메뉴 건너뛰기




Volumn 16, Issue 1, 2015, Pages

Global transcriptomic profiling demonstrates induction of oxidative stress and of compensatory cellular stress responses in brown trout exposed to glyphosate and Roundup

Author keywords

Herbicide; RNA seq; Salmonids; Toxicogenomics; Transcriptome

Indexed keywords

GLYPHOSATE; HEAT SHOCK PROTEIN; HERBICIDE; ROUNDUP; TRANSCRIPTOME; UNCLASSIFIED DRUG; ANTIOXIDANT; GLYCINE;

EID: 84924294360     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1254-5     Document Type: Article
Times cited : (100)

References (65)
  • 1
    • 0035852781 scopus 로고    scopus 로고
    • Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail
    • Schonbrunn E, Eschenburg S, Shuttleworth WA, Schloss JV, Amrhein N, Evans JNS, et al. Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail. Proc Natl Acad Sci. 2001;98(4):1376-80.
    • (2001) Proc Natl Acad Sci , vol.98 , Issue.4 , pp. 1376-1380
    • Schonbrunn, E.1    Eschenburg, S.2    Shuttleworth, W.A.3    Schloss, J.V.4    Amrhein, N.5    Evans, J.N.S.6
  • 2
    • 0018932939 scopus 로고
    • The herbicide glyphosate is a potent inhibitor of 5-enolpyruvylshikimic acid-3-phosphate synthase
    • Steinrucken HC, Amrhein N. The herbicide glyphosate is a potent inhibitor of 5-enolpyruvylshikimic acid-3-phosphate synthase. Biochem Biophys Res Commun. 1980;94(4):1207-12.
    • (1980) Biochem Biophys Res Commun , vol.94 , Issue.4 , pp. 1207-1212
    • Steinrucken, H.C.1    Amrhein, N.2
  • 3
    • 84924332158 scopus 로고    scopus 로고
    • The use of plant protection products in the European Union- Data 1992-2003
    • Luxembourg: Official Publications of the European Communities
    • European Commission. The use of plant protection products in the European Union- Data 1992-2003. In: Eurostat Statistical books. Luxembourg: Official Publications of the European Communities; 2007.
    • (2007) Eurostat Statistical books
  • 5
    • 69349100919 scopus 로고    scopus 로고
    • Transfer of glyphosate and its degradate AMPA to surface waters through urban sewerage systems
    • Botta F, Lavison G, Couturier G, Alliot F, Moreau-Guigon E, Fauchon N, et al. Transfer of glyphosate and its degradate AMPA to surface waters through urban sewerage systems. Chemosphere. 2009;77(1):133-9.
    • (2009) Chemosphere , vol.77 , Issue.1 , pp. 133-139
    • Botta, F.1    Lavison, G.2    Couturier, G.3    Alliot, F.4    Moreau-Guigon, E.5    Fauchon, N.6
  • 6
    • 33845763442 scopus 로고    scopus 로고
    • Toxicity of three polyethoxylated tallowamine surfactant formulations to laboratory and field collected fairy shrimp, Thamnocephalus platyurus
    • Brausch JM, Smith PN. Toxicity of three polyethoxylated tallowamine surfactant formulations to laboratory and field collected fairy shrimp, Thamnocephalus platyurus. Arch Environ Contam Toxicol. 2007;52(2):217-21.
    • (2007) Arch Environ Contam Toxicol , vol.52 , Issue.2 , pp. 217-221
    • Brausch, J.M.1    Smith, P.N.2
  • 8
    • 49749134326 scopus 로고    scopus 로고
    • Low cost monitoring of glyphosate in surface waters using the ELISA method: An evaluation
    • Byer JD, Struger J, Klawunn P, Todd A, Sverko E. Low cost monitoring of glyphosate in surface waters using the ELISA method: An evaluation. Environ Sci Technol. 2008;42(16):6052-7.
