-
1
-
-
1842631484
-
Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells
-
Wolint P, Betts MR, Koup RA, Oxenius A. Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cells. J Exp Med. 2004; 199: 92-936. doi: 10.1084/jem. 20031799
-
(2004)
J Exp Med.
, vol.199
, pp. 92-936
-
-
Wolint, P.1
Betts, M.R.2
Koup, R.A.3
Oxenius, A.4
-
2
-
-
22144437688
-
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
-
PMID: 15980149
-
Klebanoff CA, Gattinoni L, Torabi-Parizi P, Kerstann K, Cardones AR, Finkelstein SE, et al. Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells. Proc Natl Acad Sci U S A. 2005; 102: 9571-9576. doi: 10.1073/pnas.0503726102 PMID: 15980149
-
(2005)
Proc Natl Acad Sci USA.
, vol.102
, pp. 9571-9576
-
-
Klebanoff, C.A.1
Gattinoni, L.2
Torabi-Parizi, P.3
Kerstann, K.4
Cardones, A.R.5
Finkelstein, S.E.6
-
3
-
-
84868255419
-
Sorting through subsets which T-cell populations mediate highly effective adoptive immunotherapy
-
PMID 23090074
-
Klebanoff CA, Gattinoni L, Restifo NP. Sorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy? J Immunother. 2012; 35: 651-660. doi: 10.1097/CJI. 0b013e31827806e6 PMID: 23090074
-
(2012)
J Immunother.
, vol.35
, pp. 651-660
-
-
Klebanoff, C.A.1
Gattinoni, L.2
Restifo, N.P.3
-
4
-
-
84865808327
-
The stoichiometric production of IL-2 and IFN- mRNA defines memory T cells that can self-renew after adoptive transfer in humans
-
Wang A, Chandran S, Shah SA, Chiu Y, Paria BC, Aghamolla T, et al. The stoichiometric production of IL-2 and IFN-? mRNA defines memory T cells that can self-renew after adoptive transfer in humans. Sci Transl Med. 2012, doi: 10.1126/scitranslmed.3004306
-
(2012)
Sci Transl Med.
-
-
Wang, A.1
Chandran, S.2
Shah, S.A.3
Chiu, Y.4
Paria, B.C.5
Aghamolla, T.6
-
5
-
-
79955531127
-
In vitro generated anti-tumor T lymphocytes exhibit distinct subsets mimicking in vivo antigen-experienced cells
-
PMID: 21305379
-
Yang S, Gattinoni L, Liu F, Ji Y, Yu Z, Restifo NP, et al. In vitro generated anti-tumor T lymphocytes exhibit distinct subsets mimicking in vivo antigen-experienced cells. Cancer Immunol Immunother. 2011; 60: 739-746. doi: 10.1007/s00262-011-0977-7 PMID: 21305379
-
(2011)
Cancer Immunol Immunother.
, vol.60
, pp. 739-746
-
-
Yang, S.1
Gattinoni, L.2
Liu, F.3
Ji, Y.4
Yu, Z.5
Restifo, N.P.6
-
6
-
-
84858758766
-
Adoptive immunotherapy for cancer: Harnessing the T cell response
-
PMID: 22437939
-
Restifo NP, Dudley ME, Rosenberg SA. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol. 2012; 12: 269-281. doi: 10.1038/nri3191 PMID: 22437939
-
(2012)
Nat Rev Immunol.
, vol.12
, pp. 269-281
-
-
Restifo, N.P.1
Dudley, M.E.2
Rosenberg, S.A.3
-
7
-
-
20244366111
-
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
-
PMID 15800326
-
Dudley ME, Wunderlich JR, Yang JC, Sherry RM, Topalian SL, Restifo NP, et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol. 2005; 23: 2346-2357. doi: 10.1200/JCO.2005.00. 240 PMID: 15800326
-
(2005)
J Clin Oncol.
, vol.23
, pp. 2346-2357
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Yang, J.C.3
Sherry, R.M.4
Topalian, S.L.5
Restifo, N.P.6
-
8
-
-
4344671644
-
Effector function of human tumor-specific CD8 T cells in melanoma lesions: A state of local functional tolerance
-
PMID: 15087405
-
Zippelius A, Batard P, Rubio-Godoy V, Bioley G, Liénard D, Lejeune F, et al. Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res. 2004; 64: 2865-2873. doi: 10.1158/0008-5472.CAN-03-3066 PMID: 15087405
-
(2004)
Cancer Res.
