메뉴 건너뛰기




Volumn 11, Issue 1, 2015, Pages

Tat-induced histopathological alterations mediate hippocampus-associated behavioural impairments in rats

Author keywords

Hippocampus; Histopathology; Morris water maze; Novel object recognition test; Tat protein Clade B

Indexed keywords

TRANSACTIVATOR PROTEIN; NERVE PROTEIN;

EID: 84924258168     PISSN: None     EISSN: 17449081     Source Type: Journal    
DOI: 10.1186/s12993-014-0047-3     Document Type: Article
Times cited : (23)

References (57)
  • 1
    • 77952089812 scopus 로고    scopus 로고
    • Clinical correlates of HIV-associated neurocognitive disorders in South Africa
    • Joska JA, Fincham DS, Stein DJ, Paul RH, Seedat S. Clinical correlates of HIV-associated neurocognitive disorders in South Africa. AIDS. 2010;14:371-8.
    • (2010) AIDS , vol.14 , pp. 371-378
    • Joska, J.A.1    Fincham, D.S.2    Stein, D.J.3    Paul, R.H.4    Seedat, S.5
  • 2
    • 79956336664 scopus 로고    scopus 로고
    • Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef
    • Breuer S, Schievink SI, Schulte A, Blankenfeldt W, Fackler OT, Geyer M. Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS One. 2011;6(5):e20033.
    • (2011) PLoS One , vol.6 , Issue.5
    • Breuer, S.1    Schievink, S.I.2    Schulte, A.3    Blankenfeldt, W.4    Fackler, O.T.5    Geyer, M.6
  • 3
    • 33745011334 scopus 로고    scopus 로고
    • Role of the pro-inflammatory cytokines TNF-α and IL-1β in HIV-associated dementia
    • Brabers NA, Nottet HS. Role of the pro-inflammatory cytokines TNF-α and IL-1β in HIV-associated dementia. Eur J Clin Invest. 2006;36:447-58.
    • (2006) Eur J Clin Invest , vol.36 , pp. 447-458
    • Brabers, N.A.1    Nottet, H.S.2
  • 4
    • 84909971466 scopus 로고    scopus 로고
    • HIV-associated neurocognitive disorders
    • Sanmarti M. HIV-associated neurocognitive disorders. J Mol Psychiatr. 2014;2:2.
    • (2014) J Mol Psychiatr , vol.2 , pp. 2
    • Sanmarti, M.1
  • 5
    • 84855897049 scopus 로고    scopus 로고
    • Expression of HIV-Tat protein is associated with learning and memory deficits in the mouse
    • Carey AN, Sypek EI, Singh HD, McLaughlin JP. Expression of HIV-Tat protein is associated with learning and memory deficits in the mouse. Behav Brain Res. 2012;229:48-56.
    • (2012) Behav Brain Res , vol.229 , pp. 48-56
    • Carey, A.N.1    Sypek, E.I.2    Singh, H.D.3    McLaughlin, J.P.4
  • 7
    • 0141632883 scopus 로고    scopus 로고
    • Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain
    • Bruce-Keller AJ, Chauhan A, Dimayuga FO, Gee J, Keller JN, Nath A. Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain. J Neurosci. 2003;23(23):8417-22.
    • (2003) J Neurosci , vol.23 , Issue.23 , pp. 8417-8422
    • Bruce-Keller, A.J.1    Chauhan, A.2    Dimayuga, F.O.3    Gee, J.4    Keller, J.N.5    Nath, A.6
  • 8
    • 0034837645 scopus 로고    scopus 로고
    • Detection of HIV-1 gene sequences in hippocampal neurons isolated from postmortem AIDS brains by laser capture microdissection
    • Torres-Muñoz J, Stockton P, Tacoronte N, Roberts B, Maronpot RR, Petito CK. Detection of HIV-1 gene sequences in hippocampal neurons isolated from postmortem AIDS brains by laser capture microdissection. J Neuropathol Exp Neurol. 2001;60(9):885-92.
    • (2001) J Neuropathol Exp Neurol , vol.60 , Issue.9 , pp. 885-892
    • Torres-Muñoz, J.1    Stockton, P.2    Tacoronte, N.3    Roberts, B.4    Maronpot, R.R.5    Petito, C.K.6
  • 9
    • 0032989672 scopus 로고    scopus 로고
    • Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis
    • Brack-Werner R. Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis. AIDS. 1999;13:1.
