A high level of liver-specific expression of oncogenic Kras V12 drives robust liver tumorigenesis in transgenic zebrafish

DMM Disease Models and Mechanisms

Volumn 4, Issue 6, 2011, Pages 801-813

  Nguyen, Anh Tuan ^a   Emelyanov, Alexander ^a   Koh, Chor Hui Vivien ^a   Spitsbergen, Jan M ^b   Lam, Siew Hong ^a   Mathavan, Sinnakaruppan ^c   Parinov, Serguei ^a   Gong, Zhiyuan ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b OREGON STATE UNIVERSITY   (United States)

^c GENOME INSTITUTE OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; FATTY ACID BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PROTEIN FABP10; PROTEIN KRAS V12; PROTEIN P53; RAF PROTEIN; RAS PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER MORTALITY; ENZYME ACTIVATION; GENE EXPRESSION; HISTOPATHOLOGY; LIVER CANCER; LIVER CARCINOGENESIS; LIVER HYPERPLASIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR GROWTH; ZEBRA FISH;

AGING; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARCINOMA, HEPATOCELLULAR; CELL TRANSFORMATION, NEOPLASTIC; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GREEN FLUORESCENT PROTEINS; HUMANS; LIVER; LIVER NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM TRANSPLANTATION; ONCOGENES; ORGAN SPECIFICITY; RAS PROTEINS; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN P53; WNT SIGNALING PATHWAY; ZEBRAFISH;

DANIO RERIO;

EID: 81455136715     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.007831     Document Type: Article

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