메뉴 건너뛰기




Volumn 8, Issue 2, 2015, Pages 237-246

Individualizing prophylaxis in hemophilia: A review

Author keywords

arthropathy; hemarthroses; hemophilia; personalized medicine; pharmacokinetics; prophylaxis

Indexed keywords

ADOLESCENT DISEASE; ARTHROPATHY; BLEEDING TENDENCY; CHEMOPROPHYLAXIS; CHILDHOOD DISEASE; CLINICAL EVALUATION; CLINICAL STUDY; DISEASE COURSE; HEMARTHROSIS; HEMOPHILIA; HUMAN; JOINT FUNCTION; NONHUMAN; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PATIENT COMPLIANCE; PERSONALIZED MEDICINE; PHARMACODYNAMICS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; HEMOPHILIA A;

EID: 84924419773     PISSN: 17474086     EISSN: 17474094     Source Type: Journal    
DOI: 10.1586/17474086.2015.1002465     Document Type: Review
Times cited : (53)

References (65)
  • 2
    • 34547757915 scopus 로고    scopus 로고
    • Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia
    • Manco-Johnson MJ, Abshire TC, Shapiro AD, et al. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia. N Engl J Med 2007;357:535-44
    • (2007) N Engl J Med , vol.357 , pp. 535-544
    • Manco-Johnson, M.J.1    Abshire, T.C.2    Shapiro, A.D.3
  • 3
    • 0002099315 scopus 로고
    • Haemophilia in Sweden. VII. Incidence, treatment and prophylaxis of arthropathy and other musculo-skeletal manifestations of haemophilia A and B
    • Ahlberg A. Haemophilia in Sweden. VII. Incidence, treatment and prophylaxis of arthropathy and other musculo-skeletal manifestations of haemophilia A and B. Acta Orthop Scand Suppl 1965;(suppl 77): 3-132
    • (1965) Acta Orthop Scand Suppl , pp. 3-132
    • Ahlberg, A.1
  • 4
    • 0026635406 scopus 로고
    • Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B
    • Nilsson IM, Berntorp E, Lofqvist T, et al. Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B. J Intern Med 1992;232:25-32
    • (1992) J Intern Med , vol.232 , pp. 25-32
    • Nilsson, I.M.1    Berntorp, E.2    Lofqvist, T.3
  • 5
    • 33646759553 scopus 로고    scopus 로고
    • Tailored prophylaxis in severe hemophilia A: Interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study
    • Feldman BM, Pai M, Rivard GE, et al. Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study. J Thromb Haemost 2006;4:1228-36
    • (2006) J Thromb Haemost , vol.4 , pp. 1228-1236
    • Feldman, B.M.1    Pai, M.2    Rivard, G.E.3
  • 6
    • 77954827460 scopus 로고    scopus 로고
    • The path to personalized medicine
    • Hamburg MA, Collins FS. The path to personalized medicine. N Engl J Med 2010;363:301-4
    • (2010) N Engl J Med , vol.363 , pp. 301-304
    • Hamburg, M.A.1    Collins, F.S.2
  • 7
    • 80155150460 scopus 로고    scopus 로고
    • Quantifying factors for the success of stratified medicine
    • Trusheim MR, Burgess B, Hu SX, et al. Quantifying factors for the success of stratified medicine. Nat Rev Drug Discov 2011;10:817-33
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 817-833
    • Trusheim, M.R.1    Burgess, B.2    Hu, S.X.3
  • 8
    • 0033028402 scopus 로고    scopus 로고
    • Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized
    • Astermark J, Petrini P, Tengborn L, et al. Primary prophylaxis in severe haemophilia should be started at an early age but can be individualized. Br J Haematol 1999;105: 1109-13
    • (1999) Br J Haematol , vol.105 , pp. 1109-1113
    • Astermark, J.1    Petrini, P.2    Tengborn, L.3
  • 9
    • 0034746292 scopus 로고    scopus 로고
    • What factors should influence the dosage and interval of prophylactic treatment in patients with severe haemophilia A and B