    • (1999) AIDS , vol.13 , pp. 1
    • Brack-Werner, R.1
  • 10
    • 0033546424 scopus 로고    scopus 로고
    • Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes
    • Nath A, Contant K, Chen P, Scott C, Major EO. Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. J Biol Chem. 1999;274:17098-102.
    • (1999) J Biol Chem , vol.274 , pp. 17098-17102
    • Nath, A.1    Contant, K.2    Chen, P.3    Scott, C.4    Major, E.O.5
  • 11
    • 0030962775 scopus 로고    scopus 로고
    • Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein
    • Cheng J, Nath A, Knudsen B, Hochman S, Geiger JD, Ma M, et al. Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein. Neuroscience. 1998;82:97-106.
    • (1998) Neuroscience , vol.82 , pp. 97-106
    • Cheng, J.1    Nath, A.2    Knudsen, B.3    Hochman, S.4    Geiger, J.D.5    Ma, M.6
  • 12
    • 33847099936 scopus 로고    scopus 로고
    • Astrocytes are active players in cerebral innate immunity
    • Farina C, Aloisi F, Meinl E. Astrocytes are active players in cerebral innate immunity. Trends Immunol. 2007;28(3):138-45.
    • (2007) Trends Immunol , vol.28 , Issue.3 , pp. 138-145
    • Farina, C.1    Aloisi, F.2    Meinl, E.3
  • 13
    • 84875941036 scopus 로고    scopus 로고
    • A cellular star atlas: using astrocytes from pluripotent stem cells for disease studies
    • Krencik R, Ullian EM. A cellular star atlas: using astrocytes from pluripotent stem cells for disease studies. Front Cell Neurosci. 2013;7:25.
    • (2013) Front Cell Neurosci , vol.7 , pp. 25
    • Krencik, R.1    Ullian, E.M.2
  • 14
    • 73149083473 scopus 로고    scopus 로고
    • Functions of Tat: the versatile protein of human immunodeficiency virus type 1
    • Romani B, Engelbrecht S, Glashoof RH. Functions of Tat: the versatile protein of human immunodeficiency virus type 1. J Gen Virol. 2010;91:1-12.
    • (2010) J Gen Virol , vol.91 , pp. 1-12
    • Romani, B.1    Engelbrecht, S.2    Glashoof, R.H.3
  • 15
    • 0030068995 scopus 로고    scopus 로고
    • Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic
    • Nath A, Psooy K, Martin C, Knudsen B, Magnuson DS, Haughey N, et al. Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic. J Virol. 1996;70(3):1475.
    • (1996) J Virol , vol.70 , Issue.3 , pp. 1475
    • Nath, A.1    Psooy, K.2    Martin, C.3    Knudsen, B.4    Magnuson, D.S.5    Haughey, N.6
  • 16
    • 34248567671 scopus 로고    scopus 로고
    • Preventing HIV-1 tat-induced neuronal apoptosis using antioxidant enzymes: Mechanistic and therapeutic implications
    • Agrawal L, Louboutin J, Strayer DS. Preventing HIV-1 tat-induced neuronal apoptosis using antioxidant enzymes: Mechanistic and therapeutic implications. Virology. 2007;363(2):462-72.
    • (2007) Virology , vol.363 , Issue.2 , pp. 462-472
    • Agrawal, L.1    Louboutin, J.2    Strayer, D.S.3
  • 17
    • 84865986486 scopus 로고    scopus 로고
    • Inhibition of HIV-1 tat-induced transactivation and apoptosis by the divalent metal chelators, fusaric acid and picolinic acid-implications for HIV-1 mediated dementia
    • Ramautar A, Mabandla M, Blackburn J, Daniels WMU. Inhibition of HIV-1 tat-induced transactivation and apoptosis by the divalent metal chelators, fusaric acid and picolinic acid-implications for HIV-1 mediated dementia. Neurosci Res. 2012;74(1):59-63.
    • (2012) Neurosci Res , vol.74 , Issue.1 , pp. 59-63
    • Ramautar, A.1    Mabandla, M.2    Blackburn, J.3    Daniels, W.M.U.4
  • 18
    • 84860889573 scopus 로고    scopus 로고
    • The novel object recognition memory: neurobiology, test procedure, and its modifications
    • Antunes M, Biala G. The novel object recognition memory: neurobiology, test procedure, and its modifications. Cogn Process. 2012;13(2):93-110.
