DNA methylation analysis of homeobox genes implicates HOXB7 hypomethylation as risk factor for neural tube defects

Epigenetics

Volumn 10, Issue 1, 2015, Pages 92-101

  Rochtus, Anne ^a,b   Izzi, Benedetta ^a   Vangeel, Elise ^c   Louwette, Sophie ^a   Wittevrongel, Christine ^a   Lambrechts, Diether ^d,e   Moreau, Yves ^c   Winand, Raf ^c   Verpoorten, Carla ^b   Jansen, Katrien ^b   van Geet, Chris ^a,b   Freson, Kathleen ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^e UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

DNA methylation; Epigenetics; HOX genes; HOXB7; Myelomeningocele; Neural tube defects

Indexed keywords

HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR PAX2; HOXB7 PROTEIN, HUMAN; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MTHFR PROTEIN, HUMAN;

ADULT; ARTICLE; CASE CONTROL STUDY; CENTRAL PATTERN GENERATOR; CLINICAL ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DNA METHYLATION; EMBRYO DEVELOPMENT; EPIGENETICS; FEMALE; GENE; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HOXB7 GENE; HUMAN; IN SITU HYBRIDIZATION; MALE; MENINGOMYELOCELE; NEURAL TUBE DEFECT; NONHUMAN; RISK FACTOR; ZEBRA FISH; ANIMAL; CPG ISLAND; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; GENOME; METABOLISM; NEWBORN; SINGLE NUCLEOTIDE POLYMORPHISM;

DANIO RERIO;

ADULT; ANIMALS; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOME; HOMEODOMAIN PROTEINS; HUMANS; INFANT, NEWBORN; MALE; MENINGOMYELOCELE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); POLYMORPHISM, SINGLE NUCLEOTIDE; ZEBRAFISH;

EID: 84924405857     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2014.998531     Document Type: Article

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