A neural circuit for circadian regulation of arousal

Nature Neuroscience

Volumn 4, Issue 7, 2001, Pages 732-738

  Aston Jones, Gary ^a   Chen, Sheng ^b   Zhu, Yan ^a   Oshinsky, Michael L ^c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b LONG ISLAND JEWISH MEDICAL CENTER   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; AROUSAL; ARTICLE; CIRCADIAN RHYTHM; LOCUS CERULEUS; NERVE PROJECTION; NONHUMAN; PRIORITY JOURNAL; SLEEP WAKING CYCLE; SUPRACHIASMATIC NUCLEUS;

ANIMALS; AROUSAL; CIRCADIAN RHYTHM; ELECTROPHYSIOLOGY; HERPESVIRUS 1, SUID; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; LOCUS COERULEUS; MALE; MICROINJECTIONS; MICROSCOPY, FLUORESCENCE; RATS; RATS, SPRAGUE-DAWLEY; SUPRACHIASMATIC NUCLEUS;

EID: 0034954686     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/89522     Document Type: Article

References (48)

1. Suprachiasmatic nucleus: The brain's circadian clock
2. Activation of ventrolateral preoptic neurons during sleep
3. Effect of SCN lesions on sleep in squirrel monkeys: Evidence for opponent processes in sleep-wake regulation
4. Simulation of daytime vigilance by the additive interaction of a homeostatic and a circadian process
5. Sleep cycle oscillation: Reciprocal discharge by two brainstem neuronal groups
6. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle
7. Effects of locus coeruleus activation on electroencephalographic activity in the neocortex and hippocampus
8. Pseudorabies virus infection of the rat central nervous system: Ultrastructural characterization of viral replication, transport, and pathogenesis
9. Characterization of transsynaptic tracing with central application of Pseudorabies virus
10. Use of Pseudorabies virus to delineate multisynaptic circuits in brain: Opportunities and limitations
11. Transneuronal labeling of a nociceptive pathway, the spino- (trigeminal-) parabrachio-amygdaloid, in the rat
12. Interconnected parallel circuits between rat nucleus accumbens and thalamus revealed by retrograde transynaptic transport of pseudorabies virus
13. The role of locus coeruleus in the regulation of cognitive performance
14. Locus coeruleus and regulation of behavioral flexibility and attention
15. Short-term memory, alertness and performance: A reappraisal of their relationship to body temperature
16. The brain nucleus locus coeruleus: Restricted afferent control of a broad efferent network
17. Afferent projections to the rat locus coeruleus demonstrated by retrograde and anterograde tracing with cholera-toxin B subunit and Phaseolus vulgaris leucoagglutinin
18. Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat
19. The dorsomedial hypothalamic nucleus revisited: 1998 Update
20. Ventromedial and dorsomedial hypothalamic syndromes in the weanling rat: Is the "center" concept really outmoded?
21. Different patterns of neuronal infection after intracerebral injection of two strains of pseudorabies virus
22. Transneuronal tracing of neural pathways controlling an abdominal muscle, rectus abdominus, in the ferret
23. Forebrain nuclei involved in autonomic control
24. Projections of the suprachiasmatic nuclei, subparaventricular zone and retrochiasmatic area in the golden hamster
25. The anatomical basis for the expression of circadian rhythms: The efferent projections of the suprachiasmatic nucleus
26. Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
27. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
28. Neurons containing hypocretin (orexin) project to multiple neuronal systems
29. Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
30. Strong hypocretin (orexin) innervation of the locus coeruleus activates noradrenergic cells
31. Hypocretin/orexin depolarizes and decreases potassium conductance in locus coeruleus neurons
32. Orexin A activates locus coeruleus cell firing and increases arousal in the rat
33. Twenty-four hour rhythms of norepinephrine and serotonin in nucleus suprachiasmaticus, raphe nuclei, and locus coeruleus in the rat
34. Nucleus locus ceruelus: New evidence of anatomical and physiological specificity
35. Enhancement of behavioral and electroencephalographic indices of waking following stimulation of noradrenergic B-receptors within the medial septal region of the basal forebrain
36. Synergistic sedative effects of noradrenergic a1 and b-receptor blockade in forebrain electroencephalographic and behavioral indices
37. Sleep and its disorders
38. Sleep deprivation in depression: What do we know, where do we go?
39. Memory retrieval enhancement by locus coeruleus stimulation: Evidence for mediation by beta-receptors
40. Raphe origin of serotonergic nerve terminating in the cerebral ventricles
41. Extensive projections from the midbrain periaqueductal gray to the caudal ventrolateral medulla: A retrograde and anterograde tracing study in the rat
42. Potent excitatory influence of prefrontal cortex activity on noradrenergic locus coeruleus neurons
43. Activation of locus coeruleus from nucleus paragigantocellularis: A new excitatory amino acid pathway in brain