    • (2008) Environ Sci Technol , vol.42 , Issue.16 , pp. 6052-6057
    • Byer, J.D.1    Struger, J.2    Klawunn, P.3    Todd, A.4    Sverko, E.5
  • 10
    • 68149150654 scopus 로고    scopus 로고
    • The occurrence of glyphosate, atrazine, and other pesticides in vernal pools and adjacent streams in Washington, DC, Maryland, Iowa, and Wyoming, 2005-2006
    • Battaglin WA, Rice KC, Focazio MJ, Salmons S, Barry RX. The occurrence of glyphosate, atrazine, and other pesticides in vernal pools and adjacent streams in Washington, DC, Maryland, Iowa, and Wyoming, 2005-2006. Environ Monit Assess. 2009;155(1):281-307.
    • (2009) Environ Monit Assess , vol.155 , Issue.1 , pp. 281-307
    • Battaglin, W.A.1    Rice, K.C.2    Focazio, M.J.3    Salmons, S.4    Barry, R.X.5
  • 13
    • 71849089168 scopus 로고    scopus 로고
    • Roundup causes oxidative stress in liver and inhibits acetylcholinesterase in muscle and brain of the fish Prochilodus lineatus
    • Modesto KA, Martinez CB. Roundup causes oxidative stress in liver and inhibits acetylcholinesterase in muscle and brain of the fish Prochilodus lineatus. Chemosphere. 2010;78(3):294-9.
    • (2010) Chemosphere , vol.78 , Issue.3 , pp. 294-299
    • Modesto, K.A.1    Martinez, C.B.2
  • 14
    • 34547690813 scopus 로고    scopus 로고
    • Detection of cytogenetic and DNA damage in peripheral erythrocytes of goldfish (Carassius auratus) exposed to a glyphosate formulation using the micronucleus test and the comet assay
    • Cavas T, Konen S. Detection of cytogenetic and DNA damage in peripheral erythrocytes of goldfish (Carassius auratus) exposed to a glyphosate formulation using the micronucleus test and the comet assay. Mutagenesis. 2007;22(4):263-8.
    • (2007) Mutagenesis , vol.22 , Issue.4 , pp. 263-268
    • Cavas, T.1    Konen, S.2
  • 15
    • 77956235304 scopus 로고    scopus 로고
    • European eel (Anguilla anguilla) genotoxic and pro-oxidant responses following short-term exposure to Roundup®, a glyphosate-based herbicide
    • Guilherme S, Gaivao I, Santos M, Pacheco M. European eel (Anguilla anguilla) genotoxic and pro-oxidant responses following short-term exposure to Roundup®, a glyphosate-based herbicide. Mutagenesis. 2010;25(5):523-30.
    • (2010) Mutagenesis , vol.25 , Issue.5 , pp. 523-530
    • Guilherme, S.1    Gaivao, I.2    Santos, M.3    Pacheco, M.4
  • 16
    • 84865018658 scopus 로고    scopus 로고
    • Differential genotoxicity of Roundup® formulation and its constituents in blood cells of fish (Anguilla anguilla): considerations on chemical interactions and DNA damaging mechanisms
    • Guilherme S, Santos M, Barroso C, Gaivao I, Pacheco M. Differential genotoxicity of Roundup® formulation and its constituents in blood cells of fish (Anguilla anguilla): considerations on chemical interactions and DNA damaging mechanisms. Ecotoxicol. 2012;21(5):1381-90.
    • (2012) Ecotoxicol , vol.21 , Issue.5 , pp. 1381-1390
    • Guilherme, S.1    Santos, M.2    Barroso, C.3    Gaivao, I.4    Pacheco, M.5
  • 17
    • 84876337129 scopus 로고    scopus 로고
    • Genotoxic effects of the herbicide Roundup in the fish Corydoras paleatus (Jenyns 1842) after short-term, environmentally low concentration exposure
    • de Castilhos Ghisi N, Cestari MM. Genotoxic effects of the herbicide Roundup in the fish Corydoras paleatus (Jenyns 1842) after short-term, environmentally low concentration exposure. Environ Monit Assess. 2013;185(4):1-7.
    • (2013) Environ Monit Assess , vol.185 , Issue.4 , pp. 1-7
    • Castilhos Ghisi, N.1    Cestari, M.M.2
  • 18
    • 70349473083 scopus 로고    scopus 로고
    • Oxidative stress responses of rats exposed to Roundup and its active ingredient glyphosate
    • El-Shenawy NS. Oxidative stress responses of rats exposed to Roundup and its active ingredient glyphosate. Environ Toxicol Pharmacol. 2009;28(3):379-85.