    • Petrini P. What factors should influence the dosage and interval of prophylactic treatment in patients with severe haemophilia A and B? Haemophilia 2001;7: 99-102
    • (2001) Haemophilia , vol.7 , pp. 99-102
    • Petrini, P.1
  • 10
    • 84862862541 scopus 로고    scopus 로고
    • Developing models of haemophilia care
    • Street A. Developing models of haemophilia care. Haemophilia 2012;18(Suppl 4):89-93
    • (2012) Haemophilia , vol.18 , pp. 89-93
    • Street, A.1
  • 11
    • 77952712296 scopus 로고    scopus 로고
    • Comparative pharmacokinetics of plasma-and albumin-free recombinant factor VIII in children and adults: The influence of blood sampling schedule on observed age-related differences and implications for dose tailoring
    • Björkman S, Blanchette VS, Fischer K, et al. Comparative pharmacokinetics of plasma-and albumin-free recombinant factor VIII in children and adults: The influence of blood sampling schedule on observed age-related differences and implications for dose tailoring. J Thromb Haemost 2010;8:730-6
    • (2010) J Thromb Haemost , vol.8 , pp. 730-736
    • Björkman, S.1    Blanchette, V.S.2    Fischer, K.3
  • 12
    • 59849093369 scopus 로고    scopus 로고
    • Break-through bleeding in relation to predicted factor VIII levels in patients receiving prophylactic treatment for severe hemophilia A
    • Collins PW, Blanchette VS, Fischer K, et al. Break-through bleeding in relation to predicted factor VIII levels in patients receiving prophylactic treatment for severe hemophilia A. J Thromb Haemost 2009;7: 413-20
    • (2009) J Thromb Haemost , vol.7 , pp. 413-420
    • Collins, P.W.1    Blanchette, V.S.2    Fischer, K.3
  • 13
    • 33645973263 scopus 로고    scopus 로고
    • Practice patterns in haemophilia A therapy-global progress towards optimal care
    • Geraghty S, Dunkley T, Harrington C, et al. Practice patterns in haemophilia A therapy-global progress towards optimal care. Haemophilia 2006;12:75-81
    • (2006) Haemophilia , vol.12 , pp. 75-81
    • Geraghty, S.1    Dunkley, T.2    Harrington, C.3
  • 14
    • 84857116684 scopus 로고    scopus 로고
    • The influence of prophylactic factor VIII in severe haemophilia A
    • Gissel M, Whelihan MF, Ferris LA, et al. The influence of prophylactic factor VIII in severe haemophilia A. Haemophilia 2011;18:193-9
    • (2011) Haemophilia , vol.18 , pp. 193-199
    • Gissel, M.1    Whelihan, M.F.2    Ferris, L.A.3
  • 15
    • 73249136485 scopus 로고    scopus 로고
    • Controversies regarding the prophylactic management of adults with severe haemophilia A
    • quiz 9-22
    • Valentino LA. Controversies regarding the prophylactic management of adults with severe haemophilia A. Haemophilia 2009;15:5-18, quiz 9-22
    • (2009) Haemophilia , vol.15 , pp. 5-18
    • Valentino, L.A.1
  • 16
    • 0028004222 scopus 로고
    • A longitudinal study of orthopaedic outcomes for severe factor-VIII-deficient haemophiliacs. The Orthopaedic Outcome Study Group
    • Aledort LM, Haschmeyer RH, Pettersson H. A longitudinal study of orthopaedic outcomes for severe factor-VIII-deficient haemophiliacs. The Orthopaedic Outcome Study Group. J Intern Med 1994;236:391-9
    • (1994) J Intern Med , vol.236 , pp. 391-399
    • Aledort, L.M.1    Haschmeyer, R.H.2    Pettersson, H.3
  • 17
    • 0036827020 scopus 로고    scopus 로고
    • Prophylactic treatment for severe haemophilia: Comparison of an intermediate-dose to a high-dose regimen
    • Fischer K, Astermark J, van der Bom JG, et al. Prophylactic treatment for severe haemophilia: comparison of an intermediate-dose to a high-dose regimen. Haemophilia 2002;8:753-60
    • (2002) Haemophilia , vol.8 , pp. 753-760
    • Fischer, K.1    Astermark, J.2    Van Der Bom, J.G.3