, vol.64
, pp. 2865-2873
-
-
Zippelius, A.1
Batard, P.2
Rubio-Godoy, V.3
Bioley, G.4
Liénard, D.5
Lejeune, F.6
-
9
-
-
84855573739
-
The roles of tumor-derived exosomes in cancer pathogenesis
-
PMID: 22190973
-
Yang C, Robbins PD. The Roles of Tumor-Derived Exosomes in Cancer Pathogenesis. Clin Dev Immunol. 2011; 2011: 842849. doi: 10.1155/2011/842849 PMID: 22190973
-
(2011)
Clin Dev Immunol.
, vol.2011
, pp. 842849
-
-
Yang, C.1
Robbins, P.D.2
-
10
-
-
78349245955
-
Tumor antigen cross-presentation and the dendritic cell: Where it all begins?
-
PMID: 20976125
-
McDonnell AM, Robinson BWS, Currie AJ. Tumor Antigen Cross-Presentation and the Dendritic Cell: Where it All Begins? Clin Dev Immunol. 2010; 2010:539519. doi: 10.1155/2010/539519 PMID: 20976125
-
(2010)
Clin Dev Immunol.
, vol.2010
, pp. 539519
-
-
McDonnell, A.M.1
Robinson, B.W.S.2
Currie, A.J.3
-
11
-
-
41349083781
-
Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses
-
PMID: 18003887
-
Kenna TJ, Thomas R, Steptoe RJ. Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses. Blood. 2008; 111: 2091-2100. doi: 10.1182/blood-2007-07-103200 PMID: 18003887
-
(2008)
Blood.
, vol.111
, pp. 2091-2100
-
-
Kenna, T.J.1
Thomas, R.2
Steptoe, R.J.3
-
12
-
-
76249092898
-
Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function
-
PMID: 19995901
-
Kenna TJ, Waldie T, McNally A, Thomson M, Yagita H, Thomas R, et al. Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function. Journal of Immunology. 2010; 184: 598-606. doi: 10.4049/jimmunol.0900032 PMID: 19995901
-
(2010)
Journal of Immunology.
, vol.184
, pp. 598-606
-
-
Kenna, T.J.1
Waldie, T.2
McNally, A.3
Thomson, M.4
Yagita, H.5
Thomas, R.6
-
13
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
PMID: 22437870
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nature Reviews Cancer. 2012; 12: 252-264. doi: 10.1038/nrc3239 PMID: 22437870
-
(2012)
Nature Reviews Cancer.
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
14
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
PMID: 17304234
-
Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat Immunol. 2007; 8: 239-245. doi: 10.1038/ni1443 PMID: 17304234
-
(2007)
Nat Immunol.
, vol.8
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
15
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
PMID: 18173375
-
Keir ME, Butte MJ, Freeman GJ, Sharpe AH. PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol. 2008; 26: 677-704. doi: 10.1146/annurev.immunol.26.021607.090331 PMID: 18173375
-
(2008)
Annu Rev Immunol.
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
16
-
-
32544459770
-
Restoring function in exhausted CD8+ T cells during chronic viral infection
-
PMID: 16382236
-
Barber DL, Wherry EJ, Masupost D, Zhu B, Allison JP, Sharpe AH, et al. Restoring function in exhausted CD8+ T cells during chronic viral infection. Nature. 2006; 439: 682-687. doi: 10.1038/ nature04444 PMID: 16382236
-
(2006)
Nature.
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masupost, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
-
17
-
-
34347371572
-
Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy
-
PMID: 17289811
-
Tsushima F, Yao S, Shin T, Flies A, Flies S, Xu H, et al. Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy. Blood. 2007; 110: 180-185. doi: 10.1182/blood-2006-11-060087 PMID: 17289811
-
(2007)
Blood.
