Evolutionary Signatures amongst Disease Genes Permit Novel Methods for Gene Prioritization and Construction of Informative Gene-Based Networks

PLoS Genetics

Volumn 11, Issue 2, 2015, Pages 1-17

  Priedigkeit, Nolan ^a   Wolfe, Nicholas ^a   Clark, Nathan L ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1BETA; PROTEIN MCL 1; MCL1 PROTEIN, HUMAN;

ANXA9 GENE; ARNT GENE; ARTICLE; CERS2 GENE; CHROMOSOME 1; CONTROLLED STUDY; CTSK GENE; CTSS GENE; DEVELOPMENTAL DISORDER; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENSA GENE; EVOLUTIONARY RATE COVARIATION; GENE; GENE TARGETING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC PARAMETERS; GOLPH3L GENE; HIRSCHSPRUNG DISEASE; HORMAD1 GENE; HUMAN; MCL1 GENE; MELANOMA; MOLECULAR EVOLUTION; MOLECULAR GENETICS; NEOPLASM; NONHUMAN; SETDB1 GENE; BIOLOGY; CHROMOSOME; GENE REGULATORY NETWORK; GENETICS; HUMAN GENOME; PATHOLOGY; PROTEIN TERTIARY STRUCTURE;

CHROMOSOMES; COMPUTATIONAL BIOLOGY; EVOLUTION, MOLECULAR; GENE REGULATORY NETWORKS; GENOME, HUMAN; HIRSCHSPRUNG DISEASE; HUMANS; MELANOMA; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PROTEIN STRUCTURE, TERTIARY;

EID: 84924423448     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004967     Document Type: Article

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