  • 18
    • 0036489639 scopus 로고    scopus 로고
    • Modified magnetic resonance imaging score compared with orthopaedic and radiological scores for the evaluation of haemophilic arthropathy
    • Funk MB, Schmidt H, Becker S, et al. Modified magnetic resonance imaging score compared with orthopaedic and radiological scores for the evaluation of haemophilic arthropathy. Haemophilia 2002;8:98-103
    • (2002) Haemophilia , vol.8 , pp. 98-103
    • Funk, M.B.1    Schmidt, H.2    Becker, S.3
  • 19
    • 79951923137 scopus 로고    scopus 로고
    • Biotribological and biomechanical changes after experimental haemarthrosis in the rabbit knee
    • Ravanbod R, Torkaman G, Esteki A. Biotribological and biomechanical changes after experimental haemarthrosis in the rabbit knee. Haemophilia 2011;17:124-33
    • (2011) Haemophilia , vol.17 , pp. 124-133
    • Ravanbod, R.1    Torkaman, G.2    Esteki, A.3
  • 20
    • 2342538377 scopus 로고    scopus 로고
    • Experimental haemophilic synovitis: Rationale and development of a murine model of human factor VIII deficiency
    • Valentino LA, Hakobyan N, Kazarian T, et al. Experimental haemophilic synovitis: rationale and development of a murine model of human factor VIII deficiency. Haemophilia 2004;10:280-7
    • (2004) Haemophilia , vol.10 , pp. 280-287
    • Valentino, L.A.1    Hakobyan, N.2    Kazarian, T.3
  • 21
    • 63049109313 scopus 로고    scopus 로고
    • Prevention of haemarthrosis in a murine model of acute joint bleeding
    • Valentino LA, Hakobyan N, Kazarian T, et al. Prevention of haemarthrosis in a murine model of acute joint bleeding. Haemophilia 2008;15:314-19
    • (2008) Haemophilia , vol.15 , pp. 314-319
    • Valentino, L.A.1    Hakobyan, N.2    Kazarian, T.3
  • 22
    • 75649099044 scopus 로고    scopus 로고
    • Lessons from animal models of arthritis over the past decade
    • van den Berg WB. Lessons from animal models of arthritis over the past decade. Arthritis Res Ther 2009;11:250
    • (2009) Arthritis Res Ther , vol.11 , pp. 250
    • Van Den Berg, W.B.1
  • 23
  • 25
    • 43749088065 scopus 로고    scopus 로고
    • Experimental haemophilic arthropathy in a mouse model of a massive haemarthrosis: Gross, radiological and histological changes
    • Hakobyan N, Enockson C, Cole AA, et al. Experimental haemophilic arthropathy in a mouse model of a massive haemarthrosis: gross, radiological and histological changes. Haemophilia 2008;14:804-9
    • (2008) Haemophilia , vol.14 , pp. 804-809
    • Hakobyan, N.1    Enockson, C.2    Cole, A.A.3
  • 26
    • 79952177822 scopus 로고    scopus 로고
    • Neoangiogenesis contributes to the development of hemophilic synovitis
    • Acharya SS, Kaplan RNM, Macdonald D, et al. Neoangiogenesis contributes to the development of hemophilic synovitis. Blood 2011;117:2484-93
    • (2011) Blood , vol.117 , pp. 2484-2493
    • Acharya, S.S.1    Kaplan, R.N.M.2    Macdonald, D.3
  • 27
    • 58249104986 scopus 로고    scopus 로고
    • The combination of the biomarkers urinary C-terminal telopeptide of type II collagen, serum cartilage oligomeric matrix protein, and serum chondroitin sulfate 846 reflects cartilage damage in hemophilic arthropathy
    • Jansen NW, Roosendaal G, Lundin B, et al. The combination of the biomarkers urinary C-terminal telopeptide of type II collagen, serum cartilage oligomeric matrix protein, and serum chondroitin sulfate 846 reflects cartilage damage in hemophilic arthropathy. Arthritis Rheum 2009;60:290-8
    • (2009) Arthritis Rheum , vol.60 , pp. 290-298
    • Jansen, N.W.1    Roosendaal, G.2    Lundin, B.3
  • 28
    • 84904719468 scopus 로고    scopus 로고