    • (2012) Cogn Process , vol.13 , Issue.2 , pp. 93-110
    • Antunes, M.1    Biala, G.2
  • 19
    • 0015145985 scopus 로고
    • The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat
    • O' Keefe J, Dostrovsky J. The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. Brain Res. 1971;34(1):171-5.
    • (1971) Brain Res , vol.34 , Issue.1 , pp. 171-175
    • O' Keefe, J.1    Dostrovsky, J.2
  • 20
    • 84924229991 scopus 로고    scopus 로고
    • The novel object recognition test in rodents: which are the essential methodological aspects?
    • Moscardo E, Salvetti B, Becchi S, Bertini G, Fabene PF. The novel object recognition test in rodents: which are the essential methodological aspects? Measuring Behavior. 2012;2012:476.
    • (2012) Measuring Behavior , vol.2012 , pp. 476
    • Moscardo, E.1    Salvetti, B.2    Becchi, S.3    Bertini, G.4    Fabene, P.F.5
  • 21
    • 0033565292 scopus 로고    scopus 로고
    • Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the adult female rat
    • Tanapat P, Hastings NB, Reeves AJ, Gould E. Estrogen stimulates a transient increase in the number of new neurons in the dentate gyrus of the adult female rat. J Neurosci. 1999;19(14):5792-801.
    • (1999) J Neurosci , vol.19 , Issue.14 , pp. 5792-5801
    • Tanapat, P.1    Hastings, N.B.2    Reeves, A.J.3    Gould, E.4
  • 22
    • 0025617479 scopus 로고
    • Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons
    • Woolley CS, Gould E, Frankfurt M, McEwen BS. Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons. J Neurosci. 1990;10(12):4035-9.
    • (1990) J Neurosci , vol.10 , Issue.12 , pp. 4035-4039
    • Woolley, C.S.1    Gould, E.2    Frankfurt, M.3    McEwen, B.S.4
  • 23
    • 1942468697 scopus 로고    scopus 로고
    • Shifts in preferred learning strategy across the estrous cycle in young female rats
    • Korol DL, Malin EL, Borden KA, Busby RA, Couper-Leo JM. Shifts in preferred learning strategy across the estrous cycle in young female rats. Horm Behav. 2004;45:330-8.
    • (2004) Horm Behav , vol.45 , pp. 330-338
    • Korol, D.L.1    Malin, E.L.2    Borden, K.A.3    Busby, R.A.4    Couper-Leo, J.M.5
  • 24
    • 0003698235 scopus 로고    scopus 로고
    • The Rat Brain in Stereotaxic Coordinates: The New Coronal Set
    • 5. San Diego: Elsevier Academic Press;
    • Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates: The New Coronal Set. 5. San Diego: Elsevier Academic Press; 2005. p. 209.
    • (2005) , pp. 209
    • Paxinos, G.1    Watson, C.2
  • 25
    • 0034614528 scopus 로고    scopus 로고
    • Tat mediates apoptosis in vivo in the rat central nervous system
    • Gavriil ES, Cooney R, Weeks BS. Tat mediates apoptosis in vivo in the rat central nervous system. Biochem Biophys Res Commun. 2000;267(1):252-6.
    • (2000) Biochem Biophys Res Commun , vol.267 , Issue.1 , pp. 252-256
    • Gavriil, E.S.1    Cooney, R.2    Weeks, B.S.3
  • 26
    • 33846461062 scopus 로고    scopus 로고
    • Morris water maze: procedures for assessing spatial and related forms of learning and memory
    • Voorhees CV, Williams MT. Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nat Protoc. 2006;1(2):848-58.
    • (2006) Nat Protoc , vol.1 , Issue.2 , pp. 848-858
    • Voorhees, C.V.1    Williams, M.T.2
  • 27
    • 50849107620 scopus 로고    scopus 로고
    • Neonatal intrahippocampal injection of the HIV-1 proteins gp120 and Tat: differential effects on behavior and the relationship to stereological hippocampal measures
    • Fitting S, Booze RM, Mactutus CF. Neonatal intrahippocampal injection of the HIV-1 proteins gp120 and Tat: differential effects on behavior and the relationship to stereological hippocampal measures. Brain Res. 2008;1232:139-54.