    • (2009) Environ Toxicol Pharmacol , vol.28 , Issue.3 , pp. 379-385
    • El-Shenawy, N.S.1
  • 19
    • 70249120657 scopus 로고    scopus 로고
    • Effect of pesticides on cell survival in liver and brain rat tissues
    • Astiz M, Alaniz MJ, Marra CA. Effect of pesticides on cell survival in liver and brain rat tissues. Ecotoxicol Environ Saf. 2009;72(7):2025-32.
    • (2009) Ecotoxicol Environ Saf , vol.72 , Issue.7 , pp. 2025-2032
    • Astiz, M.1    Alaniz, M.J.2    Marra, C.A.3
  • 21
    • 84856508485 scopus 로고    scopus 로고
    • A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cells in vitro, and testosterone decrease at lower levels
    • Clair A, Mesnage R, Travert C, Seralini GE. A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cells in vitro, and testosterone decrease at lower levels. Toxicol in Vitro. 2012;26(2):269-79.
    • (2012) Toxicol in Vitro , vol.26 , Issue.2 , pp. 269-279
    • Clair, A.1    Mesnage, R.2    Travert, C.3    Seralini, G.E.4
  • 22
    • 84869446482 scopus 로고    scopus 로고
    • Mixtures of glyphosate and surfactant TN20 accelerate cell death via mitochondrial damage-induced apoptosis and necrosis
    • Y-h K, Hong J-R, Gil H-W, Song H-Y, Hong S-Y. Mixtures of glyphosate and surfactant TN20 accelerate cell death via mitochondrial damage-induced apoptosis and necrosis. Toxicol in Vitro. 2013;1:191-7.
    • (2013) Toxicol in Vitro , vol.1 , pp. 191-197
    • Y-h, K.1    Hong, J.-R.2    Gil, H.-W.3    Song, H.-Y.4    Hong, S.-Y.5
  • 23
    • 84888270947 scopus 로고    scopus 로고
    • Ethoxylated adjuvants of glyphosate-based herbicides are active principles of human cell toxicity
    • Mesnage R, Bernay B, Seralini G-E. Ethoxylated adjuvants of glyphosate-based herbicides are active principles of human cell toxicity. Toxicology. 2013;313:122-8.
    • (2013) Toxicology , vol.313 , pp. 122-128
    • Mesnage, R.1    Bernay, B.2    Seralini, G.-E.3
  • 24
    • 61849171735 scopus 로고    scopus 로고
    • Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells
    • Benachour N, Seralini G-E. Glyphosate formulations induce apoptosis and necrosis in human umbilical, embryonic, and placental cells. Chem Res Toxicol. 2008;22(1):97-105.
    • (2008) Chem Res Toxicol , vol.22 , Issue.1 , pp. 97-105
    • Benachour, N.1    Seralini, G.-E.2
  • 25
    • 0033790179 scopus 로고    scopus 로고
    • Roundup inhibits steroidogenesis by disrupting steroidogenic acute regulatory (StAR) protein expression
    • Walsh LP, McCormick C, Martin C, Stocco DM. Roundup inhibits steroidogenesis by disrupting steroidogenic acute regulatory (StAR) protein expression. Environ Health Perspect. 2000;108(8):769-74.
    • (2000) Environ Health Perspect , vol.108 , Issue.8 , pp. 769-774
    • Walsh, L.P.1    McCormick, C.2    Martin, C.3    Stocco, D.M.4
  • 26
    • 84862835878 scopus 로고    scopus 로고
    • Glyphosate impairs male offspring reproductive development by disrupting gonadotropin expression
    • Romano MA, Romano RM, Santos LD, Wisniewski P, Campos DA, de Souza PB, et al. Glyphosate impairs male offspring reproductive development by disrupting gonadotropin expression. Arch Toxicol. 2012;86(4):663-73.