, vol.110
, pp. 180-185
-
-
Tsushima, F.1
Yao, S.2
Shin, T.3
Flies, A.4
Flies, S.5
Xu, H.6
-
18
-
-
34347389213
-
Role of PD-1 and its ligand B7-H1, in early fate decisions of CD8 T cells
-
PMID: 17392506
-
Goldberg MV, Maris CH, Hipkiss EL, Flies AS, Zhen L, Tuder RM, et al. Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood. 2007; 110: 186-192. doi: 10.1182/blood-2006-12-062422 PMID: 17392506
-
(2007)
Blood
, vol.110
, pp. 186-192
-
-
Goldberg, M.V.1
Maris, C.H.2
Hipkiss, E.L.3
Flies, A.S.4
Zhen, L.5
Tuder, R.M.6
-
19
-
-
0842325739
-
PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells
-
PMID: 14871849
-
Blank C, Brown I, Peterson AC, Spiotto M, Iwai Y, Honjo T, et al. PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Res. 2004; 64: 1140-1145. doi: 10.1158/0008-5472.CAN-03-3259 PMID: 14871849
-
(2004)
Cancer Res.
, vol.64
, pp. 1140-1145
-
-
Blank, C.1
Brown, I.2
Peterson, A.C.3
Spiotto, M.4
Iwai, Y.5
Honjo, T.6
-
20
-
-
84862903106
-
Safety and activity of anti-PDL1 antibody in patients with advanced cancer
-
PMID: 22658128
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, et al. Safety and activity of anti-PDL1 antibody in patients with advanced cancer. N Engl J Med. 2012; 366: 2455-2465. doi: 10.1056/ NEJMoa1200694 PMID: 22658128
-
(2012)
N Engl J Med.
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
-
21
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
PMID: 22658127
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012; 366: 2443-2454. doi: 10.1056/ NEJMoa1200690 PMID: 22658127
-
(2012)
N Engl J Med.
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
22
-
-
78149491097
-
Blockade of programmed death-1 pathway rescues the effector function of tumor-infiltrating T cells and enhances the antitumor efficacy of lentivector immunization
-
PMID: 20926790
-
Zhou Q, Xiao H, Liu Y, Peng Y, Hong Y, Yagita H, et al. Blockade of programmed death-1 pathway rescues the effector function of tumor-infiltrating T cells and enhances the antitumor efficacy of lentivector immunization. J Immunol. 2010; 185: 5082-5092. doi: 10.4049/jimmunol.1001821 PMID: 20926790
-
(2010)
J Immunol.
, vol.185
, pp. 5082-5092
-
-
Zhou, Q.1
Xiao, H.2
Liu, Y.3
Peng, Y.4
Hong, Y.5
Yagita, H.6
-
23
-
-
84887862839
-
A rheostat for immune responses: The unique properties of PD-1 and their advantages for clinical application
-
PMID: 24240160
-
Okazaki T, Chikuma S, Iwai Y, Fagarasan S, Honjo T. A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application. Nat Immunol. 2013; 14: 1212-1218. doi: 10.1038/ni.2762 PMID: 24240160
-
(2013)
Nat Immunol.
, vol.14
, pp. 1212-1218
-
-
Okazaki, T.1
Chikuma, S.2
Iwai, Y.3
Fagarasan, S.4
Honjo, T.5
-
24
-
-
0037477605
-
The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice
-
PMID: 12847137
-
Ansari MJ, Salama AD, Chitnis T, Smith RN, Yagita H, Akiba H, et al. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med. 2003; 198: 63-69. doi: 10.1084/jem.20022125 PMID: 12847137
-
(2003)
J Exp Med.
, vol.198
, pp. 63-69
-
-
Ansari, M.J.1
Salama, A.D.2
Chitnis, T.3
Smith, R.N.4
Yagita, H.5
Akiba, H.6
-
25
-
-
14944360112
-
Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4
-
PMID: 15685176
-
Probst HC, McCoy K, Okazaki T, Honjo T, van den Broek M. Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4. Nat Immunol. 2005; 6: 280-286. doi: 10.1038/ni1165 PMID: 15685176
-
(2005)
Nat Immunol.
