Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 tat transgenic mice

Biological Psychiatry

Volumn 73, Issue 5, 2013, Pages 443-453

  Fitting, Sylvia ^a   Ignatowska Jankowska, Bogna M ^a   Bull, Cecilia ^a   Skoff, Robert P ^b   Lichtman, Aron H ^a   Wise, Laura E ^a   Fox, Michael A ^a   Su, Jianmin ^a   Medina, Alexandre E ^a   Krahe, Thomas E ^a   Knapp, Pamela E ^a   Guido, William ^a   Hauser, Kurt F ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Electron microscopy; fear conditioning; gephyrin; hippocampal area CA1; long term potentiation; Morris water maze; NeuroAIDS; neuroplasticity; spatial learning; synaptotagmin

Indexed keywords

GEPHYRIN; GLIAL FIBRILLARY ACIDIC PROTEIN; SYNAPTOTAGMIN II; TRANSACTIVATOR PROTEIN;

AMNESIA; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CELL DEATH; CELL VACUOLE; CONDITIONING; CYTOPLASM; DENDRITIC SPINE; ELECTROPHYSIOLOGY; FEAR; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; LAMELLAR BODY; LEARNING DISORDER; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SYNAPTIC POTENTIAL; TRANSGENIC MOUSE;

ANIMALS; ASTROCYTES; BEHAVIOR, ANIMAL; CELL DEATH; CONDITIONING, CLASSICAL; DENDRITES; FEAR; GENE PRODUCTS, TAT; HIPPOCAMPUS; HIV-1; LEARNING; MAZE LEARNING; MEMORY; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; NEURONS; SYNAPSES;

EID: 84873667458     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.09.026     Document Type: Article

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