    • (2008) Brain Res , vol.1232 , pp. 139-154
    • Fitting, S.1    Booze, R.M.2    Mactutus, C.F.3
  • 28
    • 39849106952 scopus 로고    scopus 로고
    • Differential long-term neurotoxicity of HIV-1 proteins in the rat hippocampal formation: a design-based stereological study
    • Fitting S, Booze RM, Hasselrot U, Mactutus CF. Differential long-term neurotoxicity of HIV-1 proteins in the rat hippocampal formation: a design-based stereological study. Hippocampus. 2008;18(2):135-47.
    • (2008) Hippocampus , vol.18 , Issue.2 , pp. 135-147
    • Fitting, S.1    Booze, R.M.2    Hasselrot, U.3    Mactutus, C.F.4
  • 29
    • 34548208844 scopus 로고    scopus 로고
    • The prevalence and incidence of neurocognitive impairment in the HAART era
    • Robertson KR, Smurzynski M, Parsons TD, Wu K, Bosch RJ, Wu J, et al. The prevalence and incidence of neurocognitive impairment in the HAART era. AIDS. 2007;21:1915-21.
    • (2007) AIDS , vol.21 , pp. 1915-1921
    • Robertson, K.R.1    Smurzynski, M.2    Parsons, T.D.3    Wu, K.4    Bosch, R.J.5    Wu, J.6
  • 30
    • 1642423921 scopus 로고    scopus 로고
    • Role of hippocampal CA3 μ-opoid receptors in spatial learning and memory
    • Meilandt WJ, Barea-Rodriguez E, Harvey SAK, Martinez Jr JL. Role of hippocampal CA3 μ-opoid receptors in spatial learning and memory. J Neurosci. 2004;24(12):2953-62.
    • (2004) J Neurosci , vol.24 , Issue.12 , pp. 2953-2962
    • Meilandt, W.J.1    Barea-Rodriguez, E.2    Harvey, S.A.K.3    Martinez, J.L.4
  • 31
    • 84873667458 scopus 로고    scopus 로고
    • Synaptic dysfunction in the hippocampus accompanies a learning and memory deficits in HIV-1 Tat transgenic mice
    • Fitting S, Ignatowska-Jankowska BM, Bull C, Skoff RP, Lichtman AH, Wise LE, et al. Synaptic dysfunction in the hippocampus accompanies a learning and memory deficits in HIV-1 Tat transgenic mice. Biol Psychiatry. 2013;73(5):443-53.
    • (2013) Biol Psychiatry , vol.73 , Issue.5 , pp. 443-453
    • Fitting, S.1    Ignatowska-Jankowska, B.M.2    Bull, C.3    Skoff, R.P.4    Lichtman, A.H.5    Wise, L.E.6
  • 32
    • 0028434810 scopus 로고
    • Retrograde amnesia and memory activation in rats with ibotenate injections to the hippocampus or subiculum
    • Bolhuis J, Stewart CA, Forest EM. Retrograde amnesia and memory activation in rats with ibotenate injections to the hippocampus or subiculum. Q J Exp Psychol. 1994;47:129-50.
    • (1994) Q J Exp Psychol , vol.47 , pp. 129-150
    • Bolhuis, J.1    Stewart, C.A.2    Forest, E.M.3
  • 34
    • 13844275885 scopus 로고    scopus 로고
    • Retrograde amnesia: neither partial nor complete hippocampal injections in rats result in preferential sparing of remote spatial memory, even after reminding
    • Martin SJ, de Hoz L, Morris RG. Retrograde amnesia: neither partial nor complete hippocampal injections in rats result in preferential sparing of remote spatial memory, even after reminding. Neuropsychologia. 2005;43:609-24.
    • (2005) Neuropsychologia , vol.43 , pp. 609-624
    • Martin, S.J.1    Hoz, L.2    Morris, R.G.3
  • 35
    • 34250853446 scopus 로고    scopus 로고
    • The hippocampus and spatial memory: findings with a novel modification of the water maze
    • Clark RE, Broadbent NJ, Squire LR. The hippocampus and spatial memory: findings with a novel modification of the water maze. J Neurosci. 2007;27(25):6647-54.
