Does cellular sex matter? Dimorphic transcriptional differences between female and male endothelial cells

Atherosclerosis

Volumn 240, Issue 1, 2015, Pages 61-72

  Lorenz, Mario ^a,d   Koschate, Janina ^a   Kaufmann, Katharina ^a   Kreye, Corinna ^b   Mertens, Michael ^a   Kuebler, Wolfgang M ^a   Baumann, Gert ^a   Gossing, Gabriele ^a   Marki, Alex ^a   Zakrzewicz, Andreas ^a   Miéville, Christian ^a,d   Benn, Andreas ^c   Horbelt, Daniel ^c   Wratil, Paul R ^a   Stangl, Karl ^a   Stangl, Verena ^a,d  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MILTENYI BIOTEC GMBH   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

Endothelial cells; Gender; Gene expression; HUVEC; Sex; Shear stress; Tube formation

Indexed keywords

BETA ACTIN; CD18 ANTIGEN; CD86 ANTIGEN; COLONY STIMULATING FACTOR 1; COMPLEMENT COMPONENT C1; COMPLEMENT COMPONENT C1Q; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; HEME OXYGENASE 1; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1 RECEPTOR TYPE II; MESSENGER RNA; NEUROLIGIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; REV PROTEIN; THROMBOSPONDIN 1; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN A; GENETIC MARKER;

ARTICLE; CELL VIABILITY; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; MALE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; SHEAR STRESS; SRY GENE; UMBILICAL VEIN ENDOTHELIAL CELL; ANGIOGENESIS; CELL CULTURE; CELL SURVIVAL; COMPARATIVE STUDY; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC MARKER; MECHANICAL STRESS; METABOLISM; PHYSIOLOGICAL STRESS; PROCEDURES; SEXUAL DEVELOPMENT; TIME;

CELL SURVIVAL; CELLS, CULTURED; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC MARKERS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; SEX CHARACTERISTICS; SEX FACTORS; STRESS, MECHANICAL; STRESS, PHYSIOLOGICAL; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 84924265262     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2015.02.018     Document Type: Article

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