    • (2012) Arch Toxicol , vol.86 , Issue.4 , pp. 663-673
    • Romano, M.A.1    Romano, R.M.2    Santos, L.D.3    Wisniewski, P.4    Campos, D.A.5    Souza, P.B.6
  • 28
    • 84892704107 scopus 로고    scopus 로고
    • Effects of Glyphosate and its Formulation, Roundup, on Reproduction in Zebrafish (Danio rerio)
    • Uren Webster TM, Laing LV, Florance H, Santos EM. Effects of Glyphosate and its Formulation, Roundup, on Reproduction in Zebrafish (Danio rerio). Environ Sci Technol. 2014;48(2):1271-9.
    • (2014) Environ Sci Technol , vol.48 , Issue.2 , pp. 1271-1279
    • Uren Webster, T.M.1    Laing, L.V.2    Florance, H.3    Santos, E.M.4
  • 29
    • 77951167222 scopus 로고    scopus 로고
    • Synergistic effects of glyphosate formulation and parasite infection on fish malformations and survival
    • Kelly DW, Poulin R, Tompkins DM, Townsend CR. Synergistic effects of glyphosate formulation and parasite infection on fish malformations and survival. J Appl Ecol. 2010;47(2):498-504.
    • (2010) J Appl Ecol , vol.47 , Issue.2 , pp. 498-504
    • Kelly, D.W.1    Poulin, R.2    Tompkins, D.M.3    Townsend, C.R.4
  • 31
    • 84859522752 scopus 로고    scopus 로고
    • New effects of roundup on amphibians: predators reduce herbicide mortality; herbicides induce antipredator morphology
    • Relyea RA. New effects of roundup on amphibians: predators reduce herbicide mortality; herbicides induce antipredator morphology. Ecol Appl. 2012;22(2):634-47.
    • (2012) Ecol Appl , vol.22 , Issue.2 , pp. 634-647
    • Relyea, R.A.1
  • 32
    • 41349092257 scopus 로고    scopus 로고
    • Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals
    • Paull GC, Van Look KJW, Santos EM, Filby AL, Gray DM, Nash JP, et al. Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals. Aquat Toxicol. 2008;87:115-26.
    • (2008) Aquat Toxicol , vol.87 , pp. 115-126
    • Paull, G.C.1    Look, K.J.W.2    Santos, E.M.3    Filby, A.L.4    Gray, D.M.5    Nash, J.P.6
  • 33
    • 77955883388 scopus 로고    scopus 로고
    • Biases in Illumina transcriptome sequencing caused by random hexamer priming
    • Hansen KD, Brenner SE, Dudoit S. Biases in Illumina transcriptome sequencing caused by random hexamer priming. Nucleic Acids Res. 2010;38(12):e131.
    • (2010) Nucleic Acids Res , vol.38 , Issue.12 , pp. e131
    • Hansen, K.D.1    Brenner, S.E.2    Dudoit, S.3
  • 35
    • 84877801923 scopus 로고    scopus 로고
    • A comparison across non-model animals suggests an optimal sequencing depth for de novo transcriptome assembly
    • Francis WR, Christianson LM, Kiko R, Powers ML, Shaner NC, Haddock SH. A comparison across non-model animals suggests an optimal sequencing depth for de novo transcriptome assembly. BMC Genomics. 2013;14(1):167-73.
    • (2013) BMC Genomics , vol.14 , Issue.1 , pp. 167-173
    • Francis, W.R.1    Christianson, L.M.2    Kiko, R.3    Powers, M.L.4    Shaner, N.C.5    Haddock, S.H.6
  • 36
    • 43149115851 scopus 로고    scopus 로고
    • Velvet: Algorithms for de novo short read assembly using de Bruijn graphs
    • Zerbino DR, Birney E. Velvet: Algorithms for de novo short read assembly using de Bruijn graphs. Genome Res. 2008;18(5):821-9.
    • (2008) Genome Res , vol.18 , Issue.5 , pp. 821-829
    • Zerbino, D.R.1    Birney, E.2
  • 37
    • 84859768479 scopus 로고    scopus 로고
    • Oases: Robust de novo RNA-seq assembly across the dynamic range of expression levels
    • Schulz MH, Zerbino DR, Vingron M, Birney E. Oases: Robust de novo RNA-seq assembly across the dynamic range of expression levels. Bioinformatics. 2012;28(8):1086-92.