    • (2007) J Neurosci , vol.27 , Issue.25 , pp. 6647-6654
    • Clark, R.E.1    Broadbent, N.J.2    Squire, L.R.3
  • 36
    • 0027214025 scopus 로고
    • Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze
    • Gallagher M, Burwell R, Burchinal M. Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze. Behav Neurosci. 1993;107(4):618-26.
    • (1993) Behav Neurosci , vol.107 , Issue.4 , pp. 618-626
    • Gallagher, M.1    Burwell, R.2    Burchinal, M.3
  • 37
    • 77950691905 scopus 로고    scopus 로고
    • Spatial learning of the water maze: progression of brain circuits mapped with cytochrome oxidase histochemistry
    • Conejo NM, González-Pardo H, Gonzalez-Lima F, Arias JL. Spatial learning of the water maze: progression of brain circuits mapped with cytochrome oxidase histochemistry. Neurobiol Learn Mem. 2010;93(3):362-71.
    • (2010) Neurobiol Learn Mem , vol.93 , Issue.3 , pp. 362-371
    • Conejo, N.M.1    González-Pardo, H.2    Gonzalez-Lima, F.3    Arias, J.L.4
  • 38
    • 80355145729 scopus 로고    scopus 로고
    • Morris water maze test for learning and memory deficits in Alzheimer's disease model mice
    • Bromley-Brits K, Deng Y, Song W. Morris water maze test for learning and memory deficits in Alzheimer's disease model mice. J Vis Exp. 2011;53:e2920.
    • (2011) J Vis Exp , vol.53
    • Bromley-Brits, K.1    Deng, Y.2    Song, W.3
  • 39
    • 84870256885 scopus 로고    scopus 로고
    • Behavioral phenotypic properties of a natural occurring rat model of congenital stationary night blindness with Cacna1f mutation
    • An J, Wang L, Guo Q, Li L, Xia F, Zhang Z. Behavioral phenotypic properties of a natural occurring rat model of congenital stationary night blindness with Cacna1f mutation. J Neurogenet. 2012;26(3-4):363-73.
    • (2012) J Neurogenet , vol.26 , Issue.3-4 , pp. 363-373
    • An, J.1    Wang, L.2    Guo, Q.3    Li, L.4    Xia, F.5    Zhang, Z.6
  • 40
    • 84899140299 scopus 로고    scopus 로고
    • Astrocytic expression of HIV-1 viral protein R in the hippocampus causes chromatolysis, synaptic loss and memory impairment
    • Torres L, Noel RJ. Astrocytic expression of HIV-1 viral protein R in the hippocampus causes chromatolysis, synaptic loss and memory impairment. J Neuroinflammation. 2014;11:53.
    • (2014) J Neuroinflammation , vol.11 , pp. 53
    • Torres, L.1    Noel, R.J.2
  • 41
    • 77954317073 scopus 로고    scopus 로고
    • One-trial object recognition in rats and mice: methodological and theoretical issues
    • Ennaceur A. One-trial object recognition in rats and mice: methodological and theoretical issues. Behav Brain Res. 2010;215:244-54.
    • (2010) Behav Brain Res , vol.215 , pp. 244-254
    • Ennaceur, A.1
  • 43
    • 13244258435 scopus 로고    scopus 로고
    • Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation
    • Bennett EJ, Bence NF, Jayakumar R, Kopito RR. Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation. Mol Cell. 2005;17:351-65.
    • (2005) Mol Cell , vol.17 , pp. 351-365
    • Bennett, E.J.1    Bence, N.F.2    Jayakumar, R.3    Kopito, R.R.4
  • 44
    • 0033134869 scopus 로고    scopus 로고
    • Aggregates in neurodegenerative disease: crowds and power?
    • Tran PB, Miller RJ. Aggregates in neurodegenerative disease: crowds and power? Trends Neurosci. 1999;22(5):194-7.
    • (1999) Trends Neurosci , vol.22 , Issue.5 , pp. 194-197
    • Tran, P.B.1    Miller, R.J.2
  • 45
    • 0037077040 scopus 로고    scopus 로고
    • Toxic proteins in neurodegenerative disease
    • Taylor JP, Hardy J, Fischbeck KH. Toxic proteins in neurodegenerative disease. Science. 2002;296(5575):1991-5.
    • (2002) Science , vol.296 , Issue.5575 , pp. 1991-1995
    • Taylor, J.P.1    Hardy, J.2    Fischbeck, K.H.3
  • 47
    • 84897094564 scopus 로고    scopus 로고
    • Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
    • Hetz C, Mollereau B. Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases. Nat Rev Neurosci. 2014;15(4):233-49.
