Alternative pathways of osteoclastogenesis in inflammatory arthritis

Nature Reviews Rheumatology

Volumn 11, Issue 3, 2015, Pages 189-194

  Adamopoulos, Iannis E ^a   Mellins, Elizabeth D ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD135 ANTIGEN; COLONY STIMULATING FACTOR 1; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 24; INTERLEUKIN 27; INTERLEUKIN 33; INTERLEUKIN 4; INTERLEUKIN 6; OSTEOCLAST DIFFERENTIATION FACTOR; PLACENTAL GROWTH FACTOR; SCATTER FACTOR; TUMOR NECROSIS FACTOR; VASCULOTROPIN;

BONE DESTRUCTION; BONE MARROW CELL; BONE REMODELING; CELL DIFFERENTIATION; CELL FUNCTION; CELL POPULATION; DENDRITIC CELL; HUMAN; INFLAMMATION; INFLAMMATORY CELL; MACROPHAGE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; ANIMAL; ARTHRITIS; OSTEOLYSIS; PATHOLOGY;

ANIMALS; ARTHRITIS; BONE RESORPTION; HUMANS; INFLAMMATION; OSTEOCLASTS;

EID: 84924160797     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2014.198     Document Type: Review

References (61)

1. McQueen, F. M., et al. Magnetic resonance imaging of the wrist in early rheumatoid arthritis reveals a high prevalence of erosions at four months after symptom onset. Ann. Rheum. Dis. 57, 350-356 (1998
2. Kane, D., Stafford, L., Bresnihan, B. & FitzGerald, O. A prospective, clinical and radiological study of early psoriatic arthritis: an early synovitis clinic experience. Rheumatology (Oxford) 42, 1460-1468 (2003
3. Magni-Manzoni, S., Malattia, C., Lanni, S. & Ravelli, A. Advances and challenges in imaging in juvenile idiopathic arthritis. Nat. Rev. Rheumatol. 8, 329-336 (2012
4. Teitelbaum, S. L. & Ross, F. P. Genetic regulation of osteoclast development and function. Nat. Rev. Genet. 4, 638-649 (2003
5. Nombela-Arrieta, C., Ritz, J. & Silberstein, L. E. The elusive nature and function of mesenchymal stem cells. Nat. Rev. Mol. Cell Biol. 12, 126-131 (2011
6. Walsh, M. C., et al. Osteoimmunology: interplay between the immune system and bone metabolism. Annu. Rev. Immunol. 24, 33-63 (2006
7. Xiong, J., et al. Matrix-embedded cells control osteoclast formation. Nat. Med. 17, 1235-1241 (2011
8. Karsenty, G. Transcriptional control of skeletogenesis. Annu. Rev. Genomics Hum. Genet. 9, 183-196 (2008
9. So, H., et al. Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-Associated receptor gene expression. J. Biol. Chem. 278, 24209-24216 (2003
10. Kim, Y., et al. Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-Associated receptor but not triggering receptor expressed by myeloid cells 2 during osteoclastogenesis. J. Biol. Chem. 280, 32905-32913 (2005
11. Andersen, M., et al. Synovial explant inflammatory mediator production corresponds to rheumatoid arthritis imaging hallmarks: a cross sectional study. Arthritis Res. Ther. 16, R107 (2014
12. Gautier, E. L., et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat. Immunol. 13, 1118-1128 (2012
13. Bendall, S. C., et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science 332, 687-696 (2011
14. Gordon, S. & Martinez, F. O. Alternative activation of macrophages: mechanism and functions. Immunity 32, 593-604 (2010
15. Ji, J. D., et al. Inhibition of RANK expression and osteoclastogenesis by TLRs and IFN γ in human osteoclast precursors. J. Immunol. 183, 7223-7233 (2009
16. Joyce-Shaikh, B., et al. Myeloid DAP12-Associating lectin (MDL) 1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis. J. Exp. Med. 207, 579-589 (2010
17. Koga, T., et al. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 428, 758-763 (2004
18. Kim, N., Takami, M., Rho, J., Josien, R. & Choi, Y. A novel member of the leukocyte receptor complex regulates osteoclast differentiation. J. Exp. Med. 195, 201-209 (2002
19. Alnaeeli, M., Penninger, J. M. & Teng, Y. T. A. Immune interactions with CD4+ T cells promote the development of functional osteoclasts from murine CD11c+ dendritic cells. J. Immunol. 177, 3314-3326 (2006
20. Wakkach, A., et al. Bone marrow microenvironment controls the in vivo differentiation of murine dendritic cells into osteoclasts. Blood 112, 5074-5083 (2008
21. Rivollier, A., et al. Immature dendritic cell transdifferentiation into osteoclasts: a novel pathway sustained by the rheumatoid arthritis microenvironment. Blood 104, 4029-4037 (2004
22. Tucci, M., et al. Immature dendritic cells in multiple myeloma are prone to osteoclast-like differentiation through interleukin 17A stimulation. Br. J. Haematol. 161, 821-831 (2013
23. Mensah, K. A., et al. Mediation of nonerosive arthritis in a mouse model of lupus by interferon α stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis. Arthritis Rheum. 62, 1127-1137 (2010
24. Jacome-Galarza, C. E., Lee, S. K., Lorenzo, J. A. & Aguila, H. L. Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery. J. Bone Miner. Res. 28, 1203-1213 (2013
25. Yoshida, H., et al. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 345, 442-444 (1990
26. MacDonald, K. P., et al. The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion. J. Immunol. 175, 1399-1405 (2005