    • (2012) Bioinformatics , vol.28 , Issue.8 , pp. 1086-1092
    • Schulz, M.H.1    Zerbino, D.R.2    Vingron, M.3    Birney, E.4
  • 39
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with Bowtie 2
    • Langmead B, Salzberg SL. Fast gapped-read alignment with Bowtie 2. Nat Methods. 2012;9:357-9.
    • (2012) Nat Methods , vol.9 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 41
    • 75249087100 scopus 로고    scopus 로고
    • edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
    • Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 2010;26(1):139-40.
    • (2010) Bioinformatics , vol.26 , Issue.1 , pp. 139-140
    • Robinson, M.D.1    McCarthy, D.J.2    Smyth, G.K.3
  • 42
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang DW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2008;4(1):44-57.
    • (2008) Nat Protoc , vol.4 , Issue.1 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 43
    • 84873719491 scopus 로고    scopus 로고
    • Comparative study of de novo assembly and genome-guided assembly strategies for transcriptome reconstruction based on RNA-Seq
    • Lu B, Zeng Z, Shi T. Comparative study of de novo assembly and genome-guided assembly strategies for transcriptome reconstruction based on RNA-Seq. Sci China Life Sci. 2013;56(2):143-55.
    • (2013) Sci China Life Sci , vol.56 , Issue.2 , pp. 143-155
    • Lu, B.1    Zeng, Z.2    Shi, T.3
  • 44
    • 84859373425 scopus 로고    scopus 로고
    • Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
    • Vandenberg LN, Colborn T, Hayes TB, Heindel JJ, Jacobs Jr DR, Lee D-H, et al. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev. 2012;33(3):378-455.
    • (2012) Endocr Rev , vol.33 , Issue.3 , pp. 378-455
    • Vandenberg, L.N.1    Colborn, T.2    Hayes, T.B.3    Heindel, J.J.4    Jacobs, D.R.5    Lee, D.-H.6
  • 45
    • 1642504765 scopus 로고    scopus 로고
    • Nonmonotonic dose-response relationships: mechanistic basis, kinetic modeling, and implications for risk assessment
    • Conolly RB, Lutz WK. Nonmonotonic dose-response relationships: mechanistic basis, kinetic modeling, and implications for risk assessment. Toxicol Sci. 2004;77(1):151-7.
    • (2004) Toxicol Sci , vol.77 , Issue.1 , pp. 151-157
    • Conolly, R.B.1    Lutz, W.K.2
  • 46
    • 84890152730 scopus 로고    scopus 로고
    • Effects of Herbicides on Fish
    • Tierney KB, Farrell AP, Brauner CJ, editors, London: Elsevier
    • Solomon KR, Dalhoff K, Volz D, Van der Kraak G. Effects of Herbicides on Fish. In: Tierney KB, Farrell AP, Brauner CJ, editors. Fish physiology Vol 33. London: Elsevier; 2013. p. 369-409.
    • (2013) Fish physiology , vol.33 , pp. 369-409
    • Solomon, K.R.1    Dalhoff, K.2    Volz, D.3    Kraak, G.4
  • 47
    • 0036260697 scopus 로고    scopus 로고
    • Cellular response to oxidative stress: Signaling for suicide and survival*
    • Martindale JL, Holbrook NJ. Cellular response to oxidative stress: Signaling for suicide and survival*. J Cell Physiol. 2002;192(1):1-15.
    • (2002) J Cell Physiol , vol.192 , Issue.1 , pp. 1-15
    • Martindale, J.L.1    Holbrook, N.J.2
  • 48
    • 0036775158 scopus 로고    scopus 로고
    • Heme oxygenase-1: redox regulation and role in the hepatic response to oxidative stress
    • Bauer M, Bauer I. Heme oxygenase-1: redox regulation and role in the hepatic response to oxidative stress. Antioxid Redox Signal. 2002;4(5):749-58.
    • (2002) Antioxid Redox Signal , vol.4 , Issue.5 , pp. 749-758
    • Bauer, M.1    Bauer, I.2
  • 49
    • 84951174715 scopus 로고    scopus 로고
    • Reactive Oxygen Species and Oxidative Stress
    • Di Gulio RT, Hinton DE, editors. Boco Raton: Taylor and Francis
    • Di Giulio RT, Meyer JN. Reactive Oxygen Species and Oxidative Stress. In: Di Gulio RT, Hinton DE, editors. The Toxicology of Fishes. Boco Raton: Taylor and Francis; 2008. p. 273-301.