    • The burden of bleeding in haemophilia: Is one bleed too many
    • Gringeri A, Ewenstein B, Reininger A. The burden of bleeding in haemophilia: is one bleed too many? Haemophilia 2014;20: 459-63
    • (2014) Haemophilia , vol.20 , pp. 459-463
    • Gringeri, A.1    Ewenstein, B.2    Reininger, A.3
  • 29
    • 84865560607 scopus 로고    scopus 로고
    • Haemophilia care in Europe: The ESCHQoL study
    • Schramm W, Gringeri A, Ljung R, et al. Haemophilia care in Europe: The ESCHQoL study. Haemophilia 2012;18: 729-37
    • (2012) Haemophilia , vol.18 , pp. 729-737
    • Schramm, W.1    Gringeri, A.2    Ljung, R.3
  • 30
    • 84871073400 scopus 로고    scopus 로고
    • Magnetic resonance imaging and joint outcomes in boys with severe hemophilia A treated with tailored primary prophylaxis in Canada
    • Kraft J, Blanchette V, Babyn P, et al. Magnetic resonance imaging and joint outcomes in boys with severe hemophilia A treated with tailored primary prophylaxis in Canada. J Thromb Haemost 2012;10: 2494-502
    • (2012) J Thromb Haemost , vol.10 , pp. 2494-2502
    • Kraft, J.1    Blanchette, V.2    Babyn, P.3
  • 31
    • 84857951468 scopus 로고    scopus 로고
    • Clinical severity of haemophilia A: Does the classification of the 1950s still stand
    • Den Uijl IE, Mauser Bunschoten EP, Roosendaal G, et al. Clinical severity of haemophilia A: does the classification of the 1950s still stand? Haemophilia 2011;17: 849-53
    • (2011) Haemophilia , vol.17 , pp. 849-853
    • Den Uijl, I.E.1    Mauser Bunschoten, E.P.2    Roosendaal, G.3
  • 32
    • 84898433309 scopus 로고    scopus 로고
    • Advancing personalized care in hemophilia A: Ten years' experience with an advanced category antihemophilic factor prepared using a plasma/albumin-free method
    • Berntorp E, Spotts G, Patrone L, et al. Advancing personalized care in hemophilia A: Ten years' experience with an advanced category antihemophilic factor prepared using a plasma/albumin-free method. Biologics 2014;8:115-27
    • (2014) Biologics , vol.8 , pp. 115-127
    • Berntorp, E.1    Spotts, G.2    Patrone, L.3
  • 33
    • 11144330901 scopus 로고    scopus 로고
    • A 6-year follow-up of dosing, coagulation factor levels and bleedings in relation to joint status in the prophylactic treatment of haemophilia
    • Ahnstrom J, Berntorp E, Lindvall K, et al. A 6-year follow-up of dosing, coagulation factor levels and bleedings in relation to joint status in the prophylactic treatment of haemophilia. Haemophilia 2004;10:689-97
    • (2004) Haemophilia , vol.10 , pp. 689-697
    • Ahnstrom, J.1    Berntorp, E.2    Lindvall, K.3
  • 34
    • 4944263724 scopus 로고    scopus 로고
    • Clinical evaluation of an advanced category antihaemophilic factor prepared using a plasma/albumin-free method: Pharmacokinetics, efficacy, and safety in previously treated patients with haemophilia A
    • Tarantino MD, Collins PW, Hay CR, et al. Clinical evaluation of an advanced category antihaemophilic factor prepared using a plasma/albumin-free method: pharmacokinetics, efficacy, and safety in previously treated patients with haemophilia A. Haemophilia 2004;10:428-37
    • (2004) Haemophilia , vol.10 , pp. 428-437
    • Tarantino, M.D.1    Collins, P.W.2    Hay, C.R.3
  • 35
    • 84888412772 scopus 로고    scopus 로고
    • Development of novel treatment options for patients with haemophilia
    • Ehrlich HJ, Wong WY, Ewenstein BM, et al. Development of novel treatment options for patients with haemophilia. Hamostaseologie 2013;33(Suppl 1):S36-8
    • (2013) Hamostaseologie , vol.33 , pp. S36-S38
    • Ehrlich, H.J.1    Wong, W.Y.2    Ewenstein, B.M.3
  • 36
