort P, Rook D, Rabe KF, Litvinov SV, van Krieken JH, de Boer WI, Hiemstra PS: Human neutrophil defensins induce lung epithelial cell proliferation in vitro. J Leukoc Biol 2002, 72(1):167-174.
18. Aarbiou J, Verhoosel RM, Van Wetering S, De Boer WI, Van Krieken JH, Litvinov SV, Rabe KF, Hiemstra PS: Neutrophil defensins enhance lung epithelial wound closure and mucin gene expression in vitro. Am J Respir Cell Mol Biol 2004, 30(2):193-201.
19. Rahman I, Li XY, Donaldson K, Harrison DJ, MacNee W: Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivo under oxidative stress. Am J Physiol 1995, 269(3 Pt 1):L285-292.
20. Tietze F: Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 1969, 27(3):502-522.
21. Cantral DE, Sisson JH, Veys T, Rennard SI, Spurzem JR: Effects of cigarette smoke extract on bovine bronchial epithelial cell attachment and migration. Am J Physiol 1995, 268(5 Pt 1):L723-728.
22. Wang H, Liu X, Umino T, Skold CM, Zhu Y, Kohyama T, Spurzem JR, Romberger DJ, Rennard SI: Cigarette smoke inhibits human bronchial epithelial cell repair processes. Am J Respir Cell Mol Biol 2001, 25(6):772-779.
23. Sekhon HS, Wright JL, Churg A: Cigarette smoke causes rapid cell proliferation in small airways and associated pulmonary arteries. Am J Physiol 1994, 267(5 Pt 1):L557-563.
24. Ohguro N, Fukuda M, Sasabe T, Tano Y: Concentration dependent effects of hydrogen peroxide on lens epithelial cells. Br J Ophthalmol 1999, 83(9):1064-1068.
25. Dal-Pizzol F, Klamt F, Dalmolin RJ, Bernard EA, Moreira JC: Mitogenic signaling mediated by oxidants in retinol treated Sertoli cells. Free Radic Res 2001, 35(6):749-755.
26. Gotoh Y, Noda T, Iwakiri R, Fujimoto K, Rhoads CA, Aw TY: Lipid peroxide-induced redox imbalance differentially mediates CaCo-2 cell proliferation and growth arrest. Cell Prolif 2002, 35(4):221-235.
27. Hoshino Y, Mio T, Nagai S, Miki H, Ito I, Izumi T: Cytotoxic effects of cigarette smoke extract on an alveolar type II cell-derived cell line. Am J Physiol Lung Cell Mol Physiol 2001, 281(2):L509-516.
28. Rahman I, Mulier B, Gilmour PS, Watchorn T, Donaldson K, Jeffery PK, MacNee W: Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB. Biochem Pharmacol 2001, 62(6):787-794.
29. Mulier B, Rahman I, Watchorn T, Donaldson K, MacNee W, Jeffery PK: Hydrogen peroxide-induced epithelial injury: the protective role of intracellular nonprotein thiols (NPSH). Eur Respir J 1998, 11(2):384-391.
30. de Boer WI, van Schadewijk A, Sont JK, Sharma HS, Stolk J, Hiemstra PS, van Krieken JH: Transforming growth factor beta1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998, 158(6):1951-1957.
31. Jardine H, MacNee W, Donaldson K, Rahman I: Molecular mechanism of transforming growth factor (TGF)-beta1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1. J Biol Chem 2002, 277(24):21158-21166.
32. Reddy S, Finkelstein EI, Wong PS, Phung A, Cross CE, van der Vliet A: Identification of glutathione modifications by cigarette smoke. Free Radic Biol Med 2002, 33(11):1490-1498.
33. Fan H, Derynck R: Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades. Embo J 1999, 18(24):6962-6972.
34. Lemjabbar H, Li D, Gallup M, Sidhu S, Drori E, Basbaum C: Tobacco smoke-induced lung cell proliferation mediated by tumor necrosis factor alpha-converting enzyme and amphiregulin. J Biol Chem 2003, 278(28):26202-26207.
35. Shao MX, Nakanaga T, Nadel JA: Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells. Am J Physiol Lung Cell Mol Physiol 2004, 287(2):L420-427.
36. Papi A, Casoni G, Caramori G, Guzzinati I, Boschetto P, Ravenna F, Calia N, Petruzzelli S, Corbetta L, Cavallesco G et al: COPD increases the risk of squamous histological subtype in smokers who develop non-small cell lung carcinoma. Thorax 2004, 59(8):679-681.
37. Skillrud DM, Offord KP, Miller RD: Higher risk of lung cancer in chronic obstructive pulmonary disease. A prospective, matched, controlled study. Ann Intern Med 1986, 105(4):503-507.
38. Richter A, O'Donnell RA, Powell RM, Sanders MW, Holgate ST, Djukanovic R, Davies DE: Autocrine ligands for the epidermal growth factor receptor mediate interleukin-8 release from bronchial epithelial cells in response to cigarette smoke. Am J Respir Cell Mol Biol 2002, 27(1):85-90.
39. West KA, Brognard J, Clark AS, Linnoila IR, Yang X, Swain SM, Harris C, Belinsky S, Dennis PA: Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. J Clin Invest 2003, 111(1):81-90.
40. Cattaneo MG, Codignola A, Vicentini LM, Clementi F, Sher E: Nicotine stimulates a serotonergic autocrine loop in human small-cell lung carcinoma. Cancer Res 1993, 53(22):5566-5568.
41. Wickenden JA, Clarke MC, Rossi AG, Rahman I, Faux SP, Donaldson K, MacNee W: Cigarette smoke prevents apoptosis through inhibition of caspase activation and induces necrosis. Am J Respir Cell Mol Biol 2003, 29(5):562-570.
42. Dypbukt JM, Ankarcrona M, Burkitt M, Sjoholm A, Strom K, Orrenius S, Nicotera P: Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines. J Biol Chem 1994, 269(48):30553-30560.
43. Moreno-Manzano V, Ishikawa Y, Lucio-Cazana J, Kitamura M: Suppression of apoptosis by all-trans-retinoic acid. Dual intervention in the c-Jun n-terminal kinase-AP-1 pathway. J Biol Chem 1999, 274(29):20251-20258.
44. Makin G, Dive C: Apoptosis and cancer chemotherapy. Trends Cell Biol 2001, 11(11):S22-26.
45. Rennard SI: Cigarette smoke in research. Am J Respir Cell Mol Biol 2004, 31(5):479-480.
46. Trichopoulos D, Mollo F, Tomatis L, Agapitos E, Delsedime L, Zavitsanos X, Kalandidi A, Katsouyanni K, Riboli E, Saracci R: Active and passive smoking and pathological indicators of lung cancer risk in an autopsy study. Jama 1992, 268(13):1697-1701.
47. Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF, Ahn NG: Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 1994, 265(5174):966-970.
48. Brognard J, Dennis PA: Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants. Cell Death Differ 2002, 9(9):893-904.