Oncogenic KRAS promotes malignant brain tumors in zebrafish

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Ju, Bensheng ^a   Chen, Wenbiao ^b   Orr, Brent A ^a   Spitsbergen, Jan M ^c   Jia, Sujuan ^a   Eden, Christopher J ^a   Henson, Hannah E ^a,d   Taylor, Michael R ^a,e  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c OREGON STATE UNIVERSITY   (United States)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Brain tumors; Drug screening; gfap; krt5; Oncogenic KRAS (KRASG12V); Zebrafish

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CYTOKERATIN 5; GLIAL FIBRILLARY ACIDIC PROTEIN; K RAS PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; RAF PROTEIN; RAS PROTEIN; KRAS PROTEIN, HUMAN; NERVE PROTEIN; ONCOPROTEIN; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TUMOR; CARCINOGENESIS; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISEASE COURSE; GENE CONTROL; GENE EXPRESSION; GENE FREQUENCY; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; MALIGNANT PERIPHERAL NERVE SHEATH TUMOR; MITOSIS INDEX; NONHUMAN; PARENCHYMA; PROMOTER REGION; SIGNAL TRANSDUCTION; SUBVENTRICULAR ZONE; ZEBRA FISH; ANIMAL; BRAIN; BRAIN NEOPLASMS; CELL TRANSFORMATION; DISEASE MODEL; DRUG SCREENING; GENETICS; HUMAN; METABOLISM; PATHOLOGY; TRANSGENE; TRANSGENIC ANIMAL;

DANIO RERIO; VERTEBRATA;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BRAIN; BRAIN NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; DRUG SCREENING ASSAYS, ANTITUMOR; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; KERATIN-5; NERVE TISSUE PROTEINS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSGENES; ZEBRAFISH;

EID: 84924277964     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/s12943-015-0288-2     Document Type: Article

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