    • 84859197329 scopus 로고    scopus 로고
    • Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients
    • Powell JS, Josephson NC, Quon D, et al. Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients. Blood 2012;119: 3031-7
    • (2012) Blood , vol.119 , pp. 3031-3037
    • Powell, J.S.1    Josephson, N.C.2    Quon, D.3
  • 37
    • 84894408816 scopus 로고    scopus 로고
    • An open-label phase i study to evaluate the pharmacokinetics and safety profile of BAY 94-9027, a PEGylated B-domain-deleted recombinant factor VIII, in previously treated patients with severe hemophilia A
    • July 8-12, Paris, France
    • Coyle TE, Reding M, Lin JC, et al. An open-label phase I study to evaluate the pharmacokinetics and safety profile of BAY 94-9027, a PEGylated B-domain-deleted recombinant factor VIII, in previously treated patients with severe hemophilia A. Presented at: World Federation of Hemophilia World Congress; July 8-12, Paris, France; 2012
    • (2012) Presented At: World Federation of Hemophilia World Congress
    • Coyle, T.E.1    Reding, M.2    Lin, J.C.3
  • 38
    • 84876182114 scopus 로고    scopus 로고
    • Enhancing the pharmacokinetic properties of recombinant factor VIII: First-in-man trial of glycoPEGylated recombinant factor VIII in patients with hemophilia A
    • Tiede A, Brand B, Fischer R, et al. Enhancing the pharmacokinetic properties of recombinant factor VIII: first-in-man trial of glycoPEGylated recombinant factor VIII in patients with hemophilia A. J Thromb Haemost 2013;11:670-8
    • (2013) J Thromb Haemost , vol.11 , pp. 670-678
    • Tiede, A.1    Brand, B.2    Fischer, R.3
  • 39
    • 80052669248 scopus 로고    scopus 로고
    • Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: A first human dose trial in patients with hemophilia B
    • Negrier C, Knobe K, Tiede A, et al. Enhanced pharmacokinetic properties of a glycoPEGylated recombinant factor IX: A first human dose trial in patients with hemophilia B. Blood 2011;118:2695-701
    • (2011) Blood , vol.118 , pp. 2695-2701
    • Negrier, C.1    Knobe, K.2    Tiede, A.3
  • 40
    • 84889769562 scopus 로고    scopus 로고
    • Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B
    • Powell JS, Pasi KJ, Ragni MV, et al. Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B. N Engl J Med 2013;369:2313-23
    • (2013) N Engl J Med , vol.369 , pp. 2313-2323
    • Powell, J.S.1    Pasi, K.J.2    Ragni, M.V.3
  • 41
    • 84874109190 scopus 로고    scopus 로고
    • Progression of haemophilic arthropathy in children: A Lithuanian-Danish comparative study
    • Saulyte Trakymiene S, Clausen N, Poulsen LH, et al. Progression of haemophilic arthropathy in children: A Lithuanian-Danish comparative study. Haemophilia 2012;19:212-18
    • (2012) Haemophilia , vol.19 , pp. 212-218
    • Saulyte Trakymiene, S.1    Clausen, N.2    Poulsen, L.H.3
  • 42
    • 79953306825 scopus 로고    scopus 로고
    • A randomized clinical trial of prophylaxis in children with hemophilia A (the ESPRIT Study)
    • Gringeri A, Lundin B, Mackensen SV, et al. A randomized clinical trial of prophylaxis in children with hemophilia A (the ESPRIT Study). J Thromb Haemost 2011;9:700-10
    • (2011) J Thromb Haemost , vol.9 , pp. 700-710
    • Gringeri, A.1    Lundin, B.2    Mackensen, S.V.3
  • 43
    • 84877926861 scopus 로고    scopus 로고
    • Prophylaxis and quality of life in patients with hemophilia A during routine treatment with ADVATE [antihemophilic factor (recombinant), plasma/albumin-free method] in Germany: A subgroup analysis of the ADVATE PASS post-approval, non-interventional study