, vol.6
, pp. 280-286
-
-
Probst, H.C.1
McCoy, K.2
Okazaki, T.3
Honjo, T.4
Van Den Broek, M.5
-
26
-
-
0033554726
-
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
-
PMID: 10537110
-
Sallusto F, Lenig D, Förster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999; 401: 708-712. doi: 10.1038/44385 PMID: 10537110
-
(1999)
Nature
, vol.401
, pp. 708-712
-
-
Sallusto, F.1
Lenig, D.2
Förster, R.3
Lipp, M.4
Lanzavecchia, A.5
-
27
-
-
0035477154
-
Migratory properties of naive, effector, and memory CD8(+) T cells
-
PMID: 11581317
-
Weninger W, Crowley MA, Manjunath N, von Andrian UH. Migratory properties of naive, effector, and memory CD8(+) T cells. J Exp Med. 2001; 194: 953-966. doi: 10.1084/jem.194.7.953 PMID: 11581317
-
(2001)
J Exp Med.
, vol.194
, pp. 953-966
-
-
Weninger, W.1
Crowley, M.A.2
Manjunath, N.3
Von Andrian, U.H.4
-
28
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
PMID: 8287475
-
Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, Carbone FR. T cell receptor antagonist peptides induce positive selection. Cell. 1994; 76: 17-27. doi: 10.1016/0092-8674(94)90169-4 PMID: 8287475
-
(1994)
Cell.
, vol.76
, pp. 17-27
-
-
Hogquist, K.A.1
Jameson, S.C.2
Heath, W.R.3
Howard, J.L.4
Bevan, M.J.5
Carbone, F.R.6
-
29
-
-
33846938773
-
Cognate CD4+ help elicited by resting dendritic cells does not impair the induction of peripheral tolerance in CD8+ T cells
-
PMID: 17277113
-
Steptoe RJ, Ritchie JM, Wilson NS, Villadangos JA, Lew AM, Harrison LC. Cognate CD4+ help elicited by resting dendritic cells does not impair the induction of peripheral tolerance in CD8+ T cells. JI. 2007; 178: 2094-2103. doi: 10.4049/jimmunol.178.4.2094 PMID: 17277113
-
(2007)
JI.
, vol.178
, pp. 2094-2103
-
-
Steptoe, R.J.1
Ritchie, J.M.2
Wilson, N.S.3
Villadangos, J.A.4
Lew, A.M.5
Harrison, L.C.6
-
30
-
-
84871121537
-
A combination of local inflammation and central memory T cells potentiates immunotherapy in the skin
-
PMID: 23144496
-
Fiorenza S, Kenna TJ, Comerford I, McColl S, Steptoe RJ, Leggatt GR, et al. A combination of local inflammation and central memory T cells potentiates immunotherapy in the skin. J Immunol 2012; 189: 5622-5631. PMID: 23144496
-
(2012)
J Immunol
, vol.189
, pp. 5622-5631
-
-
Fiorenza, S.1
Kenna, T.J.2
Comerford, I.3
McColl, S.4
Steptoe, R.J.5
Leggatt, G.R.6
-
31
-
-
0030005099
-
Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
-
PMID 8671665
-
Agata A, Kawasaki Y, Nishimura H, Ishida Y, Tsubata T, Yagita H, et al. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol. 1996.; 8: 765-772. doi: 10. 1093/intimm/8.5.765 PMID: 8671665
-
(1996)
Int Immunol.
, vol.8
, pp. 765-772
-
-
Agata, A.1
Kawasaki, Y.2
Nishimura, H.3
Ishida, Y.4
Tsubata, T.5
Yagita, H.6
-
32
-
-
0242559053
-
Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis
-
PMID: 14579280
-
Rodig N, Ryan T, Allen JA, Pang H, Grabie N, Chernova T, et al. Endothelial expression of PD-L1 and PD-L2 down-regulates CD8+ T cell activation and cytolysis. Eur J Immunol. 2003; 33: 3117-3126. doi: 10.1002/eji.200324270 PMID: 14579280
-
(2003)
Eur J Immunol.
, vol.33
, pp. 3117-3126
-
-
Rodig, N.1
Ryan, T.2
Allen, J.A.3
Pang, H.4
Grabie, N.5
Chernova, T.6
-
33
-
-
77954492467
-
Premature terminal exhaustion of Friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors
-
PMID: 20351188
-
Takamura S, Tsuji-Kawahara S, Yagita H, Akiba H, Sakamoto M, Chikaishi T, et al. Premature terminal exhaustion of Friend virus-specific effector CD8+ T cells by rapid induction of multiple inhibitory receptors. J Immunol. 2010; 184: 4696-4707. doi: 10.4049/jimmunol.0903478 PMID: 20351188
-
(2010)
J Immunol.
