Neoangiogenesis contributes to the development of hemophilic synovitis

Blood

Volumn 117, Issue 8, 2011, Pages 2484-2493

  Acharya, Suchitra S ^a,b   Kaplan, Rosandra N ^a,c,d,e   Macdonald, Dan ^a,c   Fabiyi, Oluwa T ^a,c   DiMichele, Donna ^a,f   Lyden, David ^a,c,d  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b Northwell Health   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD34 ANTIGEN; CD68 ANTIGEN; GELATINASE B; STROMAL CELL DERIVED FACTOR 1; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE MARKER; ENDOTHELIAL PROGENITOR CELL; ENDOTHELIUM CELL; HEMARTHROSIS; HEMATOPOIETIC STEM CELL; HEMOPHILIA; HUMAN; HUMAN CELL; HYPOXIA; MACROPHAGE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNOVIOCYTE; SYNOVITIS; SYNOVIUM; UPREGULATION;

EID: 79952177822     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-05-284653     Document Type: Article

References (39)

1. Manco-Johnson MJ, Riske B, Casper CK. Advances in care of children with hemophilia. Semin Thromb Haemost. 2003;29(6):585-594. (Pubitemid 38041410)
2. Rodriguez-Merchan EC. Pathogenesis, early diagnosis and prophylaxis for chronic hemophilic synovitis. Clin Orthop.1997;343:6-11. (Pubitemid 27450788)
3. Hoots WK. Pathogenesis of hemophilia arthropathy. Semin Hematol. 2006;43(suppl 1):S18-S22.
4. Madhok R, Bennett D, Sturrock RD, Forbes CD. Mechanisms of joint damage in an experimental model of hemophilic arthritis. Arthritis Rheum. 1988;31(9):1148-1155.
5. Manco-Johnson MJ, Abshire TC, Shapiro AD, et al. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia. N Engl J Med. 2007;357(6):535-544. (Pubitemid 47236278)
6. Mathew P, Talbut DC, Frogamein A, et al. Isotopic synovectomy with P-32 in paediatric patients with haemophilia. Haemophilia. 2000;6(5):547-555.
7. Verma N, Valentino LA, Chawla A. Arthroscopic synovectomy in hemophilia: indications, techniques and results. Haemophilia. 2007;13(3):38-44. (Pubitemid 47377658)
8. Nuss R, Kilcoyne RF, Geraghty S, et al. MRI findings in haemophilic joints treated with radiosynoviorthesis with development of an MRI scale of joint damage. Haemophilia. 2000;6(3):162-169. (Pubitemid 30312469)
9. Hooiveld M, Roosendaal G, Vianen M, et al. Blood-induced joint damage: long term effects in vitro and in vivo. J Rheumatol. 2003;30(2):339-344. (Pubitemid 36152601)
10. Hakobyan N, Kazarian T, Valentino LA. Synovitis in a murine model of human FVIII deficiency. Haemophilia. 2005;11(3):227-232. (Pubitemid 40723797)
11. Hakobyan N, Kazarian T, Jabbar AA, et al. Pathobiology of hemophilic synovitis: I. Overexpression of mdm2 oncogene. Blood. 2004;104(7):2060-2064. (Pubitemid 39297857)
12. Wen FQ, Jabbar AA, Chen YX, et al. C-myc protooncogene expression in hemophilic synovitis: in vitro studies on the effects of iron and ceramide. Blood. 2002;100(3):912-916. (Pubitemid 34832617)
13. Folkman J, Shing Y. Angiogenesis. J Biol Chem. 1992;267(16):10931-10934.
14. Joseph-Silverstein J, Rifkin DB. Endothelial cell growth factors and the vessel wall. Semin Thromb Hemost. 1987;13(4):504-513. (Pubitemid 18007753)
15. Ortega N, Jonca F, Vincent S, et al. Systemic activation of the vascular endothelial growth factor receptor KDR/flk-1 selectively triggers endothelial cells with an angiogenic phenotype. Am J Pathol. 1997;151(5):1215-1224. (Pubitemid 27479750)
16. Gerber HP, Condorelli F, Park J, Ferrara N. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes: Flt-1, but not Flk-1/KDR, is upregulated by hypoxia. J Biol Chem. 1997;272(38):23659- 23667. (Pubitemid 27410939)
17. Ruger B, Giurea A, Wanivenhaus AH, et al. Endothelial precursor cells in the synovial tissue of patients with rheumatoid arthritis and osteoarthritis. Arthritis Rheum. 2004;50(7):2157-2166. (Pubitemid 38924393)
18. Maeno N, Takei S, Imanaka H, et al. Increased circulating vascular endothelial growth factor is correlated with disease activity in polyarticular juvenile rheumatoid arthritis. J Rheumatol. 1999;26(10):2244-2248. (Pubitemid 29487025)
