Low-dose dexamethasone-supplemented fluid resuscitation reverses endotoxin-induced acute renal failure and prevents cortical microvascular hypoxia

Shock

Volumn 31, Issue 5, 2009, Pages 521-528

  Johannes, Tanja ^a,b   Mik, Egbert G ^a,c   Klingel, Karin ^b   Dieterich, Hans Jürgen ^b   Unertl, Klaus E ^b   Ince, Can ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Glucocorticoid; iNOS; NO; Oxygen histogram; Oxygenation; Septic renal failure

Indexed keywords

DEXAMETHASONE; ENDOTOXIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; OXYGEN;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; CONTROLLED STUDY; CONVALESCENCE; DOSE RESPONSE; ENDOTOXEMIA; ENZYME INHIBITION; FLUID RESUSCITATION; GENE EXPRESSION; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY TUBULE; LOW DRUG DOSE; MALE; MICROANGIOPATHY; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN DELIVERY DEVICE; OXYGENATION; RAT; SEPTIC SHOCK; SODIUM ABSORPTION; ANIMAL; ANOXIA; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; HEMODYNAMICS; KIDNEY CORTEX; KIDNEY FUNCTION TEST; METABOLISM; MICROCIRCULATION; PATHOPHYSIOLOGY; RESUSCITATION; VASCULARIZATION; WISTAR RAT;

ANIMALS; ANOXIA; DEXAMETHASONE; ENDOTOXINS; HEMODYNAMICS; KIDNEY CORTEX; KIDNEY FAILURE, ACUTE; KIDNEY FUNCTION TESTS; MALE; MICROCIRCULATION; OXYGEN; RATS; RATS, WISTAR; RESUSCITATION;

EID: 67649386390     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318188d198     Document Type: Article

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