Changes in digoxin pharmacokinetics treated with lipopolysaccharide in wistar rats

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 6, 2008, Pages 1221-1225

  Kato, Ryuji ^a   Fujiwara, Azusa ^a   Kawai, Takako ^a   Moriguchi, Jun ^a   Nakagawa, Machiko ^a   Tsukura, Yuri ^a   Uchida, Kagehiro ^b   Amano, Fumio ^a   Hirotani, Yoshihiko ^c   Ijiri, Yoshio ^a   Tanaka, Kazuhiko ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Biomarker Science Co Ltd   (Japan)

^c OSAKA OHTANI UNIVERSITY   (Japan)

Author keywords

Absorption; Digoxin; Distribution; Lipopolysaccharide

Indexed keywords

DIGOXIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BLOOD PRESSURE; BODY TEMPERATURE DISORDER; COMPARTMENT MODEL; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; ENDOTOXEMIA; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT;

ADMINISTRATION, ORAL; ALGORITHMS; ANIMALS; AREA UNDER CURVE; BLOOD PRESSURE; BODY TEMPERATURE; CARDIOTONIC AGENTS; CYTOKINES; DIGOXIN; ENDOTOXEMIA; ESCHERICHIA COLI; INJECTIONS, INTRAVENOUS; INTERLEUKIN-1BETA; INTESTINAL ABSORPTION; INTESTINES; LIPOPOLYSACCHARIDES; MALE; RATS; RATS, WISTAR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 45749106752     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.1221     Document Type: Article

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