IL-1 receptor blockade alleviates endotoxin-mediated impairment of renal drug excretory functions in rats

American Journal of Physiology - Renal Physiology

Volumn 308, Issue 5, 2015, Pages F388-F399

  Kadova, Zuzana ^a   Dolezelova, Eva ^a   Cermanova, Jolana ^a   Hroch, Milos ^a   Laho, Tomas ^a   Muchova, Lucie ^a   Staud, Frantisek ^a   Vitek, Libor ^a   Mokry, Jaroslav ^a   Chladek, Jaroslav ^a   Havlinova, Zuzana ^a   Holecek, Milan ^a   Micuda, Stanislav ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Acute kidney injury; Anakinra; Dexamethasone; Drug transporters; Endotoxins

Indexed keywords

AZITHROMYCIN; BETA ACTIN; BILE ACID; DEXAMETHASONE; ENDOTOXIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1 RECEPTOR; LIPOPOLYSACCHARIDE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 2; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SODIUM; UREA; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; XENOBIOTIC AGENT;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG ELIMINATION; DRUG EXCRETION; DRUG POTENCY; ENDOTOXEMIA; GLOMERULUS FILTRATION RATE; KIDNEY CLEARANCE; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE EXCRETION; LIVER INJURY; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEPSIS; SIGNAL TRANSDUCTION; ACUTE KIDNEY INJURY; ANIMAL; COMPLICATION; DRUG EFFECTS; URINARY EXCRETION; WISTAR RAT;

ACUTE KIDNEY INJURY; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; AZITHROMYCIN; DEXAMETHASONE; ENDOTOXEMIA; ENDOTOXINS; GLOMERULAR FILTRATION RATE; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; LIPOPOLYSACCHARIDES; MALE; RATS, WISTAR; RENAL ELIMINATION; XENOBIOTICS;

EID: 84924075862     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00266.2014     Document Type: Article

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