, vol.184
, pp. 4696-4707
-
-
Takamura, S.1
Tsuji-Kawahara, S.2
Yagita, H.3
Akiba, H.4
Sakamoto, M.5
Chikaishi, T.6
-
34
-
-
0037446643
-
CD4+ T cells pass through an effector phase during the process of in vivo tolerance induction
-
PMID 12682221
-
Huang CT, Huso DL, Lu Z, Wang T, Zhou G, Kennedy EP, et al. CD4+ T cells pass through an effector phase during the process of in vivo tolerance induction. J Immunol. 2003; 170: 3945-3953. doi: 10. 4049/jimmunol.170.8.3945 PMID: 12682221
-
(2003)
J Immunol.
, vol.170
, pp. 3945-3953
-
-
Huang, C.T.1
Huso, D.L.2
Lu, Z.3
Wang, T.4
Zhou, G.5
Kennedy, E.P.6
-
35
-
-
0035903328
-
Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen
-
PMID: 11560988
-
Hernandez J, Aung S, Redmond WL, Sherman LA. Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen. J Exp Med. 2001; 194: 707-717. doi: 10.1084/jem.194.6.707 PMID: 11560988
-
(2001)
J Exp Med.
, vol.194
, pp. 707-717
-
-
Hernandez, J.1
Aung, S.2
Redmond, W.L.3
Sherman, L.A.4
-
36
-
-
2942736985
-
Transient gain of effector function by CD8+ T cells undergoing peripheral tolerance to high-dose self-antigen
-
PMID: 15114668
-
Huang X, Yang Y. Transient gain of effector function by CD8+ T cells undergoing peripheral tolerance to high-dose self-antigen. Eur J Immunol. 2004; 34: 1351-1360. doi: 10.1002/eji.200324734 PMID: 15114668
-
(2004)
Eur J Immunol.
, vol.34
, pp. 1351-1360
-
-
Huang, X.1
Yang, Y.2
-
37
-
-
34447646310
-
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
-
111-122 PMID: 17629517
-
Butte MJ, Keir ME, Phamduy TB, Sharpe AH, Freeman GJ. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity. 2007; 27 (1):111-22: 111-122. doi: 10.1016/j.immuni.2007.05.016 PMID: 17629517
-
(2007)
Immunity.
, vol.27
, Issue.1
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
Sharpe, A.H.4
Freeman, G.J.5
-
38
-
-
84873662718
-
A potential new pathway for PD-L1 costimulation of the CD8-T cell response to Listeria monocytogenes infection
-
PMID: 23409193
-
Xu D, Fu HH, Obar JJ, Park JJ, Tamada K, Yagita H, et al. A potential new pathway for PD-L1 costimulation of the CD8-T cell response to Listeria monocytogenes infection. PLoS One. 2013; 8: e56539. doi: 10.1371/journal.pone.0056539 PMID: 23409193
-
(2013)
PLoS One.
, vol.8
, pp. e56539
-
-
Xu, D.1
Fu, H.H.2
Obar, J.J.3
Park, J.J.4
Tamada, K.5
Yagita, H.6
-
39
-
-
77956496386
-
B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance
-
PMID: 20472828
-
Park JJ, Omiya R, Matsumura Y, Sakoda Y, Kuramasu A, Augustine MM, et al. B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance. Blood. 2010; 116: 1291-1298. doi: 10.1182/blood-2010-01-265975 PMID: 20472828
-
(2010)
Blood.
, vol.116
, pp. 1291-1298
-
-
Park, J.J.1
Omiya, R.2
Matsumura, Y.3
Sakoda, Y.4
Kuramasu, A.5
Augustine, M.M.6
-
40
-
-
3242677686
-
PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells
-
PMID: 15249675
-
Latchman YE, Liang SC, Wu Y, Chernova T, Sobel RA, Klemm M, et al. PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells. Proc Natl Acad Sci U S A. 2004; 101: 10691-10696. doi: 10.1073/pnas.0307252101 PMID: 15249675
-
(2004)
Proc Natl Acad Sci USA.