    • Pollmann H, Klamroth R, Vidovic N, et al. Prophylaxis and quality of life in patients with hemophilia A during routine treatment with ADVATE [antihemophilic factor (recombinant), plasma/albumin-free method] in Germany: A subgroup analysis of the ADVATE PASS post-approval, non-interventional study. Ann Hematol 2013;92:689-98
    • (2013) Ann Hematol , vol.92 , pp. 689-698
    • Pollmann, H.1    Klamroth, R.2    Vidovic, N.3
  • 44
    • 80053190308 scopus 로고    scopus 로고
    • Survey of current prophylaxis practices and bleeding characteristics of children with severe haemophilia A in US haemophilia treatment centres
    • Ragni MV, Fogarty PJ, Josephson NC, et al. Survey of current prophylaxis practices and bleeding characteristics of children with severe haemophilia A in US haemophilia treatment centres. Haemophilia 2012;18: 63-8
    • (2012) Haemophilia , vol.18 , pp. 63-68
    • Ragni, M.V.1    Fogarty, P.J.2    Josephson, N.C.3
  • 45
    • 51249108178 scopus 로고    scopus 로고
    • The use of prophylaxis in 2663 children and adults with haemophilia: Results of the 2006 Canadian national haemophilia prophylaxis survey
    • Biss TT, Chan AK, Blanchette VS, et al. The use of prophylaxis in 2663 children and adults with haemophilia: results of the 2006 Canadian national haemophilia prophylaxis survey. Haemophilia 2008;14: 923-30
    • (2008) Haemophilia , vol.14 , pp. 923-930
    • Biss, T.T.1    Chan, A.K.2    Blanchette, V.S.3
  • 46
    • 84874967483 scopus 로고    scopus 로고
    • Musculoskeletal health of subjects with hemophilia A treated with tailored prophylaxis: Canadian Hemophilia Primary Prophylaxis (CHPS) Study
    • Hilliard P, Zourikian N, Blanchette V, et al. Musculoskeletal health of subjects with hemophilia A treated with tailored prophylaxis: Canadian Hemophilia Primary Prophylaxis (CHPS) Study. J Thromb Haemost 2013;11:460-6
    • (2013) J Thromb Haemost , vol.11 , pp. 460-466
    • Hilliard, P.1    Zourikian, N.2    Blanchette, V.3
  • 47
    • 79951898096 scopus 로고    scopus 로고
    • Low dose secondary prophylaxis reduces joint bleeding in severe and moderate haemophilic children: A pilot study in China
    • Wu R, Luke KH, Poon MC, et al. Low dose secondary prophylaxis reduces joint bleeding in severe and moderate haemophilic children: A pilot study in China. Haemophilia 2011;17:70-4
    • (2011) Haemophilia , vol.17 , pp. 70-74
    • Wu, R.1    Luke, K.H.2    Poon, M.C.3
  • 48
    • 84863192453 scopus 로고    scopus 로고
    • A comparison of traditional vs. Canadian tailored prophylaxis dosing of prophylactic factor infusions in children with haemophilia A and B in a single hemophilia treatment center
    • Dodd C, Watts RG. A comparison of traditional vs. Canadian tailored prophylaxis dosing of prophylactic factor infusions in children with haemophilia A and B in a single hemophilia treatment center. Haemophilia 2012;18:561-7
    • (2012) Haemophilia , vol.18 , pp. 561-567
    • Dodd, C.1    Watts, R.G.2
  • 50
    • 84865558828 scopus 로고    scopus 로고
    • Treatment patterns, health-related quality of life and adherence to prophylaxis among haemophilia A patients in the United States
    • Duncan N, Shapiro A, Ye X, et al. Treatment patterns, health-related quality of life and adherence to prophylaxis among haemophilia A patients in the United States. Haemophilia 2012;18:760-5
    • (2012) Haemophilia , vol.18 , pp. 760-765
    • Duncan, N.1    Shapiro, A.2    Ye, X.3
  • 51
    • 51249087295 scopus 로고    scopus 로고
    • A survey of adherence to haemophilia therapy in six European countries: Results and recommendations