19. Sivakumar B, Akhwani MA, Winlove CP, et al. Synovial hypoxia as a cause of tendon rupture in rheumatoid arthritis. J Hand Surg Am. 2008;33(1):49-58. (Pubitemid 351193088)
20. Hakobyan N, Enockson C, Valentino LA. Experimental hemophilic arthropathy in a mouse model of a massive hemarthrosis: gross, radiological, and histological changes. Haemophilia. 2008;14(4):804-809. (Pubitemid 352016038)
21. El-Sayed M, Kiani MF, Naimark MD, et al. Extravasation of poly(amidoamine)(PAMAM) dendrimers across microvascular network endothelium. Pharm Res. 2001;18(1):23-28. (Pubitemid 32299618)
22. Karajannis MA, Vincent L, Direnzo R, et al. Activation of FGFR1beta signaling pathway promotes survival, migration and resistance to chemotherapy in acute myeloid leukemia cells. Leukemia. 2006;20(6):979-986. (Pubitemid 43797288)
23. Greevers LC, van Lent PL, Koenders MI, et al. Different amplifying mechanisms of interleukin-17 and interferon G in Fc G-receptor mediated cartilage destruction in murine immune complex-mediated arthritis. Arthritis Rheum. 2009;60(2):396-407.
24. Kaplan RN, Riba RD, Zacharoulis S, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature. 2005;438(7069):820-827. (Pubitemid 41753060)
25. Heissig B, Hattori K, Dias S, Friedrich M, et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell. 2002;109(5):625-637. (Pubitemid 34628725)
26. Hwang JH, Kim SW, Park SE, et al. Overexpression of stromal cell-derived factor-1 enhances endothelium-supported transmigration, maintenance, and proliferation of hematopoietic progenitor cells. Stem Cells Dev. 2006;15(2):260-268.
27. Lyden D, Hattori K, Dias S, et al. Impairment of bone marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth. Nat Med. 2001;7(11):1194-1201. (Pubitemid 33063774)
28. Gao D, Nolan DJ, Mellick AS, et al. Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science. 2008;319(5860):195-198.
29. Eubank TD, Galloway M, Montague CM, et al. M-CSF induces vascular endothelial growth factor production and angiogenic activity from human monocytes. J Immunol. 2003;171(5):2637-2643. (Pubitemid 37025577)
30. Yang C, Zhang ZH, Li ZJ, et al. Enhancement of neovascularization with cord blood CD133+ cell-derived endothelial progenitor cell transplantation. Thromb Haemost. 2004;91(6):1202-1212. (Pubitemid 38821278)
31. Ceradini DJ, Kulkarni AR, Callaghan MJ, et al. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med. 2004;10(8):858-864. (Pubitemid 39070860)
32. Roosendaal G, TeKoppele JM, Vianen ME, et al. Blood-induced joint damage: a canine in vivo study. Arthritis Rheum. 1999;42(5):1033-1039. (Pubitemid 29215016)
33. Bresnihan B, Gerlag DM, Rooney T, et al. Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: standardization and consistency across centers. J Rheumatol. 2007;34(3):620-622. (Pubitemid 46364021)
34. Iwanaga T, Shikhichi M, Kitamura H, et al. Morphology and functional roles of synoviocytes in the joint. Arch Histol Cytol. 2000;63(1):17-31. (Pubitemid 30202189)
35. Ballara S, Taylor PC, Reusch P, et al. Raised serum vascular growth factor levels are associated with destructive change in inflammatory arthritis. Arthritis Rheum. 2001;44(9):2055-2064. (Pubitemid 33644048)
36. Oliver SJ, Cheng TP, Banquerigo ML, Brahn E. Suppression of collagen-induced arthritis by an angiogenesis inhibitor, AGM-1470 in combination with cyclosporine: reduction of vascular endothelial growth factor. Cell Immunol. 1995;166:196-206. (Pubitemid 26011492)
37. Heffler LA, Zeillinger R, Grimm C, et al. Preoperative serum vascular endothelial growth factor as a prognostic parameter in ovarian cancer. Gynecol Oncol. 2006;103(2):512-517. (Pubitemid 44740099)
38. Peled A, Kollet O, Ponomaryov T, et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34 (-) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. Blood. 2000;95(11):3289-3296. (Pubitemid 30428455)
39. Lane WJ, Dias S, Hattori K, et al. Stromal-derived factor-1-induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases. Blood. 2000;96(13):4152-4159.