, vol.101
, pp. 10691-10696
-
-
Latchman, Y.E.1
Liang, S.C.2
Wu, Y.3
Chernova, T.4
Sobel, R.A.5
Klemm, M.6
-
41
-
-
80051619906
-
The programmed death-1 ligand 1:B7-1 pathway restrains diabetogenic effector T cells in vivo
-
PMID: 21697456
-
Paterson AM, Brown KE, Keir ME, Vanguri VK, Riella LV, Chandraker A, et al. The programmed death-1 ligand 1:B7-1 pathway restrains diabetogenic effector T cells in vivo. J Immunol. 2011; 187: 1097-1105. doi: 10.4049/jimmunol.1003496 PMID: 21697456
-
(2011)
J Immunol.
, vol.187
, pp. 1097-1105
-
-
Paterson, A.M.1
Brown, K.E.2
Keir, M.E.3
Vanguri, V.K.4
Riella, L.V.5
Chandraker, A.6
-
42
-
-
33748881940
-
Contribution of the PD-1 ligands/ PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation
-
PMID: 16917960
-
Kuipers H, Muskens F, Willart M, Hijdra D, van Assema FB, Coyle AJ, et al. Contribution of the PD-1 ligands/ PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation. Eur J Immunol. 2006; 36: 2472-2482. doi: 10.1002/eji.200635978 PMID: 16917960
-
(2006)
Eur J Immunol.
, vol.36
, pp. 2472-2482
-
-
Kuipers, H.1
Muskens, F.2
Willart, M.3
Hijdra, D.4
Van Assema, F.B.5
Coyle, A.J.6
-
43
-
-
34848852256
-
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection
-
PMID: 17878315
-
Mueller SN, Matloubian M, Clemens DM, Sharpe AH, Freeman GJ, Gangappa S, et al. Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proc Natl Acad Sci U S A. 2007; 104: 15430-15435. doi: 10.1073/pnas.0702579104 PMID: 17878315
-
(2007)
Proc Natl Acad Sci USA.
, vol.104
, pp. 15430-15435
-
-
Mueller, S.N.1
Matloubian, M.2
Clemens, D.M.3
Sharpe, A.H.4
Freeman, G.J.5
Gangappa, S.6
-
44
-
-
33748098860
-
PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and-gamma and mediates T cell apoptosis
-
PMID: 16876901
-
Mühlbauer M, Fleck M, Schütz C, Weiss T, Froh M, Blank C, et al. PD-L1 is induced in hepatocytes by viral infection and by interferon-alpha and-gamma and mediates T cell apoptosis. J Hepatol. 2006; 45: 520-528. doi: 10.1016/j.jhep.2006.05.007 PMID: 16876901
-
(2006)
J Hepatol.
, vol.45
, pp. 520-528
-
-
Mühlbauer, M.1
Fleck, M.2
Schütz, C.3
Weiss, T.4
Froh, M.5
Blank, C.6
-
45
-
-
31444451661
-
Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274
-
PMID: 16413538
-
Lee SJ, Jang BC, Lee SW, Yang YI, Suh SI, Park YM, et al. Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274). FEBS Lett. 2006; 580: 755-762. doi: 10.1016/j.febslet.2005.12.093 PMID: 16413538
-
(2006)
FEBS Lett.
, vol.580
, pp. 755-762
-
-
Lee, S.J.1
Jang, B.C.2
Lee, S.W.3
Yang, Y.I.4
Suh, S.I.5
Park, Y.M.6
-
46
-
-
44449142522
-
Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway
-
PMID: 18354207
-
Benedict CA, Loewendorf A, Garcia Z, Blazar BR, Janssen EM. Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway. J Immunol. 2008; 180: 4836-4847. doi: 10.4049/jimmunol.180.7.4836 PMID: 18354207
-
(2008)
J Immunol.
, vol.180
, pp. 4836-4847
-
-
Benedict, C.A.1
Loewendorf, A.2
Garcia, Z.3
Blazar, B.R.4
Janssen, E.M.5
-
47
-
-
57849168934
-
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
-
PMID: 19043418
-
Blackburn SD, Shin H, Haining WN, Zou T, Workman CJ, Polley A, et al. Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. Nat Immunol. 2009; 10: 29-37. doi: 10.1038/ni.1679 PMID: 19043418
-
(2009)
Nat Immunol.