    • De Moerloose P, Urbancik W, Van Den Berg HM, et al. A survey of adherence to haemophilia therapy in six European countries: results and recommendations. Haemophilia 2008;14: 931-8
    • (2008) Haemophilia , vol.14 , pp. 931-938
    • De Moerloose, P.1    Urbancik, W.2    Van Den Berg, H.M.3
  • 52
    • 84860346032 scopus 로고    scopus 로고
    • The benefits of prophylaxis: Views of adolescents with severe haemophilia
    • Khair K, Gibson F, Meerabeau L. The benefits of prophylaxis: views of adolescents with severe haemophilia. Haemophilia 2011;18:e286-9
    • (2011) Haemophilia , vol.18 , pp. e286-e289
    • Khair, K.1    Gibson, F.2    Meerabeau, L.3
  • 53
    • 84867166712 scopus 로고    scopus 로고
    • Association between physical activity and risk of bleeding in children with hemophilia
    • Broderick CR, Herbert RD, Latimer J, et al. Association between physical activity and risk of bleeding in children with hemophilia. JAMA 2012;308:1452-9
    • (2012) JAMA , vol.308 , pp. 1452-1459
    • Broderick, C.R.1    Herbert, R.D.2    Latimer, J.3
  • 54
    • 84924428351 scopus 로고    scopus 로고
    • Is bleeding in hemophilia really spontaneous or activity related: Analysis of US patient/caregiver data from the Hemophilia Experiences, Results and Opportunities (HERO) study
    • December 7-10; New Orleans, LA
    • Valentino LA, Forsyth A, Witkop M, et al. Is bleeding in hemophilia really spontaneous or activity related: Analysis of US patient/caregiver data from the Hemophilia Experiences, Results and Opportunities (HERO) study. Presented at: American Society of Hematology Annual Meeting. December 7-10; New Orleans, LA; 2013
    • (2013) Presented At: American Society of Hematology Annual Meeting
    • Valentino, L.A.1    Forsyth, A.2    Witkop, M.3
  • 55
    • 69949085125 scopus 로고    scopus 로고
    • Factor VIII prophylaxis for adult patients with severe haemophilia A: Results of a US survey of attitudes and practices
    • Walsh CE, Valentino LA. Factor VIII prophylaxis for adult patients with severe haemophilia A: results of a US survey of attitudes and practices. Haemophilia 2009;15:1014-21
    • (2009) Haemophilia , vol.15 , pp. 1014-1021
    • Walsh, C.E.1    Valentino, L.A.2
  • 56
    • 73049092113 scopus 로고    scopus 로고
    • Efficacy and safety of secondary prophylactic vs. On-demand sucrose-formulated recombinant factor VIII treatment in adults with severe hemophilia A: Results from a 13-month crossover study
    • Collins P, Faradji A, Morfini M, et al. Efficacy and safety of secondary prophylactic vs. on-demand sucrose-formulated recombinant factor VIII treatment in adults with severe hemophilia A: results from a 13-month crossover study. J Thromb Haemost 2010;8:83-9
    • (2010) J Thromb Haemost , vol.8 , pp. 83-89
    • Collins, P.1    Faradji, A.2    Morfini, M.3
  • 57
    • 84924426992 scopus 로고    scopus 로고
    • Impact on healthcare costs and quality of life of secondary prophylaxis in adolescent and adult patients with severe haemophilia A: The POTTER study [abstract PA 1.13-2]
    • Tagliaferri A, Coppola A, Feola G, et al. Impact on healthcare costs and quality of life of secondary prophylaxis in adolescent and adult patients with severe haemophilia A: The POTTER study [abstract PA 1.13-2]. J Thromb Haemost 2013;11:321-2
    • (2013) J Thromb Haemost , vol.11 , pp. 321-322
    • Tagliaferri, A.1    Coppola, A.2    Feola, G.3
  • 58
    • 84924428350 scopus 로고    scopus 로고
    • A diagnostic, cross-sectional evaluation of joint status using magnetic resonance imaging in patients with severe hemophilia A treated with prophylaxis versus on-demand therapy
    • July 8-12, Paris, France