    • (2008) The Toxicology of Fishes , pp. 273-301
    • Giulio, R.T.1    Meyer, J.N.2
  • 50
    • 0012196927 scopus 로고    scopus 로고
    • Cell Proliferation, Differentiation, and Apoptosis
    • Edited by Bast RC, Pollock RE, 5th edn: Hamilton (ON): BC Decker
    • Andreef M, Goodrich DW, Pardee AB: Cell Proliferation, Differentiation, and Apoptosis. In: Holland-Frei Cancer Medicine. Edited by Bast RC, Pollock RE, 5th edn: Hamilton (ON): BC Decker; 2000.
    • (2000) Holland-Frei Cancer Medicine
    • Andreef, M.1    Goodrich, D.W.2    Pardee, A.B.3
  • 51
    • 43749092334 scopus 로고    scopus 로고
    • Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis
    • Mates J, Segura JA, Alonso FJ, Marquez J. Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis, and carcinogenesis. Arch Toxicol. 2008;82(5):273-99.
    • (2008) Arch Toxicol , vol.82 , Issue.5 , pp. 273-299
    • Mates, J.1    Segura, J.A.2    Alonso, F.J.3    Marquez, J.4
  • 52
    • 70149097778 scopus 로고    scopus 로고
    • Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2
    • Welch C, Santra MK, El-Assaad W, Zhu X, Huber WE, Keys RA, et al. Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2. Cancer Res. 2009;69(17):6782-9.
    • (2009) Cancer Res , vol.69 , Issue.17 , pp. 6782-6789
    • Welch, C.1    Santra, M.K.2    El-Assaad, W.3    Zhu, X.4    Huber, W.E.5    Keys, R.A.6
  • 53
    • 84868197448 scopus 로고    scopus 로고
    • Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis
    • Ouyang L, Shi Z, Zhao S, Wang FT, Zhou TT, Liu B, et al. Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif. 2012;45(6):487-98.
    • (2012) Cell Prolif , vol.45 , Issue.6 , pp. 487-498
    • Ouyang, L.1    Shi, Z.2    Zhao, S.3    Wang, F.T.4    Zhou, T.T.5    Liu, B.6
  • 54
    • 0034995893 scopus 로고    scopus 로고
    • Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts
    • Siwik DA, Pagano PJ, Colucci WS. Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts. Am J Physiol Cell Physiol. 2001;280(1):C53-60.
    • (2001) Am J Physiol Cell Physiol , vol.280 , Issue.1 , pp. C53-60
    • Siwik, D.A.1    Pagano, P.J.2    Colucci, W.S.3
  • 55
    • 33745991798 scopus 로고    scopus 로고
    • Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts
    • Van Berkel W, Kamerbeek N, Fraaije M. Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts. J Biotechnol. 2006;124(4):670-89.
    • (2006) J Biotechnol , vol.124 , Issue.4 , pp. 670-689
    • Berkel, W.1    Kamerbeek, N.2    Fraaije, M.3
  • 56
    • 33745096264 scopus 로고    scopus 로고
    • Molecular identification and expression of differentially regulated genes of the European flounder, Platichthys flesus, submitted to pesticide exposure
    • Marchand J, Tanguy A, Charrier G, Quiniou L, Plee-Gauthier E, Laroche J. Molecular identification and expression of differentially regulated genes of the European flounder, Platichthys flesus, submitted to pesticide exposure. Mar Biotechnol. 2006;8(3):275-94.
    • (2006) Mar Biotechnol , vol.8 , Issue.3 , pp. 275-294
    • Marchand, J.1    Tanguy, A.2    Charrier, G.3    Quiniou, L.4    Plee-Gauthier, E.5    Laroche, J.6
  • 57
    • 12544253695 scopus 로고    scopus 로고
    • Molecular identification and expression study of differentially regulated genes in the Pacific oyster Crassostrea gigas in response to pesticide exposure
    • Tanguy A, Boutet I, Laroche J, Moraga D. Molecular identification and expression study of differentially regulated genes in the Pacific oyster Crassostrea gigas in response to pesticide exposure. FEBS J. 2005;272(2):390-403.