, vol.10
, pp. 29-37
-
-
Blackburn, S.D.1
Shin, H.2
Haining, W.N.3
Zou, T.4
Workman, C.J.5
Polley, A.6
-
48
-
-
0038325761
-
Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance
-
PMID: 12753747
-
Probst HC, Lagnel J, Kollias G, van den Broek M. Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance. Immunity. 2003; 18: 713-720. doi: 10.1016/S1074-7613(03)00120-1 PMID: 12753747
-
(2003)
Immunity.
, vol.18
, pp. 713-720
-
-
Probst, H.C.1
Lagnel, J.2
Kollias, G.3
Van Den Broek, M.4
-
49
-
-
16844379997
-
Immunosuppressive networks in the tumour environment and their therapeutic relevance
-
PMID: 15776005
-
Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer. 2005; 5: 263-274. doi: 10.1038/nrc1586 PMID: 15776005
-
(2005)
Nat Rev Cancer.
, vol.5
, pp. 263-274
-
-
Zou, W.1
-
50
-
-
77957744369
-
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
-
PMID: 20819927
-
Sakuishi K, Apetoh L, Sullivan JM, Blazar BR, Kuchroo VK, Anderson AC. Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med. 2010; 207: 2187-2194. doi: 10.1084/jem.20100643 PMID: 20819927
-
(2010)
J Exp Med.
, vol.207
, pp. 2187-2194
-
-
Sakuishi, K.1
Apetoh, L.2
Sullivan, J.M.3
Blazar, B.R.4
Kuchroo, V.K.5
Anderson, A.C.6
-
51
-
-
77749279776
-
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
-
PMID: 20160101
-
Curran MA, Montalvo W, Yagita H, Allison JP. PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors. Proc Natl Acad Sci U S A. 2010; 107: 4275-4280. doi: 10.1073/pnas.0915174107 PMID: 20160101
-
(2010)
Proc Natl Acad Sci USA.
, vol.107
, pp. 4275-4280
-
-
Curran, M.A.1
Montalvo, W.2
Yagita, H.3
Allison, J.P.4
-
52
-
-
84872535167
-
Durable adoptive immunotherapy for leukemia produced by manipulation of multiple regulatory pathways of CD8+ T-cell tolerance
-
PMID: 23188506
-
Berrien-Elliott MM, Jackson SR, Meyer JM, Rouskey CJ, Nguyen TL, Yagita H, et al. Durable adoptive immunotherapy for leukemia produced by manipulation of multiple regulatory pathways of CD8+ T-cell tolerance. Cancer Research. 2013; 73: 605-616. doi: 10.1158/0008-5472.CAN-12-2179 PMID: 23188506
-
(2013)
Cancer Research.
, vol.73
, pp. 605-616
-
-
Berrien-Elliott, M.M.1
Jackson, S.R.2
Meyer, J.M.3
Rouskey, C.J.4
Nguyen, T.L.5
Yagita, H.6
-
53
-
-
77951637543
-
Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma
-
PMID: 20194714
-
Pilon-Thomas S, Mackay A, Vohra N, J.J. M. Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma. J Immunol. 2010; 184: 3442-3449. doi: 10.4049/jimmunol.0904114 PMID: 20194714
-
(2010)
J Immunol.
, vol.184
, pp. 3442-3449
-
-
Pilon-Thomas, S.1
Mackay, A.2
Vohra, N.J.J.M.3
-
54
-
-
76249090050
-
Dual control of antitumor CD8 T cells through the programmed death-1/programmed death-ligand 1 pathway and immunosuppressive CD4 T cells: Regulation and counterregulation
-
PMID 20007574
-
Currie AJ, Prosser A, McDonnell A, Cleaver AL, Robinson BW, Freeman GJ, et al. Dual control of antitumor CD8 T cells through the programmed death-1/programmed death-ligand 1 pathway and immunosuppressive CD4 T cells: regulation and counterregulation. J Immunol. 2009; 183: 7898-7908. doi: 10. 4049/jimmunol.0901060 PMID: 20007574
-
(2009)
J Immunol.