    • (2014) Nat Rev Neurosci , vol.15 , Issue.4 , pp. 233-249
    • Hetz, C.1    Mollereau, B.2
  • 48
    • 0028399655 scopus 로고
    • Astrocytes: form, functions and roles in disease
    • Montgomery DL. Astrocytes: form, functions and roles in disease. Vet Pathol. 1994;31:145-67.
    • (1994) Vet Pathol , vol.31 , pp. 145-167
    • Montgomery, D.L.1
  • 50
    • 26044438460 scopus 로고    scopus 로고
    • Actions of TNF-α on glutamatergic synaptic transmission in the central nervous system
    • Pickering M, Cumiskey D, O'Connor JJ. Actions of TNF-α on glutamatergic synaptic transmission in the central nervous system. Exp Physiol. 2005;90(5):663-70.
    • (2005) Exp Physiol , vol.90 , Issue.5 , pp. 663-670
    • Pickering, M.1    Cumiskey, D.2    O'Connor, J.J.3
  • 51
    • 0031201923 scopus 로고    scopus 로고
    • TNF-alpha opens a paracellular route for HIV-1 invasion across the blood-brain barrier
    • Fiala M, Looney DJ, Stins M, Way DD, Zhang L, Gan XIAOHU, et al. TNF-alpha opens a paracellular route for HIV-1 invasion across the blood-brain barrier. Mol Med. 1997;3(8):553.
    • (1997) Mol Med , vol.3 , Issue.8 , pp. 553
    • Fiala, M.1    Looney, D.J.2    Stins, M.3    Way, D.D.4    Zhang, L.5    Gan, X.6
  • 52
    • 84882715575 scopus 로고    scopus 로고
    • The spatial relationship between neurons and astrocytes in HIV-associated dementia
    • Roberts ES, Chana G, Nguyen TB, Perera G, Landau S, Rbe-Hesketh S, et al. The spatial relationship between neurons and astrocytes in HIV-associated dementia. J Neurovirol. 2012;19(2):123-30.
    • (2012) J Neurovirol , vol.19 , Issue.2 , pp. 123-130
    • Roberts, E.S.1    Chana, G.2    Nguyen, T.B.3    Perera, G.4    Landau, S.5    Rbe-Hesketh, S.6
  • 53
    • 33745869784 scopus 로고    scopus 로고
    • Mechanisms of neuronal injury and death in HIV-1 associated dementia
    • Kaul M, Lipton SA. Mechanisms of neuronal injury and death in HIV-1 associated dementia. Curr HIV Res. 2006;4:307-18.
    • (2006) Curr HIV Res , vol.4 , pp. 307-318
    • Kaul, M.1    Lipton, S.A.2
  • 55
    • 0026709499 scopus 로고
    • Human immunodeficiency virus type 1-infected monocytic cells can destroy human neural cells after cell-to-cell adhesion
    • Tardieu M, Hery C, Peudenier S, Boespflug O, Montagnier L. Human immunodeficiency virus type 1-infected monocytic cells can destroy human neural cells after cell-to-cell adhesion. Ann Neurol. 1992;32:11-7.
    • (1992) Ann Neurol , vol.32 , pp. 11-17
    • Tardieu, M.1    Hery, C.2    Peudenier, S.3    Boespflug, O.4    Montagnier, L.5
  • 56
    • 67649537643 scopus 로고    scopus 로고
    • What does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine?
    • Campbell GR, Loret EP. What does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine? Retrovirology. 2009;6:50.
    • (2009) Retrovirology , vol.6 , pp. 50
    • Campbell, G.R.1    Loret, E.P.2
  • 57
    • 84884862089 scopus 로고    scopus 로고
    • The effects of HIV-Tat DNA on regulating the immune response of HIV DNA vaccine in mice
    • Liu Y, Fusheng L, Qi Z, Hao Y, Hong K, Liu Y, et al. The effects of HIV-Tat DNA on regulating the immune response of HIV DNA vaccine in mice. Virol J. 2013;10:297.
    • (2013) Virol J , vol.10 , pp. 297
    • Liu, Y.1    Fusheng, L.2    Qi, Z.3    Hao, Y.4    Hong, K.5    Liu, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.