    • (2005) FEBS J , vol.272 , Issue.2 , pp. 390-403
    • Tanguy, A.1    Boutet, I.2    Laroche, J.3    Moraga, D.4
  • 58
    • 27644553925 scopus 로고    scopus 로고
    • Comparative effects of the Roundup and glyphosate on mitochondrial oxidative phosphorylation
    • Peixoto F. Comparative effects of the Roundup and glyphosate on mitochondrial oxidative phosphorylation. Chemosphere. 2005;61(8):1115-22.
    • (2005) Chemosphere , vol.61 , Issue.8 , pp. 1115-1122
    • Peixoto, F.1
  • 59
    • 77249179832 scopus 로고    scopus 로고
    • Responses of the European flounder Platichthys flesus to the chemical stress in estuaries: Load of contaminants, gene expression, cellular impact and growth rate
    • Evrard E, Devaux A, Bony S, Burgeot T, Riso R, Budzinski H, et al. Responses of the European flounder Platichthys flesus to the chemical stress in estuaries: Load of contaminants, gene expression, cellular impact and growth rate. Biomarkers. 2010;15(2):111-27.
    • (2010) Biomarkers , vol.15 , Issue.2 , pp. 111-127
    • Evrard, E.1    Devaux, A.2    Bony, S.3    Burgeot, T.4    Riso, R.5    Budzinski, H.6
  • 60
    • 84871617867 scopus 로고    scopus 로고
    • Effects of dietary cholesterol on antioxidant capacity, non-specific immune response, and resistance to Aeromonas hydrophila in rainbow trout (Oncorhynchus mykiss) fed soybean meal-based diets
    • Deng J, Kang B, Tao L, Rong H, Zhang X. Effects of dietary cholesterol on antioxidant capacity, non-specific immune response, and resistance to Aeromonas hydrophila in rainbow trout (Oncorhynchus mykiss) fed soybean meal-based diets. Fish Shellfish Immunol. 2013;34(1):324-31.
    • (2013) Fish Shellfish Immunol , vol.34 , Issue.1 , pp. 324-331
    • Deng, J.1    Kang, B.2    Tao, L.3    Rong, H.4    Zhang, X.5
  • 61
    • 56549116047 scopus 로고    scopus 로고
    • Toll-like Receptor and RIG-1-like Receptor Signaling
    • Kawai T, Akira S. Toll-like Receptor and RIG-1-like Receptor Signaling. Ann N Y Acad Sci. 2008;1143(1):1-20.
    • (2008) Ann N Y Acad Sci , vol.1143 , Issue.1 , pp. 1-20
    • Kawai, T.1    Akira, S.2
  • 62
  • 63
    • 0031955543 scopus 로고    scopus 로고
    • Effects of edifenphos and glyphosate on the immune response and protein biosynthesis of bolti fish (Tilapia nilotica)
    • El-Gendy K, Aly N, El-Sebae A. Effects of edifenphos and glyphosate on the immune response and protein biosynthesis of bolti fish (Tilapia nilotica). J Environ Sci Health Part B. 1998;33(2):135-49.
    • (1998) J Environ Sci Health Part B , vol.33 , Issue.2 , pp. 135-149
    • El-Gendy, K.1    Aly, N.2    El-Sebae, A.3
  • 64
    • 77955510561 scopus 로고    scopus 로고
    • Exposure to sublethal concentration of glyphosate or atrazine-based herbicides alters the phagocytic function and increases the susceptibility of silver catfish fingerlings (Rhamdia quelen) to Aeromonas hydrophila challenge
    • Kreutz LC, Gil Barcellos LJ, Marteninghe A, Davi dos Santos E, Zanatta R. Exposure to sublethal concentration of glyphosate or atrazine-based herbicides alters the phagocytic function and increases the susceptibility of silver catfish fingerlings (Rhamdia quelen) to Aeromonas hydrophila challenge. Fish Shellfish Immunol. 2010;29(4):694-7.
    • (2010) Fish Shellfish Immunol , vol.29 , Issue.4 , pp. 694-697
    • Kreutz, L.C.1    Gil Barcellos, L.J.2    Marteninghe, A.3    Davi dos Santos, E.4    Zanatta, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.