Tetramers reveal IL-17-secreting CD4+ T cells that are specific for U1-70 in lupus and mixed connective tissue disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 10, 2015, Pages 3044-3049

  Kattah, Nicole H ^a   Newell, Evan W ^a   Jarrell, Justin Ansel ^a   Chu, Alvina D ^a   Xie, Jianming ^a   Kattah, Michael G ^a   Goldberger, Ofir ^a   Ye, Jessica ^a   Chakravarty, Eliza F ^a   Davis, Mark M ^a   Utz, Paul J ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmunity; IL 17; Lupus; SLE; Tetramer

Indexed keywords

AUTOANTIGEN; EPITOPE; GAMMA INTERFERON; IMMUNOGLOBULIN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOGLOBULIN G3 ANTIBODY; INTERLEUKIN 17; INTERLEUKIN 6; MONOMER; PROTEIN; TETRAMER; TRANSFORMING GROWTH FACTOR BETA; U1 70 PROTEIN; UNCLASSIFIED DRUG; AUTOANTIBODY; OLIGOPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; LYMPHADENOPATHY; MIXED CONNECTIVE TISSUE DISEASE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEINURIA; SYSTEMIC LUPUS ERYTHEMATOSUS; T CELL CULTURE; TH17 CELL; ANIMAL; BIOSYNTHESIS; IMMUNOLOGY; MALE; PHOSPHORYLATION; SECRETION (PROCESS);

MUS;

ANIMALS; AUTOANTIBODIES; CD4-POSITIVE T-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INTERLEUKIN-17; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MICE; MIXED CONNECTIVE TISSUE DISEASE; OLIGOPEPTIDES; PHOSPHORYLATION;

EID: 84924308789     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1424796112     Document Type: Article

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