Mitochondrial lysates induce inflammation and alzheimer's disease-relevant changes in microglial and neuronal cells

Journal of Alzheimer's Disease

Volumn 45, Issue 1, 2015, Pages 305-318

  Wilkins, Heather M ^a,b   Carl, Steven M ^b   Weber, Sam G ^b   Ramanujan, Suruchi A ^b   Festoff, Barry W ^a,c   Linseman, Daniel A ^d   Swerdlow, Russell H ^a,b  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^c pHLOGISTIX Neurodiagnostics   (United States)

^d UNIVERSITY OF DENVER   (United States)

Author keywords

Alzheimer's disease; amyloid protein precursor; inflammation; mitochondria; mtDNA; TREM2

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CELL NUCLEUS DNA; DAMAGE ASSOCIATED MOLECULAR PATTERN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MEMBRANE RECEPTOR; MESSENGER RNA; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUTROPHIL COLLAGENASE; PYROXYLIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; TREM2 PROTEIN, HUMAN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL LYSATE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; CYTOSOL; MICROGLIA; MITOCHONDRIAL LYSATE; MITOCHONDRION; MITOPHAGY; MOUSE; NERVE CELL; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WHOLE CELL; ANIMAL; CELL FRACTIONATION; CELL LINE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; NEUROBLASTOMA; PATHOLOGY; ULTRASTRUCTURE;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE; CYTOKINES; DNA, MITOCHONDRIAL; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MICROGLIA; MITOCHONDRIA; NEUROBLASTOMA; NEURONS; NF-KAPPA B; RECEPTORS, IMMUNOLOGIC; RNA, MESSENGER; SUBCELLULAR FRACTIONS;

EID: 84924099385     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-142334     Document Type: Article

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