, vol.183
, pp. 7898-7908
-
-
Currie, A.J.1
Prosser, A.2
McDonnell, A.3
Cleaver, A.L.4
Robinson, B.W.5
Freeman, G.J.6
-
55
-
-
79960732805
-
Combination of lentivector immunization and low-dose chemotherapy or PD-1/PD-L1 blocking primes self-reactive T cells and induces anti-tumor immunity
-
Sierro SR, Donda A, Perret R, Guillaume P, Yagita H, Levy F, et al. Combination of lentivector immunization and low-dose chemotherapy or PD-1/PD-L1 blocking primes self-reactive T cells and induces anti-tumor immunity. Eur J Immunol. 2011; 41: 221-2228. doi: 10.1002/eji.201041235
-
(2011)
Eur J Immunol.
, vol.41
, pp. 221-2228
-
-
Sierro, S.R.1
Donda, A.2
Perret, R.3
Guillaume, P.4
Yagita, H.5
Levy, F.6
-
56
-
-
84867544962
-
PD-1 blockade enhances T-cell migration to tumors by elevating IFN- inducible chemokines
-
PMID: 22915761
-
Peng W, Liu C, Xu C, Lou Y, Chen J, Yang Y, et al. PD-1 blockade enhances T-cell migration to tumors by elevating IFN-? inducible chemokines. Cancer Research. 2012; 72: 5209-5218. doi: 10.1158/0008-5472.CAN-12-1187 PMID: 22915761
-
(2012)
Cancer Research.
, vol.72
, pp. 5209-5218
-
-
Peng, W.1
Liu, C.2
Xu, C.3
Lou, Y.4
Chen, J.5
Yang, Y.6
-
57
-
-
84893876109
-
Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice
-
PMID: 24382348
-
Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum RR, et al. Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J Clin Invest. 2014; 124: 687-695. doi: 10.1172/JCI67313 PMID: 24382348
-
(2014)
J Clin Invest.
, vol.124
, pp. 687-695
-
-
Deng, L.1
Liang, H.2
Burnette, B.3
Beckett, M.4
Darga, T.5
Weichselbaum, R.R.6
-
58
-
-
77957747417
-
Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia
-
PMID: 20570856
-
Zhou Q, Munger ME, Highfill SL, Tolar J, Weigel BJ, Riddle M, et al. Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia. Blood. 2010; 116: 2484-2493. doi: 10.1182/blood-2010-03-275446 PMID: 20570856
-
(2010)
Blood.
, vol.116
, pp. 2484-2493
-
-
Zhou, Q.1
Munger, M.E.2
Highfill, S.L.3
Tolar, J.4
Weigel, B.J.5
Riddle, M.6
-
59
-
-
84886397930
-
Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells
-
PMID: 23873688
-
John LB, Devaud C, Duong CP, Yong CS, Beavis PA, Haynes NM, et al. Anti-PD-1 antibody therapy potently enhances the eradication of established tumors by gene-modified T cells. Clin Cancer Res. 2013; 19(20):. 5636-5646. doi: 10.1158/1078-0432.CCR-13-0458 PMID: 23873688
-
(2013)
Clin Cancer Res.
, vol.19
, Issue.20
, pp. 5636-5646
-
-
John, L.B.1
Devaud, C.2
Duong, C.P.3
Yong, C.S.4
Beavis, P.A.5
Haynes, N.M.6
-
60
-
-
61449267507
-
Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade
-
PMID: 19201863
-
Reynoso ED, Elpek KG, Francisco L, Bronson R, Bellemare-Pelletier A, Sharpe AH, et al. Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade. J Immunol. 2009; 182: 2102-2112. doi: 10.4049/jimmunol.0802769 PMID: 19201863
-
(2009)
J Immunol.
, vol.182
, pp. 2102-2112
-
-
Reynoso, E.D.1
Elpek, K.G.2
Francisco, L.3
Bronson, R.4
Bellemare-Pelletier, A.5
Sharpe, A.H.6
-
61
-
-
77954801079
-
Improved survival with Ipilimumab in patients with metastatic melanoma
-
PMID: 20525992
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, et al. Improved survival with Ipilimumab in patients with metastatic melanoma. N Engl J Med. 2010; 363: 711-723. doi: 10.1056/ NEJMoa1003466 PMID: 20525992
-
(2010)
N Engl J Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
|