27. Niida, S., et al. Vascular endothelial growth factor can substitute for macrophage colony-stimulating factor in the support of osteoclastic bone resorption. J. Exp. Med. 190, 293-298 (1999
28. Lean, J. M., Fuller, K. & Chambers, T. J. FLT3 ligand can substitute for macrophage colony-stimulating factor in support of osteoclast differentiation and function. Blood 98, 2707-2713 (2001
29. Adamopoulos, I. E., Xia, Z., Lau, Y. S. & Athanasou, N. A. Hepatocyte growth factor can substitute for M CSF to support osteoclastogenesis. Biochem. Biophys. Res. Commun. 350, 478-483 (2006
30. Wei, S., et al. Functional overlap but differential expression of CSF 1 and IL 34 in their CSF 1 receptor-mediated regulation of myeloid cells. J. Leukoc. Biol. 88, 495-505 (2010
31. Lee, M. S., et al. GM CSF regulates fusion of mononuclear osteoclasts into bone-resorbing osteoclasts by activating the Ras/ERK pathway. J. Immunol. 183, 3390-3399 (2009
32. Chiu, Y. H., et al. Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC STAMP). J. Bone Miner. Res. 27, 79-92 (2012
33. Lari, R., et al Macrophage Lineage Phenotypes and Osteoclastogenesis-complexity in the Control by GM CSF and TGF β. Bone 40, 323-336 (2007
34. Lacey, D. C., et al. Defining GM CSF and macrophage CSF dependent macrophage responses by in vitro models. J. Immunol. 188, 5752-5765 (2012
35. Hiasa, M., et al. GM CSF and IL 4 induce dendritic cell differentiation and disrupt osteoclastogenesis through M CSF receptor shedding by up-regulation of TNF α converting enzyme (TACE). Blood 114, 4517-4526 (2009
36. Nomura, K., Kuroda, S., Yoshikawa, H. & Tomita, T. Inflammatory osteoclastogenesis can be induced by GM CSF and activated under TNF immunity. Biochem. Biophys. Res. Commun. 367, 881-887 (2008
37. Taylor, R. M., Kashima, T. G., Knowles, H. J. & Athanasou, N. A. VEGF, FLT3 ligand, PlGF and HGF can substitute for M CSF to induce human osteoclast formation: implications for giant cell tumour pathobiology. Lab. Invest. 92, 1398-1406 (2012
38. Wang, Y., et al. IL 34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. Nat. Immunol. 13, 753-760 (2012
39. Chen, Z., Buki, K., Vaaraniemi, J., Gu, G. & Vaananen, H. K. The critical role of IL 34 in osteoclastogenesis. PLoS ONE 6, e18689 (2011
40. Gravallese, E. M., et al. Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis. Am. J. Pathol. 152, 943-951 (1998
41. Sato, K., et al. TH17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med. 203, 2673-2682 (2006
42. Pettit, A. R., et al. TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am. J. Pathol. 159, 1689-1699 (2001
43. Sinningen, K., et al. Skeletal and extraskeletal actions of denosumab. Endocrine 42, 52-62 (2012
44. Li, J., et al. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc. Natl Acad. Sci. USA 97, 1566-1571 (2000
45. Kobayashi, K., et al. Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J. Exp. Med. 191, 275-286 (2000
46. Kim, N., et al. Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis. J. Exp. Med. 202, 589-595 (2005
47. Kadono, Y., et al. Strength of TRAF6 signalling determines osteoclastogenesis. EMBO Rep. 6, 171-176 (2005
48. Wei, S., Kitaura, H., Zhou, P., Ross, F. P. & Teitelbaum, S. L. IL 1 mediates TNF-induced osteoclastogenesis. J. Clin. Invest. 115, 282-290 (2005
49. Kim, J. H., et al. The mechanism of osteoclast differentiation induced by IL 1. J. Immunol. 183, 1862-1870 (2009
50. Yarilina, A., Xu, K., Chen, J. & Ivashkiv, L. B. TNF activates calcium-nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages. Proc. Natl Acad. Sci. USA 108, 1573-1578 (2011
51. Adamopoulos, I. E., et al. IL 23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass. J. Immunol. 187, 951-959 (2011
52. Adamopoulos, I. E., et al. Interleukin 17A upregulates receptor activator of NF ?B on osteoclast precursors. Arthritis Res. Ther. 12, R29 (2010
53. Yokota, K., et al. Combination of tumor necrosis factor α and interleukin 6 induces mouse osteoclast-like cells with bone resorption activity both in vitro and in vivo. Arthritis Rheumatol. 66, 121-129 (2014
54. Axmann, R., et al. Inhibition of interleukin 6 receptor directly blocks osteoclast formation in vitro and in vivo. Arthritis Rheum. 60, 2747-2756 (2009
55. Steeve, K. T., Marc, P., Sandrine, T., Dominique, H. & Yannick, F. IL 6, RANKL, TNF α/IL 1: interrelations in bone resorption pathophysiology. Cytokine Growth Factor Rev. 15, 49-60 (2004
56. Adamopoulos, I. E. & Pflanz, S. The emerging role of interleukin 27 in inflammatory arthritis and bone destruction. Cytokine Growth Factor Rev. 24, 115-121 (2013
57. Zaiss, M. M., et al. IL 33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF α mediated bone loss. J. Immunol. 186, 6097-6105 (2011
58. Charles, J. F., et al. Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. J. Clin. Invest. 122, 4592-4605 (2012
59. Xue, J., et al. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity 40, 274-288 (2014
60. Amara, K., et al. Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition. J. Exp. Med. 210, 445-455 (2013
61. Harre, U., et al. Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. J. Clin. Invest. 122, 1791-1802 (2012