Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin

DMM Disease Models and Mechanisms

Volumn 4, Issue 2, 2011, Pages 255-267

  Kim, Seok Hyung ^a   Speirs, Christina K ^a   Solnica Krezel, Lilianna ^a   Ess, Kevin C ^b  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HAMARTIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MUTANT PROTEIN; RHEB PROTEIN; TARGET OF RAPAMYCIN KINASE; TUBERIN;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN NERVE CELL; CELL COUNT; CELL MUTANT; CELL SIZE; DISEASE MODEL; ENZYME ACTIVITY; EYE; FOREBRAIN; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; GRAY MATTER; HAMARTOMA; HEART; HETEROZYGOTE; HOMOZYGOTE; IMMUNOFLUORESCENCE TEST; KIDNEY; LETHALITY; LUNG; NONHUMAN; NONSENSE MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SKIN; TARGETING INDUCED LOCAL LESIONS IN GENOME; TECHNIQUE; TUBEROUS SCLEROSIS; WESTERN BLOTTING; WHITE MATTER; WILD TYPE; ZEBRA FISH;

ANIMALS; BRAIN; CELL SIZE; CODON, NONSENSE; DISEASE MODELS, ANIMAL; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEPATOCYTES; HUMANS; LIVER; MUTANT PROTEINS; NEURONS; SIROLIMUS; TRANSCRIPTION FACTORS; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS; ZEBRAFISH;

ANIMALIA; DANIO RERIO;

EID: 79952345945     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.005587     Document Type: Article

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