    • Oldenburg J, Zimmermann R, Katsarou O, et al. A diagnostic, cross-sectional evaluation of joint status using magnetic resonance imaging in patients with severe hemophilia A treated with prophylaxis versus on-demand therapy. Presented at: World Federation of Hemophilia World Congress. July 8-12, Paris, France; 2012
    • (2012) Presented At: World Federation of Hemophilia World Congress
    • Oldenburg, J.1    Zimmermann, R.2    Katsarou, O.3
  • 59
    • 84898914046 scopus 로고    scopus 로고
    • Multicentre, randomized, open-label study of on-demand treatment with two prophylaxis regimens of recombinant coagulation factor IX in haemophilia B subjects
    • Valentino LA, Rusen L, Elezovic I, et al. Multicentre, randomized, open-label study of on-demand treatment with two prophylaxis regimens of recombinant coagulation factor IX in haemophilia B subjects. Haemophilia 2014;20:398-406
    • (2014) Haemophilia , vol.20 , pp. 398-406
    • Valentino, L.A.1    Rusen, L.2    Elezovic, I.3
  • 60
    • 84857572936 scopus 로고    scopus 로고
    • A randomized comparison of two prophylaxis regimens and a paired comparison of on-demand and prophylaxis treatments in hemophilia A management
    • Valentino LA, Mamonov V, Hellmann A, et al. A randomized comparison of two prophylaxis regimens and a paired comparison of on-demand and prophylaxis treatments in hemophilia A management. J Thromb Haemost 2012;10:359-67
    • (2012) J Thromb Haemost , vol.10 , pp. 359-367
    • Valentino, L.A.1    Mamonov, V.2    Hellmann, A.3
  • 61
    • 84894286025 scopus 로고    scopus 로고
    • ADVATE prophylaxis: Post hoc analysis of joint bleeding episodes
    • [Epub ahead of print]
    • Valentino LA, Reyes CM, Ewenstein B, et al. ADVATE prophylaxis: post hoc analysis of joint bleeding episodes. Haemophilia 2014. [Epub ahead of print]
    • (2014) Haemophilia
    • Valentino, L.A.1    Reyes, C.M.2    Ewenstein, B.3
  • 62
    • 74749088081 scopus 로고    scopus 로고
    • Factor VIII requirement to maintain a target plasma level in the prophylactic treatment of severe haemophilia A: Influences of variance in pharmacokinetics and treatment regimens
    • Collins PW, Björkman S, Fischer K, et al. Factor VIII requirement to maintain a target plasma level in the prophylactic treatment of severe haemophilia A: influences of variance in pharmacokinetics and treatment regimens. J Thromb Haemost 2009;8:269-75
    • (2009) J Thromb Haemost , vol.8 , pp. 269-275
    • Collins, P.W.1    Björkman, S.2    Fischer, K.3
  • 63
    • 84868206189 scopus 로고    scopus 로고
    • Daily dosing prophylaxis for haemophilia: A randomized crossover pilot study evaluating feasibility and efficacy
    • Lindvall K, Astermark J, Bjorkman S, et al. Daily dosing prophylaxis for haemophilia: A randomized crossover pilot study evaluating feasibility and efficacy. Haemophilia 2012;18:855-9
    • (2012) Haemophilia , vol.18 , pp. 855-859
    • Lindvall, K.1    Astermark, J.2    Bjorkman, S.3
  • 64
    • 85027949267 scopus 로고    scopus 로고
    • Considerations in individualizing prophylaxis in patients with haemophilia A
    • Valentino LA. Considerations in individualizing prophylaxis in patients with haemophilia A. Haemophilia 2014;20: 607-15
    • (2014) Haemophilia , vol.20 , pp. 607-615
    • Valentino, L.A.1
  • 65
    • 84860348922 scopus 로고    scopus 로고
    • Past, present and future of hemophilia: A narrative review
    • Franchini M, Mannucci PM. Past, present and future of hemophilia: A narrative review. Orphanet J Rare Dis 2012;7:24
    • (2012) Orphanet J Rare Dis , vol.7 , pp. 24
    • Franchini, M.1    Mannucci, P.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.